Huifen Chen

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 12

Top Venues

Journal of medicinal chemistry

Chemical research in toxicology

Expert opinion on therapeutic patents

ACS medicinal chemistry letters

This page only lists publications with an associated author ORCID identifier.

Publications

Jack A Terrett, Justin Q Ly, Paula Katavolos, Catrin Hasselgren, Steven Laing, Fiona Zhong, Elisia Villemure, Martin Déry, Robin Larouche-Gauthier, Huifen Chen, Daniel G Shore, Wyne P Lee, Eric Suto, Kevin M Johnson, Marjory Brooks, Alyssa Stablein, Francis Beaumier, Léa Constantineau-Forget, Chantal Grand-Maître, Luce Lépissier, Stéphane Ciblat, Claudio Sturino, Yong Chen, Baihua Hu, Justin Elstrott, Vineela Gandham, Victory Joseph, Helen Booler, Gary Cain, Carolina Chou, Aaron Fullerton, Michelle Lepherd, Shannon Stainton, Elizabeth Torres, Konnie Urban, Lanlan Yu, Yu Zhong, Linda Bao, Kang-Jye Chou, Jessica Lin, Wei Zhang, Hank La, Liling Liu, Teresa Mulder, Jun Chen, Tania Chernov-Rogan, Adam R Johnson, David H Hackos, Rebecca Leahey, Shannon D Shields, Alessia Balestrini, Lorena Riol-Blanco, Brian S Safina, Matthew Volgraf, Steven Magnuson, Satoko Kakiuchi-Kiyota
Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease. Journal of medicinal chemistry 67 (5) (2024)
Michael Berlin, Jennifer Cantley, Mark Bookbinder, Elizabeth Bortolon, Fabio Broccatelli, Greg Cadelina, Emily W Chan, Huifen Chen, Xin Chen, Yunxing Cheng, Tommy K Cheung, Kim Davenport, Dean DiNicola, Debbie Gordon, Brian D Hamman, Alicia Harbin, Roy Haskell, Mingtao He, Alison J Hole, Thomas Januario, Philip S Kerry, Stefan G Koenig, Limei Li, Mark Merchant, Inmaculada Pérez-Dorado, Jennifer Pizzano, Connor Quinn, Christopher M Rose, Emma Rousseau, Leofal Soto, Leanna R Staben, Hongming Sun, Qingping Tian, Jing Wang, Weifeng Wang, Crystal S Ye, Xiaofen Ye, Penghong Zhang, Yuhui Zhou, Robert Yauch, Peter S Dragovich
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. Journal of medicinal chemistry (2024)
Jack A Terrett, Justin Q Ly, Paula Katavolos, Catrin Hasselgren, Steven Laing, Fiona Zhong, Elisia Villemure, Martin Déry, Robin Larouche-Gauthier, Huifen Chen, Daniel G Shore, Wyne P Lee, Eric Suto, Kevin M Johnson, Marjory Brooks, Alyssa Stablein, Francis Beaumier, Léa Constantineau-Forget, Chantal Grand-Maître, Luce Lépissier, Stéphane Ciblat, Claudio Sturino, Yong Chen, Baihua Hu, Justin Elstrott, Vineela Gandham, Victory Joseph, Helen Booler, Gary Cain, Carolina Chou, Aaron Fullerton, Michelle Lepherd, Shannon Stainton, Elizabeth Torres, Konnie Urban, Lanlan Yu, Yu Zhong, Linda Bao, Kang-Jye Chou, Jessica Lin, Wei Zhang, Hank La, Liling Liu, Teresa Mulder, Jun Chen, Tania Chernov-Rogan, Adam R Johnson, David H Hackos, Rebecca Leahey, Shannon D Shields, Alessia Balestrini, Lorena Riol-Blanco, Brian S Safina, Matthew Volgraf, Steven Magnuson, Satoko Kakiuchi-Kiyota
Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease. Journal of medicinal chemistry (2024)
Jack A Terrett, Justin Q Ly, Paula Katavolos, Catrin Hasselgren, Steven Laing, Fiona Zhong, Elisia Villemure, Martin Déry, Robin Larouche-Gauthier, Huifen Chen, Daniel G Shore, Wyne P Lee, Eric Suto, Kevin M Johnson, Marjory Brooks, Alyssa Stablein, Francis Beaumier, Léa Constantineau-Forget, Chantal Grand-Maître, Luce Lépissier, Stéphane Ciblat, Claudio Sturino, Yong Chen, Baihua Hu, Justin Elstrott, Vineela Gandham, Victory Joseph, Helen Booler, Gary Cain, Carolina Chou, Aaron Fullerton, Michelle Lepherd, Shannon Stainton, Elizabeth Torres, Konnie Urban, Lanlan Yu, Yu Zhong, Linda Bao, Kang-Jye Chou, Jessica Lin, Wei Zhang, Hank La, Liling Liu, Teresa Mulder, Jun Chen, Tania Chernov-Rogan, Adam R Johnson, David H Hackos, Rebecca Leahey, Shannon D Shields, Alessia Balestrini, Lorena Riol-Blanco, Brian S Safina, Matthew Volgraf, Steven Magnuson, Satoko Kakiuchi-Kiyota
Discovery of TRPA1 Antagonist GDC-6599 : Derisking Preclinical Toxicity and Aldehyde Oxidase Metabolism with a Potential First-in-Class Therapy for Respiratory Disease. Journal of medicinal chemistry 67 (5) (2024)
Michael Berlin, Jennifer Cantley, Mark Bookbinder, Elizabeth Bortolon, Fabio Broccatelli, Greg Cadelina, Emily W Chan, Huifen Chen, Xin Chen, Yunxing Cheng, Tommy K Cheung, Kim Davenport, Dean DiNicola, Debbie Gordon, Brian D Hamman, Alicia Harbin, Roy Haskell, Mingtao He, Alison J Hole, Thomas Januario, Philip S Kerry, Stefan G Koenig, Limei Li, Mark Merchant, Inmaculada Pérez-Dorado, Jennifer Pizzano, Connor Quinn, Christopher M Rose, Emma Rousseau, Leofal Soto, Leanna R Staben, Hongming Sun, Qingping Tian, Jing Wang, Weifeng Wang, Crystal S Ye, Xiaofen Ye, Penghong Zhang, Yuhui Zhou, Robert Yauch, Peter S Dragovich
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. Journal of medicinal chemistry 67 (2) (2024)
Michael Berlin, Jennifer Cantley, Mark Bookbinder, Elizabeth Bortolon, Fabio Broccatelli, Greg Cadelina, Emily W Chan, Huifen Chen, Xin Chen, Yunxing Cheng, Tommy K Cheung, Kim Davenport, Dean DiNicola, Debbie Gordon, Brian D Hamman, Alicia Harbin, Roy Haskell, Mingtao He, Alison J Hole, Thomas Januario, Philip S Kerry, Stefan G Koenig, Limei Li, Mark Merchant, Inmaculada Pérez-Dorado, Jennifer Pizzano, Connor Quinn, Christopher M Rose, Emma Rousseau, Leofal Soto, Leanna R Staben, Hongming Sun, Qingping Tian, Jing Wang, Weifeng Wang, Crystal S Ye, Xiaofen Ye, Penghong Zhang, Yuhui Zhou, Robert Yauch, Peter S Dragovich
PROTACs Targeting BRM (SMARCA2) Afford Selective In Vivo Degradation over BRG1 (SMARCA4) and Are Active in BRG1 Mutant Xenograft Tumor Models. Journal of medicinal chemistry 67 (2) (2024)
Jack A Terrett, Huifen Chen, Daniel G Shore, Elisia Villemure, Robin Larouche-Gauthier, Martin Déry, Francis Beaumier, Léa Constantineau-Forget, Chantal Grand-Maître, Luce Lépissier, Stéphane Ciblat, Claudio Sturino, Yong Chen, Baihua Hu, Aijun Lu, Yunli Wang, Andrew P Cridland, Stuart I Ward, David H Hackos, Rebecca M Reese, Shannon D Shields, Jun Chen, Alessia Balestrini, Lorena Riol-Blanco, Wyne P Lee, John Liu, Eric Suto, Xiumin Wu, Juan Zhang, Justin Q Ly, Hank La, Kevin M Johnson, Matt Baumgardner, Kang-Jye Chou, Alexis Rohou, Lionel Rougé, Brian S Safina, Steven Magnuson, Matthew Volgraf
Tetrahydrofuran-Based Transient Receptor Potential Ankyrin 1 (TRPA1) Antagonists: Ligand-Based Discovery, Activity in a Rodent Asthma Model, and Mechanism-of-Action via Cryogenic Electron Microscopy. Journal of medicinal chemistry 64 (7) (2021)
Elisia Villemure, Jack A Terrett, Robin Larouche-Gauthier, Martin Déry, Huifen Chen, Rebecca M Reese, Shannon D Shields, Jun Chen, Steven Magnuson, Matthew Volgraf
A Retrospective Look at the Impact of Binding Site Environment on the Optimization of TRPA1 Antagonists. ACS medicinal chemistry letters 12 (8) (2021)
Dennis X Hu, Snahel Patel, Huifen Chen, Shumei Wang, Steven T Staben, Yoana N Dimitrova, Heidi Ackerly Wallweber, Joanna Y Lee, Grace Ka Yan Chan, Christopher J Sneeringer, Madeleine S Prangley, John G Moffat, Kai C Wu, Leah K Schutt, Laurent Salphati, Jodie Pang, Erin McNamara, Haochu Huang, Yong Chen, Yunli Wang, Wensheng Zhao, Junghyun Lim, Aditya Murthy, Michael Siu
Structure-Based Design of Potent, Selective, and Orally Bioavailable VPS34 Kinase Inhibitors. Journal of medicinal chemistry (2021)
Chenghong Zhang, James J Crawford, Matthew L Landry, Huifen Chen, Jane R Kenny, S Cyrus Khojasteh, Wendy Lee, Shuguang Ma, Wendy B Young
Strategies to Mitigate the Bioactivation of Aryl Amines. Chemical research in toxicology 33 (7) (2020)
Huifen Chen, Jack A Terrett
Transient receptor potential ankyrin 1 (TRPA1) antagonists: a patent review (2015-2019). Expert opinion on therapeutic patents 30 (9) (2020)
Huifen Chen, Matthew Volgraf, Steven Do, Aleksandr Kolesnikov, Daniel G Shore, Vishal A Verma, Elisia Villemure, Lan Wang, Yong Chen, Baihua Hu, Ai-Jun Lu, Guosheng Wu, Xiaofeng Xu, Po-Wai Yuen, Yamin Zhang, Shawn D Erickson, Martin Dahl, Christine Brotherton-Pleiss, Suzanne Tay, Justin Q Ly, Lesley J Murray, Jun Chen, Desiree Amm, Wienke Lange, David H Hackos, Rebecca M Reese, Shannon D Shields, Joseph P Lyssikatos, Brian S Safina, Anthony A Estrada
Discovery of a Potent (4 R,5 S)-4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling. Journal of medicinal chemistry 61 (8) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Huifen Chen