Huihao Zhou

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 27

Top Venues

Journal of medicinal chemistry

Science advances

Nucleic acids research

Journal of natural products

Sun Yat-Sen University

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Sun Yat-Sen University

China

Professor :: School of Pharmaceutical Sciences

Scripps Research Institute

United States

Research Associate

Publications

Haopeng Ai, Deyin Wu, Huihao Zhou, Jun Xu, Qiong Gu
dMXP: A De Novo Small-Molecule 3D Structure Predictor with Graph Attention Networks. Journal of chemical information and modeling (2024)
Xing Peng, Zhikang Zhang, Yuting Zhang, Huihao Zhou, Wenqi Li, Minxian Dai, Jinsai Shang, Jun Xu, Qiong Gu
Discovery of Novel Neo -Clerodane Derivatives as Potent Dual-Functional Antiosteoporosis Agents through Targeting Peroxisome Proliferator-Activated Receptor-γ. Journal of medicinal chemistry (2024)
Haopeng Ai, Deyin Wu, Huihao Zhou, Jun Xu, Qiong Gu
dMXP: A De Novo Small-Molecule 3D Structure Predictor with Graph Attention Networks. Journal of chemical information and modeling 64 (9) (2024)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Manli Xiang, Kaijiang Xia, Bingyi Chen, Zhiteng Luo, Ying Yu, Lili Jiang, Huihao Zhou
An asymmetric structure of bacterial TrpRS supports the half-of-the-sites catalytic mechanism and facilitates antimicrobial screening. Nucleic acids research (2023)
Xing Peng, Qingyun Tan, Zhikang Zhang, Deyin Wu, Jun Xu, Huihao Zhou, Qiong Gu
Discovery of neo -Clerodane Diterpenoids from Ajuga campylantha as Neuroprotective Agents against Ferroptosis and Neuroinflammation. Journal of natural products (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Hao Chen, Pei Hua, Dane Huang, Yuting Zhang, Huihao Zhou, Jun Xu, Qiong Gu
Discovery of Spiro[pyrrolidine-3,3'-oxindole] LXRβ Agonists for the Treatment of Osteoporosis. Journal of medicinal chemistry 66 (1) (2022)
Zhengjun Cai, Bingyi Chen, Ying Yu, Junsong Guo, Zhiteng Luo, Bao Cheng, Jun Xu, Qiong Gu, Huihao Zhou
Design, Synthesis, and Proof-of-Concept of Triple-Site Inhibitors against Aminoacyl-tRNA Synthetases. Journal of medicinal chemistry 65 (7) (2022)
Bao Cheng, Zhengjun Cai, Ziqing Luo, Siting Luo, Zhiteng Luo, Yanfang Cheng, Ying Yu, Junsong Guo, Yingchen Ju, Qiong Gu, Jun Xu, Xianxing Jiang, Geng Li, Huihao Zhou
Structure-Guided Design of Halofuginone Derivatives as ATP-Aided Inhibitors Against Bacterial Prolyl-tRNA Synthetase. Journal of medicinal chemistry 65 (23) (2022)
Hao Chen, Pei Hua, Dane Huang, Yuting Zhang, Huihao Zhou, Jun Xu, Qiong Gu
Discovery of Spiro[pyrrolidine-3,3'-oxindole] LXRβ Agonists for the Treatment of Osteoporosis. Journal of medicinal chemistry 66 (1) (2022)
Jia Yi, Zhengjun Cai, Haipeng Qiu, Feihu Lu, Zhiteng Luo, Bingyi Chen, Qiong Gu, Jun Xu, Huihao Zhou
Fragment screening and structural analyses highlight the ATP-assisted ligand binding for inhibitor discovery against type 1 methionyl-tRNA synthetase. Nucleic acids research 50 (8) (2022)
Xing Peng, Qingyun Tan, Leiming Wu, Deyin Wu, Jun Xu, Huihao Zhou, Qiong Gu
Ferroptosis Inhibitory Aromatic Abietane Diterpenoids from Ajuga decumbens and Structural Revision of Two 3,4-Epoxy Group-Containing Abietanes. Journal of natural products 85 (7) (2022)
Zhejun Sun, Yuting Zhang, Xing Peng, Shijie Huang, Huihao Zhou, Jun Xu, Qiong Gu
Diverse Sesquiterpenoids and Polyacetylenes from Atractylodes lancea and Their Anti-Osteoclastogenesis Activity. Journal of natural products 85 (4) (2022)
Dane Huang, Chao Zhao, Ruyue Li, Bingyi Chen, Yuting Zhang, Zhejun Sun, Junkang Wei, Huihao Zhou, Qiong Gu, Jun Xu
Identification of a binding site on soluble RANKL that can be targeted to inhibit soluble RANK-RANKL interactions and treat osteoporosis. Nature communications 13 (1) (2022)
Hao Chen, Pei Hua, Dane Huang, Yuting Zhang, Huihao Zhou, Jun Xu, Qiong Gu
Discovery of Spiro[pyrrolidine-3,3'-oxindole] LXRβ Agonists for the Treatment of Osteoporosis. Journal of medicinal chemistry 66 (1) (2022)
Hao Chen, Pei Hua, Dane Huang, Yuting Zhang, Huihao Zhou, Jun Xu, Qiong Gu
Discovery of Spiro[pyrrolidine-3,3'-oxindole] LXRβ Agonists for the Treatment of Osteoporosis. Journal of medicinal chemistry (2022)
Yuying Fang, Xiucai Chen, Qingyun Tan, Huihao Zhou, Jun Xu, Qiong Gu
Inhibiting Ferroptosis through Disrupting the NCOA4-FTH1 Interaction: A New Mechanism of Action. ACS central science 7 (6) (2021)
Zhiteng Luo, Siting Luo, Yingchen Ju, Peng Ding, Jun Xu, Qiong Gu, Huihao Zhou
Structural insights into the ligand recognition and catalysis of the key aminobutanoyltransferase CntL in staphylopine biosynthesis. FASEB journal : official publication of the Federation of American Societies for Experimental Biology 35 (5) (2021)
Yingchen Ju, Lu Han, Bingyi Chen, Zhiteng Luo, Qiong Gu, Jun Xu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications. Nucleic acids research 49 (17) (2021)
Mengjiao Hao, Zhikang Zhang, Yijun Guo, Huihao Zhou, Qiong Gu, Jun Xu
Rubidium chloride increases lifespan through an AMPK/FOXO-dependent pathway in Caenorhabditis elegans. The journals of gerontology. Series A, Biological sciences and medical sciences (2021)
Mengyang Xu, Chao Zhao, Biying Zhu, Liangyue Wang, Huihao Zhou, Daoguang Yan, Qiong Gu, Jun Xu
Discovering High Potent Hsp90 Inhibitors as Antinasopharyngeal Carcinoma Agents through Fragment Assembling Approach. Journal of medicinal chemistry 64 (4) (2021)
Litao Sun, Na Wei, Bernhard Kuhle, David Blocquel, Scott J Novick, Zaneta Matuszek, Huihao Zhou, Weiwei He, Jingjing Zhang, Thomas Weber, Rita Horvath, Philippe Latour, Tao Pan, Paul Schimmel, Patrick R Griffin, Xiang-Lei Yang
CMT2N-causing aminoacylation domain mutants enable Nrp1 interaction with AlaRS. Proceedings of the National Academy of Sciences of the United States of America 118 (13) (2021)
Mengyang Xu, Biying Zhu, Xiuye Cao, Shannai Li, Dan Li, Huihao Zhou, Vesa M Olkkonen, Wenbin Zhong, Jun Xu, Daoguang Yan
OSBP-Related Protein 5L Maintains Intracellular IP3/Ca2+ Signaling and Proliferation in T Cells by Facilitating PIP2 Hydrolysis. Journal of immunology (Baltimore, Md. : 1950) 204 (5) (2020)
Jieyu Tang, Yingchen Ju, Jingwei Zhou, Junsong Guo, Qiong Gu, Jun Xu, Huihao Zhou
Structural and Biochemical Characterization of SbnC as a Representative Type B Siderophore Synthetase. ACS chemical biology 15 (10) (2020)

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Publication Activity (10 Years)

Top Topics

Top Venues

Huihao Zhou