Paul Schimmel

Publication Activity (10 Years)

Years Active: 2021-2023
Publications (10 Years): 13

Top Topics

Protein Protein

Molecular Dynamics

Top Venues

Science advances

Science translational medicine

Nature cell biology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Bernhard Kuhle, Marscha Hirschi, Lili K Doerfel, Gabriel C Lander, Paul Schimmel
Structural basis for a degenerate tRNA identity code and the evolution of bimodal specificity in human mitochondrial tRNA recognition. Nature communications 14 (1) (2023)
Haissi Cui, Jolene K Diedrich, Douglas C Wu, Justin J Lim, Ryan M Nottingham, James J Moresco, John Yates Iii, Benjamin J Blencowe, Alan M Lambowitz, Paul Schimmel
Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2. Nature cell biology 25 (4) (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Eva S Istvan, Francisco M Guerra, Matthew Abraham, Kuo-Sen Huang, Frances Rocamora, Haoshuang Zhao, Lan Xu, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Madeline R Luth, Haissi Cui, Tuo Yang, Sara Palomo Diaz, Maria G Gomez-Lorenzo, Tarrick Qahash, Nimisha Mittal, Sabine Ottilie, Jacquin C Niles, Marcus Chee San Lee, Manuel Llinás, Nobutaka Kato, John Okombo, David A Fidock, Paul Schimmel, Francisco Javier Gamo, Daniel E Goldberg, Elizabeth A Winzeler
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science translational medicine 15 (686) (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Eva S Istvan, Francisco M Guerra, Matthew Abraham, Kuo-Sen Huang, Frances Rocamora, Haoshuang Zhao, Lan Xu, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Madeline R Luth, Haissi Cui, Tuo Yang, Sara Palomo Diaz, Maria G Gomez-Lorenzo, Tarrick Qahash, Nimisha Mittal, Sabine Ottilie, Jacquin C Niles, Marcus Chee San Lee, Manuel Llinás, Nobutaka Kato, John Okombo, David A Fidock, Paul Schimmel, Francisco Javier Gamo, Daniel E Goldberg, Elizabeth A Winzeler
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science translational medicine 15 (686) (2023)
Bastiaan de Potter, Ingrid Vallee, Noelia Camacho, Luís Filipe Costa Póvoas, Aureliano Bonsembiante, Alba Pons I Pons, Ulrich Eckhard, Francesc-Xavier Gomis-Rüth, Xiang-Lei Yang, Paul Schimmel, Bernhard Kuhle, Lluís Ribas de Pouplana
Domain collapse and active site ablation generate a widespread animal mitochondrial seryl-tRNA synthetase. Nucleic acids research (2023)
Haissi Cui, Jolene K Diedrich, Douglas C Wu, Justin J Lim, Ryan M Nottingham, James J Moresco, John Yates Iii, Benjamin J Blencowe, Alan M Lambowitz, Paul Schimmel
Publisher Correction: Arg-tRNA synthetase links inflammatory metabolism to RNA splicing and nuclear trafficking via SRRM2. Nature cell biology (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Eva S Istvan, Francisco M Guerra, Matthew Abraham, Kuo-Sen Huang, Frances Rocamora, Haoshuang Zhao, Lan Xu, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Madeline R Luth, Haissi Cui, Tuo Yang, Sara Palomo Diaz, Maria G Gomez-Lorenzo, Tarrick Qahash, Nimisha Mittal, Sabine Ottilie, Jacquin C Niles, Marcus Chee San Lee, Manuel Llinás, Nobutaka Kato, John Okombo, David A Fidock, Paul Schimmel, Francisco Javier Gamo, Daniel E Goldberg, Elizabeth A Winzeler
Cytoplasmic isoleucyl tRNA synthetase as an attractive multistage antimalarial drug target. Science translational medicine 15 (686) (2023)
Lu Han, Zhiteng Luo, Yingchen Ju, Bingyi Chen, Taotao Zou, Jun-Jian Wang, Jun Xu, Qiong Gu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
The binding mode of orphan glycyl-tRNA synthetase with tRNA supports the synthetase classification and reveals large domain movements. Science advances 9 (6) (2023)
Bernhard Kuhle, Marscha Hirschi, Lili K Doerfel, Gabriel C Lander, Paul Schimmel
Structural basis for shape-selective recognition and aminoacylation of a D-armless human mitochondrial tRNA. Nature communications 13 (1) (2022)
Yingchen Ju, Lu Han, Bingyi Chen, Zhiteng Luo, Qiong Gu, Jun Xu, Xiang-Lei Yang, Paul Schimmel, Huihao Zhou
X-shaped structure of bacterial heterotetrameric tRNA synthetase suggests cryptic prokaryote functions and a rationale for synthetase classifications. Nucleic acids research 49 (17) (2021)