Jacek Jemielity

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 50

Top Venues

Journal of the American Chemical Society

Nucleic acids research

Chemistry (Weinheim an der Bergstrasse, Germany)

The Journal of organic chemistry

University of Warsaw

University of Warsaw (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Warsaw

Poland

Group Leader :: Centre of New Technologies

Education History

University of Warsaw

Poland

PHD :: Faculty of Chemistry

Publications

Piotr Surynt, Blazej A Wojtczak, Mikolaj Chrominski, Joanna Panecka-Hofman, Karina Kwapiszewska, Tomasz Kalwarczyk, Dorota Kubacka, Tomasz Spiewla, Renata Kasprzyk, Robert Holyst, Joanna Kowalska, Jacek Jemielity
Trimethylguanosine cap-fluorescent molecular rotor (TMG-FMR) conjugates are potent, specific snurportin1 ligands enabling visualization in living cells. Organic & biomolecular chemistry 22 (33) (2024)
Piotr Surynt, Blazej A Wojtczak, Mikolaj Chrominski, Joanna Panecka-Hofman, Karina Kwapiszewska, Tomasz Kalwarczyk, Dorota Kubacka, Tomasz Spiewla, Renata Kasprzyk, Robert Holyst, Joanna Kowalska, Jacek Jemielity
Trimethylguanosine cap-fluorescent molecular rotor (TMG-FMR) conjugates are potent, specific snurportin1 ligands enabling visualization in living cells. Organic & biomolecular chemistry 22 (33) (2024)
Marcin Warminski, Edyta Trepkowska, Miroslaw Smietanski, Pawel J Sikorski, Marek R Baranowski, Marcelina Bednarczyk, Hanna Kedzierska, Bartosz Majewski, Adam Mamot, Diana Papiernik, Agnieszka Popielec, Remigiusz A Serwa, Brittany A Shimanski, Piotr Sklepkiewicz, Marta Sklucka, Olga Sokolowska, Tomasz Spiewla, Diana Toczydlowska-Socha, Zofia Warminska, Karol Wolosewicz, Joanna Zuberek, Jeffrey S Mugridge, Dominika Nowis, Jakub Golab, Jacek Jemielity, Joanna Kowalska
Trinucleotide mRNA Cap Analogue N 6-Benzylated at the Site of Posttranscriptional m6 A m Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo. Journal of the American Chemical Society 146 (12) (2024)
Marcin Warminski, Edyta Trepkowska, Miroslaw Smietanski, Pawel J Sikorski, Marek R Baranowski, Marcelina Bednarczyk, Hanna Kedzierska, Bartosz Majewski, Adam Mamot, Diana Papiernik, Agnieszka Popielec, Remigiusz A Serwa, Brittany A Shimanski, Piotr Sklepkiewicz, Marta Sklucka, Olga Sokolowska, Tomasz Spiewla, Diana Toczydlowska-Socha, Zofia Warminska, Karol Wolosewicz, Joanna Zuberek, Jeffrey S Mugridge, Dominika Nowis, Jakub Golab, Jacek Jemielity, Joanna Kowalska
Trinucleotide mRNA Cap Analogue N 6-Benzylated at the Site of Posttranscriptional m6 A m Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo. Journal of the American Chemical Society 146 (12) (2024)
Marcin Warminski, Edyta Trepkowska, Miroslaw Smietanski, Pawel J Sikorski, Marek R Baranowski, Marcelina Bednarczyk, Hanna Kedzierska, Bartosz Majewski, Adam Mamot, Diana Papiernik, Agnieszka Popielec, Remigiusz A Serwa, Brittany A Shimanski, Piotr Sklepkiewicz, Marta Sklucka, Olga Sokolowska, Tomasz Spiewla, Diana Toczydlowska-Socha, Zofia Warminska, Karol Wolosewicz, Joanna Zuberek, Jeffrey S Mugridge, Dominika Nowis, Jakub Golab, Jacek Jemielity, Joanna Kowalska
Trinucleotide mRNA Cap Analogue N 6-Benzylated at the Site of Posttranscriptional m6 A m Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo. Journal of the American Chemical Society 146 (12) (2024)
Marcin Warminski, Edyta Trepkowska, Miroslaw Smietanski, Pawel J Sikorski, Marek R Baranowski, Marcelina Bednarczyk, Hanna Kedzierska, Bartosz Majewski, Adam Mamot, Diana Papiernik, Agnieszka Popielec, Remigiusz A Serwa, Brittany A Shimanski, Piotr Sklepkiewicz, Marta Sklucka, Olga Sokolowska, Tomasz Spiewla, Diana Toczydlowska-Socha, Zofia Warminska, Karol Wolosewicz, Joanna Zuberek, Jeffrey S Mugridge, Dominika Nowis, Jakub Golab, Jacek Jemielity, Joanna Kowalska
Trinucleotide mRNA Cap Analogue N 6-Benzylated at the Site of Posttranscriptional m6 A m Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo. Journal of the American Chemical Society (2024)
Marcin Warminski, Edyta Trepkowska, Miroslaw Smietanski, Pawel J Sikorski, Marek R Baranowski, Marcelina Bednarczyk, Hanna Kedzierska, Bartosz Majewski, Adam Mamot, Diana Papiernik, Agnieszka Popielec, Remigiusz A Serwa, Brittany A Shimanski, Piotr Sklepkiewicz, Marta Sklucka, Olga Sokolowska, Tomasz Spiewla, Diana Toczydlowska-Socha, Zofia Warminska, Karol Wolosewicz, Joanna Zuberek, Jeffrey S Mugridge, Dominika Nowis, Jakub Golab, Jacek Jemielity, Joanna Kowalska
Trinucleotide mRNA Cap Analogue N 6-Benzylated at the Site of Posttranscriptional m6 A m Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo. Journal of the American Chemical Society 146 (12) (2024)
Marcin Warminski, Anais Depaix, Kamil Ziemkiewicz, Tomasz Spiewla, Joanna Zuberek, Karolina Drazkowska, Hanna Kedzierska, Agnieszka Popielec, Marek R Baranowski, Marta Sklucka, Marcelina Bednarczyk, Miroslaw Smietanski, Karol Wolosewicz, Bartosz Majewski, Remigiusz A Serwa, Dominika Nowis, Jakub Golab, Joanna Kowalska, Jacek Jemielity
Trinucleotide cap analogs with triphosphate chain modifications: synthesis, properties, and evaluation as mRNA capping reagents. Nucleic acids research (2024)
Marcin Warminski, Katarzyna Grab, Kacper Szczepanski, Tomasz Spiewla, Joanna Zuberek, Joanna Kowalska, Jacek Jemielity
Photoactivatable mRNA 5' Cap Analogs for RNA-Protein Crosslinking. Advanced science (Weinheim, Baden-Wurttemberg, Germany) (2024)
Marcin Warminski, Edyta Trepkowska, Miroslaw Smietanski, Pawel J Sikorski, Marek R Baranowski, Marcelina Bednarczyk, Hanna Kedzierska, Bartosz Majewski, Adam Mamot, Diana Papiernik, Agnieszka Popielec, Remigiusz A Serwa, Brittany A Shimanski, Piotr Sklepkiewicz, Marta Sklucka, Olga Sokolowska, Tomasz Spiewla, Diana Toczydlowska-Socha, Zofia Warminska, Karol Wolosewicz, Joanna Zuberek, Jeffrey S Mugridge, Dominika Nowis, Jakub Golab, Jacek Jemielity, Joanna Kowalska
Trinucleotide mRNA Cap Analogue N 6-Benzylated at the Site of Posttranscriptional m6 A m Mark Facilitates mRNA Purification and Confers Superior Translational Properties In Vitro and In Vivo. Journal of the American Chemical Society 146 (12) (2024)
Piotr Surynt, Blazej A Wojtczak, Mikolaj Chrominski, Joanna Panecka-Hofman, Karina Kwapiszewska, Tomasz Kalwarczyk, Dorota Kubacka, Tomasz Spiewla, Renata Kasprzyk, Robert Holyst, Joanna Kowalska, Jacek Jemielity
Trimethylguanosine cap-fluorescent molecular rotor (TMG-FMR) conjugates are potent, specific snurportin1 ligands enabling visualization in living cells. Organic & biomolecular chemistry (2024)
Marcin Warminski, Adam Mamot, Anaïs Depaix, Joanna Kowalska, Jacek Jemielity
Chemical Modifications of mRNA Ends for Therapeutic Applications. Accounts of chemical research (2023)
Mateusz Kozarski, Karolina Drazkowska, Marcelina Bednarczyk, Marcin Warminski, Jacek Jemielity, Joanna Kowalska
Towards superior mRNA caps accessible by click chemistry: synthesis and translational properties of triazole-bearing oligonucleotide cap analogs. RSC advances 13 (19) (2023)
Hai-Jun Zhang, Michał Ociepa, Molhm Nassir, Bin Zheng, Sarah A Lewicki, Veronica Salmaso, Helay Baburi, Jessica Nagel, Salahuddin Mirza, Beatriz Bueschbell, Haneen Al-Hroub, Olga Perzanowska, Ziqing Lin, Michael A Schmidt, Martin D Eastgate, Kenneth A Jacobson, Christa Elisabeth Müller, Joanna Kowalska, Jacek Jemielity, Phil S Baran
Stereocontrolled access to thioisosteres of nucleoside di- and triphosphates. Nature chemistry (2023)
Blazej A Wojtczak, Marcelina Bednarczyk, Pawel J Sikorski, Anna Wojtczak, Piotr Surynt, Joanna Kowalska, Jacek Jemielity
Synthesis and Evaluation of Diguanosine Cap Analogs Modified at the C8-Position by Suzuki-Miyaura Cross-Coupling: Discovery of 7-Methylguanosine-Based Molecular Rotors. The Journal of organic chemistry (2023)
Mateusz Kozarski, Karolina Drazkowska, Marcelina Bednarczyk, Marcin Warminski, Jacek Jemielity, Joanna Kowalska
Towards superior mRNA caps accessible by click chemistry: synthesis and translational properties of triazole-bearing oligonucleotide cap analogs. RSC advances 13 (19) (2023)
Mateusz Kozarski, Karolina Drazkowska, Marcelina Bednarczyk, Marcin Warminski, Jacek Jemielity, Joanna Kowalska
Towards superior mRNA caps accessible by click chemistry: synthesis and translational properties of triazole-bearing oligonucleotide cap analogs. RSC advances 13 (19) (2023)
Marcelina Bednarczyk, Jessica K Peters, Renata Kasprzyk, Jagoda Starek, Marcin Warminski, Tomasz Spiewla, Jeffrey S Mugridge, John D Gross, Jacek Jemielity, Joanna Kowalska
Fluorescence-Based Activity Screening Assay Reveals Small Molecule Inhibitors of Vaccinia Virus mRNA Decapping Enzyme D9. ACS chemical biology 17 (6) (2022)
Mikołaj Chrominski, Kamil Ziemkiewicz, Joanna Kowalska, Jacek Jemielity
Introducing SuFNucs: Sulfamoyl-Fluoride-Functionalized Nucleosides That Undergo Sulfur Fluoride Exchange Reaction. Organic letters 24 (27) (2022)
Anna Pepanian, Paul Sommerfeld, Renata Kasprzyk, Toni Kühl, F Ayberk Binbay, Christoph Hauser, Reik Löser, Robert Wodtke, Marcelina Bednarczyk, Mikolaj Chrominski, Joanna Kowalska, Jacek Jemielity, Diana Imhof, Markus Pietsch
Fluorescence Anisotropy Assay with Guanine Nucleotides Provides Access to Functional Analysis of Gαi1 Proteins. Analytical chemistry 94 (41) (2022)
Kamil Ziemkiewicz, Marcin Warminski, Radoslaw Wojcik, Joanna Kowalska, Jacek Jemielity
Quick Access to Nucleobase-Modified Phosphoramidites for the Synthesis of Oligoribonucleotides Containing Post-Transcriptional Modifications and Epitranscriptomic Marks. The Journal of organic chemistry 87 (15) (2022)
Karolina Drazkowska, Rafal Tomecki, Marcin Warminski, Natalia Baran, Dominik Cysewski, Anaïs Depaix, Renata Kasprzyk, Joanna Kowalska, Jacek Jemielity, Pawel J Sikorski
2'-O-Methylation of the second transcribed nucleotide within the mRNA 5' cap impacts the protein production level in a cell-specific manner and contributes to RNA immune evasion. Nucleic acids research 50 (16) (2022)
Agnieszka Mlynarska-Cieslak, Mikolaj Chrominski, Tomasz Spiewla, Marek R Baranowski, Marcelina Bednarczyk, Jacek Jemielity, Joanna Kowalska
Fluorinated Phosphoadenosine 5'-Phosphosulfate Analogues for Continuous Sulfotransferase Activity Monitoring and Inhibitor Screening by 19 F NMR Spectroscopy. ACS chemical biology 17 (3) (2022)
Olga Perzanowska, Miroslaw Smietanski, Jacek Jemielity, Joanna Kowalska
Chemically Modified Poly(A) Analogs Targeting PABP: Structure Activity Relationship and Translation Inhibitory Properties. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (42) (2022)
Dorota Kubacka, Mateusz Kozarski, Marek R Baranowski, Radoslaw Wojcik, Joanna Panecka-Hofman, Dominika Strzelecka, Jerome Basquin, Jacek Jemielity, Joanna Kowalska
Substrate-Based Design of Cytosolic Nucleotidase IIIB Inhibitors and Structural Insights into Inhibition Mechanism. Pharmaceuticals (Basel, Switzerland) 15 (5) (2022)
Piotr Rzymski, Leszek Borkowski, Marcin Drąg, Robert Flisiak, Jacek Jemielity, Jacek Krajewski, Agnieszka Mastalerz-Migas, Andrzej Matyja, Krzysztof Pyrc, Krzysztof Simon, Michał Sutkowski, Jacek Wysocki, Joanna Zajkowska, Andrzej Fal
The Strategies to Support the COVID-19 Vaccination with Evidence-Based Communication and Tackling Misinformation. Vaccines 9 (2) (2021)
Anna Wojtczak, Renata Kasprzyk, Marcin Warminski, Krystian Ubych, Dorota Kubacka, Pawel J Sikorski, Jacek Jemielity, Joanna Kowalska
Evaluation of carboxyfluorescein-labeled 7-methylguanine nucleotides as probes for studying cap-binding proteins by fluorescence anisotropy. Scientific reports 11 (1) (2021)
Anaïs Depaix, Agnieszka Mlynarska-Cieslak, Marcin Warminski, Pawel J Sikorski, Jacek Jemielity, Joanna Kowalska
RNA Ligation for Mono and Dually Labeled RNAs. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (47) (2021)
Alison Galloway, Aneesa Kaskar, Dimitrinka Ditsova, Abdelmadjid Atrih, Harunori Yoshikawa, Carolina Gomez-Moreira, Olga Suska, Marcin Warminski, Renata Grzela, Angus I Lamond, Edward Darzynkiewicz, Jacek Jemielity, Victoria H Cowling
Upregulation of RNA cap methyltransferase RNMT drives ribosome biogenesis during T cell activation. Nucleic acids research 49 (12) (2021)
Adam Mamot, Pawel J Sikorski, Aleksandra Siekierska, Peter de Witte, Joanna Kowalska, Jacek Jemielity
Ethylenediamine derivatives efficiently react with oxidized RNA 3' ends providing access to mono and dually labelled RNA probes for enzymatic assays and in vivo translation. Nucleic acids research (2021)
Ryan W Tibble, Anaïs Depaix, Joanna Kowalska, Jacek Jemielity, John D Gross
Biomolecular condensates amplify mRNA decapping by biasing enzyme conformation. Nature chemical biology 17 (5) (2021)
Radoslaw Wojcik, Marek R Baranowski, Lukasz Markiewicz, Dorota Kubacka, Marcelina Bednarczyk, Natalia Baran, Anna Wojtczak, Pawel J Sikorski, Joanna Zuberek, Joanna Kowalska, Jacek Jemielity
Novel N7-Arylmethyl Substituted Dinucleotide mRNA 5' cap Analogs: Synthesis and Evaluation as Modulators of Translation. Pharmaceutics 13 (11) (2021)
Renata Kasprzyk, Jacek Jemielity
Enzymatic Assays to Explore Viral mRNA Capping Machinery. Chembiochem : a European journal of chemical biology 22 (23) (2021)
Natalia Kleczewska, Pawel J Sikorski, Zofia Warminska, Lukasz Markiewicz, Renata Kasprzyk, Natalia Baran, Karina Kwapiszewska, Aneta Karpińska, Jaroslaw Michalski, Robert Holyst, Joanna Kowalska, Jacek Jemielity
Cellular delivery of dinucleotides by conjugation with small molecules: targeting translation initiation for anticancer applications. Chemical science 12 (30) (2021)
Marcin Warminski, Joanna Kowalska, Elzbieta Nowak, Dorota Kubacka, Ryan Tibble, Renata Kasprzyk, Pawel J Sikorski, John D Gross, Marcin Nowotny, Jacek Jemielity
Structural Insights into the Interaction of Clinically Relevant Phosphorothioate mRNA Cap Analogs with Translation Initiation Factor 4E Reveal Stabilization via Electrostatic Thio-Effect. ACS chemical biology 16 (2) (2021)
Dominika Strzelecka, Miroslaw Smietanski, Pawel J Sikorski, Marcin Warminski, Joanna Kowalska, Jacek Jemielity
Phosphodiester modifications in mRNA poly(A) tail prevent deadenylation without compromising protein expression. RNA (New York, N.Y.) 26 (12) (2020)
Renata Kasprzyk, Mateusz Fido, Adam Mamot, Przemyslaw Wanat, Miroslaw Smietanski, Michal Kopcial, Victoria H Cowling, Joanna Kowalska, Jacek Jemielity
Direct High-Throughput Screening Assay for mRNA Cap Guanine-N7 Methyltransferase Activity. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (49) (2020)
Mikolaj Chrominski, Marek R Baranowski, Sebastian Chmielinski, Joanna Kowalska, Jacek Jemielity
Synthesis of Trifluoromethylated Purine Ribonucleotides and Their Evaluation as 19F NMR Probes. The Journal of organic chemistry 85 (5) (2020)
Beata Miedziak, Anna Dobieżyńska, Zbigniew M Darżynkiewicz, Julia Bartkowska, Joanna Miszkiewicz, Joanna Kowalska, Marcin Warminski, Michal Tyras, Joanna Trylska, Jacek Jemielity, Edward Darzynkiewicz, Renata Grzela
Kinetic analysis of IFIT1 and IFIT5 interactions with different native and engineered RNAs and its consequences for designing mRNA-based therapeutics. RNA (New York, N.Y.) 26 (1) (2019)
Renata Kasprzyk, Beata J Starek, Sylwia Ciechanowicz, Dorota Kubacka, Joanna Kowalska, Jacek Jemielity
Fluorescent Turn-On Probes for the Development of Binding and Hydrolytic Activity Assays for mRNA Cap-Recognizing Proteins. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (27) (2019)
Michal Kopcial, Błażej A Wojtczak, Renata Kasprzyk, Joanna Kowalska, Jacek Jemielity
N1-Propargylguanosine Modified mRNA Cap Analogs: Synthesis, Reactivity, and Applications to the Study of Cap-Binding Proteins. Molecules (Basel, Switzerland) 24 (10) (2019)
Blazej A Wojtczak, Pawel J Sikorski, Kaja Fac-Dabrowska, Anna Nowicka, Marcin Warminski, Dorota Kubacka, Elzbieta Nowak, Marcin Nowotny, Joanna Kowalska, Jacek Jemielity
5'-Phosphorothiolate Dinucleotide Cap Analogues: Reagents for Messenger RNA Modification and Potent Small-Molecular Inhibitors of Decapping Enzymes. Journal of the American Chemical Society 140 (18) (2018)
Agnieszka Mlynarska-Cieslak, Anais Depaix, Ewa Grudzien-Nogalska, Pawel J Sikorski, Marcin Warminski, Megerditch Kiledjian, Jacek Jemielity, Joanna Kowalska
Nicotinamide-Containing Di- and Trinucleotides as Chemical Tools for Studies of NAD-Capped RNAs. Organic letters 20 (23) (2018)
Sylwia Bednarek, Vanesa Madan, Pawel J Sikorski, Ralf F W Bartenschlager, Joanna Kowalska, Jacek Jemielity
mRNAs biotinylated within the 5' cap and protected against decapping: new tools to capture RNA-protein complexes. Philosophical transactions of the Royal Society of London. Series B, Biological sciences 373 (1762) (2018)
Marcin Warminski, Pawel J Sikorski, Joanna Kowalska, Jacek Jemielity
Applications of Phosphate Modification and Labeling to Study (m)RNA Caps. Topics in current chemistry (Cham) 375 (1) (2017)
Marcin Warminski, Joanna Kowalska, Jacek Jemielity
Synthesis of RNA 5'-Azides from 2'-O-Pivaloyloxymethyl-Protected RNAs and Their Reactivity in Azide-Alkyne Cycloaddition Reactions. Organic letters 19 (13) (2017)
Adam Mamot, Pawel J Sikorski, Marcin Warminski, Joanna Kowalska, Jacek Jemielity
Azido-Functionalized 5' Cap Analogues for the Preparation of Translationally Active mRNAs Suitable for Fluorescent Labeling in Living Cells. Angewandte Chemie (International ed. in English) 56 (49) (2017)
Marcin Warminski, Pawel J Sikorski, Zofia Warminska, Maciej Lukaszewicz, Anna Kropiwnicka, Joanna Zuberek, Edward Darzynkiewicz, Joanna Kowalska, Jacek Jemielity
Amino-Functionalized 5' Cap Analogs as Tools for Site-Specific Sequence-Independent Labeling of mRNA. Bioconjugate chemistry 28 (7) (2017)
Marcin Ziemniak, Jeffrey S Mugridge, Joanna Kowalska, Robert E Rhoads, John D Gross, Jacek Jemielity
Two-headed tetraphosphate cap analogs are inhibitors of the Dcp1/2 RNA decapping complex. RNA (New York, N.Y.) 22 (4) (2016)
Sylwia Walczak, Anna Nowicka, Dorota Kubacka, Kaja Fac, Przemyslaw Wanat, Seweryn Mroczek, Joanna Kowalska, Jacek Jemielity
A novel route for preparing 5' cap mimics and capped RNAs: phosphate-modified cap analogues obtained via click chemistry. Chemical science 8 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jacek Jemielity