James A Roper (J A Roper)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 13

Top Topics

Epithelial Mesenchymal Transition

Idiopathic Pulmonary Fibrosis

High Throughput

Top Venues

International journal of molecular sciences

Journal of medicinal chemistry

Nature reviews. Drug discovery

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Fredrik R Zetterberg, Kristoffer Peterson, Ulf J Nilsson, Kajsa Andréasson Dahlgren, Carl Diehl, Ian Holyer, Maria Håkansson, Areej Khabut, Barbro Kahl-Knutson, Hakon Leffler, Alison C MacKinnon, James A Roper, Robert J Slack, Reihaneh Zarrizi, Anders Pedersen
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer. Journal of medicinal chemistry 67 (11) (2024)
Henry Kim, Louis Kretz, Céline Ronin, Christina Starck, James A Roper, Barbro Kahl-Knutson, Kristoffer Peterson, Hakon Leffler, Ulf J Nilsson, Anders Pedersen, Fredrik R Zetterberg, Robert J Slack
Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance. International journal of molecular sciences 25 (12) (2024)
Henry Kim, Louis Kretz, Céline Ronin, Christina Starck, James A Roper, Barbro Kahl-Knutson, Kristoffer Peterson, Hakon Leffler, Ulf J Nilsson, Anders Pedersen, Fredrik R Zetterberg, Robert J Slack
Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance. International journal of molecular sciences 25 (12) (2024)
Henry Kim, Louis Kretz, Céline Ronin, Christina Starck, James A Roper, Barbro Kahl-Knutson, Kristoffer Peterson, Hakon Leffler, Ulf J Nilsson, Anders Pedersen, Fredrik R Zetterberg, Robert J Slack
Determining the Affinity and Kinetics of Small Molecule Inhibitors of Galectin-1 Using Surface Plasmon Resonance. International journal of molecular sciences 25 (12) (2024)
Rhianna Gasson, James A Roper, Robert J Slack
A Quantitative Human Red Blood Cell Agglutination Assay for Characterisation of Galectin Inhibitors. International journal of molecular sciences 25 (12) (2024)
Rhianna Gasson, James A Roper, Robert J Slack
A Quantitative Human Red Blood Cell Agglutination Assay for Characterisation of Galectin Inhibitors. International journal of molecular sciences 25 (12) (2024)
Rhianna Gasson, James A Roper, Robert J Slack
A Quantitative Human Red Blood Cell Agglutination Assay for Characterisation of Galectin Inhibitors. International journal of molecular sciences 25 (12) (2024)
Fredrik R Zetterberg, Kristoffer Peterson, Ulf J Nilsson, Kajsa Andréasson Dahlgren, Carl Diehl, Ian Holyer, Maria Håkansson, Areej Khabut, Barbro Kahl-Knutson, Hakon Leffler, Alison C MacKinnon, James A Roper, Robert J Slack, Reihaneh Zarrizi, Anders Pedersen
Discovery of the Selective and Orally Available Galectin-1 Inhibitor GB1908 as a Potential Treatment for Lung Cancer. Journal of medicinal chemistry (2024)
Fredrik R Zetterberg, Carl Diehl, Maria Håkansson, Barbro Kahl-Knutson, Hakon Leffler, Ulf J Nilsson, Kristoffer Peterson, James A Roper, Robert J Slack
Discovery of Selective and Orally Available Galectin-1 Inhibitors. Journal of medicinal chemistry (2023)
Fredrik R Zetterberg, Alison MacKinnon, Thomas Brimert, Lise Gravelle, Richard E Johnsson, Barbro Kahl-Knutson, Hakon Leffler, Ulf J Nilsson, Anders Pedersen, Kristoffer Peterson, James A Roper, Hans Schambye, Robert J Slack, Susan Tantawi
Discovery and Optimization of the First Highly Effective and Orally Available Galectin-3 Inhibitors for Treatment of Fibrotic Disease. Journal of medicinal chemistry 65 (19) (2022)
R J Slack, Simon J F Macdonald, James A Roper, R Gisli Jenkins, Richard J D Hatley
Emerging therapeutic opportunities for integrin inhibitors. Nature reviews. Drug discovery (2021)
Alison E John, Rebecca H Graves, K Tao Pun, Giovanni Vitulli, Ellen J Forty, Paul F Mercer, Josie L Morrell, John W Barrett, Rebecca F Rogers, Maryam Hafeji, Lloyd I Bibby, Elaine Gower, Valerie S Morrison, Yim Man, James A Roper, Jeni C Luckett, Lee A Borthwick, Ben S Barksby, Rachel A Burgoyne, Rory Barnes, Joelle Le, David J Flint, Susan Pyne, Anthony Habgood, Louise A Organ, Chitra Joseph, Rochelle C Edwards-Pritchard, Toby M Maher, Andrew J Fisher, Natasja Stæhr Gudmann, Diana J Leeming, Rachel Clare Chambers, Pauline T Lukey, Richard P Marshall, Simon J F Macdonald, R Gisli Jenkins, Robert J Slack
Translational pharmacology of an inhaled small molecule αvβ6 integrin inhibitor for idiopathic pulmonary fibrosis. Nature communications 11 (1) (2020)
James A Roper, Alex L Wilkinson, Elaine Gower, Robert J Slack
Downregulation of the αvβ6 Integrin via RGD Engagement Is Affinity and Time Dependent. The Journal of pharmacology and experimental therapeutics 376 (2) (2020)