James M Fleckenstein (J M Fleckenstein, James Fleckenstein)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 22

Top Venues

Infection and immunity

bioRxiv : the preprint server for biology

PLoS neglected tropical diseases

Proceedings of the National Academy of Sciences of the United States of America

Washington University in Saint Louis School of Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Washington University in Saint Louis School of Medicine

United States

Professor of Medicine and Molecular Microbiology :: Medicine

Washington University in Saint Louis School of Medicine Dec 01 2011 - Jun 01 2018

United States

Associate Professor :: Medicine

Publications

Zachary T Berndsen, Marjahan Akhtar, Mahima Thapa, Tim J Vickers, Aaron J Schmitz, Jonathan L Torre, Sabyasachi Baboo, Pardeep Kumar, Nazia Khatoon, Alaullah Sheikh, Melissa F Hamrick, Jolene K Diedrich, Salvador Martinez de Bartolome, Patrick T Garrett, John Yates Iii, Jackson S Turner, Renee M Laird, Frédéric M Poly, Chad K Porter, Jeffrey Copps, Ali H Ellebedy, Andrew B Ward, James M Fleckenstein
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin . bioRxiv : the preprint server for biology (2024)
Zachary T Berndsen, Marjahan Akhtar, Mahima Thapa, Tim J Vickers, Aaron J Schmitz, Jonathan L Torre, Sabyasachi Baboo, Pardeep Kumar, Nazia Khatoon, Alaullah Sheikh, Melissa F Hamrick, Jolene K Diedrich, Salvador Martinez de Bartolome, Patrick T Garrett, John Yates Iii, Jackson S Turner, Renee M Laird, Frédéric M Poly, Chad K Porter, Jeffrey Copps, Ali H Ellebedy, Andrew B Ward, James M Fleckenstein
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin . bioRxiv : the preprint server for biology (2024)
Alaullah Sheikh, Debayan Ganguli, Tim J Vickers, Bernhard B Singer, Jennifer D Foulke-Abel, Marjahan Akhtar, Nazia Khatoon, Bipul Setu, Supratim Basu, Clayton Harro, Nicole Maier, Wandy L Beatty, Subhra Chakraborty, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Mark Donowitz, James M Fleckenstein
Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization. bioRxiv : the preprint server for biology (2024)
Zachary T Berndsen, Marjahan Akhtar, Mahima Thapa, Tim J Vickers, Aaron Schmitz, Jonathan L Torres, Sabyasachi Baboo, Pardeep Kumar, Nazia Khatoon, Alaullah Sheikh, Melissa Hamrick, Jolene K Diedrich, Salvador Martinez-Bartolome, Patrick T Garrett, John R Yates, Jackson S Turner, Renee M Laird, Frédéric Poly, Chad K Porter, Jeffrey Copps, Ali H Ellebedy, Andrew B Ward, James M Fleckenstein
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin. PLoS pathogens 20 (9) (2024)
Alaullah Sheikh, Debayan Ganguli, Tim J Vickers, Bernhard B Singer, Jennifer D Foulke-Abel, Marjahan Akhtar, Nazia Khatoon, Bipul Setu, Supratim Basu, Clayton Harro, Nicole Maier, Wandy L Beatty, Subhra Chakraborty, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Mark Donowitz, James M Fleckenstein
Host-derived CEACAM-laden vesicles engage enterotoxigenic Escherichia coli for elimination and toxin neutralization. Proceedings of the National Academy of Sciences of the United States of America 121 (38) (2024)
Alaullah Sheikh, Debayan Ganguli, Tim J Vickers, Bernhard B Singer, Jennifer D Foulke-Abel, Marjahan Akhtar, Nazia Khatoon, Bipul Setu, Supratim Basu, Clayton Harro, Nicole Maier, Wandy L Beatty, Subhra Chakraborty, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Mark Donowitz, James M Fleckenstein
Host-derived CEACAM-laden vesicles engage enterotoxigenic E. coli for elimination and toxin neutralization. bioRxiv : the preprint server for biology (2024)
Zachary T Berndsen, Marjahan Akhtar, Mahima Thapa, Tim J Vickers, Aaron J Schmitz, Jonathan L Torre, Sabyasachi Baboo, Pardeep Kumar, Nazia Khatoon, Alaullah Sheikh, Melissa F Hamrick, Jolene K Diedrich, Salvador Martinez de Bartolome, Patrick T Garrett, John Yates Iii, Jackson S Turner, Renee M Laird, Frédéric M Poly, Chad K Porter, Jeffrey Copps, Ali H Ellebedy, Andrew B Ward, James M Fleckenstein
Repeat modules and N-linked glycans define structure and antigenicity of a critical enterotoxigenic E. coli adhesin . bioRxiv : the preprint server for biology (2024)
Clifford Manyo Ntui, James M Fleckenstein, Wolf-Dieter Schubert
Structural and biophysical characterization of the secreted, β-helical adhesin EtpA of Enterotoxigenic Escherichia coli. PloS one 18 (6) (2023)
Alaullah Sheikh, Brunda Tumala, Tim J Vickers, John C Martin, Bruce A Rosa, Subrata Sabui, Supratim Basu, Rita D Simoes, Makedonka Mitreva, Chad Storer, Eric Tycksen, Richard D Head, Wandy Beatty, Hamid M Said, James M Fleckenstein
Enterotoxigenic Escherichia coli heat-labile toxin drives enteropathic changes in small intestinal epithelia. Nature communications 13 (1) (2022)
Alaullah Sheikh, Tamding Wangdi, Tim J Vickers, Bailey Aaron, Margot Palmer, Mark J Miller, Seonyoung Kim, Cassandra Herring, Rita Simoes, Jennifer A Crainic, Jeffrey C Gildersleeve, Sjoerd van der Post, Gunnar C Hansson, James M Fleckenstein
Enterotoxigenic Escherichia coli degrades the host MUC2 mucin barrier to facilitate critical pathogen-enterocyte interactions in human small intestine. Infection and immunity (2021)
F Matthew Kuhlmann, R O Laine, S Afrin, Rie Nakajima, M Akhtar, T Vickers, K Parker, N N Nizam, V Grigura, C W Goss, P L Felgner, David A Rasko, Firdausi Qadri, James M Fleckenstein
Contribution of Noncanonical Antigens to Virulence and Adaptive Immunity in Human Infection with Enterotoxigenic E. coli. Infection and immunity 89 (5) (2021)
Eric Cox, Meryem Aloulou, James M Fleckenstein, Christina Schäffer, Åsa Sjöling, Stephanie Schüller, Kurt Hanevik, Bert Devriendt, Weiping Zhang, Ann-Mari Svennerholm, Edward G Dudley
The Intriguing Interaction of Escherichia coli with the Host Environment and Innovative Strategies To Interfere with Colonization: a Summary of the 2019 E. coli and the Mucosal Immune System Meeting. Applied and environmental microbiology 86 (24) (2020)
Alaullah Sheikh, Brunda Tumala, Tim J Vickers, David M Alvarado, Matthew A Ciorba, Taufiqur Rahman Bhuiyan, Firdausi Qadri, Bernhard B Singer, James M Fleckenstein
CEACAMs serve as toxin-stimulated receptors for enterotoxigenic Escherichia coli. Proceedings of the National Academy of Sciences of the United States of America 117 (46) (2020)
Jennifer D Foulke-Abel, Huimin Yu, Laxmi Sunuwar, Ruxian Lin, James M Fleckenstein, James B Kaper, Mark Donowitz
Phosphodiesterase 5 (PDE5) restricts intracellular cGMP accumulation during enterotoxigenic Escherichia coli infection. Gut microbes 12 (1) (2020)
Laxmi Sunuwar, Jianyi Yin, Magdalena Kasendra, Katia Karalis, James Kaper, James M Fleckenstein, Mark Donowitz
Mechanical Stimuli Affect Escherichia coli Heat-Stable Enterotoxin-Cyclic GMP Signaling in a Human Enteroid Intestine-Chip Model. Infection and immunity 88 (3) (2020)
F Matthew Kuhlmann, John Martin, Tracy H Hazen, Tim J Vickers, Madeline Pashos, Pablo C Okhuysen, Oscar G Gómez-Duarte, Elizabeth Cebelinski, Dave Boxrud, Felipe Del Canto, Roberto Vidal, Firdausi Qadri, Makedonka Mitreva, David A Rasko, James M Fleckenstein
Conservation and global distribution of non-canonical antigens in Enterotoxigenic Escherichia coli. PLoS neglected tropical diseases 13 (11) (2019)
Subhra Chakraborty, Arlo Randall, Tim J Vickers, Doug Molina, Clayton D Harro, Barbara DeNearing, Jessica Brubaker, David A Sack, A Louis Bourgeois, Philip L Felgner, Xiaowu Liang, Sachin Mani, Heather Wenzel, R Reid Townsend, Petra E Gilmore, Michael J Darsley, David A Rasko, James M Fleckenstein
Interrogation of a live-attenuated enterotoxigenic Escherichia coli vaccine highlights features unique to wild-type infection. NPJ vaccines 4 (2019)
David A Rasko, Felipe Del Canto, Qingwei Luo, James M Fleckenstein, Roberto Vidal, Tracy H Hazen
Comparative genomic analysis and molecular examination of the diversity of enterotoxigenic Escherichia coli isolates from Chile. PLoS neglected tropical diseases 13 (11) (2019)
Yuehui Zhu, Qingwei Luo, Sierra M Davis, Chase Westra, Tim J Vickers, James M Fleckenstein
Molecular Determinants of Enterotoxigenic Escherichia coli Heat-Stable Toxin Secretion and Delivery. Infection and immunity 86 (11) (2018)
Alaullah Sheikh, Rasheduzzaman Rashu, Yasmin Ara Begum, F Matthew Kuhlmann, Matthew A Ciorba, Scott J Hultgren, Firdausi Qadri, James M Fleckenstein
Highly conserved type 1 pili promote enterotoxigenic E. coli pathogen-host interactions. PLoS neglected tropical diseases 11 (5) (2017)
Qingwei Luo, Tim J Vickers, James M Fleckenstein
Immunogenicity and Protective Efficacy against Enterotoxigenic Escherichia coli Colonization following Intradermal, Sublingual, or Oral Vaccination with EtpA Adhesin. Clinical and vaccine immunology : CVI 23 (7) (2016)
Pardeep Kumar, F Matthew Kuhlmann, Kirandeep Bhullar, Hyungjun Yang, Bruce A Vallance, Lijun Xia, Qingwei Luo, James M Fleckenstein
Dynamic Interactions of a Conserved Enterotoxigenic Escherichia coli Adhesin with Intestinal Mucins Govern Epithelium Engagement and Toxin Delivery. Infection and immunity 84 (12) (2016)

James M Fleckenstein.css-eqlu8i{font-size:small;padding-left:4px;} (J M Fleckenstein, James Fleckenstein)

Publication Activity (10 Years)

Top Topics

Top Venues

James M Fleckenstein (J M Fleckenstein, James Fleckenstein)