James McCluskey (J McCluskey)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2023
Publications (10 Years): 32

Top Venues

Nature communications

Journal of immunology (Baltimore, Md. : 1950)

Nature immunology

Science immunology

The University of Melbourne

This page only lists publications with an associated author ORCID identifier.

Affiliation History

The University of Melbourne Mar 26 2011

Australia

Deputy Vice Chancellor Research :: Chancellery Research

The University of Melbourne Jan 01 1997

Australia

Chair in Microbiology and Immunology, Redmond Barry Distinguished Professor :: Microbiology and Immunology, Peter Doherty Institute for Infection and Immunity

Publications

Nicole A Mifsud, Patricia T Illing, Rebecca Ho, Johanna E E Tuomisto, Heidi Fettke, Kerry A Mullan, James McCluskey, Jamie Rossjohn, Julian P Vivian, Rangsima Reantragoon, Anthony Wayne Purcell
The allopurinol metabolite, oxypurinol, drives oligoclonal expansions of drug-reactive T cells in resolved hypersensitivity cases and drug-naïve healthy donors. Allergy (2023)
Lauren J Howson, Wael Awad, Anouk von Borstel, Hui Jing Lim, Hamish E G McWilliam, Maria L Sandoval-Romero, Shamik Majumdar, Abdul Rezzak Hamzeh, T Daniel Andrews, David H McDermott, Philip M Murphy, Jérôme Le Nours, Jeffrey Y W Mak, Ligong Liu, David P Fairlie, James McCluskey, Jose A Villadangos, Matthew C Cook, Stephen J Turner, Martin S Davey, Samar Ojaimi, Jamie Rossjohn
Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1. Science immunology 5 (49) (2022)
Sara A Suliman, Lars Kjer-Nielsen, Sarah K Iwany, Kattya Lopez Tamara, Liyen Loh, Ludivine Grzelak, Katherine Kedzierska, Tonatiuh A Ocampo, Alexandra J Corbett, James McCluskey, Jamie Rossjohn, Segundo Ramos Leon, Roger I Calderon, Leonid Lecca-Garcia, Megan B Murray, D Branch Moody, Ildiko Van Rhijn
Dual TCR-α Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation. Journal of immunology (Baltimore, Md. : 1950) 208 (6) (2022)
Michael N T Souter, Wael Awad, Shihan Li, Troi J Pediongco, Bronwyn S Meehan, Lucy J Meehan, Zehua Tian, Zhe Zhao, Huimeng Wang, Adam Nelson, Jérôme Le Nours, Yogesh B Khandokar, T Praveena, Jacinta Wubben, Jie Lin, Lucy C Sullivan, George O Lovrecz, Jeffrey Y W Mak, Ligong Liu, Lyudmila Kostenko, Katherine Kedzierska, Alexandra J Corbett, David P Fairlie, Andrew G Brooks, Nicholas A Gherardin, Adam P Uldrich, Zhenjun Chen, Jamie Rossjohn, Dale I Godfrey, James McCluskey, Daniel G Pellicci, Sidonia Barbara Guiomar Eckle
CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. The Journal of experimental medicine 219 (9) (2022)
Emma V Petley, Hui-Fern Koay, Melissa A Henderson, Kevin Sek, Kirsten L Todd, Simon P Keam, Junyun Lai, Imran G House, Jasmine Li, Magnus Zethoven, Amanda X Y Chen, Amanda J Oliver, Jessica Michie, Andrew J Freeman, Lauren Giuffrida, Jack D Chan, Angela Pizzolla, Jeffrey Y W Mak, Timothy R McCulloch, Fernando Souza-Fonseca-Guimaraes, Conor J Kearney, Rosemary Millen, Robert G Ramsay, Nicholas D Huntington, James McCluskey, Jane Oliaro, David P Fairlie, Paul Joseph Neeson, Dale I Godfrey, Paul A Beavis, Phillip K Darcy
MAIT cells regulate NK cell-mediated tumor immunity. Nature communications 12 (1) (2021)
Zhongfang Wang, Xiaoyun Yang, Jiaying Zhong, Yumin Zhou, Zhiqiang Tang, Haibo Zhou, Jun He, Xinyue Mei, Yonghong Tang, Bijia Lin, Zhenjun Chen, James McCluskey, Ji Yang, Alexandra J Corbett, Pixin Ran
Exposure to SARS-CoV-2 generates T-cell memory in the absence of a detectable viral infection. Nature communications 12 (1) (2021)
Lauren J Howson, Jasmine Li, Anouk von Borstel, Adele Barugahare, Jeffrey Y W Mak, David P Fairlie, James McCluskey, Stephen J Turner, Martin S Davey, Jamie Rossjohn
Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate. Journal of immunology (Baltimore, Md. : 1950) 206 (7) (2021)
Zhe Zhao, Huimeng Wang, Mai Shi, Tianyuan Zhu, Troi Pediongco, Xin Yi Lim, Bronwyn S Meehan, Adam G Nelson, David P Fairlie, Jeffrey Y W Mak, Sidonia Barbara Guiomar Eckle, Marcela L Moreira, Carolin Tumpach, Michael Bramhall, Cameron G Williams, Hyun Jae Lee, Ashraful Haque, Maximilien Evrard, Jamie Rossjohn, James McCluskey, Alexandra J Corbett, Zhenjun Chen
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection. Nature communications 12 (1) (2021)
Liyen Loh, Nicholas A Gherardin, Sneha Sant, Ludivine Grzelak, Jeremy Chase Crawford, Nicola L Bird, Hui-Fern Koay, Carolien E van de Sandt, Marcela L Moreira, Martha Lappas, E Kaitlynn Allen, Jane Crowe, Thomas Loudovaris, Katie L Flanagan, Kylie M Quinn, Jamie Rossjohn, Paul Glyndwr Thomas, Sidonia Barbara Guiomar Eckle, James McCluskey, Dale I Godfrey, Katherine Kedzierska
Human Mucosal-Associated Invariant T Cells in Older Individuals Display Expanded TCRαβ Clonotypes with Potent Antimicrobial Responses. Journal of immunology (Baltimore, Md. : 1950) 204 (5) (2020)
Wael Awad, Geraldine J M Ler, Weijun Xu, Andrew N Keller, Jeffrey Y W Mak, Xin Yi Lim, Ligong Liu, Sidonia Barbara Guiomar Eckle, Jérôme Le Nours, James McCluskey, Alexandra J Corbett, David P Fairlie, Jamie Rossjohn
The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature immunology 21 (4) (2020)
Marcela L Moreira, Michael N T Souter, Zhenjun Chen, Liyen Loh, James McCluskey, Daniel G Pellicci, Sidonia Barbara Guiomar Eckle
Hypersensitivities following allergen antigen recognition by unconventional T cells. Allergy 75 (10) (2020)
Hui-Fern Koay, S Su, Daniela Amann-Zalcenstein, Stephen R Daley, Iain Comerford, L Miosge, Carly E Whyte, I E Konstantinov, Y d'Udekem, T Baldwin, Peter F Hickey, S P Berzins, Jeffrey Y W Mak, Yovina Sontani, C M Roots, T Sidwell, A Kallies, Zhenjun Chen, Simone Nüssing, Katherine Kedzierska, Laura K Mackay, Shaun R McColl, Elissa K Deenick, David P Fairlie, James McCluskey, Christopher C Goodnow, M E Ritchie, Gabrielle T Belz, Shalin H Naik, Daniel G Pellicci, Dale I Godfrey
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science immunology 4 (41) (2020)
Hamish E G McWilliam, Jeffrey Y W Mak, Wael Awad, Matthew Zorkau, Sebastian Cruz-Gomez, Hui Jing Lim, Yuting Yan, Sam Wormald, Laura F Dagley, Sidonia Barbara Guiomar Eckle, Alexandra J Corbett, Haiyin Liu, Shihan Li, Scott J J Reddiex, Justine D Mintern, Ligong Liu, James McCluskey, Jamie Rossjohn, David P Fairlie, Jose A Villadangos
Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. Proceedings of the National Academy of Sciences of the United States of America 117 (40) (2020)
Amine Toubal, Badr Kiaf, Lucie Beaudoin, Lucie Cagninacci, Moez Rhimi, Blandine Fruchet, Jennifer da Silva, Alexandra J Corbett, Yannick Simoni, Olivier Lantz, Jamie Rossjohn, James McCluskey, Philippe Lesnik, Emmanuelle Maguin, Agnès Lehuen
Mucosal-associated invariant T cells promote inflammation and intestinal dysbiosis leading to metabolic dysfunction during obesity. Nature communications 11 (1) (2020)
Steven C Neier, Alejandro Ferrer, Katelynn M Wilton, Stephen E P Smith, April Huseby Kelcher, Kevin D Pavelko, Jenna M Canfield, Tessa R Davis, Robert J Stiles, Zhenjun Chen, James McCluskey, Scott R Burrows, Jamie Rossjohn, Deanne M Hebrink, Eva M Carmona, Andrew H Limper, Dietmar J Kappes, Peter J Wettstein, Aaron J Johnson, Larry R Pease, Mark A Daniels, Claudia Neuhauser, Diana Gil, Adam G Schrum
The early proximal αβ TCR signalosome specifies thymic selection outcome through a quantitative protein interaction network. Science immunology 4 (32) (2020)
Jérôme Le Nours, Nicholas A Gherardin, Sri H Ramarathinam, Wael Awad, Florian Wiede, Benjamin S Gully, Yogesh Khandokar, T Praveena, Jacinta M Wubben, Jarrod J Sandow, Andrew Ian Webb, Anouk von Borstel, Michael T Rice, Samuel J Redmond, Rebecca Seneviratna, Maria L Sandoval-Romero, Shihan Li, Michael N T Souter, Sidonia B G Eckle, Alexandra J Corbett, Hugh H Reid, Ligong Liu, David P Fairlie, Edward M Giles, Glen P Westall, Richard William Tothill, Martin S Davey, Richard Berry, Tony Tiganis, James McCluskey, Daniel G Pellicci, Anthony Wayne Purcell, Adam P Uldrich, Dale I Godfrey, Jamie Rossjohn
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science (New York, N.Y.) 366 (6472) (2020)
Huimeng Wang, Lars Kjer-Nielsen, Mai Shi, Criselle D'Souza, Troi J Pediongco, Hanwei Cao, Lyudmila Kostenko, Xin Yi Lim, Sidonia B G Eckle, Bronwyn S Meehan, Tianyuan Zhu, Bingjie Wang, Zhe Zhao, Jeffrey Y W Mak, David P Fairlie, Michele W L Teng, Jamie Rossjohn, Di Yu, Barbara Fazekas de St Groth, George Lovrecz, Louis Lu, James McCluskey, Richard A Strugnell, Alexandra J Corbett, Zhenjun Chen
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science immunology 4 (41) (2020)
Michael D Crowther, Garry Dolton, Mateusz Legut, Marine E Caillaud, Angharad Lloyd, Meriem Attaf, Sarah A E Galloway, Cristina Rius, Colin P Farrell, Barbara Szomolay, Ann Ager, Alan L Parker, Anna Fuller, Marco Donia, James McCluskey, Jamie Rossjohn, Inge Marie Svane, John D Phillips, Andrew K Sewell
Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1. Nature immunology 21 (2) (2020)
Nicholas A Gherardin, James McCluskey, Jamie Rossjohn, Dale I Godfrey
The Diverse Family of MR1-Restricted T Cells. Journal of immunology (Baltimore, Md. : 1950) 201 (10) (2019)
Manisha Pandey, Ainslie Calcutt, Victoria Ozberk, Zhenjun Chen, Matthew A Croxen, Jessica Powell, Emma Langshaw, Jamie-Lee Mills, Freda E-C Jen, James McCluskey, Jenny Robson, Gregory J Tyrrell, Michael F Good
Antibodies to the conserved region of the M protein and a streptococcal superantigen cooperatively resolve toxic shock-like syndrome in HLA-humanized mice. Science advances 5 (9) (2019)
Jan Petersen, Laura Ciacchi, Mai T Tran, Khai Lee Loh, Yvonne Kooy-Winkelaar, Nathan Paul Croft, Melinda Y Hardy, Zhenjun Chen, James McCluskey, Robert P Anderson, Anthony Wayne Purcell, Jason A Tye-Din, Frits Koning, Hugh H Reid, Jamie Rossjohn
T cell receptor cross-reactivity between gliadin and bacterial peptides in celiac disease. Nature structural & molecular biology 27 (1) (2019)
Dale I Godfrey, Hui-Fern Koay, James McCluskey, Nicholas A Gherardin
The biology and functional importance of MAIT cells. Nature immunology 20 (9) (2019)
Jennifer J Juno, Kathleen M Wragg, Thakshila Amarasena, Bronwyn S Meehan, Jeffrey Y W Mak, Ligong Liu, David P Fairlie, James McCluskey, Sidonia Barbara Guiomar Eckle, Stephen J Kent
MAIT Cells Upregulate α4β7 in Response to Acute Simian Immunodeficiency Virus/Simian HIV Infection but Are Resistant to Peripheral Depletion in Pigtail Macaques. Journal of immunology (Baltimore, Md. : 1950) 202 (7) (2019)
Hui-Fern Koay, Nicholas A Gherardin, Calvin Xu, Rebecca Seneviratna, Zhe Zhao, Zhenjun Chen, David P Fairlie, James McCluskey, Daniel G Pellicci, Adam P Uldrich, Dale I Godfrey
Diverse MR1-restricted T cells in mice and humans. Nature communications 10 (1) (2019)
Nicholas A Gherardin, Liyen Loh, Lorenztino Admojo, Alexander J Davenport, Kelden Richardson, Amy J Rogers, Phillip K Darcy, Misty R Jenkins, H Miles Prince, Simon J Harrison, Hang Quach, David P Fairlie, Katherine Kedzierska, James McCluskey, Adam P Uldrich, Paul J Neeson, David S Ritchie, Dale I Godfrey
Enumeration, functional responses and cytotoxic capacity of MAIT cells in newly diagnosed and relapsed multiple myeloma. Scientific reports 8 (1) (2018)
Bonnie van Wilgenburg, Liyen Loh, Zhenjun Chen, Troi J Pediongco, Huimeng Wang, Mai Shi, Zhe Zhao, Marios Koutsakos, Simone Nüssing, Sneha Sant, Zhongfang Wang, Criselle D'Souza, Xiaoxiao Jia, Catarina F Almeida, Lyudmila Kostenko, Sidonia Barbara Guiomar Eckle, Bronwyn S Meehan, Axel Kallies, Dale I Godfrey, Patrick C Reading, Alexandra J Corbett, James McCluskey, Paul Klenerman, Katherine Kedzierska, Timothy Stopford Christopher Hinks
MAIT cells contribute to protection against lethal influenza infection in vivo. Nature communications 9 (1) (2018)
Patricia T Illing, Phillip Pymm, Nathan Paul Croft, Hugo G Hilton, Vladimir Jojic, Alex S Han, Juan L Mendoza, Nicole A Mifsud, Nadine L Dudek, James McCluskey, Peter Parham, Jamie Rossjohn, Julian P Vivian, Anthony Wayne Purcell
HLA-B57 micropolymorphism defines the sequence and conformational breadth of the immunopeptidome. Nature communications 9 (1) (2018)
Criselle D'Souza, Troi Pediongco, Huimeng Wang, Jean-Pierre Y Scheerlinck, Lyudmila Kostenko, Robyn Esterbauer, Andrew W Stent, Sidonia Barbara Guiomar Eckle, Bronwyn S Meehan, Richard A Strugnell, Hanwei Cao, Ligong Liu, Jeffrey Y W Mak, George Lovrecz, Louis Lu, David P Fairlie, Jamie Rossjohn, James McCluskey, Alison L Every, Zhenjun Chen, Alexandra J Corbett
Mucosal-Associated Invariant T Cells Augment Immunopathology and Gastritis in Chronic Helicobacter pylori Infection. Journal of immunology (Baltimore, Md. : 1950) 200 (5) (2018)
Huimeng Wang, Criselle D'Souza, Xin Yi Lim, Lyudmila Kostenko, Troi J Pediongco, Sidonia Barbara Guiomar Eckle, Bronwyn S Meehan, Mai Shi, Nancy Wang, Shihan Li, Ligong Liu, Jeffrey Y W Mak, David P Fairlie, Yoichiro Iwakura, Jennifer M Gunnersen, Andrew W Stent, Dale I Godfrey, Jamie Rossjohn, Glen P Westall, Lars Kjer-Nielsen, Richard A Strugnell, James McCluskey, Alexandra J Corbett, Timothy Stopford Christopher Hinks, Zhenjun Chen
MAIT cells protect against pulmonary Legionella longbeachae infection. Nature communications 9 (1) (2018)
Kok Fei Chan, Benjamin S Gully, Stephanie Gras, Dennis X Beringer, Lars Kjer-Nielsen, Jonathan Cebon, James McCluskey, Weisan Chen, Jamie Rossjohn
Divergent T-cell receptor recognition modes of a HLA-I restricted extended tumour-associated peptide. Nature communications 9 (1) (2018)
Ophélie Rouxel, Jennifer Da Silva, Lucie Beaudoin, Isabelle Nel, Céline Tard, Lucie Cagninacci, Badr Kiaf, Masaya Oshima, Marc Diedisheim, Marion Salou, Alexandra J Corbett, Jamie Rossjohn, James McCluskey, Raphael Scharfmann, Manuela Battaglia, Michel Polak, Olivier Lantz, Jacques Beltrand, Agnès Lehuen
Cytotoxic and regulatory roles of mucosal-associated invariant T cells in type 1 diabetes. Nature immunology 18 (12) (2017)
Liyen Loh, Zhongfang Wang, Sneha Sant, Marios Koutsakos, Sinthujan Jegaskanda, Alexandra J Corbett, Ligong Liu, David P Fairlie, Jane Crowe, Jamie Rossjohn, Jianqing Xu, Peter C Doherty, James McCluskey, Katherine Kedzierska
Human mucosal-associated invariant T cells contribute to antiviral influenza immunity via IL-18-dependent activation. Proceedings of the National Academy of Sciences of the United States of America 113 (36) (2016)

James McCluskey.css-eqlu8i{font-size:small;padding-left:4px;} (J McCluskey)

Publication Activity (10 Years)

Top Topics

Top Venues

James McCluskey (J McCluskey)