Nicholas D Huntington

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 33

Top Venues

Nature immunology

Cancer immunology research

Nature communications

Clinical & translational immunology

Monash University

The University of Melbourne (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Monash University Feb 01 2019

Australia

Head of Immunotherapy :: Biochemistry

Education History

The University of Melbourne

Australia

PHD :: Medical Biology

Publications

Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Rebecca B Delconte, Xiangpeng Meng, Zihan Shen, Robert Hennessey, Isabella Y Kong, Iona S Schuster, Christopher E Andoniou, Melissa J Davis, Soroor Hediyeh-Zadeh, Fernando Souza-Fonseca Guimaraes, Ian A Parish, Paul A Beavis, Daniel Thiele, Michael Chopin, Mariapia A Degli-Esposti, Joseph Cursons, Axel Kallies, Jai Rautela, Stephen L Nutt, Nicholas D Huntington
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. Nature immunology (2024)
Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Rebecca B Delconte, Xiangpeng Meng, Zihan Shen, Robert Hennessey, Isabella Y Kong, Iona S Schuster, Christopher E Andoniou, Melissa J Davis, Soroor Hediyeh-Zadeh, Fernando Souza-Fonseca Guimaraes, Ian A Parish, Paul A Beavis, Daniel Thiele, Michael Chopin, Mariapia A Degli-Esposti, Joseph Cursons, Axel Kallies, Jai Rautela, Stephen L Nutt, Nicholas D Huntington
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. Nature immunology 25 (2) (2024)
Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Rebecca B Delconte, Xiangpeng Meng, Zihan Shen, Robert Hennessey, Isabella Y Kong, Iona S Schuster, Christopher E Andoniou, Melissa J Davis, Soroor Hediyeh-Zadeh, Fernando Souza-Fonseca Guimaraes, Ian A Parish, Paul A Beavis, Daniel Thiele, Michael Chopin, Mariapia A Degli-Esposti, Joseph Cursons, Axel Kallies, Jai Rautela, Stephen L Nutt, Nicholas D Huntington
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. Nature immunology 25 (2) (2024)
Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Rebecca B Delconte, Xiangpeng Meng, Zihan Shen, Robert Hennessey, Isabella Y Kong, Iona S Schuster, Christopher E Andoniou, Melissa J Davis, Soroor Hediyeh-Zadeh, Fernando Souza-Fonseca Guimaraes, Ian A Parish, Paul A Beavis, Daniel Thiele, Michael Chopin, Mariapia A Degli-Esposti, Joseph Cursons, Axel Kallies, Jai Rautela, Stephen L Nutt, Nicholas D Huntington
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. Nature immunology 25 (2) (2024)
Wilford Goh, Harrison Sudholz, Momeneh Foroutan, Sebastian Scheer, Aline Pfefferle, Rebecca B Delconte, Xiangpeng Meng, Zihan Shen, Robert Hennessey, Isabella Y Kong, Iona S Schuster, Christopher E Andoniou, Melissa J Davis, Soroor Hediyeh-Zadeh, Fernando Souza-Fonseca Guimaraes, Ian A Parish, Paul A Beavis, Daniel Thiele, Michael Chopin, Mariapia A Degli-Esposti, Joseph Cursons, Axel Kallies, Jai Rautela, Stephen L Nutt, Nicholas D Huntington
IKAROS and AIOLOS directly regulate AP-1 transcriptional complexes and are essential for NK cell development. Nature immunology 25 (2) (2024)
Aline Pfefferle, Julian Contet, Kahlia Wong, Charlotte Chen, Els Verhoeyen, Chloe K Slichter, Kimberly S Schluns, Joseph Cursons, Richard Berry, Iva Nikolic, Jai Rautela, Nicholas D Huntington
Optimisation of a primary human CAR-NK cell manufacturing pipeline. Clinical & translational immunology 13 (5) (2024)
Aline Pfefferle, Julian Contet, Kahlia Wong, Charlotte Chen, Els Verhoeyen, Chloe K Slichter, Kimberly S Schluns, Joseph Cursons, Richard Berry, Iva Nikolic, Jai Rautela, Nicholas D Huntington
Optimisation of a primary human CAR-NK cell manufacturing pipeline. Clinical & translational immunology 13 (5) (2024)
Nicholas D Huntington
Ironman training for NK cells. Nature immunology (2023)
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D Huntington, Jeffrey J Babon, Nadia J Kershaw, Zhong-Yin Zhang, Jonathan B Baell, Florian Wiede, Tony Tiganis
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. Nature communications 14 (1) (2023)
Lizeth G Meza Guzman, Craig D Hyland, Grace M Bidgood, Evelyn Leong, Zihan Shen, Wilford Goh, Jai Rautela, James E Vince, Sandra E Nicholson, Nicholas D Huntington
CD45 limits early Natural Killer cell development. Immunology and cell biology (2023)
Nicholas S Wilson, Nicholas D Huntington
Small molecule. Big biology. Dual phosphatase inhibitor enters the immunotherapy fray. Immunology and cell biology (2023)
Fernando Souza-Fonseca Guimaraes, Gustavo R Rossi, Laura F Dagley, Momeneh Foroutan, Timothy R McCulloch, Jumana Yousef, Hae-Young Park, Jennifer H Gunter, Paul A Beavis, Cheng-Yu Lin, Soroor Hediyeh-Zadeh, Tania Camilleri, Melissa J Davis, Nicholas D Huntington
TGFβ and CIS Inhibition Overcomes NK-cell Suppression to Restore Antitumor Immunity. Cancer immunology research 10 (9) (2022)
Shengbo Zhang, Jai Rautela, Naiara G Bediaga, Tatiana B Kolesnik, Yue You, Junli Nie, Laura F Dagley, Justin Bedo, Hanqing Wang, Li Sun, Robyn Sutherland, Elliot Surgenor, Nadia Iannarella, Rhys S Allan, Fernando Souza-Fonseca-Guimaraes, Yi Xie, Qike Wang, Yuxia Zhang, Yuekang Xu, Stephen L Nutt, Andrew M Lew, Nicholas D Huntington, Sandra E Nicholson, Michaël Chopin, Yifan Zhan
CIS controls the functional polarization of GM-CSF-derived macrophages. Cellular & molecular immunology (2022)
Ashleigh R Poh, Christopher G Love, David Chisanga, James H Steer, David Baloyan, Michaël Chopin, Stephen L Nutt, Jai Rautela, Nicholas D Huntington, Nima Etemadi, Megan O'Brien, Ryan N O'Keefe, Lesley G Ellies, Christophe Macri, Justine D Mintern, Lachlan W Whitehead, Gangadhara Gangadhara, Louis Boon, Ashwini L Chand, Clifford A Lowell, Wei Shi, Fiona J Pixley, Matthias Ernst
Therapeutic inhibition of the SRC-kinase HCK facilitates T cell tumor infiltration and improves response to immunotherapy. Science advances 8 (25) (2022)
Saketh S Dinavahi, Yu-Chi Chen, Kishore Punnath, Arthur Berg, Meenhard Herlyn, Momeneh Foroutan, Nicholas D Huntington, Pavan Kumar Dhanyamraju
Targeting WEE1/AKT Restores p53-Dependent Natural Killer-Cell Activation to Induce Immune Checkpoint Blockade Responses in "Cold" Melanoma. Cancer immunology research 10 (6) (2022)
Emma V Petley, Hui-Fern Koay, Melissa A Henderson, Kevin Sek, Kirsten L Todd, Simon P Keam, Junyun Lai, Imran G House, Jasmine Li, Magnus Zethoven, Amanda X Y Chen, Amanda J Oliver, Jessica Michie, Andrew J Freeman, Lauren Giuffrida, Jack D Chan, Angela Pizzolla, Jeffrey Y W Mak, Timothy R McCulloch, Fernando Souza-Fonseca-Guimaraes, Conor J Kearney, Rosemary Millen, Robert G Ramsay, Nicholas D Huntington, James McCluskey, Jane Oliaro, David P Fairlie, Paul Joseph Neeson, Dale I Godfrey, Paul A Beavis, Phillip K Darcy
MAIT cells regulate NK cell-mediated tumor immunity. Nature communications 12 (1) (2021)
Momeneh Foroutan, Ramyar Molania, Aline Pfefferle, Corina C Behrenbruch, Sebastian Scheer, Axel Kallies, Terence P Speed, Joseph Cursons, Nicholas D Huntington
The Ratio of Exhausted to Resident Infiltrating Lymphocytes Is Prognostic for Colorectal Cancer Patient Outcome. Cancer immunology research 9 (10) (2021)
Susan N Christo, Maximilien Evrard, Simone L Park, Luke C Gandolfo, Thomas N Burn, Raissa Fonseca, Dane M Newman, Yannick O Alexandre, Nicholas Collins, Natasha M Zamudio, Fernando Souza-Fonseca-Guimaraes, Daniel G Pellicci, David Chisanga, Wei Shi, Laurent Bartholin, Gabrielle T Belz, Nicholas D Huntington, Andrew Lucas, Michaela Lucas, Scott N Mueller, William R Heath, Florent Ginhoux, Terence P Speed, Francis R Carbone, Axel Kallies, Laura K Mackay
Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity. Nature immunology 22 (9) (2021)
Swee Heng Milon Pang, Joshua D'Rozario, Senora Mendonca, Tejasvini Bhuvan, Natalie L Payne, Di Zheng, Assifa Hisana, Georgia Wallis, Adele Barugahare, David R Powell, Jai Rautela, Nicholas D Huntington, Grant Dewson, David Ching Siang Huang, Daniel H D Gray, Tracy S P Heng
Mesenchymal stromal cell apoptosis is required for their therapeutic function. Nature communications 12 (1) (2021)
Jai Rautela, Elliot Surgenor, Nicholas D Huntington
Drug target validation in primary human natural killer cells using CRISPR RNP. Journal of leukocyte biology 108 (4) (2020)
Aline Pfefferle, Nicholas D Huntington
You Have Got a Fast CAR: Chimeric Antigen Receptor NK Cells in Cancer Therapy. Cancers 12 (3) (2020)
Gustavo R Rossi, Jenifer Pendiuk Gonçalves, Timothy McCulloch, Rebecca B Delconte, Robert J Hennessy, Nicholas D Huntington, Edvaldo da Silva Trindade, Fernando Souza-Fonseca Guimaraes
The Antitumor Effect of Heparin is not Mediated by Direct NK Cell Activation. Journal of clinical medicine 9 (8) (2020)
Nicholas D Huntington, Joseph Cursons, Jai Rautela
The cancer-natural killer cell immunity cycle. Nature reviews. Cancer 20 (8) (2020)
Joseph Cursons, Fernando Souza-Fonseca-Guimaraes, Momeneh Foroutan, Ashley Anderson, Frédéric Hollande, Soroor Hediyeh-Zadeh, Andreas Behren, Nicholas D Huntington, Melissa J Davis
A Gene Signature Predicting Natural Killer Cell Infiltration and Improved Survival in Melanoma Patients. Cancer immunology research 7 (7) (2019)
Robert J Hennessy, Kim Pham, Rebecca Delconte, Jai Rautela, Philip D Hodgkin, Nicholas D Huntington
Quantifying NK cell growth and survival changes in response to cytokines and regulatory checkpoint blockade helps identify optimal culture and expansion conditions. Journal of leukocyte biology 105 (6) (2019)
Jai Rautela, Laura F Dagley, Carolina Camargo de Oliveira, Iona S Schuster, Soroor Hediyeh-Zadeh, Rebecca B Delconte, Joseph Cursons, Robert Hennessy, Dana Sabine Hutchinson, Craig Harrison, Badia Kita, Éric Vivier, Andrew Ian Webb, Mariapia A Degli-Esposti, Melissa J Davis, Nicholas D Huntington, Fernando Souza-Fonseca Guimaraes
Therapeutic blockade of activin-A improves NK cell function and antitumor immunity. Science signaling 12 (596) (2019)
Kerstin Brinkmann, Ashley P Ng, Carolyn A de Graaf, Ladina Di Rago, Craig D Hyland, Eugenio Morelli, Jai Rautela, Nicholas D Huntington, Andreas Strasser, Warren S Alexander, Marco J Herold
miR17~92 restrains pro-apoptotic BIM to ensure survival of haematopoietic stem and progenitor cells. Cell death and differentiation 27 (5) (2019)
Yuhao Jiao, Joanne E Davis, Jai Rautela, Emma M Carrington, Mandy J Ludford-Menting, Wilford Goh, Rebecca B Delconte, Fernando Souza-Fonseca-Guimaraes, Rachel Koldej, Daniel Gray, David Huang, Benjamin T Kile, Andrew M Lew, David S Ritchie, Nicholas D Huntington
Recipient BCL2 inhibition and NK cell ablation form part of a reduced intensity conditioning regime that improves allo-bone marrow transplantation outcomes. Cell death and differentiation 26 (8) (2018)
Pasquale L Fedele, Simon N Willis, Yang Liao, Michael S Low, Jai Rautela, David H Segal, Jia-Nan Gong, Nicholas D Huntington, Wei Shi, David C S Huang, George Grigoriadis, Julie Tellier, Stephen L Nutt
IMiDs prime myeloma cells for daratumumab-mediated cytotoxicity through loss of Ikaros and Aiolos. Blood 132 (20) (2018)
Camille Guillerey, Nicholas D Huntington, Mark J Smyth
Targeting natural killer cells in cancer immunotherapy. Nature immunology 17 (9) (2017)
Yulong Gao, Fernando Souza-Fonseca-Guimaraes, Tobias Bald, Susanna S Ng, Arabella Young, Shin Foong Ngiow, Jai Rautela, Jasmin Straube, Nic Waddell, Stephen J Blake, Juming Yan, Laurent Bartholin, Jason S Lee, Éric Vivier, Kazuyoshi Takeda, Meriem Messaoudene, Laurence Zitvogel, Michele W L Teng, Gabrielle T Belz, Christian R Engwerda, Nicholas D Huntington, Kyohei Nakamura, Michael Hölzel, Mark J Smyth
Tumor immunoevasion by the conversion of effector NK cells into type 1 innate lymphoid cells. Nature immunology 18 (9) (2017)
Rebecca B Delconte, Tatiana B Kolesnik, Laura F Dagley, Jai Rautela, Wei Shi, Eva Maria Putz, Kimberley Stannard, Jian-Guo Zhang, Charis Teh, Matt Firth, Takashi Ushiki, Christopher E Andoniou, Mariapia A Degli-Esposti, Phillip P Sharp, Caroline E Sanvitale, Giuseppe Infusini, Nicholas P D Liau, Edmond M Linossi, Christopher J Burns, Sebastian Carotta, Daniel H D Gray, Cyril Seillet, Dana S Hutchinson, Gabrielle T Belz, Andrew I Webb, Warren S Alexander, Shawn S Li, Alex N Bullock, Jeffrey J Babon, Mark J Smyth, Sandra E Nicholson, Nicholas D Huntington
CIS is a potent checkpoint in NK cell-mediated tumor immunity. Nature immunology 17 (7) (2016)
Kevin V Chow, Rebecca B Delconte, Nicholas D Huntington, David M Tarlinton, Robyn M Sutherland, Yifan Zhan, Andrew M Lew
Innate Allorecognition Results in Rapid Accumulation of Monocyte-Derived Dendritic Cells. Journal of immunology (Baltimore, Md. : 1950) 197 (5) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Nicholas D Huntington