Tony Tiganis

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 15

Top Venues

Diabetes

Science advances

Nature communications

The EMBO journal

Yale University School of Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Yale University School of Medicine

United States

Professor Adjunct :: Department of Comparative Medicine

Peter MacCallum Cancer Centre

Australia

Head of Program :: Cancer Metabolism Program

Publications

Rhiannon Morris, Narelle Keating, Cyrus Tan, Hao Chen, Artem Laktyushin, Tamanna Saiyed, Nicholas P D Liau, Nicos A Nicola, Tony Tiganis, Nadia J Kershaw, Jeffrey J Babon
Structure guided studies of the interaction between PTP1B and JAK. Communications biology 6 (1) (2023)
Shuwei Liang, Eric Tran, Xin Du, Jiajun Dong, Harrison Sudholz, Hao Chen, Zihan Qu, Nicholas D Huntington, Jeffrey J Babon, Nadia J Kershaw, Zhong-Yin Zhang, Jonathan B Baell, Florian Wiede, Tony Tiganis
A small molecule inhibitor of PTP1B and PTPN2 enhances T cell anti-tumor immunity. Nature communications 14 (1) (2023)
Bin Qiu, Ahmed Lawan, Chrysovalantou E Xirouchaki, Jae-Sung Yi, Marie Robert, Lei Zhang, Wendy Brown, Carlos Fernández-Hernando, Xiaoyong Yang, Tony Tiganis, Anton M Bennett
MKP1 promotes nonalcoholic steatohepatitis by suppressing AMPK activity through LKB1 nuclear retention. Nature communications 14 (1) (2023)
Xin Du, Phillip K Darcy, Florian Wiede, Tony Tiganis
Targeting Protein Tyrosine Phosphatase 22 Does Not Enhance the Efficacy of Chimeric Antigen Receptor T Cells in Solid Tumors. Molecular and cellular biology 42 (3) (2022)
Anchi S Chann, Mirren Charnley, Lucas M Newton, Andrea Newbold, Florian Wiede, Tony Tiganis, Patrick O Humbert, Ricky W Johnstone, Sarah M Russell
Stepwise progression of β-selection during T cell development involves histone deacetylation. Life science alliance 6 (1) (2022)
Pei Kee Goh, Florian Wiede, Mara N Zeissig, Kara L Britt, Shuwei Liang, Tim Molloy, Nathan Goode, Rachel Xu, Sherene Loi, Mathias Muller, Patrick O Humbert, Catriona A Mclean, Tony Tiganis
PTPN2 elicits cell autonomous and non-cell autonomous effects on antitumor immunity in triple-negative breast cancer. Science advances 8 (8) (2022)
Chrysovalantou E Xirouchaki, Yaoyao Jia, Meagan J McGrath, Spencer Greatorex, Melanie Tran, Troy L Merry, Dawn Hong, Matthew J Eramo, Sophie C Broome, Jonathan S T Woodhead, Randall F D'souza, Jenny Gallagher, Ekaterina Salimova, Cheng Huang, Ralf Bernd Schittenhelm, Junichi Sadoshima, Matthew J Watt, Christina A Mitchell, Tony Tiganis
Skeletal muscle NOX4 is required for adaptive responses that prevent insulin resistance. Science advances 7 (51) (2021)
Garron T Dodd, Seung Jae Kim, Mathieu Méquinion, Chrysovalantou E Xirouchaki, Jens C Brüning, Zane B Andrews, Tony Tiganis
Insulin signaling in AgRP neurons regulates meal size to limit glucose excursions and insulin resistance. Science advances 7 (9) (2021)
Jérôme Le Nours, Nicholas A Gherardin, Sri H Ramarathinam, Wael Awad, Florian Wiede, Benjamin S Gully, Yogesh Khandokar, T Praveena, Jacinta M Wubben, Jarrod J Sandow, Andrew Ian Webb, Anouk von Borstel, Michael T Rice, Samuel J Redmond, Rebecca Seneviratna, Maria L Sandoval-Romero, Shihan Li, Michael N T Souter, Sidonia B G Eckle, Alexandra J Corbett, Hugh H Reid, Ligong Liu, David P Fairlie, Edward M Giles, Glen P Westall, Richard William Tothill, Martin S Davey, Richard Berry, Tony Tiganis, James McCluskey, Daniel G Pellicci, Anthony Wayne Purcell, Adam P Uldrich, Dale I Godfrey, Jamie Rossjohn
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science (New York, N.Y.) 366 (6472) (2020)
Florian Wiede, Thomas C Brodnicki, Pei Kee Goh, Yew A Leong, Gareth W Jones, Di Yu, Alan G Baxter, Simon A Jones, Thomas W H Kay, Tony Tiganis
T-Cell-Specific PTPN2 Deficiency in NOD Mice Accelerates the Development of Type 1 Diabetes and Autoimmune Comorbidities. Diabetes 68 (6) (2019)
Florian Wiede, Kun-Hui Lu, Xin Du, Shuwei Liang, Katharina Hochheiser, Garron T Dodd, Pei K Goh, Conor Kearney, Deborah Meyran, Paul A Beavis, Melissa A Henderson, Simone L Park, Jason Waithman, Sheng Zhang, Zhong-Yin Zhang, Jane Oliaro, Thomas Gebhardt, Phillip K Darcy, Tony Tiganis
PTPN2 phosphatase deletion in T cells promotes anti-tumour immunity and CAR T-cell efficacy in solid tumours. The EMBO journal 39 (2) (2019)
Garron T Dodd, Natalie Jane Michael, Robert S Lee-Young, Salvatore P Mangiafico, Jack T Pryor, Astrid C Munder, Stephanie E Simonds, Jens Claus Brüning, Zhong-Yin Zhang, Michael A Cowley, Sofianos Andrikopoulos, Tamas L Horvath, David Spanswick, Tony Tiganis
Insulin regulates POMC neuronal plasticity to control glucose metabolism. eLife 7 (2018)
Garron T Dodd, Robert S Lee-Young, Jens C Brüning, Tony Tiganis
TCPTP Regulates Insulin Signaling in AgRP Neurons to Coordinate Glucose Metabolism With Feeding. Diabetes 67 (7) (2018)
Katrin Pfuhlmann, Sonja C Schriever, Peter Baumann, Dhiraj G Kabra, Luke Harrison, Sithandiwe E Mazibuko-Mbeje, Raian E Contreras, Eleni Kyriakou, Stephanie E Simonds, Tony Tiganis, Michael A Cowley, Stephen C Woods, Martin Jastroch, Christoffer Clemmensen, Meri De Angelis, Karl-Werner Schramm, Michael Sattler, Ana C Messias, Matthias H Tschöp, Paul Thomas Pfluger
Celastrol-Induced Weight Loss Is Driven by Hypophagia and Independent From UCP1. Diabetes 67 (11) (2018)
Florian Wiede, Jarrod A Dudakov, Kun-Hui Lu, Garron T Dodd, Tariq Butt, Dale I Godfrey, Andreas Strasser, Richard L Boyd, Tony Tiganis
PTPN2 regulates T cell lineage commitment and αβ versus γδ specification. The Journal of experimental medicine 214 (9) (2017)

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Publication Activity (10 Years)

Top Topics

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Tony Tiganis