David P Fairlie (D P Fairlie)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 77

Top Venues

Science immunology

Angewandte Chemie (International ed. in English)

Journal of immunology (Baltimore, Md. : 1950)

Journal of medicinal chemistry

University of Queensland

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Queensland

Australia

Division Head and Group Leader :: Institute for Molecular Bioscience

Publications

Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, Jeffrey Y W Mak, David P Fairlie, Takeshi Bamba, Eri Ishikawa, Masamichi Nagae, Jamie Rossjohn, Sho Yamasaki
Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology 9 (91) (2024)
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, Johanna Emgård, Kimia T Maleki, Takuya Sekine, Olga Rivera-Ballesteros, null null, Sara Gredmark-Russ, Olav Rooyackers, Magdalena Skagerberg, Lars I Eriksson, Anna Norrby-Teglund, Jeffrey Y W Mak, David P Fairlie, Niklas K Björkström, Jonas Klingström, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Kristoffer Strålin, Johan K Sandberg
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies. Journal of immunology (Baltimore, Md. : 1950) 212 (3) (2024)
Yichao Zheng, Fei Han, Zhengyu Wu, Bingjie Wang, Xingchi Chen, Caroline Boulouis, Yuebin Jiang, Amanda Ho, Dan He, Wan Rong Sia, Jeffrey Y W Mak, David P Fairlie, Lin-Fa Wang, Johan K Sandberg, Peter E Lobie, Shaohua Ma, Edwin Leeansyah
MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis. Science advances 10 (24) (2024)
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, Johanna Emgård, Kimia T Maleki, Takuya Sekine, Olga Rivera-Ballesteros, null null, Sara Gredmark-Russ, Olav Rooyackers, Magdalena Skagerberg, Lars I Eriksson, Anna Norrby-Teglund, Jeffrey Y W Mak, David P Fairlie, Niklas K Björkström, Jonas Klingström, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Kristoffer Strålin, Johan K Sandberg
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies. Journal of immunology (Baltimore, Md. : 1950) 212 (3) (2024)
Jeffrey Y W Mak, Ryan J D Rivero, Huy N Hoang, Xin Yi Lim, Jieru Deng, Hamish E G McWilliam, Jose A Villadangos, James McCluskey, Alexandra J Corbett, David P Fairlie
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis. Angewandte Chemie (International ed. in English) 63 (31) (2024)
Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, Jeffrey Y W Mak, David P Fairlie, Takeshi Bamba, Eri Ishikawa, Masamichi Nagae, Jamie Rossjohn, Sho Yamasaki
Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology 9 (91) (2024)
Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, Jeffrey Y W Mak, David P Fairlie, Takeshi Bamba, Eri Ishikawa, Masamichi Nagae, Jamie Rossjohn, Sho Yamasaki
Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology 9 (91) (2024)
Eunice K Poon, Ligong Liu, Kai-Chen Wu, Junxian Lim, Matthew J Sweet, Rink-Jan Lohman, Abishek Iyer, David P Fairlie
A novel inhibitor of class IIa histone deacetylases attenuates collagen-induced arthritis. British journal of pharmacology (2024)
Jeffrey Y W Mak, Ryan J D Rivero, Huy N Hoang, Xin Yi Lim, Jieru Deng, Hamish E G McWilliam, Jose A Villadangos, James McCluskey, Alexandra J Corbett, David P Fairlie
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis. Angewandte Chemie (International ed. in English) 63 (31) (2024)
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, Johanna Emgård, Kimia T Maleki, Takuya Sekine, Olga Rivera-Ballesteros, null null, Sara Gredmark-Russ, Olav Rooyackers, Magdalena Skagerberg, Lars I Eriksson, Anna Norrby-Teglund, Jeffrey Y W Mak, David P Fairlie, Niklas K Björkström, Jonas Klingström, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Kristoffer Strålin, Johan K Sandberg
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies. Journal of immunology (Baltimore, Md. : 1950) 212 (3) (2024)
Himani Shah, David P Fairlie, Junxian Lim
Protease-activated receptor 2: a promising therapeutic target for women's cancers. The Journal of pharmacology and experimental therapeutics (2024)
Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, Jeffrey Y W Mak, David P Fairlie, Takeshi Bamba, Eri Ishikawa, Masamichi Nagae, Jamie Rossjohn, Sho Yamasaki
Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology 9 (91) (2024)
Yichao Zheng, Fei Han, Zhengyu Wu, Bingjie Wang, Xingchi Chen, Caroline Boulouis, Yuebin Jiang, Amanda Ho, Dan He, Wan Rong Sia, Jeffrey Y W Mak, David P Fairlie, Lin-Fa Wang, Johan K Sandberg, Peter E Lobie, Shaohua Ma, Edwin Leeansyah
MAIT cell activation and recruitment in inflammation and tissue damage in acute appendicitis. Science advances 10 (24) (2024)
Jeffrey Y W Mak, Ryan J D Rivero, Huy N Hoang, Xin Yi Lim, Jieru Deng, Hamish E G McWilliam, Jose A Villadangos, James McCluskey, Alexandra J Corbett, David P Fairlie
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis. Angewandte Chemie (International ed. in English) (2024)
Emi Ito, Shinsuke Inuki, Yoshihiro Izumi, Masatomo Takahashi, Yuki Dambayashi, Lisa Ciacchi, Wael Awad, Ami Takeyama, Kensuke Shibata, Shotaro Mori, Jeffrey Y W Mak, David P Fairlie, Takeshi Bamba, Eri Ishikawa, Masamichi Nagae, Jamie Rossjohn, Sho Yamasaki
Sulfated bile acid is a host-derived ligand for MAIT cells. Science immunology 9 (91) (2024)
Tobias Kammann, Curtis Cai, Takuya Sekine, Elli Mouchtaridi, Caroline Boulouis, Vera Nilsén, Olga Rivera Ballesteros, Thomas R Müller, Yu Gao, Elisa J M Raineri, Akhirunnesa Mily, Sarah Adamo, Christian Constantz, Julia Niessl, Whitney Weigel, Efthymia Kokkinou, Christopher T Stamper, Anne Marchalot, John Bassett, Sabrina Ferreira, Inga Rødahl, Nicole Wild, Demi Brownlie, Christopher Andrew Tibbitt, Jeffrey Y W Mak, David P Fairlie, Edwin Leeansyah, Jakob Michaelsson, Nicole Marquardt, Jenny Mjösberg, Carl Jorns, Marcus Buggert, Johan K Sandberg
MAIT cell heterogeneity across paired human tissues reveals specialization of distinct regulatory and enhanced effector profiles. Science immunology 9 (99) (2024)
Jeffrey Y W Mak, Ryan J D Rivero, Huy N Hoang, Xin Yi Lim, Jieru Deng, Hamish E G McWilliam, Jose A Villadangos, James McCluskey, Alexandra J Corbett, David P Fairlie
Potent Immunomodulators Developed from an Unstable Bacterial Metabolite of Vitamin B2 Biosynthesis. Angewandte Chemie (International ed. in English) 63 (31) (2024)
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, Johanna Emgård, Kimia T Maleki, Takuya Sekine, Olga Rivera-Ballesteros, null null, Sara Gredmark-Russ, Olav Rooyackers, Magdalena Skagerberg, Lars I Eriksson, Anna Norrby-Teglund, Jeffrey Y W Mak, David P Fairlie, Niklas K Björkström, Jonas Klingström, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Kristoffer Strålin, Johan K Sandberg
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies. Journal of immunology (Baltimore, Md. : 1950) (2023)
Angela A Salim, Waleed M Hussein, Pradeep Dewapriya, Huy N Hoang, Yahao Zhou, Kaumadi Samarasekera, Zeinab G Khalil, David P Fairlie, Robert J Capon
Talarolides Revisited: Cyclic Heptapeptides from an Australian Marine Tunicate-Associated Fungus, Talaromyces sp. CMB-TU011. Marine drugs 21 (9) (2023)
Nidhish Francis, Reza Sanaei, Babatunde A Ayodele, Neil M O'Brien-Simpson, David P Fairlie, Lakshmi C Wijeyewickrema, Robert N Pike, Eleanor Jean Mackie, Charles Neil Pagel
Effect of a protease-activated receptor-2 antagonist (GB88) on inflammation-related loss of alveolar bone in periodontal disease. Journal of periodontal research (2023)
Kaustav Das Gupta, Divya Ramnath, Jessica B von Pein, James E B Curson, Yizhuo Wang, Rishika Abrol, Asha Kakkanat, Shayli Varasteh Moradi, Kimberley S Gunther, Ambika M V Murthy, Claudia J Stocks, Ronan Kapetanovic, Robert C Reid, Abishek Iyer, Zoe C Ilka, William M Nauseef, Manuel Plan, Lin Luo, Jennifer L Stow, Kate Schroder, Denuja Karunakaran, Kirill Alexandrov, Melanie R Shakespear, Mark A Schembri, David P Fairlie, Matthew J Sweet
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences of the United States of America 120 (4) (2023)
Kaustav Das Gupta, Divya Ramnath, Jessica B von Pein, James E B Curson, Yizhuo Wang, Rishika Abrol, Asha Kakkanat, Shayli Varasteh Moradi, Kimberley S Gunther, Ambika M V Murthy, Claudia J Stocks, Ronan Kapetanovic, Robert C Reid, Abishek Iyer, Zoe C Ilka, William M Nauseef, Manuel Plan, Lin Luo, Jennifer L Stow, Kate Schroder, Denuja Karunakaran, Kirill Alexandrov, Melanie R Shakespear, Mark A Schembri, David P Fairlie, Matthew J Sweet
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences of the United States of America 120 (4) (2023)
Kaustav Das Gupta, Divya Ramnath, Jessica B von Pein, James E B Curson, Yizhuo Wang, Rishika Abrol, Asha Kakkanat, Shayli Varasteh Moradi, Kimberley S Gunther, Ambika M V Murthy, Claudia J Stocks, Ronan Kapetanovic, Robert C Reid, Abishek Iyer, Zoe C Ilka, William M Nauseef, Manuel Plan, Lin Luo, Jennifer L Stow, Kate Schroder, Denuja Karunakaran, Kirill Alexandrov, Melanie R Shakespear, Mark A Schembri, David P Fairlie, Matthew J Sweet
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences of the United States of America 120 (4) (2023)
Kaustav Das Gupta, Divya Ramnath, Jessica B von Pein, James E B Curson, Yizhuo Wang, Rishika Abrol, Asha Kakkanat, Shayli Varasteh Moradi, Kimberley S Gunther, Ambika M V Murthy, Claudia J Stocks, Ronan Kapetanovic, Robert C Reid, Abishek Iyer, Zoe C Ilka, William M Nauseef, Manuel Plan, Lin Luo, Jennifer L Stow, Kate Schroder, Denuja Karunakaran, Kirill Alexandrov, Melanie R Shakespear, Mark A Schembri, David P Fairlie, Matthew J Sweet
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences of the United States of America 120 (4) (2023)
Rachel F Rollo, Giorgia Mori, Timothy A Hill, Doris Hillemann, Stefan Niemann, Susanne Homolka, David P Fairlie, Antje Blumenthal
Wollamide Cyclic Hexapeptides Synergize with Established and New Tuberculosis Antibiotics in Targeting Mycobacterium tuberculosis. Microbiology spectrum (2023)
Himani Shah, Timothy A Hill, Junxian Lim, David P Fairlie
Protease-activated receptor 2 attenuates doxorubicin-induced apoptosis in colon cancer cells. Journal of cell communication and signaling (2023)
Kaustav Das Gupta, Divya Ramnath, Jessica B von Pein, James E B Curson, Yizhuo Wang, Rishika Abrol, Asha Kakkanat, Shayli Varasteh Moradi, Kimberley S Gunther, Ambika M V Murthy, Claudia J Stocks, Ronan Kapetanovic, Robert C Reid, Abishek Iyer, Zoe C Ilka, William M Nauseef, Manuel Plan, Lin Luo, Jennifer L Stow, Kate Schroder, Denuja Karunakaran, Kirill Alexandrov, Melanie R Shakespear, Mark A Schembri, David P Fairlie, Matthew J Sweet
HDAC7 is an immunometabolic switch triaging danger signals for engagement of antimicrobial versus inflammatory responses in macrophages. Proceedings of the National Academy of Sciences of the United States of America 120 (4) (2023)
Dimitrios Triantafyllos Gerokonstantis, Christiana Mantzourani, Dimitrios Gkikas, Kai-Chen Wu, Huy N Hoang, Ierasia Triandafillidi, Ilianna Barbayianni, Paraskevi Kanellopoulou, Alexandros C Kokotos, Panagiota Moutevelis-Minakakis, Vassilis Aidinis, Panagiotis K Politis, David P Fairlie, George Kokotos
N -(2-Aminophenyl)-benzamide Inhibitors of Class I HDAC Enzymes with Antiproliferative and Antifibrotic Activity. Journal of medicinal chemistry (2023)
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, Johanna Emgård, Kimia T Maleki, Takuya Sekine, Olga Rivera-Ballesteros, null null, Sara Gredmark-Russ, Olav Rooyackers, Magdalena Skagerberg, Lars I Eriksson, Anna Norrby-Teglund, Jeffrey Y W Mak, David P Fairlie, Niklas K Björkström, Jonas Klingström, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Kristoffer Strålin, Johan K Sandberg
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies. Journal of immunology (Baltimore, Md. : 1950) (2023)
Tobias Kammann, Jean-Baptiste Gorin, Tiphaine Parrot, Yu Gao, Andrea Ponzetta, Johanna Emgård, Kimia T Maleki, Takuya Sekine, Olga Rivera-Ballesteros, null null, Sara Gredmark-Russ, Olav Rooyackers, Magdalena Skagerberg, Lars I Eriksson, Anna Norrby-Teglund, Jeffrey Y W Mak, David P Fairlie, Niklas K Björkström, Jonas Klingström, Hans-Gustaf Ljunggren, Soo Aleman, Marcus Buggert, Kristoffer Strålin, Johan K Sandberg
Dynamic MAIT Cell Recovery after Severe COVID-19 Is Transient with Signs of Heterogeneous Functional Anomalies. Journal of immunology (Baltimore, Md. : 1950) (2023)
Eva Hesping, Ming Jang Chua, Marc Pflieger, Yunan Qian, Lilong Dong, Prabhakar Bachu, Ligong Liu, Thomas Kurz, Gillian M Fisher, Tina S Skinner-Adams, Robert C Reid, David P Fairlie, Katherine T Andrews, Alain-Dominique J P Gorse
QSAR Classification Models for Prediction of Hydroxamate Histone Deacetylase Inhibitor Activity against Malaria Parasites. ACS infectious diseases 8 (1) (2022)
Lauren J Howson, Wael Awad, Anouk von Borstel, Hui Jing Lim, Hamish E G McWilliam, Maria L Sandoval-Romero, Shamik Majumdar, Abdul Rezzak Hamzeh, T Daniel Andrews, David H McDermott, Philip M Murphy, Jérôme Le Nours, Jeffrey Y W Mak, Ligong Liu, David P Fairlie, James McCluskey, Jose A Villadangos, Matthew C Cook, Stephen J Turner, Martin S Davey, Samar Ojaimi, Jamie Rossjohn
Absence of mucosal-associated invariant T cells in a person with a homozygous point mutation in MR1. Science immunology 5 (49) (2022)
Aline Dantas de Araujo, Huy N Hoang, Junxian Lim, Jeffrey Y W Mak, David P Fairlie
Tuning Electrostatic and Hydrophobic Surfaces of Aromatic Rings to Enhance Membrane Association and Cell Uptake of Peptides. Angewandte Chemie (International ed. in English) 61 (29) (2022)
Chongyang Wu, Huy N Hoang, Timothy A Hill, Junxian Lim, W Mei Kok, Kalyani Akondi, Ligong Liu, David P Fairlie
Helical structure in cyclic peptides: effect of N -methyl amides versus esters. Chemical communications (Cambridge, England) 58 (89) (2022)
Aline Dantas de Araujo, Junxian Lim, Kai-Chen Wu, Huy N Hoang, Huy T Nguyen, David P Fairlie
Landscaping macrocyclic peptides: stapling hDM2-binding peptides for helicity, protein affinity, proteolytic stability and cell uptake. RSC chemical biology 3 (7) (2022)
Peiqi Wang, Timothy A Hill, Justin Mitchell, Rebecca L Fitzsimmons, Weijun Xu, Zhixuan Loh, Jacky Y Suen, Junxian Lim, Abishek Iyer, David P Fairlie
Modifying a Hydroxyl Patch in Glucagon-like Peptide 1 Produces Biased Agonists with Unique Signaling Profiles. Journal of medicinal chemistry 65 (17) (2022)
Michael N T Souter, Wael Awad, Shihan Li, Troi J Pediongco, Bronwyn S Meehan, Lucy J Meehan, Zehua Tian, Zhe Zhao, Huimeng Wang, Adam Nelson, Jérôme Le Nours, Yogesh B Khandokar, T Praveena, Jacinta Wubben, Jie Lin, Lucy C Sullivan, George O Lovrecz, Jeffrey Y W Mak, Ligong Liu, Lyudmila Kostenko, Katherine Kedzierska, Alexandra J Corbett, David P Fairlie, Andrew G Brooks, Nicholas A Gherardin, Adam P Uldrich, Zhenjun Chen, Jamie Rossjohn, Dale I Godfrey, James McCluskey, Daniel G Pellicci, Sidonia Barbara Guiomar Eckle
CD8 coreceptor engagement of MR1 enhances antigen responsiveness by human MAIT and other MR1-reactive T cells. The Journal of experimental medicine 219 (9) (2022)
Hui Jing Lim, Jacinta M Wubben, Cristian Pinero Garcia, Sebastian Cruz-Gomez, Jieru Deng, Jeffrey Y W Mak, Abderrahman Hachani, Regan J Anderson, Gavin A Painter, Jesse Goyette, Shanika L Amarasinghe, Matthew E Ritchie, Antoine Roquilly, David P Fairlie, Katharina Gaus, Jamie Rossjohn, Jose A Villadangos, Hamish E G McWilliam
A specialized tyrosine-based endocytosis signal in MR1 controls antigen presentation to MAIT cells. The Journal of cell biology 221 (12) (2022)
Emma V Petley, Hui-Fern Koay, Melissa A Henderson, Kevin Sek, Kirsten L Todd, Simon P Keam, Junyun Lai, Imran G House, Jasmine Li, Magnus Zethoven, Amanda X Y Chen, Amanda J Oliver, Jessica Michie, Andrew J Freeman, Lauren Giuffrida, Jack D Chan, Angela Pizzolla, Jeffrey Y W Mak, Timothy R McCulloch, Fernando Souza-Fonseca-Guimaraes, Conor J Kearney, Rosemary Millen, Robert G Ramsay, Nicholas D Huntington, James McCluskey, Jane Oliaro, David P Fairlie, Paul Joseph Neeson, Dale I Godfrey, Paul A Beavis, Phillip K Darcy
MAIT cells regulate NK cell-mediated tumor immunity. Nature communications 12 (1) (2021)
Huy N Hoang, Timothy A Hill, David P Fairlie
Connecting Hydrophobic Surfaces in Cyclic Peptides Increases Membrane Permeability. Angewandte Chemie (International ed. in English) 60 (15) (2021)
Kai-En Chen, Qian Guo, Timothy A Hill, Yi Cui, Amy K Kendall, Zhe Yang, Ryan J Hall, Michael D Healy, Joanna Sacharz, Suzanne J Norwood, Sachini Fonseka, Boyang Xie, Robert C Reid, Natalya Leneva, Robert G Parton, Rajesh Ghai, David Arthur Stroud, David P Fairlie, Hiroaki Suga, Lauren Parker Jackson, Rohan D Teasdale, Toby Passioura, Brett M Collins
De novo macrocyclic peptides for inhibiting, stabilizing, and probing the function of the retromer endosomal trafficking complex. Science advances 7 (49) (2021)
Aline Dantas de Araujo, Huy T Nguyen, David P Fairlie
Late-Stage Hydrocarbon Conjugation and Cyclisation in Synthetic Peptides and Proteins. Chembiochem : a European journal of chemical biology 22 (10) (2021)
Jeffrey Y W Mak, Ligong Liu, David P Fairlie
Chemical Modulators of Mucosal Associated Invariant T Cells. Accounts of chemical research 54 (17) (2021)
Divya Ramnath, Kaustav Das Gupta, Yizhuo Wang, Rishika Abrol, James E B Curson, Junxian Lim, Robert C Reid, Ashley Mansell, Antje Blumenthal, Denuja Karunakaran, David P Fairlie, Matthew J Sweet
The histone deacetylase Hdac7 supports LPS-inducible glycolysis and Il-1β production in murine macrophages via distinct mechanisms. Journal of leukocyte biology (2021)
Lauren J Howson, Jasmine Li, Anouk von Borstel, Adele Barugahare, Jeffrey Y W Mak, David P Fairlie, James McCluskey, Stephen J Turner, Martin S Davey, Jamie Rossjohn
Mucosal-Associated Invariant T Cell Effector Function Is an Intrinsic Cell Property That Can Be Augmented by the Metabolic Cofactor α-Ketoglutarate. Journal of immunology (Baltimore, Md. : 1950) 206 (7) (2021)
Sarah K Madden, Aline Dantas de Araujo, Mara Gerhardt, David P Fairlie, Jody M Mason
Taking the Myc out of cancer: toward therapeutic strategies to directly inhibit c-Myc. Molecular cancer 20 (1) (2021)
Jeffrey Y W Mak, Kai-Chen Wu, Praveer K Gupta, Sheila Barbero, Maddison G McLaughlin, Andrew J Lucke, Jiahui Tng, Junxian Lim, Zhixuan Loh, Matthew J Sweet, Robert C Reid, Ligong Liu, David P Fairlie
HDAC7 Inhibition by Phenacetyl and Phenylbenzoyl Hydroxamates. Journal of medicinal chemistry 64 (4) (2021)
Zhe Zhao, Huimeng Wang, Mai Shi, Tianyuan Zhu, Troi Pediongco, Xin Yi Lim, Bronwyn S Meehan, Adam G Nelson, David P Fairlie, Jeffrey Y W Mak, Sidonia Barbara Guiomar Eckle, Marcela L Moreira, Carolin Tumpach, Michael Bramhall, Cameron G Williams, Hyun Jae Lee, Ashraful Haque, Maximilien Evrard, Jamie Rossjohn, James McCluskey, Alexandra J Corbett, Zhenjun Chen
Francisella tularensis induces Th1 like MAIT cells conferring protection against systemic and local infection. Nature communications 12 (1) (2021)
Caroline Boulouis, Wan Rong Sia, Muhammad Yaaseen Gulam, Jocelyn Qi-Min Teo, Yi Tian Png, Thanh Kha Phan, Jeffrey Y W Mak, David P Fairlie, Ivan K H Poon, Tse Hsien Koh, Peter Bergman, Chwee Ming Lim, Lin-Fa Wang, Andrea Lay Hoon Kwa, Johan K Sandberg, Edwin Leeansyah
Human MAIT cell cytolytic effector proteins synergize to overcome carbapenem resistance in Escherichia coli. PLoS biology 18 (6) (2020)
Wael Awad, Geraldine J M Ler, Weijun Xu, Andrew N Keller, Jeffrey Y W Mak, Xin Yi Lim, Ligong Liu, Sidonia Barbara Guiomar Eckle, Jérôme Le Nours, James McCluskey, Alexandra J Corbett, David P Fairlie, Jamie Rossjohn
The molecular basis underpinning the potency and specificity of MAIT cell antigens. Nature immunology 21 (4) (2020)
Patricia Lopez-Garcia, Aline Dantas de Araujo, Ana Elisa Bergues-Pupo, Isabell Tunn, David P Fairlie, Kerstin G Blank
Fortified Coiled Coils: Enhancing Mechanical Stability with Lactam or Metal Staples. Angewandte Chemie (International ed. in English) 60 (1) (2020)
Hui-Fern Koay, S Su, Daniela Amann-Zalcenstein, Stephen R Daley, Iain Comerford, L Miosge, Carly E Whyte, I E Konstantinov, Y d'Udekem, T Baldwin, Peter F Hickey, S P Berzins, Jeffrey Y W Mak, Yovina Sontani, C M Roots, T Sidwell, A Kallies, Zhenjun Chen, Simone Nüssing, Katherine Kedzierska, Laura K Mackay, Shaun R McColl, Elissa K Deenick, David P Fairlie, James McCluskey, Christopher C Goodnow, M E Ritchie, Gabrielle T Belz, Shalin H Naik, Daniel G Pellicci, Dale I Godfrey
A divergent transcriptional landscape underpins the development and functional branching of MAIT cells. Science immunology 4 (41) (2020)
Ronan Kapetanovic, Syeda Farhana Afroz, Divya Ramnath, Grace Mep Lawrence, Takashi Okada, James E B Curson, Jost de Bruin, David P Fairlie, Kate Schroder, Justin C St John, Antje Blumenthal, Matthew J Sweet
Lipopolysaccharide promotes Drp1-dependent mitochondrial fission and associated inflammatory responses in macrophages. Immunology and cell biology 98 (7) (2020)
Jessica A Rowley, Robert C Reid, Eunice K Y Poon, Kai-Chen Wu, Junxian Lim, Rink-Jan Lohman, Johan K Hamidon, Mei-Kwan Yau, Maria A Halili, Thomas Durek, Abishek Iyer, David P Fairlie
Potent Thiophene Antagonists of Human Complement C3a Receptor with Anti-Inflammatory Activity. Journal of medicinal chemistry 63 (2) (2020)
Hamish E G McWilliam, Jeffrey Y W Mak, Wael Awad, Matthew Zorkau, Sebastian Cruz-Gomez, Hui Jing Lim, Yuting Yan, Sam Wormald, Laura F Dagley, Sidonia Barbara Guiomar Eckle, Alexandra J Corbett, Haiyin Liu, Shihan Li, Scott J J Reddiex, Justine D Mintern, Ligong Liu, James McCluskey, Jamie Rossjohn, David P Fairlie, Jose A Villadangos
Endoplasmic reticulum chaperones stabilize ligand-receptive MR1 molecules for efficient presentation of metabolite antigens. Proceedings of the National Academy of Sciences of the United States of America 117 (40) (2020)
Kana Maruyama-Fumoto, John J McGuire, David P Fairlie, Kazumasa Shinozuka, Satomi Kagota
Activation of protease-activated receptor 2 is associated with blood pressure regulation and proteinuria reduction in metabolic syndrome. Clinical and experimental pharmacology & physiology 48 (2) (2020)
Jérôme Le Nours, Nicholas A Gherardin, Sri H Ramarathinam, Wael Awad, Florian Wiede, Benjamin S Gully, Yogesh Khandokar, T Praveena, Jacinta M Wubben, Jarrod J Sandow, Andrew Ian Webb, Anouk von Borstel, Michael T Rice, Samuel J Redmond, Rebecca Seneviratna, Maria L Sandoval-Romero, Shihan Li, Michael N T Souter, Sidonia B G Eckle, Alexandra J Corbett, Hugh H Reid, Ligong Liu, David P Fairlie, Edward M Giles, Glen P Westall, Richard William Tothill, Martin S Davey, Richard Berry, Tony Tiganis, James McCluskey, Daniel G Pellicci, Anthony Wayne Purcell, Adam P Uldrich, Dale I Godfrey, Jamie Rossjohn
A class of γδ T cell receptors recognize the underside of the antigen-presenting molecule MR1. Science (New York, N.Y.) 366 (6472) (2020)
Huimeng Wang, Lars Kjer-Nielsen, Mai Shi, Criselle D'Souza, Troi J Pediongco, Hanwei Cao, Lyudmila Kostenko, Xin Yi Lim, Sidonia B G Eckle, Bronwyn S Meehan, Tianyuan Zhu, Bingjie Wang, Zhe Zhao, Jeffrey Y W Mak, David P Fairlie, Michele W L Teng, Jamie Rossjohn, Di Yu, Barbara Fazekas de St Groth, George Lovrecz, Louis Lu, James McCluskey, Richard A Strugnell, Alexandra J Corbett, Zhenjun Chen
IL-23 costimulates antigen-specific MAIT cell activation and enables vaccination against bacterial infection. Science immunology 4 (41) (2020)
Jiahui Tng, Junxian Lim, Kai-Chen Wu, Andrew J Lucke, Weijun Xu, Robert C Reid, David P Fairlie
Achiral Derivatives of Hydroxamate AR-42 Potently Inhibit Class I HDAC Enzymes and Cancer Cell Proliferation. Journal of medicinal chemistry 63 (11) (2020)
Huy N Hoang, Chongyang Wu, Timothy A Hill, Aline Dantas de Araujo, Paul V Bernhardt, Ligong Liu, David P Fairlie
A Novel Long-Range n to π* Interaction Secures the Smallest known α-Helix in Water. Angewandte Chemie (International ed. in English) 58 (52) (2019)
Rink-Jan Lohman, Daniel S Nielsen, W Mei Kok, Huy N Hoang, Timothy A Hill, David P Fairlie
Mirror image pairs of cyclic hexapeptides have different oral bioavailabilities and metabolic stabilities. Chemical communications (Cambridge, England) 55 (89) (2019)
Zhixuan Loh, Rebecca L Fitzsimmons, Robert C Reid, Divya Ramnath, Andrew Clouston, Praveer K Gupta, Katharine M Irvine, Elizabeth E Powell, Kate Schroder, Jennifer L Stow, Matthew J Sweet, David P Fairlie, Abishek Iyer
Inhibitors of class I histone deacetylases attenuate thioacetamide-induced liver fibrosis in mice by suppressing hepatic type 2 inflammation. British journal of pharmacology 176 (19) (2019)
Huy N Hoang, Timothy A Hill, Gloria Ruiz-Gómez, Frederik Diness, Jody M Mason, Chongyang Wu, Giovanni Abbenante, Nicholas E Shepherd, David P Fairlie
Twists or turns: stabilising alpha vs. beta turns in tetrapeptides. Chemical science 10 (45) (2019)
Geraldine J M Ler, Weijun Xu, Jeffrey Y W Mak, Ligong Liu, Paul V Bernhardt, David P Fairlie
Computer Modelling and Synthesis of Deoxy and Monohydroxy Analogues of a Ribitylaminouracil Bacterial Metabolite that Potently Activates Human T Cells. Chemistry (Weinheim an der Bergstrasse, Germany) 25 (68) (2019)
Jennifer J Juno, Kathleen M Wragg, Thakshila Amarasena, Bronwyn S Meehan, Jeffrey Y W Mak, Ligong Liu, David P Fairlie, James McCluskey, Sidonia Barbara Guiomar Eckle, Stephen J Kent
MAIT Cells Upregulate α4β7 in Response to Acute Simian Immunodeficiency Virus/Simian HIV Infection but Are Resistant to Peripheral Depletion in Pigtail Macaques. Journal of immunology (Baltimore, Md. : 1950) 202 (7) (2019)
Alpeshkumar K Malde, Timothy A Hill, Abishek Iyer, David P Fairlie
Crystal Structures of Protein-Bound Cyclic Peptides. Chemical reviews 119 (17) (2019)
Hui-Fern Koay, Nicholas A Gherardin, Calvin Xu, Rebecca Seneviratna, Zhe Zhao, Zhenjun Chen, David P Fairlie, James McCluskey, Daniel G Pellicci, Adam P Uldrich, Dale I Godfrey
Diverse MR1-restricted T cells in mice and humans. Nature communications 10 (1) (2019)
Aline Dantas de Araujo, Junxian Lim, Kai-Chen Wu, Yibin Xiang, Andrew C Good, Renato Skerlj, David P Fairlie
Bicyclic Helical Peptides as Dual Inhibitors Selective for Bcl2A1 and Mcl-1 Proteins. Journal of medicinal chemistry 61 (7) (2018)
Soo-Hyun Kim, Richard P Redvers, Lap Hing Chi, Xiawei Ling, Andrew J Lucke, Robert C Reid, David P Fairlie, Ana Carolina Baptista Moreno Martin, Robin L Anderson, Delphine Denoyer, Normand Pouliot
Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis. Disease models & mechanisms 11 (7) (2018)
Aline Dantas de Araujo, Samuel R Perry, David P Fairlie
Chemically Diverse Helix-Constrained Peptides Using Selenocysteine Crosslinking. Organic letters 20 (5) (2018)
Huimeng Wang, Criselle D'Souza, Xin Yi Lim, Lyudmila Kostenko, Troi J Pediongco, Sidonia Barbara Guiomar Eckle, Bronwyn S Meehan, Mai Shi, Nancy Wang, Shihan Li, Ligong Liu, Jeffrey Y W Mak, David P Fairlie, Yoichiro Iwakura, Jennifer M Gunnersen, Andrew W Stent, Dale I Godfrey, Jamie Rossjohn, Glen P Westall, Lars Kjer-Nielsen, Richard A Strugnell, James McCluskey, Alexandra J Corbett, Timothy Stopford Christopher Hinks, Zhenjun Chen
MAIT cells protect against pulmonary Legionella longbeachae infection. Nature communications 9 (1) (2018)
Daniel S Nielsen, Nicholas E Shepherd, Weijun Xu, Andrew J Lucke, Martin J Stoermer, David P Fairlie
Orally Absorbed Cyclic Peptides. Chemical reviews 117 (12) (2017)
Aline Dantas de Araujo, Chongyang Wu, Kai-Chen Wu, Robert C Reid, Thomas Durek, Junxian Lim, David P Fairlie
Europium-Labeled Synthetic C3a Protein as a Novel Fluorescent Probe for Human Complement C3a Receptor. Bioconjugate chemistry 28 (6) (2017)
Abishek Iyer, Weijun Xu, Robert C Reid, David P Fairlie
Chemical Approaches to Modulating Complement-Mediated Diseases. Journal of medicinal chemistry 61 (8) (2017)
Yuhong Jiang, Mei-Kwan Yau, W Mei Kok, Junxian Lim, Kai-Chen Wu, Ligong Liu, Timothy A Hill, Jacky Y Suen, David P Fairlie
Biased Signaling by Agonists of Protease Activated Receptor 2. ACS chemical biology 12 (5) (2017)
Michèle R Prinsep, Trevor G Appleton, Graeme R Hanson, Ian Lane, Charles D Smith, Jonathan Puddick, David P Fairlie
Tolyporphin Macrocycles from the Cyanobacterium Tolypothrix nodosa Selectively Bind Copper and Silver and Reverse Multidrug Resistance. Inorganic chemistry 56 (10) (2017)
Daniel Baxter, Samuel R Perry, Timothy A Hill, W Mei Kok, Nathan R Zaccai, R Leo Brady, David P Fairlie, Jody M Mason
Downsizing Proto-oncogene cFos to Short Helix-Constrained Peptides That Bind Jun. ACS chemical biology 12 (8) (2017)

David P Fairlie.css-eqlu8i{font-size:small;padding-left:4px;} (D P Fairlie)

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David P Fairlie (D P Fairlie)