Jean Sévigny

ResearcherID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2014-2023
Publications (10 Years): 18

Top Venues

Nature cell biology

Mediators of inflammation

RSC advances

International journal of molecular sciences

CHU de Québec-Université Laval

Université de Sherbrooke Faculté des Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

CHU de Québec-Université Laval Aug 01 2001

Canada

Senior Scientist

Université Laval Aug 01 2001

Canada

Professor :: Department of Microbiology-Infectiology and Immunology

Harvard Medical School

United States

Instructor in Medicine :: Gastroenterology

Education History

Université de Sherbrooke Faculté des Sciences Jan 06 1992

Canada

PHD :: Biology

Universite de Sherbrooke Faculté de médecine et des sciences de la santé May 10 1988 - Dec 15 1991

Canada

MSC :: Microbiology

Université de Sherbrooke Faculté des Sciences Sep 04 1985 - May 02 1988

Canada

BSC :: Biology

Publications

Xiaofeng Huang, Wei Gu, Jiaoyue Zhang, Ying Lan, Jonathan L Colarusso, Sanlan Li, Christoph Pertl, Jiaqi Lu, Hyunkee Kim, Jian Zhu, David T Breault, Jean Sévigny, Qiao Zhou
Stomach-derived human insulin-secreting organoids restore glucose homeostasis. Nature cell biology (2023)
Xiaofeng Huang, Wei Gu, Jiaoyue Zhang, Ying Lan, Jonathan L Colarusso, Sanlan Li, Christoph Pertl, Jiaqi Lu, Hyunkee Kim, Jian Zhu, David T Breault, Jean Sévigny, Qiao Zhou
Stomach-derived human insulin-secreting organoids restore glucose homeostasis. Nature cell biology 25 (5) (2023)
Xiaofeng Huang, Wei Gu, Jiaoyue Zhang, Ying Lan, Jonathan L Colarusso, Sanlan Li, Christoph Pertl, Jiaqi Lu, Hyunkee Kim, Jian Zhu, David T Breault, Jean Sévigny, Qiao Zhou
Stomach-derived human insulin-secreting organoids restore glucose homeostasis. Nature cell biology 25 (5) (2023)
Julie Favre, Charlotte Roy, Anne-Laure Guihot, Annick Drouin, Manon Laprise, Marc-Antoine Gillis, Simon C Robson, Eric Thorin, Jean Sévigny, Henrion Daniel, Gilles Kauffenstein
NTPDase1/CD39 Ectonucleotidase Is Necessary for Normal Arterial Diameter Adaptation to Flow. International journal of molecular sciences 24 (20) (2023)
Zahid Hussain Zaigham, Saif Ullah, Julie Pelletier, Jean Sévigny, Jamshed Iqbal, Abbas Hassan
Synthesis and biological evaluation of sulfamoyl benzamide derivatives as selective inhibitors for h -NTPDases. RSC advances 13 (30) (2023)
Muhammad Siraj Khan Jadoon, Julie Pelletier, Jean Sévigny, Jamshed Iqbal
Synthesis of new class of indole acetic acid sulfonate derivatives as ectonucleotidases inhibitors. RSC advances 13 (42) (2023)
Xiaofeng Huang, Wei Gu, Jiaoyue Zhang, Ying Lan, Jonathan L Colarusso, Sanlan Li, Christoph Pertl, Jiaqi Lu, Hyunkee Kim, Jian Zhu, David T Breault, Jean Sévigny, Qiao Zhou
Stomach-derived human insulin-secreting organoids restore glucose homeostasis. Nature cell biology 25 (5) (2023)
Chakib Hamoudi, Chenqi Zhao, Amna Abderrazak, Mabrouka Salem, Paul R Fortin, Jean Sévigny, Fawzi Aoudjit
The Purinergic Receptor P2X4 Promotes Th17 Activation and the Development of Arthritis. Journal of immunology (Baltimore, Md. : 1950) 208 (5) (2022)
Laura Schäkel, Salahuddin Mirza, Riekje Winzer, Vittoria Lopez, Riham Idris, Haneen Al-Hroub, Julie Pelletier, Jean Sévigny, Eva Tolosa, Christa Elisabeth Müller
Protein kinase inhibitor ceritinib blocks ectonucleotidase CD39 - a promising target for cancer immunotherapy. Journal for immunotherapy of cancer 10 (8) (2022)
Mabrouka Salem, Joanna Lecka, Julie Pelletier, Danielle Gomes Marconato, Aline Dumas, Luc Vallières, Gaetan Brochu, Bernard Robaye, Christian Jobin, Jean Sévigny
NTPDase8 protects mice from intestinal inflammation by limiting P2Y6 receptor activation: identification of a new pathway of inflammation for the potential treatment of IBD. Gut 71 (1) (2021)
Aitor Rodríguez-Martínez, Carla Trapero, August Vidal Bel, Josep Maria Piulats, Inmaculada Gómez de Aranda, Jean Sévigny, Maria Eulalia Fernández-Montolí, Jordi Ponce Sebastià, Xavier Matias-Guiu, Mireia Martín-Satué
Characterization of the Endometrial MSC Marker Ectonucleoside Triphosphate Diphosphohydrolase-2 (NTPDase2/CD39L1) in Low- and High-Grade Endometrial Carcinomas: Loss of Stromal Expression in the Invasive Phenotypes. Journal of personalized medicine 11 (5) (2021)
Vittoria Lopez, Laura Schäkel, H J Maximilian Schuh, Michael S Schmidt, Salahuddin Mirza, Christian Renn, Julie Pelletier, Sang-Yong Lee, Jean Sévigny, Susanne Alban, Gerd Bendas, Christa Elisabeth Müller
Sulfated Polysaccharides from Macroalgae Are Potent Dual Inhibitors of Human ATP-Hydrolyzing Ectonucleotidases NPP1 and CD39. Marine drugs 19 (2) (2021)
Romuald Brice Babou Kammoe, Gilles Kauffenstein, Julie Pelletier, Bernard Robaye, Jean Sévigny
NTPDase1 Modulates Smooth Muscle Contraction in Mice Bladder by Regulating Nucleotide Receptor Activation Distinctly in Male and Female. Biomolecules 11 (2) (2021)
Laura Schäkel, Salahuddin Mirza, Markus Pietsch, Sang-Yong Lee, Tim Keuler, Katharina Sylvester, Julie Pelletier, Jean Sévigny, Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam, Michael Gütschow, Christa Elisabeth Müller
2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors. Archiv der Pharmazie 354 (12) (2021)
Carina Herman-de-Sousa, Ana Rita Pinheiro, Diogo Paramos-de-Carvalho, Maria Adelina Costa, Fátima Ferreirinha, Teresa Magalhães-Cardoso, Severino Ribeiro, Julie Pelletier, Jean Sévigny, Steven N Ebert
Opposing Effects of Adenosine and Inosine in Human Subcutaneous Fibroblasts May Be Regulated by Third Party ADA Cell Providers. Cells 9 (3) (2020)
Julie Pelletier, Hervé Agonsanou, Fabiana Manica, Elise G Lavoie, Mabrouka Salem, Patrick Luyindula, Romuald Brice Babou Kammoe, Jean Sévigny
A Simple and Efficient Genetic Immunization Protocol for the Production of Highly Specific Polyclonal and Monoclonal Antibodies against the Native Form of Mammalian Proteins. International journal of molecular sciences 21 (19) (2020)
Hoang Huy Do, Saif Ullah, Alexander Villinger, Joanna Lecka, Jean Sévigny, Peter Ehlers, Jamshed Iqbal, Peter Langer
Palladium-catalyzed synthesis and nucleotide pyrophosphatase inhibition of benzo[4,5]furo[3,2-b]indoles. Beilstein journal of organic chemistry 15 (2019)
Veaceslav Boldescu, Natalia Sucman, Sidra Hassan, Jamshed Iqbal, Mariana Neamtu, Joanna Lecka, Jean Sévigny, Denis Prodius, Fliur Z Macaev
Ectonucleotidase Inhibitory and Redox Activity of Imidazole-Based Organic Salts and Ionic Liquids. ChemMedChem 13 (21) (2018)
Cátia Vieira, Maria Teresa Magalhães-Cardoso, Fátima Ferreirinha, Isabel Silva, Ana Sofia Dias, Julie Pelletier, Jean Sévigny, Steven N Ebert
Feed-forward inhibition of CD73 and upregulation of adenosine deaminase contribute to the loss of adenosine neuromodulation in postinflammatory ileitis. Mediators of inflammation 2014 (2014)
Joanna Lecka, Michel Fausther, Beat Künzli, Jean Sévigny
Ticlopidine in its prodrug form is a selective inhibitor of human NTPDase1. Mediators of inflammation 2014 (2014)

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Publication Activity (10 Years)

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Jean Sévigny