Vigneshwaran Namasivayam

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 31

Top Venues

Journal of medicinal chemistry

Science (New York, N.Y.)

Scientific data

RSC medicinal chemistry

University of Bonn

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Bonn Oct 01 2010

Germany

Senior Research Scientist :: Department of Pharmaceutical & Medicinal Chemsitry

Publications

Katja Stefan, Vigneshwaran Namasivayam, Sven Marcel Stefan
Computer-aided pattern scoring - A multitarget dataset-driven workflow to predict ligands of orphan targets. Scientific data 11 (1) (2024)
Katja Stefan, Vigneshwaran Namasivayam, Sven Marcel Stefan
Computer-aided pattern scoring - A multitarget dataset-driven workflow to predict ligands of orphan targets. Scientific data 11 (1) (2024)
Katja Stefan, Vigneshwaran Namasivayam, Sven Marcel Stefan
Computer-aided pattern scoring - A multitarget dataset-driven workflow to predict ligands of orphan targets. Scientific data 11 (1) (2024)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Murugesan Vanangamudi, Senthilkumar Palaniappan, Muthu Kumaradoss Kathiravan, Vigneshwaran Namasivayam
Strategies in the Design and Development of Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs). Viruses 15 (10) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Mariam Tahoun, Marianne Engeser, Vigneshwaran Namasivayam, Paul Martin Sander, Christa Elisabeth Müller
Chemistry and Analysis of Organic Compounds in Dinosaurs. Biology 11 (5) (2022)
Alexander Neumann, Isaac Attah, Haneen Al-Hroub, Vigneshwaran Namasivayam, Christa Elisabeth Müller
Discovery of P2Y 2 Receptor Antagonist Scaffolds through Virtual High-Throughput Screening. Journal of chemical information and modeling 62 (6) (2022)
Sandhya Chipurupalli, Raja Ganesan, Giulia Martini, Luigi Mele, Alessio Reggio, Marianna Esposito, Elango Kannan, Vigneshwaran Namasivayam, Paolo Grumati, Vincenzo Desiderio, Nirmal Robinson
Cancer cells adapt FAM134B/BiP mediated ER-phagy to survive hypoxic stress. Cell death & disease 13 (4) (2022)
Sven Marcel Stefan, Patric Jan Jansson, Jens Pahnke, Vigneshwaran Namasivayam
A curated binary pattern multitarget dataset of focused ATP-binding cassette transporter inhibitors. Scientific data 9 (1) (2022)
Stefanie Hagenow, Anna Affini, Elsa Y Pioli, Sonja Hinz, Yan Zhao, Gregory Porras, Vigneshwaran Namasivayam, Christa Elisabeth Müller, Jian-Sheng Lin, Erwan Bezard, Holger Stark
Adenosine A2AR/A1R Antagonists Enabling Additional H3R Antagonism for the Treatment of Parkinson's Disease. Journal of medicinal chemistry 64 (12) (2021)
Sang-Yong Lee, Vigneshwaran Namasivayam, Nader M Boshta, Arianna Perotti, Salahuddin Mirza, Silvia Bua, Claudiu T Supuran, Christa Elisabeth Müller
Discovery of potent nucleotide pyrophosphatase/phosphodiesterase3 (NPP3) inhibitors with ancillary carbonic anhydrase inhibition for cancer (immuno)therapy. RSC medicinal chemistry 12 (7) (2021)
Vigneshwaran Namasivayam, Katja Silbermann, Michael Wiese, Jens Pahnke, Sven Marcel Stefan
C@PA: Computer-Aided Pattern Analysis to Predict Multitarget ABC Transporter Inhibitors. Journal of medicinal chemistry 64 (6) (2021)
Christa Elisabeth Müller, Vigneshwaran Namasivayam
Recommended tool compounds and drugs for blocking P2X and P2Y receptors. Purinergic signalling (2021)
Cornelia Hermes, René Richarz, Daniel A Wirtz, Julian Patt, Wiebke Hanke, Stefan Kehraus, Jan Hendrik Voß, Jim Küppers, Tsubasa Ohbayashi, Vigneshwaran Namasivayam, Judith Alenfelder, Asuka Inoue, Peter Mergaert, Michael Gütschow, Christa Elisabeth Müller, Evi Kostenis, Gabriele M König, Max Cruesemann
Thioesterase-mediated side chain transesterification generates potent Gq signaling inhibitor FR900359. Nature communications 12 (1) (2021)
Julian Breidenbach, Carina Lemke, Thanigaimalai Pillaiyar, Laura Schäkel, Ghazl Al Hamwi, Miriam Diett, Robin Gedschold, Nina Geiger, Vittoria Lopez, Salahuddin Mirza, Vigneshwaran Namasivayam, Anke C Schiedel, Katharina Sylvester, Dominik Thimm, Christin Vielmuth, Lan Phuong Vu, Maria Zyulina, Jochen Bodem, Michael Gütschow, Christa Elisabeth Müller
Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors. Angewandte Chemie (International ed. in English) 60 (18) (2021)
Wiebke Hanke, Julian Patt, Judith Alenfelder, Jan H Voss, Mitja M Zdouc, Stefan Kehraus, Jung Bong Kim, Goran V Grujičić, Vigneshwaran Namasivayam, Raphael Reher, Christa Elisabeth Müller, Evi Kostenis, Max Cruesemann, Gabriele M König
Feature-Based Molecular Networking for the Targeted Identification of Gq-Inhibiting FR900359 Derivatives. Journal of natural products 84 (7) (2021)
Laura Schäkel, Salahuddin Mirza, Markus Pietsch, Sang-Yong Lee, Tim Keuler, Katharina Sylvester, Julie Pelletier, Jean Sévigny, Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam, Michael Gütschow, Christa Elisabeth Müller
2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors. Archiv der Pharmazie 354 (12) (2021)
Markus Kuschak, Vigneshwaran Namasivayam, Muhammad Rafehi, Jan Hendrik Voß, Jaspal Garg, Jonathan G Schlegel, Aliaa Abdelrahman, Stefan Kehraus, Raphael Reher, Jim Küppers, Katharina Sylvester, Sonja Hinz, Michaela Matthey, Daniela Wenzel, Bernd K Fleischmann, Alexander Pfeifer, Asuka Inoue, Michael Gütschow, Gabriele M König, Christa Elisabeth Müller
Cell-permeable high-affinity tracers for Gq proteins provide structural insights, reveal distinct binding kinetics and identify small molecule inhibitors. British journal of pharmacology 177 (8) (2020)
Alexander Neumann, Viktor Engel, Andhika B Mahardhika, Clara T Schoeder, Vigneshwaran Namasivayam, Katarzyna Kieć-Kononowicz, Christa Elisabeth Müller
Computational Investigations on the Binding Mode of Ligands for the Cannabinoid-Activated G Protein-Coupled Receptor GPR18. Biomolecules 10 (5) (2020)
Katja Silbermann, Jiyang Li, Vigneshwaran Namasivayam, Fabian Baltes, Gerd Bendas, Sven Marcel Stefan, Michael Wiese
Superior Pyrimidine Derivatives as Selective ABCG2 Inhibitors and Broad-Spectrum ABCB1, ABCC1, and ABCG2 Antagonists. Journal of medicinal chemistry 63 (18) (2020)
Meryem Köse, Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam, Elisabetta De Filippo, Katharina Sylvester, Trond Ulven, Ivar von Kügelgen, Christa Elisabeth Müller
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights. Journal of medicinal chemistry 63 (5) (2019)
Gaochan Wu, Tong Zhao, Dongwei Kang, Jian Zhang, Yuning Song, Vigneshwaran Namasivayam, Jacob Kongsted, Christophe Pannecouque, Erik De Clercq, Vasanthanathan Poongavanam, Xinyong Liu, Peng Zhan
Overview of Recent Strategic Advances in Medicinal Chemistry. Journal of medicinal chemistry 62 (21) (2019)
Jie Jiang, Catharina Julia Seel, Ahmed Temirak, Vigneshwaran Namasivayam, Antonella Arridu, Jakub Schabikowski, Younis Baqi, Sonja Hinz, Jörg Hockemeyer, Christa Elisabeth Müller
A2B Adenosine Receptor Antagonists with Picomolar Potency. Journal of medicinal chemistry 62 (8) (2019)
Katja Silbermann, Sven Marcel Stefan, Randa Elshawadfy, Vigneshwaran Namasivayam, Michael Wiese
Identification of Thienopyrimidine Scaffold as an Inhibitor of the ABC Transport Protein ABCC1 (MRP1) and Related Transporters Using a Combined Virtual Screening Approach. Journal of medicinal chemistry 62 (9) (2019)
Anna Junker, Christian Renn, Clemens Dobelmann, Vigneshwaran Namasivayam, Shanu Jain, Karolina Losenkova, Heikki Irjala, Sierra Duca, Ramachandran Balasubramanian, Saibal Chakraborty, Frederik Börgel, Herbert Zimmermann, Gennady G Yegutkin, Christa Elisabeth Müller, Kenneth A Jacobson
Structure-Activity Relationship of Purine and Pyrimidine Nucleotides as Ecto-5'-Nucleotidase (CD73) Inhibitors. Journal of medicinal chemistry 62 (7) (2019)
Vigneshwaran Namasivayam, Murugesan Vanangamudi, Victor G Kramer, Sonali Kurup, Peng Zhan, Xinyong Liu, Jacob Kongsted, Siddappa N Byrareddy
The Journey of HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitors (NNRTIs) from Lab to Clinic. Journal of medicinal chemistry 62 (10) (2018)
Younis Baqi, Thanigaimalai Pillaiyar, Aliaa Abdelrahman, Olesja Kaufmann, Samer Alshaibani, Muhammad Rafehi, Saman Ghasimi, Rhalid Akkari, Kirsten Ritter, Katharina Simon, Andreas Spinrath, Evi Kostenis, Qiang Zhao, Meryem Köse, Vigneshwaran Namasivayam, Christa Elisabeth Müller
3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17. Journal of medicinal chemistry 61 (18) (2018)
Michael K Krapf, Jennifer Gallus, Vigneshwaran Namasivayam, Michael Wiese
2,4,6-Substituted Quinazolines with Extraordinary Inhibitory Potency toward ABCG2. Journal of medicinal chemistry 61 (17) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Vigneshwaran Namasivayam