Thanigaimalai Pillaiyar

ResearcherID Loop profile Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Topics

Antiplatelet Therapy

Pluripotent Stem Cells

Respiratory Syndrome Coronavirus

Pulmonary Fibrosis

Top Venues

Journal of medicinal chemistry

Archiv der Pharmazie

ACS pharmacology & translational science

International journal of molecular sciences

This page only lists publications with an associated author ORCID identifier.

Publications

Alp Bayrak, Martyna Szpakowska, Valerie Dicenta, Manuel Counson, Alexander Rasch, Anne-Katrin Rohlfing, Andy Chevigné, Meinrad Gawaz, Stefan A Laufer, Thanigaimalai Pillaiyar
Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Journal of medicinal chemistry 67 (16) (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Correction to "Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity". ACS pharmacology & translational science 7 (4) (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. ACS pharmacology & translational science 7 (2) (2024)
Alp Bayrak, Martyna Szpakowska, Valerie Dicenta, Manuel Counson, Alexander Rasch, Anne-Katrin Rohlfing, Andy Chevigné, Meinrad Gawaz, Stefan A Laufer, Thanigaimalai Pillaiyar
Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Journal of medicinal chemistry (2024)
Alp Bayrak, Martyna Szpakowska, Valerie Dicenta, Manuel Counson, Alexander Rasch, Anne-Katrin Rohlfing, Andy Chevigné, Meinrad Gawaz, Stefan A Laufer, Thanigaimalai Pillaiyar
Novel Small-Molecule Atypical Chemokine Receptor 3 Agonists: Design, Synthesis, and Pharmacological Evaluation for Antiplatelet Therapy. Journal of medicinal chemistry 67 (16) (2024)
Angelo Oneto, Ghazl Al Hamwi, Laura Schäkel, Nadine Krüger, Katharina Sylvester, Marvin Petry, Rasha Abu Shamleh, Thanigaimalai Pillaiyar, Tobias Claff, Anke C Schiedel, Norbert Sträter, Michael Gütschow, Christa Elisabeth Müller
Nonpeptidic Irreversible Inhibitors of SARS-CoV-2 Main Protease with Potent Antiviral Activity. Journal of medicinal chemistry (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. ACS pharmacology & translational science 7 (2) (2024)
Philipp Flury, Julian Breidenbach, Nadine Krüger, Rabea Voget, Laura Schäkel, Yaoyao Si, Vesa Krasniqi, Sara Calistri, Matthias Olfert, Katharina Sylvester, Cheila Rocha, Raphael Ditzinger, Alexander Rasch, Stefan Pöhlmann, Thales Kronenberger, Antti Poso, Katharina Rox, Stefan A Laufer, Christa Elisabeth Müller, Michael Gütschow, Thanigaimalai Pillaiyar
Cathepsin-Targeting SARS-CoV-2 Inhibitors: Design, Synthesis, and Biological Activity. ACS pharmacology & translational science 7 (2) (2024)
Nadine Krüger, Thales Kronenberger, Hang Xie, Cheila Rocha, Stefan H Pöhlmann, Haixia Su, Yechun Xu, Stefan A Laufer, Thanigaimalai Pillaiyar
Discovery of Polyphenolic Natural Products as SARS-CoV-2 M pro Inhibitors for COVID-19. Pharmaceuticals (Basel, Switzerland) 16 (2) (2023)
Daniel Marx, Mohamed Wessam Alnouri, Sophie Clemens, Robin Gedschold, Yvonne Riedel, Ghazl Al Hamwi, Thanigaimalai Pillaiyar, Jörg Hockemeyer, Vigneshwaran Namasivayam, Christa Elisabeth Müller
Discovery of Potent Agonists for the Predominant Variant of the Orphan MAS-Related G Protein-Coupled Receptor X4 (MRGPRX4). Journal of medicinal chemistry (2023)
Thanigaimalai Pillaiyar, Monika Wozniak, Dayana Abboud, Alexander Rasch, Aenne-Dorothea Liebing, Antti Poso, Thales Kronenberger, Claudia Stäubert, Stefan A Laufer, Julien Hanson
Development of Ligands for the Super Conserved Orphan G Protein-Coupled Receptor GPR27 with Improved Efficacy and Potency. Journal of medicinal chemistry (2023)
Nina Geiger, Viktoria Diesendorf, Valeria Roll, Eva-Maria König, Helena Obernolte, Katherina Sewald, Julian Breidenbach, Thanigaimalai Pillaiyar, Michael Gütschow, Christa Elisabeth Müller, Jochen Bodem
Cell Type-Specific Anti-Viral Effects of Novel SARS-CoV-2 Main Protease Inhibitors. International journal of molecular sciences 24 (4) (2023)
Nina Geiger, Viktoria Diesendorf, Valeria Roll, Eva-Maria König, Helena Obernolte, Katherina Sewald, Julian Breidenbach, Thanigaimalai Pillaiyar, Michael Gütschow, Christa Elisabeth Müller, Jochen Bodem
Cell Type-Specific Anti-Viral Effects of Novel SARS-CoV-2 Main Protease Inhibitors. International journal of molecular sciences 24 (4) (2023)
Nina Geiger, Viktoria Diesendorf, Valeria Roll, Eva-Maria König, Helena Obernolte, Katherina Sewald, Julian Breidenbach, Thanigaimalai Pillaiyar, Michael Gütschow, Christa Elisabeth Müller, Jochen Bodem
Cell Type-Specific Anti-Viral Effects of Novel SARS-CoV-2 Main Protease Inhibitors. International journal of molecular sciences 24 (4) (2023)
Philipp Flury, Olga Eppler, Dieter Schollmeyer, Stefan A Laufer, Thanigaimalai Pillaiyar
2,2,2-Trifluoroethanol-mediated hydroarylation of fluorinated alkynes with indoles: Application to diindolylmethanes. Archiv der Pharmazie 355 (8) (2022)
Andhika B Mahardhika, Anastasiia Ressemann, Sarah E Kremers, Mariana S Gregório Castanheira, Clara T Schoeder, Christa Elisabeth Müller, Thanigaimalai Pillaiyar
Design, synthesis, and structure-activity relationships of diindolylmethane derivatives as cannabinoid CB 2 receptor agonists. Archiv der Pharmazie (2022)
Thanigaimalai Pillaiyar, Philipp Flury, Nadine Krüger, Haixia Su, Laura Schäkel, Elany Barbosa da Silva, Olga Eppler, Thales Kronenberger, Tianqing Nie, Stephanie Luedtke, Cheila Rocha, Katharina Sylvester, Marvin R I Petry, James H McKerrow, Antti Poso, Stefan Pöhlmann, Michael Gütschow, Anthony J O'Donoghue, Yechun Xu, Christa Elisabeth Müller, Stefan A Laufer
Small-Molecule Thioesters as SARS-CoV-2 Main Protease Inhibitors: Enzyme Inhibition, Structure-Activity Relationships, Antiviral Activity, and X-ray Structure Determination. Journal of medicinal chemistry 65 (13) (2022)
Alp Bayrak, Julien Hanson, Stefan A Laufer, Thanigaimalai Pillaiyar
Super-conserved receptors expressed in the brain: biology and medicinal chemistry efforts. Future medicinal chemistry 14 (12) (2022)
Alp Bayrak, Florian Mohr, Kyra Kolb, Martyna Szpakowska, Ekaterina Shevchenko, Valerie Dicenta, Anne-Katrin Rohlfing, Mark Kudolo, Tatu Pantsar, Marcel Günther, Agnieszka A Kaczor, Antti Poso, Andy Chevigné, Thanigaimalai Pillaiyar, Meinrad Gawaz, Stefan A Laufer
Discovery and Development of First-in-Class ACKR3/CXCR7 Superagonists for Platelet Degranulation Modulation. Journal of medicinal chemistry 65 (19) (2022)
Thanigaimalai Pillaiyar, Masoud Sedaghati, Andhika B Mahardhika, Lukas L Wendt, Christa Elisabeth Müller
Iodine-catalyzed electrophilic substitution of indoles: Synthesis of (un)symmetrical diindolylmethanes with a quaternary carbon center. Beilstein journal of organic chemistry 17 (2021)
Max Braune, Nico Scherf, Claudia Heine, Katja Sygnecka, Thanigaimalai Pillaiyar, Chiara Parravicini, Bernd Heimrich, Maria P Abbracchio, Christa Elisabeth Müller, Heike Franke
Involvement of GPR17 in Neuronal Fibre Outgrowth. International journal of molecular sciences 22 (21) (2021)
Manoj Manickam, Sangeetha Meenakshisundaram, Thanigaimalai Pillaiyar
Activating endogenous resolution pathways by soluble epoxide hydrolase inhibitors for the management of COVID-19. Archiv der Pharmazie (2021)
Julian Breidenbach, Carina Lemke, Thanigaimalai Pillaiyar, Laura Schäkel, Ghazl Al Hamwi, Miriam Diett, Robin Gedschold, Nina Geiger, Vittoria Lopez, Salahuddin Mirza, Vigneshwaran Namasivayam, Anke C Schiedel, Katharina Sylvester, Dominik Thimm, Christin Vielmuth, Lan Phuong Vu, Maria Zyulina, Jochen Bodem, Michael Gütschow, Christa Elisabeth Müller
Targeting the Main Protease of SARS-CoV-2: From the Establishment of High Throughput Screening to the Design of Tailored Inhibitors. Angewandte Chemie (International ed. in English) 60 (18) (2021)
Laura Schäkel, Salahuddin Mirza, Markus Pietsch, Sang-Yong Lee, Tim Keuler, Katharina Sylvester, Julie Pelletier, Jean Sévigny, Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam, Michael Gütschow, Christa Elisabeth Müller
2-Substituted thienotetrahydropyridine derivatives: Allosteric ectonucleotidase inhibitors. Archiv der Pharmazie 354 (12) (2021)
Thanigaimalai Pillaiyar, Stefan A Laufer
Kinases as Potential Therapeutic Targets for Anti-coronaviral Therapy. Journal of medicinal chemistry (2021)
Henrique A Esteves, Nicole McNamara, Oliver May, Thanigaimalai Pillaiyar, David C Blakemore, Steven V Ley
Photoredox Generation of Sulfonyl Radicals and Coupling with Electron Deficient Olefins. Organic letters 22 (15) (2020)
Thanigaimalai Pillaiyar, Masoud Sedaghati, Gregor Schnakenburg
Reaction of indoles with aromatic fluoromethyl ketones: an efficient synthesis of trifluoromethyl(indolyl)phenylmethanols using K2CO3/n-Bu4PBr in water. Beilstein journal of organic chemistry 16 (2020)
Thanigaimalai Pillaiyar, Lukas L Wendt, Manoj Manickam, Maheswaran Easwaran
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective. Medicinal research reviews 41 (1) (2020)
Meryem Köse, Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam, Elisabetta De Filippo, Katharina Sylvester, Trond Ulven, Ivar von Kügelgen, Christa Elisabeth Müller
An Agonist Radioligand for the Proinflammatory Lipid-Activated G Protein-Coupled Receptor GPR84 Providing Structural Insights. Journal of medicinal chemistry 63 (5) (2019)
Sangeetha Meenakshisundaram, Manoj Manickam, Thanigaimalai Pillaiyar
Exploration of imidazole and imidazopyridine dimers as anticancer agents: Design, synthesis, and structure-activity relationship study. Archiv der Pharmazie 352 (12) (2019)
Younis Baqi, Thanigaimalai Pillaiyar, Aliaa Abdelrahman, Olesja Kaufmann, Samer Alshaibani, Muhammad Rafehi, Saman Ghasimi, Rhalid Akkari, Kirsten Ritter, Katharina Simon, Andreas Spinrath, Evi Kostenis, Qiang Zhao, Meryem Köse, Vigneshwaran Namasivayam, Christa Elisabeth Müller
3-(2-Carboxyethyl)indole-2-carboxylic Acid Derivatives: Structural Requirements and Properties of Potent Agonists of the Orphan G Protein-Coupled Receptor GPR17. Journal of medicinal chemistry 61 (18) (2018)
Thanigaimalai Pillaiyar, Vigneshwaran Namasivayam, Manoj Manickam, Sang-Hun Jung
Inhibitors of Melanogenesis: An Updated Review. Journal of medicinal chemistry 61 (17) (2018)
Thanigaimalai Pillaiyar, Ewelina Gorska, Gregor Schnakenburg, Christa Elisabeth Müller
General Synthesis of Unsymmetrical 3,3'-(Aza)diindolylmethane Derivatives. The Journal of organic chemistry 83 (17) (2018)