Jianjun Cheng

ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 27

Top Venues

Journal of medicinal chemistry

Science (New York, N.Y.)

Nature communications

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology

ShanghaiTech University

Shanghai Institute of Materia Medica Chinese Academy of Sciences (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

ShanghaiTech University Mar 21 2016

China

Principal Investigator, Research Associate Professor :: iHuman Institute

University of Illinois at Chicago

United States

Postdoctoral Associate :: Medicinal Chemistry and Pharmacognosy

Education History

Shanghai Institute of Materia Medica Chinese Academy of Sciences Sep 01 2005 - Jul 01 2010

China

PHD :: Medicinal Chemistry

Publications

Wenwen Duan, Dongmei Cao, Sheng Wang, Jianjun Cheng
Serotonin 2A Receptor (5-HT 2A R) Agonists: Psychedelics and Non-Hallucinogenic Analogues as Emerging Antidepressants. Chemical reviews (2023)
Ruiquan Liu, Jianzhong Qi, Huan Wang, Luyu Fan, Pei Zhang, Jing Yu, Liang Tan, Sheng Wang, Jianjun Cheng
Transformation of a Dopamine D 2 Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents. Journal of medicinal chemistry (2023)
Nan Sun, Kexin Yang, Wenzhong Yan, Mingyue Yao, Chengcheng Yu, Wenwen Duan, Xiaoke Gu, Dong Guo, Hualiang Jiang, Chengying Xie, Jianjun Cheng
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response. Journal of medicinal chemistry (2023)
Jianhang Mao, Yilong Cui, Huan Wang, Wenwen Duan, Zhi-Jie Liu, Tian Hua, Ning Zhou, Jianjun Cheng
Design and Synthesis of Novel GPR139 Agonists with Therapeutic Effects in Mouse Models of Social Interaction and Cognitive Impairment. Journal of medicinal chemistry (2023)
Jinfeng Zhang, Dandan Feng, Jianjun Cheng, Kurt Wüthrich
Adenosine A 2A Receptor (A 2A AR) Ligand Screening Using the 19 F-NMR Probe FPPA. Journal of the American Chemical Society (2023)
Nan Sun, Kexin Yang, Wenzhong Yan, Mingyue Yao, Chengcheng Yu, Wenwen Duan, Xiaoke Gu, Dong Guo, Hualiang Jiang, Chengying Xie, Jianjun Cheng
Design and Synthesis of Triazole-Containing HDAC Inhibitors That Induce Antitumor Effects and Immune Response. Journal of medicinal chemistry (2023)
Ruiquan Liu, Jianzhong Qi, Huan Wang, Luyu Fan, Pei Zhang, Jing Yu, Liang Tan, Sheng Wang, Jianjun Cheng
Transformation of a Dopamine D 2 Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents. Journal of medicinal chemistry 66 (9) (2023)
Ruiquan Liu, Jianzhong Qi, Huan Wang, Luyu Fan, Pei Zhang, Jing Yu, Liang Tan, Sheng Wang, Jianjun Cheng
Transformation of a Dopamine D 2 Receptor Agonist to Partial Agonists as Novel Antipsychotic Agents. Journal of medicinal chemistry 66 (9) (2023)
Jingjing Wang, Meng Wu, Zhangcheng Chen, Lijie Wu, Tian Wang, Dongmei Cao, Huan Wang, Shenhui Liu, Yueming Xu, Fei Li, Junlin Liu, Na Chen, Suwen Zhao, Jianjun Cheng, Sheng Wang, Tian Hua
The unconventional activation of the muscarinic acetylcholine receptor M4R by diverse ligands. Nature communications 13 (1) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry (2022)
Dongmei Cao, Jing Yu, Huan Wang, Zhipu Luo, Xinyu Liu, Licong He, Jianzhong Qi, Luyu Fan, Lingjie Tang, Zhangcheng Chen, Jinsong Li, Jianjun Cheng, Sheng Wang
Structure-based discovery of nonhallucinogenic psychedelic analogs. Science (New York, N.Y.) 375 (6579) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry 66 (2) (2022)
Haoran Zhang, Wenzhong Yan, Yongzhan Sun, Haoxing Yuan, Limin Su, Xudong Cao, Peng Wang, Zhou Xu, Youhui Hu, Zhongjian Wang, Yinan Wang, Kequan Fu, Ying Sun, Yupeng Chen, Jianjun Cheng, Dong Guo
Long Residence Time at the Vasopressin V 2 Receptor Translates into Superior Inhibitory Effects in Ex Vivo and In Vivo Models of Autosomal Dominant Polycystic Kidney Disease. Journal of medicinal chemistry 65 (11) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry 66 (2) (2022)
Weixiu Xu, Li-Jie Wu, Shenhui Liu, Xiao Liu, Xiaoling Cao, Cui Zhou, Jinyi Zhang, You Fu, Yu Guo, Yiran Wu, Qiwen Tan, Ling Wang, Junlin Liu, Longquan Jiang, Zhongbo Fan, Yuan Pei, Jingyi Yu, Jianjun Cheng, Suwen Zhao, Xiaojiang Hao, Zhi-Jie Liu, Tian Hua
Structural basis for strychnine activation of human bitter taste receptor TAS2R46. Science (New York, N.Y.) 377 (6612) (2022)
Xiaoke Gu, Haoxing Yuan, Wenchao Zhao, Nan Sun, Wenzhong Yan, Chunyu Jiang, Yan He, Hongli Liu, Jianjun Cheng, Dong Guo
Optical-Controlled Kinetic Switch: Fine-Tuning of the Residence Time of an Antagonist Binding to the Vasopressin V 2 Receptor in In Vitro , Ex Vivo, and In Vivo Models of ADPKD. Journal of medicinal chemistry 66 (2) (2022)
Wenzhong Yan, Lijun Ling, Yiran Wu, Kexin Yang, Ruiquan Liu, Jinfeng Zhang, Simeng Zhao, Guisheng Zhong, Suwen Zhao, Hualiang Jiang, Chengying Xie, Jianjun Cheng
Structure-Based Design of Dual-Acting Compounds Targeting Adenosine A2A Receptor and Histone Deacetylase as Novel Tumor Immunotherapeutic Agents. Journal of medicinal chemistry 64 (22) (2021)
Zhangcheng Chen, Luyu Fan, Huan Wang, Jing Yu, Dengyu Lu, Jianzhong Qi, Fen Nie, Zhipu Luo, Zhen Liu, Jianjun Cheng, Sheng Wang
Structure-based design of a novel third-generation antipsychotic drug lead with potential antidepressant properties. Nature neuroscience (2021)
Wenzhong Yan, Luyu Fan, Jing Yu, Ruiquan Liu, Huan Wang, Liang Tan, Sheng Wang, Jianjun Cheng
2-Phenylcyclopropylmethylamine Derivatives as Dopamine D2 Receptor Partial Agonists: Design, Synthesis, and Biological Evaluation. Journal of medicinal chemistry 64 (23) (2021)
Luyu Fan, Liang Tan, Zhangcheng Chen, Jianzhong Qi, Fen Nie, Zhipu Luo, Jianjun Cheng, Sheng Wang
Haloperidol bound D2 dopamine receptor structure inspired the discovery of subtype selective ligands. Nature communications 11 (1) (2020)
Liang Tan, Qingtong Zhou, Wenzhong Yan, Jian Sun, Alan P Kozikowski, Suwen Zhao, Xi-Ping Huang, Jianjun Cheng
Design and Synthesis of Bitopic 2-Phenylcyclopropylmethylamine (PCPMA) Derivatives as Selective Dopamine D3 Receptor Ligands. Journal of medicinal chemistry 63 (9) (2020)
Jinfeng Zhang, Wenzhong Yan, Wenwen Duan, Kurt Wüthrich, Jianjun Cheng
Tumor Immunotherapy Using A2A Adenosine Receptor Antagonists. Pharmaceuticals (Basel, Switzerland) 13 (9) (2020)
Deyu Kong, Tao Xue, Bin Guo, Jianjun Cheng, Shunying Liu, Jianhai Wei, Zhengyu Lu, Haoran Liu, Guoqing Gong, Tian Lan, Wenhao Hu, Yushe Yang
Optimization of P2Y12 Antagonist Ethyl 6-(4-((Benzylsulfonyl)carbamoyl)piperidin-1-yl)-5-cyano-2-methylnicotinate (AZD1283) Led to the Discovery of an Oral Antiplatelet Agent with Improved Druglike Properties. Journal of medicinal chemistry 62 (6) (2019)
Ming Zhao, Jianjun Cheng, Brian Guo, Jinao Duan, Chun-Tao Che
Momilactone and Related Diterpenoids as Potential Agricultural Chemicals. Journal of agricultural and food chemistry 66 (30) (2018)
Liang Tan, Wenzhong Yan, John D McCorvy, Jianjun Cheng
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential. Journal of medicinal chemistry 61 (22) (2018)
Vladimir M Pogorelov, Ramona M Rodriguiz, Jianjun Cheng, Mei Huang, Claire M Schmerberg, Herbert Y Meltzer, Bryan L Roth, Alan P Kozikowski, William C Wetsel
5-HT2C Agonists Modulate Schizophrenia-Like Behaviors in Mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 42 (11) (2017)
Guiping Zhang, Jianjun Cheng, John D McCorvy, Paul J Lorello, Barbara J Caldarone, Bryan L Roth, Alan P Kozikowski
Discovery of N-Substituted (2-Phenylcyclopropyl)methylamines as Functionally Selective Serotonin 2C Receptor Agonists for Potential Use as Antipsychotic Medications. Journal of medicinal chemistry 60 (14) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Jianjun Cheng