Johann-Christoph Jann (Johann C Jann)

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 24

Top Topics

Acute Myeloid Leukemia

Allogeneic Hematopoietic Stem Cell Transplantation

Top Venues

Nature genetics

Science translational medicine

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics 56 (6) (2024)
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics (2024)
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics 56 (6) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Johann-Christoph Jann, Christopher B Hergott, Marisa Winkler, Yiwen Liu, Benjamin Braun, Anne Charles, Kevin M Copson, Shougat Barua, Manja Meggendorfer, Niroshan Nadarajah, Shai Shimony, Eric S Winer, Martha Wadleigh, Richard M Stone, Daniel J DeAngelo, Jacqueline S Garcia, Torsten Haferlach, R Coleman Lindsley, Marlise R Luskin, Maximilian Stahl, Zuzana Tothova
Subunit-specific analysis of cohesin-mutant myeloid malignancies reveals distinct ontogeny and outcomes. Leukemia 38 (9) (2024)
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics 56 (6) (2024)
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics 56 (6) (2024)
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics 56 (6) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Johann-Christoph Jann, Christopher B Hergott, Marisa Winkler, Yiwen Liu, Benjamin Braun, Anne Charles, Kevin M Copson, Shougat Barua, Manja Meggendorfer, Niroshan Nadarajah, Shai Shimony, Eric S Winer, Martha Wadleigh, Richard M Stone, Daniel J DeAngelo, Jacqueline S Garcia, Torsten Haferlach, R Coleman Lindsley, Marlise R Luskin, Maximilian Stahl, Zuzana Tothova
Subunit-specific analysis of cohesin-mutant myeloid malignancies reveals distinct ontogeny and outcomes. Leukemia 38 (9) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Johann-Christoph Jann, Christopher B Hergott, Marisa Winkler, Yiwen Liu, Benjamin Braun, Anne Charles, Kevin M Copson, Shougat Barua, Manja Meggendorfer, Niroshan Nadarajah, Shai Shimony, Eric S Winer, Martha Wadleigh, Richard M Stone, Daniel J DeAngelo, Jacqueline S Garcia, Torsten Haferlach, R Coleman Lindsley, Marlise R Luskin, Maximilian Stahl, Zuzana Tothova
Subunit-specific analysis of cohesin-mutant myeloid malignancies reveals distinct ontogeny and outcomes. Leukemia 38 (9) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Karen Grimes, Hyobin Jeong, Amanda Amoah, Nuo Xu, Julian Niemann, Benjamin Raeder, Patrick Hasenfeld, Catherine Stober, Tobias Rausch, Eva Benito, Johann-Christoph Jann, Daniel Nowak, Ramiz Emini, Markus Hoenicka, Andreas Liebold, Anthony Dick Ho, Shimin Shuai, Hartmut Geiger, Ashley D Sanders, Jan O Korbel
Cell-type-specific consequences of mosaic structural variants in hematopoietic stem and progenitor cells. Nature genetics (2024)
Johann-Christoph Jann, Christopher B Hergott, Marisa Winkler, Yiwen Liu, Benjamin Braun, Anne Charles, Kevin M Copson, Shougat Barua, Manja Meggendorfer, Niroshan Nadarajah, Shai Shimony, Eric S Winer, Martha Wadleigh, Richard M Stone, Daniel J DeAngelo, Jacqueline S Garcia, Torsten Haferlach, R Coleman Lindsley, Marlise R Luskin, Maximilian Stahl, Zuzana Tothova
Subunit-specific analysis of cohesin-mutant myeloid malignancies reveals distinct ontogeny and outcomes. Leukemia (2024)
Hyobin Jeong, Karen Grimes, Kerstin K Rauwolf, Peter-Martin Bruch, Tobias Rausch, Patrick Hasenfeld, Eva Benito, Tobias Roider, Radhakrishnan Sabarinathan, David Porubsky, Sophie A Herbst, Büşra Erarslan-Uysal, Johann-Christoph Jann, Tobias Marschall, Daniel Nowak, Jean-Pierre Bourquin, Andreas E Kulozik, Sascha Dietrich, Beat C Bornhauser, Ashley D Sanders, Jan O Korbel
Functional analysis of structural variants in single cells using Strand-seq. Nature biotechnology (2022)
Johann-Christoph Jann, Maximilian Mossner, Vladimir Riabov, Eva Altrock, Nanni Schmitt, Johanna Flach, Qingyu Xu, Verena Nowak, Julia Obländer, Iris Palme, Nadine Weimer, Alexander Streuer, Ahmed Jawhar, Ali Darwich, Mohammad Jawhar, Georgia Metzgeroth, Florian Nolte, Wolf-Karsten Hofmann, Daniel Nowak
Bone marrow derived stromal cells from myelodysplastic syndromes are altered but not clonally mutated in vivo. Nature communications 12 (1) (2021)
Johann-Christoph Jann, Zuzana Tothova
Cohesin mutations in myeloid malignancies. Blood 138 (8) (2021)
Lars Velten, Benjamin A Story, Pablo Hernández-Malmierca, Simon Raffel, Daniel R Leonce, Jennifer Milbank, Malte Paulsen, Aykut Demir, Chelsea Szu-Tu, Robert Frömel, Christoph Lutz, Daniel Nowak, Johann-Christoph Jann, Caroline Pabst, Tobias Boch, Wolf-Karsten Hofmann, Carsten Muller-Tidow, Flavia Carla Meotti, Simon Haas, Lars M Steinmetz
Identification of leukemic and pre-leukemic stem cells by clonal tracking from single-cell transcriptomics. Nature communications 12 (1) (2021)
Sergio Triana, Dominik Vonficht, Lea Jopp-Saile, Simon Raffel, Raphael Lutz, Daniel Leonce, Magdalena Antes, Pablo Hernández-Malmierca, Diana Ordoñez-Rueda, Beáta Ramasz, Tobias Boch, Johann-Christoph Jann, Daniel Nowak, Wolf-Karsten Hofmann, Carsten Muller-Tidow, Daniel Hübschmann, Theodore Alexandrov, Vladimir Benes, Andreas Trumpp, Malte Paulsen, Lars Velten, Simon Haas
Single-cell proteo-genomic reference maps of the hematopoietic system enable the purification and massive profiling of precisely defined cell states. Nature immunology 22 (12) (2021)
Johann-Christoph Jann, Alexander Streuer, Anna Hecht, Florian Nolte, Verena Nowak, Justine Danner, Julia Obländer, Iris Palme, Eva Lengfelder, Uwe Platzbecker, Wolf-Karsten Hofmann, Johanna Flach, Daniel Nowak
RNA-sequencing of acute promyelocytic leukemia primary blasts reveals novel molecular biomarkers of early death events. Leukemia & lymphoma 61 (13) (2020)