Karen Adelman

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 33

Top Venues

Science (New York, N.Y.)

Science translational medicine

Research square

Nature communications

Harvard Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Harvard Medical School Aug 16 2016

United States

Professor :: Biological Chemistry and Molecular Pharmacology

National Institutes of Health

United States

Investigator :: NIEHS, Epigenetics ans Stem Cell Biology Laboratory

Publications

Nathan Lack, Umut Berkay Altintas, Ji-Heu Seo, Claudia Giambartolomei, Dogancan Ozturan, Brad Fortunato, Geoffrey M Nelson, Seth Goldman, Karen Adelman, Faraz Hach, Matthew Freedman
Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription. Research square (2024)
Alexander Tarakhovsky, Tuo Zhang, Ryan J Marina, Sarah Veugelen, Pal Mander, Rabinder K Prinjha, Anne Schaefer, Karen Adelman
The signaling cascade of induction and maintenance of ES cell diapause. Research square (2024)
Emily G Kaye, Kavyashree Basavaraju, Geoffrey M Nelson, Helena D Zomer, Debarun Roy, Irene Infancy Joseph, Reza Rajabi-Toustani, Huanyu Qiao, Karen Adelman, Prabhakara P Reddi
RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis. Nature communications 15 (1) (2024)
Nathan Lack, Umut Berkay Altintas, Ji-Heu Seo, Claudia Giambartolomei, Dogancan Ozturan, Brad Fortunato, Geoffrey M Nelson, Seth Goldman, Karen Adelman, Faraz Hach, Matthew Freedman
Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription. Research square (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily G Kaye, Kavyashree Basavaraju, Geoffrey M Nelson, Helena D Zomer, Debarun Roy, Irene Infancy Joseph, Reza Rajabi-Toustani, Huanyu Qiao, Karen Adelman, Prabhakara P Reddi
RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis. Nature communications 15 (1) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily G Kaye, Kavyashree Basavaraju, Geoffrey M Nelson, Helena D Zomer, Debarun Roy, Irene Infancy Joseph, Reza Rajabi-Toustani, Huanyu Qiao, Karen Adelman, Prabhakara P Reddi
RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis. Nature communications 15 (1) (2024)
Nathan Lack, Umut Berkay Altintas, Ji-Heu Seo, Claudia Giambartolomei, Dogancan Ozturan, Brad Fortunato, Geoffrey M Nelson, Seth Goldman, Karen Adelman, Faraz Hach, Matthew Freedman
Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription. Research square (2024)
Emily G Kaye, Kavyashree Basavaraju, Geoffrey M Nelson, Helena D Zomer, Debarun Roy, Irene Infancy Joseph, Reza Rajabi-Toustani, Huanyu Qiao, Karen Adelman, Prabhakara P Reddi
RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis. Nature communications 15 (1) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Nathan Lack, Umut Berkay Altintas, Ji-Heu Seo, Claudia Giambartolomei, Dogancan Ozturan, Brad Fortunato, Geoffrey M Nelson, Seth Goldman, Karen Adelman, Faraz Hach, Matthew Freedman
Decoding the Epigenetics and Chromatin Loop Dynamics of Androgen Receptor-Mediated Transcription. Research square (2024)
Emily G Kaye, Kavyashree Basavaraju, Geoffrey M Nelson, Helena D Zomer, Debarun Roy, Irene Infancy Joseph, Reza Rajabi-Toustani, Huanyu Qiao, Karen Adelman, Prabhakara P Reddi
RNA polymerase II pausing is essential during spermatogenesis for appropriate gene expression and completion of meiosis. Nature communications 15 (1) (2024)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Gongwei Wu, Noriaki Yoshida, Jihe Liu, Xiaoyang Zhang, Yuan Xiong, Tayla B Heavican-Foral, Elisa Mandato, Huiyun Liu, Geoffrey M Nelson, Lu Yang, Renee Chen, Katherine Aleisha Donovan, Marcus Kenneth Jones, Mikhail Roshal, Yanming Zhang, Ran Xu, Ajit J Nirmal, Salvia Jain, Catharine Leahy, Kristen L Jones, Kristen E Stevenson, Natasha Galasso, Nivetha Ganesan, Tiffany Chang, Wen-Chao Wu, Abner Louissaint, Lydie Debaize, Hojong Yoon, Paola Dal Cin, Wing C Chan, Shannan Ho Sui, Samuel Y Ng, Andrew L Feldman, Steven M Horwitz, Karen Adelman, Eric S Fischer, Chun-Wei David Chen, David M Weinstock, Myles A Brown
TP63 fusions drive multicomplex enhancer rewiring, lymphomagenesis, and EZH2 dependence. Science translational medicine 15 (714) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Megan L Insco, Brian J Abraham, Sara J Dubbury, Ines H Kaltheuner, Sofia Dust, Constance Wu, Kevin Y Chen, David R Liu, Stanislav Bellaousov, Anna M Cox, Benjamin J E Martin, Tongwu Zhang, Calvin Gerald Ludwig, Tania Fabo, Rodsy Modhurima, Dakarai E Esgdaille, Telmo Henriques, Kevin K Brown, Stephen J Chanock, Matthias Geyer, Karen Adelman, Phillip A Sharp, Richard A Young, Paul L Boutz, Leonard I Zon
Oncogenic CDK13 mutations impede nuclear RNA surveillance. Science (New York, N.Y.) 380 (6642) (2023)
Karen Adelman
Nascent transcription as a predictor and driver of histone modifications. Nature genetics 54 (3) (2022)
Hanneke Vlaming, Claudia A Mimoso, Andrew R Field, Benjamin J E Martin, Karen Adelman
Screening thousands of transcribed coding and non-coding regions reveals sequence determinants of RNA polymerase II elongation potential. Nature structural & molecular biology 29 (6) (2022)
Haining Zhou, Chad B Stein, Tiasha A Shafiq, Gergana Shipkovenska, Marian Kalocsay, Joao A Paulo, Jiuchun Zhang, Zhenhua Luo, Steven P Gygi, Karen Adelman, Danesh Moazed
Rixosomal RNA degradation contributes to silencing of Polycomb target genes. Nature 604 (7904) (2022)
Katerina Cermakova, Jonas Demeulemeester, Vanda Lux, Monika Nedomova, Seth R Goldman, Eric A Smith, Pavel Srb, Rozalie Hexnerova, Milan Fabry, Marcela Madlikova, Magdalena Horejsi, Jan De Rijck, Zeger Debyser, Karen Adelman, H Courtney Hodges, Vaclav Veverka
A ubiquitous disordered protein interaction module orchestrates transcription elongation. Science (New York, N.Y.) 374 (6571) (2021)
Julia M Rogers, Bingqian Guo, Emily D Egan, Jon C Aster, Karen Adelman, Stephen C Blacklow
MAML1-Dependent Notch-Responsive Genes Exhibit Differing Cofactor Requirements for Transcriptional Activation. Molecular and cellular biology 40 (11) (2020)
Michael P Meers, Telmo Henriques, Christopher A Lavender, Daniel J McKay, Brian D Strahl, Robert J Duronio, Karen Adelman, A Gregory Matera
Histone gene replacement reveals a post-transcriptional role for H3K36 in maintaining metazoan transcriptome fidelity. eLife 6 (2017)
Athma A Pai, Telmo Henriques, Kayla McCue, Adam Burkholder, Karen Adelman, Christopher B Burge
The kinetics of pre-mRNA splicing in the Drosophila genome and the influence of gene architecture. eLife 6 (2017)

Karen Adelman.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Karen Adelman