Yana Pikman

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 28

Top Topics

Acute Myeloid Leukemia

Gene Expression

Top Venues

Science translational medicine

Cancer discovery

This page only lists publications with an associated author ORCID identifier.

Publications

Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid, Yana Pikman, Angelika Amon, Michael T Hemann, R Grant Rowe
Inherent genome instability underlies trisomy 21-associated myeloid malignancies. Leukemia 38 (3) (2024)
Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid, Yana Pikman, Angelika Amon, Michael T Hemann, R Grant Rowe
Inherent genome instability underlies trisomy 21-associated myeloid malignancies. Leukemia 38 (3) (2024)
Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid, Yana Pikman, Angelika Amon, Michael T Hemann, R Grant Rowe
Inherent genome instability underlies trisomy 21-associated myeloid malignancies. Leukemia 38 (3) (2024)
Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid, Yana Pikman, Angelika Amon, Michael T Hemann, R Grant Rowe
Inherent genome instability underlies trisomy 21-associated myeloid malignancies. Leukemia 38 (3) (2024)
Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid, Yana Pikman, Angelika Amon, Michael T Hemann, R Grant Rowe
Inherent genome instability underlies trisomy 21-associated myeloid malignancies. Leukemia 38 (3) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Chun-Chin Chen, Rebecca E Silberman, Duanduan Ma, Jennifer A Perry, Delan Khalid, Yana Pikman, Angelika Amon, Michael T Hemann, R Grant Rowe
Inherent genome instability underlies trisomy 21-associated myeloid malignancies. Leukemia (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Jonathan D Paolino, Harrison K Tsai, Marian H Harris, Yana Pikman
IKZF1 Alterations and Therapeutic Targeting in B-Cell Acute Lymphoblastic Leukemia. Biomedicines 12 (1) (2024)
Emily C Wheeler, Benjamin J E Martin, William C Doyle, Sofia Neaher, Caroline A Conway, Caroline N Pitton, Rebecca A Gorelov, Melanie Donahue, Johann-Christoph Jann, Omar Abdel-Wahab, Justin Taylor, Michael Seiler, Silvia Buonamici, Yana Pikman, Jacqueline S Garcia, Roger Belizaire, Karen Adelman, Zuzana Tothova
Splicing modulators impair DNA damage response and induce killing of cohesin-mutant MDS and AML. Science translational medicine 16 (728) (2024)
Jonathan D Paolino, Harrison K Tsai, Marian H Harris, Yana Pikman
IKZF1 Alterations and Therapeutic Targeting in B-Cell Acute Lymphoblastic Leukemia. Biomedicines 12 (1) (2024)
Wallace Bourgeois, Jevon A Cutler, Brandon J Aubrey, Daniela V Wenge, Florian Perner, Cynthia Martucci, Jill A Henrich, Kelly S Klega, Radosław P Nowak, Katherine Aleisha Donovan, Meaghan Boileau, Yanhe Wen, Charles Hatton, Athina A Apazidis, Sarah Naomi Olsen, Nadia Kirmani, Yana Pikman, Jessica A Pollard, Jennifer A Perry, Adam S Sperling, Benjamin L Ebert, Gerard M McGeehan, Brian D Crompton, Eric S Fischer, Scott A Armstrong
Mezigdomide is effective alone and in combination with Menin inhibition in pre-clinical models of KMT2A-r and NPM1c AML. Blood (2023)
Jonathan D Paolino, Boris Dimitrov, Beth Apsel Winger, Angélica Sandoval-Pérez, Amith Vikram Rangarajan, Nicole Ocasio-Martinez, Harrison K Tsai, Yuting Li, Amanda L Robichaud, Delan Khalid, Charles Hatton, Riaz Gillani, Petri Polonen, Anthony Dilig, Giacomo Gotti, Julia Kavanagh, Asmani A Adhav, Sean Gow, Jonathan M Tsai, Yen-Der Li, Benjamin L Ebert, Eliezer Van Allen, Jacob R Bledsoe, Annette S Kim, Sarah K Tasian, Stacy L Cooper, Todd M Cooper, Nobuko Hijiya, Maria-Luisa Sulis, Neerav N Shukla, Jeffrey A Magee, Charles G Mullighan, Michael J Burke, Marlise R Luskin, Brenton G Mar, Matthew P Jacobson, Marian H Harris, Kimberly Stegmaier, Andrew E Place, Yana Pikman
Integration of genomic sequencing drives therapeutic targeting of PDGFRA in T-cell acute lymphoblastic leukemia/lymphoblastic lymphoma. Clinical cancer research : an official journal of the American Association for Cancer Research (2023)
Jana M Ellegast, Gabriela Alexe, Amanda Hamze, Shan Lin, Hannah J Uckelmann, Philipp J Rauch, Maxim Pimkin, Linda S Ross, Neekesh V Dharia, Amanda L Robichaud, Amy Saur Conway, Delan Khalid, Jennifer A Perry, Mark Wunderlich, Lina Benajiba, Yana Pikman, Behnam Nabet, Nathanael S Gray, Stuart H Orkin, Kimberly Stegmaier
Unleashing Cell-Intrinsic Inflammation as a Strategy to Kill AML Blasts. Cancer discovery 12 (7) (2022)
Rahela Aziz-Bose, Franziska Wachter, Roberto Chiarle, Neal I Lindeman, Annette S Kim, Barbara A Degar, Kimberly Davies, Yana Pikman
Rapid next-generation sequencing aids in diagnosis of transient abnormal myelopoiesis in a phenotypically normal newborn. Blood advances 6 (9) (2022)
Brandon J Aubrey, Jevon A Cutler, Wallace Bourgeois, Katherine A Donovan, Shengqing Gu, Charles Hatton, Sarah Perlee, Florian Perner, Homa Rahnamoun, Alexandra C P Theall, Jill A Henrich, Qian Zhu, Radosław P Nowak, Young Joon Kim, Salma Parvin, Anjali Cremer, Sarah Naomi Olsen, Nicholas A Eleuteri, Yana Pikman, Gerard M McGeehan, Kimberly Stegmaier, Anthony G Letai, Eric S Fischer, X Shirley Liu, Scott A Armstrong
IKAROS and MENIN coordinate therapeutically actionable leukemogenic gene expression in MLL-r acute myeloid leukemia. Nature cancer 3 (5) (2022)
Blandine Roux, Camille Vaganay, Jesse D Vargas, Gabriela Alexe, Chaima Benaksas, Bryann Pardieu, Nina Fenouille, Jana M Ellegast, Edyta Malolepsza, Frank Ling, Gaetano Sodaro, Linda Ross, Yana Pikman, Amy Saur Conway, Yangzhong Tang, Tony Wu, Daniel J Anderson, Ronan Le Moigne, Han-Jie Zhou, Frédéric Luciano, Christina R Hartigan, Ilene Galinsky, Daniel J DeAngelo, Richard M Stone, Patrick Auberger, Monica Schenone, Steven A Carr, Josée Guirouilh-Barbat, Bernard S Lopez, Mehdi Khaled, Kasper Lage, Olivier Hermine, Michael T Hemann, Alexandre Puissant, Kimberly Stegmaier, Lina Benajiba
Targeting acute myeloid leukemia dependency on VCP-mediated DNA repair through a selective second-generation small-molecule inhibitor. Science translational medicine 13 (587) (2021)
Emily B Heikamp, Jill A Henrich, Florian Perner, Eric M Wong, Charles Hatton, Yanhe Wen, Sonali P Barwe, Anilkumar Gopalakrishnapillai, Haiming Xu, Hannah Julia Uckelmann, Sumiko Takao, Yaniv Kazansky, Yana Pikman, Gerard M McGeehan, Edward A Kolb, Alex Kentsis, Scott A Armstrong
The Menin-MLL1 interaction is a molecular dependency in NUP98-rearranged AML. Blood (2021)
Yana Pikman, Nicole Ocasio-Martinez, Gabriela Alexe, Boris Dimitrov, Samuel Kitara, Frances F Diehl, Amanda L Robichaud, Amy Saur Conway, Linda Ross, Angela Su, Frank Ling, Jun Qi, Giovanni Roti, Caroline A Lewis, Alexandre Puissant, Matthew G Vander Heiden, Kimberly Stegmaier
Targeting serine hydroxymethyltransferases 1 and 2 for T-cell acute lymphoblastic leukemia therapy. Leukemia (2021)
Yana Pikman, Sarah K Tasian, Maria Luisa Sulis, Kristen Stevenson, Traci M Blonquist, Beth Apsel Winger, Todd M Cooper, Melinda G Pauly, Kelly W Maloney, Michael J Burke, Patrick A Brown, Nathan Gossai, Jennifer L McNeer, Neerav N Shukla, Peter D Cole, Justine M Kahn, Jing Chen, Matthew J Barth, Jeffrey A Magee, Lisa Gennarini, Asmani A Adhav, Catherine M Clinton, Nicole Ocasio-Martinez, Giacomo Gotti, Yuting Li, Shan Lin, Alma Imamovic, Cristina E Tognon, Tasleema Patel, Haley L Faust, Cristina F Contreras, Anjali Cremer, Wilian A Cortopassi, Diego Garrido Ruiz, Matthew P Jacobson, Neekesh V Dharia, Angela Su, Amanda L Robichaud, Amy Saur Conway, Katherine Tarlock, Elliot Stieglitz, Andrew E Place, Alexandre Puissant, Stephen P Hunger, Annette S Kim, Neal I Lindeman, Lia Gore, Katherine A Janeway, Lewis B Silverman, Jeffrey W Tyner, Marian H Harris, Mignon L Loh, Kimberly Stegmaier
Matched Targeted Therapy for Pediatric Patients with Relapsed, Refractory, or High-Risk Leukemias: A Report from the LEAP Consortium. Cancer discovery 11 (6) (2021)
Angela Su, Frank Ling, Camille Vaganay, Gaetano Sodaro, Chaïma Benaksas, Reinaldo Dal Bello, Antoine Forget, Bryann Pardieu, Kevin H Lin, Justine C Rutter, Christopher F Bassil, Gael Fortin, Justine Pasanisi, Iléana Antony-Debré, Gabriela Alexe, Jean-François Benoist, Alain Pruvost, Yana Pikman, Jun Qi, Marie-Hélène Schlageter, Jean-Baptiste Micol, Giovanni Roti, Thomas Cluzeau, Hervé Dombret, Claude Preudhomme, Nina Fenouille, Lina Benajiba, Hava M Golan, Kimberly Stegmaier, Camille Lobry, Kris C Wood, Raphael Itzykson, Alexandre Puissant
The Folate Cycle Enzyme MTHFR Is a Critical Regulator of Cell Response to MYC-Targeting Therapies. Cancer discovery 10 (12) (2020)
Anjali Cremer, Jana M Ellegast, Gabriela Alexe, Elizabeth S Frank, Linda Ross, S Haihua Chu, Yana Pikman, Amanda Robichaud, Amy Goodale, Björn Häupl, Sebastian Mohr, Arati V Rao, Alison R Walker, James S Blachly, Federica Piccioni, Scott A Armstrong, John C Byrd, Thomas Oellerich, Kimberly Stegmaier
Resistance Mechanisms to SYK Inhibition in Acute Myeloid Leukemia. Cancer discovery 10 (2) (2019)
Florence F Wagner, Lina Benajiba, Arthur J Campbell, Michel Weïwer, Joshua R Sacher, Jennifer P Gale, Linda Ross, Alexandre Puissant, Gabriela Alexe, Amy Saur Conway, Morgan Back, Yana Pikman, Ilene Galinsky, Daniel J DeAngelo, Richard M Stone, Taner Kaya, Xi Shi, Matthew B Robers, Thomas Machleidt, Jennifer Wilkinson, Olivier Hermine, Andrew L Kung, Adam J Stein, Damodharan Lakshminarasimhan, Michael T Hemann, Edward Scolnick, Yan-Ling Zhang, Jen Q Pan, Kimberly Stegmaier, Edward B Holson
Exploiting an Asp-Glu "switch" in glycogen synthase kinase 3 to design paralog-selective inhibitors for use in acute myeloid leukemia. Science translational medicine 10 (431) (2019)
Yana Pikman, Kimberly Stegmaier
Targeted therapy for fusion-driven high-risk acute leukemia. Blood 132 (12) (2018)