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John B Bruning

Scopus Author ID ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 43

Top Venues

ACS chemical biology

Biochemistry

Chemistry (Weinheim an der Bergstrasse, Germany)

Acta crystallographica. Section D, Structural biology

University of Adelaide

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Adelaide Aug 1o 2012

Australia

Senior Lecturer :: Molecular and Cellular Biology

Publications

Damian L Stachura, Stephanie Nguyen, Steven W Polyak, Blagojce Jovcevski, John B Bruning, Andrew D Abell
Structural Study of Potent Triazole-Based Inhibitors of Staphylococcus aureus Biotin Protein Ligase. ACS medicinal chemistry letters 14 (3) (2023)
Rebecca L Frkic, Jordan L Pederick, Aimee J Horsfall, Blagojce Jovcevski, Elise E Crame, Wioleta Kowalczyk, Tara Louise Pukala, Mi Ra Chang, Jie Zheng, Anne-Laure Blayo, Andrew D Abell, Theodore M Kamenecka, Joshua S Harbort, Jeffrey R Harmer, Patrick R Griffin, John B Bruning
PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles. ACS chemical biology 18 (5) (2023)
Jordan L Pederick, Jack Klose, Blagojce Jovcevski, Tara Louise Pukala, John B Bruning
Escherichia coli YgiC and YjfC Possess Peptide─Spermidine Ligase Activity. Biochemistry 62 (4) (2023)
Rebecca L Frkic, Jordan L Pederick, Aimee J Horsfall, Blagojce Jovcevski, Elise E Crame, Wioleta Kowalczyk, Tara Louise Pukala, Mi Ra Chang, Jie Zheng, Anne-Laure Blayo, Andrew D Abell, Theodore M Kamenecka, Joshua S Harbort, Jeffrey R Harmer, Patrick R Griffin, John B Bruning
PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles. ACS chemical biology 18 (5) (2023)
Bethiney C Vandborg, Aimee J Horsfall, Jordan L Pederick, Andrew D Abell, John B Bruning
Towards a High-Affinity Peptidomimetic Targeting Proliferating Cell Nuclear Antigen from Aspergillus fumigatus . Journal of fungi (Basel, Switzerland) 9 (11) (2023)
Aimee J Horsfall, Theresa Chav, Jordan L Pederick, Zoya Kikhtyak, Bethiney C Vandborg, Wioleta Kowalczyk, Denis B Scanlon, Wayne D Tilley, Theresa E Hickey, Andrew D Abell, John B Bruning
Designing Fluorescent Nuclear Permeable Peptidomimetics to Target Proliferating Cell Nuclear Antigen. Journal of medicinal chemistry (2023)
Daniel P McDougal, Harinda Rajapaksha, Jordan L Pederick, John B Bruning
warpDOCK: Large-Scale Virtual Drug Discovery Using Cloud Infrastructure. ACS omega 8 (32) (2023)
Rebecca L Frkic, Jordan L Pederick, Aimee J Horsfall, Blagojce Jovcevski, Elise E Crame, Wioleta Kowalczyk, Tara Louise Pukala, Mi Ra Chang, Jie Zheng, Anne-Laure Blayo, Andrew D Abell, Theodore M Kamenecka, Joshua S Harbort, Jeffrey R Harmer, Patrick R Griffin, John B Bruning
PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles. ACS chemical biology (2023)
Wanisa Salaemae, Andrew P Thompson, Birgit I Gaiser, Kwang Jun Lee, Michael T Huxley, Christopher J Sumby, Steven W Polyak, Andrew D Abell, John B Bruning, Kate L Wegener
Fortuitous In Vitro Compound Degradation Produces a Tractable Hit against Mycobacterium tuberculosis Dethiobiotin Synthetase: A Cautionary Tale of What Goes In Does Not Always Come Out. ACS chemical biology (2023)
Jordan L Pederick, Jack Klose, Blagojce Jovcevski, Tara Louise Pukala, John B Bruning
Escherichia coli YgiC and YjfC Possess Peptide─Spermidine Ligase Activity. Biochemistry (2023)
Rebecca L Frkic, Jordan L Pederick, Aimee J Horsfall, Blagojce Jovcevski, Elise E Crame, Wioleta Kowalczyk, Tara Louise Pukala, Mi Ra Chang, Jie Zheng, Anne-Laure Blayo, Andrew D Abell, Theodore M Kamenecka, Joshua S Harbort, Jeffrey R Harmer, Patrick R Griffin, John B Bruning
PPARγ Corepression Involves Alternate Ligand Conformation and Inflation of H12 Ensembles. ACS chemical biology 18 (5) (2023)
Jordan L Pederick, Jack Klose, Blagojce Jovcevski, Tara Louise Pukala, John B Bruning
Escherichia coli YgiC and YjfC Possess Peptide─Spermidine Ligase Activity. Biochemistry 62 (4) (2023)
Justin C Miller, Joel H Z Lee, Mark A Mclean, Rebecca R Chao, Isobella S J Stone, Tara Louise Pukala, John B Bruning, James J De Voss, Mary A Schuler, Stephen G Sligar, Stephen G Bell
Engineering C-C Bond Cleavage Activity into a P450 Monooxygenase Enzyme. Journal of the American Chemical Society (2023)
Jordan L Pederick, Jack Klose, Blagojce Jovcevski, Tara Louise Pukala, John B Bruning
Escherichia coli YgiC and YjfC Possess Peptide─Spermidine Ligase Activity. Biochemistry 62 (4) (2023)
Jordan L Pederick, Jessica C Woolman, John B Bruning
Comparative functional and structural analysis of Pseudomonas aeruginosa ᴅ-alanine-ᴅ-alanine ligase isoforms as prospective antibiotic targets. The FEBS journal (2023)
Matthew N Podgorski, Tom Coleman, Luke R Churchman, John B Bruning, James J De Voss, Stephen G Bell
Investigating the Active Oxidants Involved in Cytochrome P450 Catalyzed Sulfoxidation Reactions. Chemistry (Weinheim an der Bergstrasse, Germany) (2022)
Emily L Button, Joseph J Rossi, Daniel P McDougal, John B Bruning, Daniel J Peet, David C Bersten, Jill A Rosenfeld, Murray L Whitelaw
Characterization of functionally deficient SIM2 variants found in patients with neurological phenotypes. The Biochemical journal 479 (13) (2022)
Stephanie Nguyen, Blagojce Jovcevski, Jia Quyen Truong, Tara L Pukala, John B Bruning
A structural model of the human plasminogen and Aspergillus fumigatus enolase complex. Proteins 90 (8) (2022)
Stephanie Nguyen, Blagojce Jovcevski, Tara Louise Pukala, John B Bruning
Structural insights into the antifungal drug target guanosine monophosphate synthase from Aspergillus fumigatus. Acta crystallographica. Section D, Structural biology 78 (Pt 2) (2022)
Amna Ghith, Daniel Z Doherty, John B Bruning, Robert A Russell, James J De Voss, Stephen G Bell
The Structures of the Steroid Binding CYP142 Cytochrome P450 Enzymes from Mycobacterium ulcerans and Mycobacterium marinum . ACS infectious diseases 8 (8) (2022)
Tom Coleman, Daniel Z Doherty, Ting Zhang, Matthew N Podgorski, Ruihong Qiao, Joel H Z Lee, John B Bruning, James J De Voss, Weihong Zhou, Stephen G Bell
Exploring the Factors which Result in Cytochrome P450 Catalyzed Desaturation Versus Hydroxylation. Chemistry, an Asian journal (2022)
Tom Coleman, Joel H Z Lee, Alicia M Kirk, Daniel Z Doherty, Matthew N Podgorski, Dilshi K Pinidiya, John B Bruning, James J De Voss, Elizabeth H Krenske, Stephen G Bell
Enabling Aromatic Hydroxylation in a Cytochrome P450 Monooxygenase Enzyme through Protein Engineering. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (67) (2022)
Damian L Stachura, Stephanie Nguyen, Steven W Polyak, Blagojce Jovcevski, John B Bruning, Andrew D Abell
A New 1,2,3-Triazole Scaffold with Improved Potency against Staphylococcus aureus Biotin Protein Ligase. ACS infectious diseases (2022)
Jia Quyen Truong, Stephanie Nguyen, John B Bruning, Keith E Shearwin
Simplified heavy-atom derivatization of protein structures via co-crystallization with the MAD tetragon tetrabromoterephthalic acid. Acta crystallographica. Section F, Structural biology communications 77 (Pt 5) (2021)
Andrew C Marshall, John B Bruning
Engineering potassium activation into biosynthetic thiolase. The Biochemical journal 478 (15) (2021)
Charlotte E J Downes, Barbara J McClure, John B Bruning, Elyse C Page, James Breen, Jacqueline A Rehn, David T Yeung, Deborah L White
Acquired JAK2 mutations confer resistance to JAK inhibitors in cell models of acute lymphoblastic leukemia. NPJ precision oncology 5 (1) (2021)
Aimee J Horsfall, Daniel P McDougal, Denis B Scanlon, John B Bruning, Andrew D Abell
Approaches to Introduce Helical Structure in Cysteine-Containing Peptides with a Bimane Group. Chembiochem : a European journal of chemical biology 22 (17) (2021)
Nicholas C Schumann, Kwang Jun Lee, Andrew P Thompson, Wanisa Salaemae, Jordan L Pederick, Thomas Avery, Birgit I Gaiser, James Hodgkinson-Bean, Grant W Booker, Steven W Polyak, John B Bruning, Kate L Wegener, Andrew D Abell
Inhibition of Mycobacterium tuberculosis Dethiobiotin Synthase (MtDTBS): Toward Next-Generation Antituberculosis Agents. ACS chemical biology 16 (11) (2021)
Matthew N Podgorski, Tom Coleman, Peter D Giang, C Ruth Wang, John B Bruning, Paul V Bernhardt, James J De Voss, Stephen G Bell
To Be, or Not to Be, an Inhibitor: A Comparison of Azole Interactions with and Oxidation by a Cytochrome P450 Enzyme. Inorganic chemistry 61 (1) (2021)
Inna Slynko, Stephanie Nguyen, Eline M C Hamilton, Lisanne E Wisse, Iwan J P de Esch, Chris de Graaf, John B Bruning, Christopher G Proud, Truus E M Abbink, Marjo S van der Knaap
Vanishing white matter: Eukaryotic initiation factor 2B model and the impact of missense mutations. Molecular genetics & genomic medicine 9 (3) (2021)
Jordan L Pederick, Andrew P Thompson, Stephen G Bell, John B Bruning
d-Alanine-d-alanine ligase as a model for the activation of ATP-grasp enzymes by monovalent cations. The Journal of biological chemistry 295 (23) (2020)
Matthew N Podgorski, Joshua S Harbort, Tom Coleman, Jeanette E Stok, Jake A Yorke, Luet-Lok Wong, John B Bruning, Paul V Bernhardt, James J De Voss, Jeffrey R Harmer, Stephen G Bell
Biophysical Techniques for Distinguishing Ligand Binding Modes in Cytochrome P450 Monooxygenases. Biochemistry 59 (9) (2020)
Stephanie Nguyen, Blagojce Jovcevski, Tara Louise Pukala, John B Bruning
Nucleoside selectivity of Aspergillus fumigatus nucleoside-diphosphate kinase. The FEBS journal 288 (7) (2020)
Tom Coleman, Jeanette E Stok, Matthew N Podgorski, John B Bruning, James J De Voss, Stephen G Bell
Structural insights into the role of the acid-alcohol pair of residues required for dioxygen activation in cytochrome P450 enzymes. Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 25 (4) (2020)
Kwang Jun Lee, William Tieu, Beatriz Blanco-Rodriguez, Ashleigh S Paparella, Jingxian Yu, Andrew J Hayes, Jiage Feng, Andrew C Marshall, Benjamin Noll, Robert Milne, Danielle Cini, Matthew C J Wilce, Grant W Booker, John B Bruning, Steven W Polyak, Andrew D Abell
Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads. ACS chemical biology 14 (9) (2019)
Yong Jia, Crista A Burbidge, Crystal Sweetman, Emi Schutz, Kathleen L Soole, Colin L D Jenkins, Robert E W Hancock, John B Bruning, Christopher M Ford
An aldo-keto reductase with 2-keto-l-gulonate reductase activity functions in l-tartaric acid biosynthesis from vitamin C in Vitis vinifera. The Journal of biological chemistry 294 (44) (2019)
Jia Quyen Truong, Santosh Panjikar, Linda Shearwin-Whyatt, John B Bruning, Keith E Shearwin
Combining random microseed matrix screening and the magic triangle for the efficient structure solution of a potential lysin from bacteriophage P68. Acta crystallographica. Section D, Structural biology 75 (Pt 7) (2019)
Mi Ra Chang, Anthony Ciesla, Timothy S Strutzenberg, Scott J Novick, Yuanjun He, Ruben D Garcia-Ordonez, Rebecca L Frkic, John B Bruning, Theodore M Kamenecka, Patrick R Griffin
Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways. ACS chemical biology 14 (5) (2019)
Aimee J Horsfall, Andrew D Abell, John B Bruning
Targeting PCNA with Peptide Mimetics for Therapeutic Purposes. Chembiochem : a European journal of chemical biology 21 (4) (2019)
Kate L Wegener, Amy E McGrath, Nicholas E Dixon, Aaron J Oakley, Denis B Scanlon, Andrew D Abell, John B Bruning
Rational Design of a 310 -Helical PIP-Box Mimetic Targeting PCNA, the Human Sliding Clamp. Chemistry (Weinheim an der Bergstrasse, Germany) 24 (44) (2018)
Andrew P Thompson, Kate L Wegener, Grant W Booker, Steven W Polyak, John B Bruning
Precipitant-ligand exchange technique reveals the ADP binding mode in Mycobacterium tuberculosis dethiobiotin synthetase. Acta crystallographica. Section D, Structural biology 74 (Pt 10) (2018)
Andrew C Marshall, Alice J Kroker, Lauren A M Murray, Kahlia Gronthos, Harinda Rajapaksha, Kate L Wegener, John B Bruning
Structure of the sliding clamp from the fungal pathogen Aspergillus fumigatus (AfumPCNA) and interactions with Human p21. The FEBS journal 284 (6) (2017)
Rebecca L Frkic, Yuanjun He, Beatriz B Rodriguez, Mi Ra Chang, Dana Kuruvilla, Anthony Ciesla, Andrew D Abell, Theodore M Kamenecka, Patrick R Griffin, John B Bruning
Structure-Activity Relationship of 2,4-Dichloro-N-(3,5-dichloro-4-(quinolin-3-yloxy)phenyl)benzenesulfonamide (INT131) Analogs for PPARγ-Targeted Antidiabetics. Journal of medicinal chemistry 60 (11) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

John B Bruning