John Dudley Isaacs (John Isaacs, John D Isaacs)

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 37

Top Topics

Rheumatoid Arthritis

Disease Activity

Interstitial Lung Disease

Top Venues

Annals of the rheumatic diseases

Nature communications

Pharmaceutical statistics

Nature reviews. Rheumatology

This page only lists publications with an associated author ORCID identifier.

Publications

Kenneth F Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel Ronald Schulz, Henrik E Mei, Lucy MacDonald, Arthur G Pratt, Andrew Filby, Amy E Anderson, John Dudley Isaacs
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature communications 15 (1) (2024)
Kevin L Winthrop, Philip Mease, Andreas Kerschbaumer, Reinhard E Voll, Ferdinand C Breedveld, Josef S Smolen, Jacques-Eric Gottenberg, Xenofon Baraliakos, Hans P Kiener, Daniel Aletaha, John Dudley Isaacs, Maya H Buch, Mary K Crow, Jonathan Kay, Leslie J Crofford, Ronald F Van Vollenhoven, Caroline Ospelt, Stefan Siebert, Margreet Kloppenburg, Iain B McInnes, Thomas Wj Huizinga, Ellen M Gravallese
Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2023. Annals of the rheumatic diseases 83 (4) (2024)
Kenneth F Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel Ronald Schulz, Henrik E Mei, Lucy MacDonald, Arthur G Pratt, Andrew Filby, Amy E Anderson, John Dudley Isaacs
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature communications 15 (1) (2024)
Kevin L Winthrop, Philip Mease, Andreas Kerschbaumer, Reinhard E Voll, Ferdinand C Breedveld, Josef S Smolen, Jacques-Eric Gottenberg, Xenofon Baraliakos, Hans P Kiener, Daniel Aletaha, John Dudley Isaacs, Maya H Buch, Mary K Crow, Jonathan Kay, Leslie J Crofford, Ronald F Van Vollenhoven, Caroline Ospelt, Stefan Siebert, Margreet Kloppenburg, Iain B McInnes, Thomas Wj Huizinga, Ellen M Gravallese
Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2023. Annals of the rheumatic diseases 83 (4) (2024)
Kenneth F Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel Ronald Schulz, Henrik E Mei, Lucy MacDonald, Arthur G Pratt, Andrew Filby, Amy E Anderson, John Dudley Isaacs
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature communications 15 (1) (2024)
Kenneth F Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel Ronald Schulz, Henrik E Mei, Lucy MacDonald, Arthur G Pratt, Andrew Filby, Amy E Anderson, John Dudley Isaacs
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature communications 15 (1) (2024)
John Dudley Isaacs
CAR T Cells - A New Horizon for Autoimmunity? The New England journal of medicine 390 (8) (2024)
Kenneth F Baker, David McDonald, Gillian Hulme, Rafiqul Hussain, Jonathan Coxhead, David Swan, Axel Ronald Schulz, Henrik E Mei, Lucy MacDonald, Arthur G Pratt, Andrew Filby, Amy E Anderson, John Dudley Isaacs
Single-cell insights into immune dysregulation in rheumatoid arthritis flare versus drug-free remission. Nature communications 15 (1) (2024)
John Dudley Isaacs
CAR T Cells - A New Horizon for Autoimmunity? The New England journal of medicine 390 (8) (2024)
Philippa D K Curry, Gabriela Arredondo Hector Chinoy, Meghna Jani, Darren Plant, Kimmie L Hyrich, Ann W Morgan, Anthony G Wilson, John Dudley Isaacs, Andrew P Morris, Richard B Warren, James Bluett
The Effect of COVID-19 on Medication Adherence in a Rheumatoid Arthritis (BRAGGSS) and Psoriatic Arthritis (OUTPASS) UK Cohort. The Journal of rheumatology (2023)
Joshua L Bennett, Arthur G Pratt, Richard Dodds, Avan A Sayer, John Dudley Isaacs
Rheumatoid sarcopenia: loss of skeletal muscle strength and mass in rheumatoid arthritis. Nature reviews. Rheumatology (2023)
Kevin L Winthrop, John Dudley Isaacs, Phillip J Mease, Dimitrios T Boumpas, Xenofon Baraliakos, Jacques-Eric Gottenberg, Stefan Siebert, Marta Mosca, Neil Basu, Dana Orange, R Lories, Daniel Aletaha, Iain B McInnes, Thomas Wj Huizinga, Reinhard E Voll, Ellen M Gravallese, Ferry C Breedveld, Josef S Smolen
Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2022. Annals of the rheumatic diseases (2023)
Christina Yap, Olga Solovyeva, Johann S de Bono, Jan Rekowski, Dhrusti Patel, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Richard Wilson Peck, Kathryn S Hayward, Sally Hopewell, Moreno Ursino, Khadija Rerhou Rantell, Melanie Jane Calvert, Shing Lee, Andrew Kightley, Deborah Ashby, An-Wen Chan, Elizabeth Garrett-Mayer, John Dudley Isaacs, Robert Golub, Olga Kholmanskikh, Dawn P Richards, Oliver Boix, James Matcham, Lesley Seymour, Susan Percy Ivy, Lynley V Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan D Berlin, Aude Espinasse, Munyaradzi Dimairo, Christopher J Weir
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ (Clinical research ed.) 383 (2023)
Kevin L Winthrop, John Dudley Isaacs, Phillip J Mease, Dimitrios T Boumpas, Xenofon Baraliakos, Jacques-Eric Gottenberg, Stefan Siebert, Marta Mosca, Neil Basu, Dana Orange, R Lories, Daniel Aletaha, Iain B McInnes, Thomas Wj Huizinga, Reinhard E Voll, Ellen M Gravallese, Ferry C Breedveld, Josef S Smolen
Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2022. Annals of the rheumatic diseases (2023)
Christina Yap, Jan Rekowski, Moreno Ursino, Olga Solovyeva, Dhrusti Patel, Munyaradzi Dimairo, Christopher J Weir, An-Wen Chan, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Richard Wilson Peck, Kathryn S Hayward, Melanie Jane Calvert, Khadija Rerhou Rantell, Shing Lee, Andrew Kightley, Sally Hopewell, Deborah Ashby, Elizabeth Garrett-Mayer, John Dudley Isaacs, Robert Golub, Olga Kholmanskikh, Dawn P Richards, Oliver Boix, James Matcham, Lesley Seymour, Susan Percy Ivy, Lynley V Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan D Berlin, Aude Espinasse, Johann S de Bono
Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ (Clinical research ed.) 383 (2023)
Chuan Fu Yap, Nisha Nair, Annick de Vries, Floris C Loeff, Ann W Morgan, John Dudley Isaacs, Anthony G Wilson, Kimme L Hyrich, Richard B Warren, Darren Plant
HLA-DRB1 and HLA-DQA1 associated with immunogenicity to adalimumab therapy in patients with rheumatoid arthritis. Annals of the rheumatic diseases (2023)
Ciara M O'Brien, George D Kitas, Fiona Rayner, John Dudley Isaacs, Kenneth F Baker, Arthur G Pratt, Christopher Dominic Buckley, Karim Raza, Andrew Filer, Stefan Siebert, Iain B McInnes, Andrew McGucken, Sally A M Fenton, null null
Number of days required to measure sedentary time and physical activity using accelerometery in rheumatoid arthritis: a reliability study. Rheumatology international (2023)
Samantha Louise Smith, Sheree Alexander, Nisha Nair, Sebastien Viatte, Stephen Eyre, Kimmie L Hyrich, Ann W Morgan, Anthony G Wilson, John Dudley Isaacs, Darren Plant, Richard B Warren
Pre-treatment calprotectin (MRP8/14) provides no added value to testing CRP alone in terms of predicting response to TNF inhibitors in rheumatoid arthritis in a post hoc analysis. Annals of the rheumatic diseases (2023)
Samantha Louise Smith, Sheree Alexander, Nisha Nair, Sebastien Viatte, Stephen Eyre, Kimmie L Hyrich, Ann W Morgan, Anthony G Wilson, John Dudley Isaacs, Darren Plant, Richard B Warren
Pre-treatment calprotectin (MRP8/14) provides no added value to testing CRP alone in terms of predicting response to TNF inhibitors in rheumatoid arthritis in a post hoc analysis. Annals of the rheumatic diseases (2023)
Kevin L Winthrop, John Dudley Isaacs, Phillip J Mease, Dimitrios T Boumpas, Xenofon Baraliakos, Jacques-Eric Gottenberg, Stefan Siebert, Marta Mosca, Neil Basu, Dana Orange, R Lories, Daniel Aletaha, Iain B McInnes, Thomas Wj Huizinga, Reinhard E Voll, Ellen M Gravallese, Ferry C Breedveld, Josef S Smolen
Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2022. Annals of the rheumatic diseases (2023)
Kevin L Winthrop, Philip Mease, Andreas Kerschbaumer, Reinhard E Voll, Ferdinand C Breedveld, Josef S Smolen, Jacques-Eric Gottenberg, Xenofon Baraliakos, Hans P Kiener, Daniel Aletaha, John Dudley Isaacs, Maya H Buch, Mary K Crow, Jonathan Kay, Leslie J Crofford, Ronald F Van Vollenhoven, Caroline Ospelt, Stefan Siebert, Margreet Kloppenburg, Iain B McInnes, Thomas Wj Huizinga, Ellen M Gravallese
Unmet need in rheumatology: reports from the Advances in Targeted Therapies meeting, 2023. Annals of the rheumatic diseases (2023)
Daniel Aletaha, Andreas Kerschbaumer, Kastriot Kastrati, Christian Dejaco, Maxime Dougados, Iain B McInnes, Naveed Sattar, Tanja Alexandra Stamm, Tsutomu Takeuchi, Michael Trauner, Désirée Mfm van der Heijde, Marieke Voshaar, Kevin L Winthrop, Angelo Ravelli, Neil Betteridge, Gerd-Rüdiger R Burmester, Johannes W J Bijlsma, Vivian Bykerk, Roberto Caporali, Ernest H S Choy, Catalin Codreanu, Bernard Combe, Mary K Crow, Maarten P T de Wit, Paul Emery, Roy M Fleischmann, Cem Gabay, Merete Lund Hetland, Kimmie L Hyrich, AnnaMaria Iagnocco, John Dudley Isaacs, Joel M Kremer, Xavier Mariette, Peter A Merkel, Eduardo F Mysler, Peter Nash, Michael T Nurmohamed, Karel Pavelka, Gyula Poor, Andrea Rubbert-Roth, Hendrik Schulze-Koops, Anja Strangfeld, Yoshiya Tanaka, Josef S Smolen
Consensus statement on blocking interleukin-6 receptor and interleukin-6 in inflammatory conditions: an update. Annals of the rheumatic diseases (2022)
Faye A H Cooles, Jessica R Tarn, Dennis William Lendrem, Najib Naamane, Chung Ma Lin, Ben Millar, Nicola J Maney, Amy E Anderson, Nishanthi Thalayasingam, Julie Diboll, Vincent Bondet, Darragh Duffy, Michael R Barnes, Graham R Smith, Sandra Ng, David Watson, Rafael Henkin, Andrew P Cope, Louise N Reynard, Arthur G Pratt, null null, John Dudley Isaacs
Interferon-α-mediated therapeutic resistance in early rheumatoid arthritis implicates epigenetic reprogramming. Annals of the rheumatic diseases (2022)
Gemma Vidal-Pedrola, Najib Naamane, James A Cameron, Arthur G Pratt, Andrew L Mellor, John Dudley Isaacs, Dagmar Scheel-Toellner, Amy E Anderson
Characterization of age-associated B cells in early drug-naïve rheumatoid arthritis patients. Immunology (2022)
Charlotte Lm Krieckaert, Astrid van Tubergen, Johanna Elin Gehin, Borja Hernández-Breijo, Guillaume Le Mélédo, Alejandro Balsa, Peter Böhm, Sasa Cucnik, Ori Elkayam, Guro L Goll, Femke Hooijberg, Meghna Jani, Patrick Dw Kiely, Neil McCarthy, Denis Mulleman, Victoria Navarro-Compán, Katherine Payne, Martin E Perry, Chamaida Plasencia-Rodriguez, Simon R Stones, Silje Watterdal Syversen, Annick de Vries, Katherine M Ward, Gertjan Wolbink, John Dudley Isaacs
EULAR points to consider for therapeutic drug monitoring of biopharmaceuticals in inflammatory rheumatic and musculoskeletal diseases. Annals of the rheumatic diseases (2022)
Robert B M Landewe, Féline P B Kroon, Alessia Alunno, Aurélie Najm, Johannes W J Bijlsma, Gerd-Rüdiger R Burmester, Roberto Caporali, Bernard Combe, Richard P Conway, Jeffrey R Curtis, Ori Elkayam, Laure Gossec, Marloes W Heijstek, Lukas Haupt, AnnaMaria Iagnocco, John Dudley Isaacs, István Ábel Juhász, Suzi Makri, Xavier Mariette, Iain B McInnes, Puja Mehta, Ulf Mueller-Ladner, Hendrik Schulze-Koops, Josef S Smolen, Dieter Wiek, Kevin L Winthrop, Victoria Navarro-Compán, Pedro M Machado
EULAR recommendations for the management and vaccination of people with rheumatic and musculoskeletal diseases in the context of SARS-CoV-2: the November 2021 update. Annals of the rheumatic diseases 81 (12) (2022)
Chung M A Lin, Faye A H Cooles, John Dudley Isaacs
Precision medicine: the precision gap in rheumatic disease. Nature reviews. Rheumatology 18 (12) (2022)
Alessia Alunno, Aurélie Najm, Pedro M Machado, Heidi Bertheussen, Gerd-Rüdiger R Burmester, Francesco Carubbi, Gabriele De Marco, Roberto Giacomelli, Olivier Hermine, John Dudley Isaacs, Isabelle Kone-Paut, César Magro-Checa, Iain B McInnes, Pier Luigi Meroni, Luca Quartuccio, A V Ramanan, Manuel Ramos-Casals, Javier Rodríguez Carrio, Hendrik Schulze-Koops, Tanja Alexandra Stamm, Sander W Tas, Benjamin Terrier, Dennis G McGonagle, Xavier Mariette
2021 update of the EULAR points to consider on the use of immunomodulatory therapies in COVID-19. Annals of the rheumatic diseases (2021)
Alessia Alunno, Aurélie Najm, Pedro M Machado, Heidi Bertheussen, Gerd R Burmester, Francesco Carubbi, Gabriele De Marco, Roberto Giacomelli, Olivier Hermine, John Dudley Isaacs, Isabelle Kone-Paut, César Magro-Checa, Iain McInnes, Pier Luigi Meroni, Luca Quartuccio, Athimalaipet V Ramanan, Manuel Ramos-Casals, Javier Rodríguez Carrio, Hendrik Schulze-Koops, Tanja Alexandra Stamm, Sander W Tas, Benjamin Terrier, Dennis G McGonagle, Xavier Mariette
EULAR points to consider on pathophysiology and use of immunomodulatory therapies in COVID-19. Annals of the rheumatic diseases (2021)
Edith Serrano-Blesa, Andrew Porter, Dennis W Lendrem, Costantino Pitzalis, Anne Barton, Achim Treumann, John Dudley Isaacs
Robust optimization of SWATH-MS workflow for human blood serum proteome analysis using a quality by design approach. Clinical proteomics 18 (1) (2021)
Syed Sa Gilani, Nisha Nair, Darren Plant, Kimmie L Hyrich, Ann W Morgan, Andrew P Morris, Anthony G Wilson, John Dudley Isaacs, Richard B Warren, James Bluett, null null
Pharmacogenetics of TNF inhibitor response in rheumatoid arthritis utilizing the two-component disease activity score. Pharmacogenomics 21 (16) (2020)
John Dudley Isaacs, Gerd-Rüdiger R Burmester
Smart battles: immunosuppression versus immunomodulation in the inflammatory RMDs. Annals of the rheumatic diseases 79 (8) (2020)
Jessica R Tarn, Dennis William Lendrem, John Dudley Isaacs
In search of pathobiological endotypes: a systems approach to early rheumatoid arthritis. Expert review of clinical immunology 16 (6) (2020)
Robert B M Landewe, Pedro M Machado, Féline P B Kroon, Hans Wj Bijlsma, Gerd R Burmester, Loreto Carmona, Bernard Combe, Massimo Galli, Laure Gossec, Annamaria Iagnocco, John Dudley Isaacs, Xavier Mariette, Iain McInnes, Ulf Mueller-Ladner, Peter Openshaw, Josef S Smolen, Tanja Alexandra Stamm, Dieter Wiek, Hendrik Schulze-Koops
EULAR provisional recommendations for the management of rheumatic and musculoskeletal diseases in the context of SARS-CoV-2. Annals of the rheumatic diseases 79 (7) (2020)
Kenneth F Baker, John Dudley Isaacs, Ben Thompson
"Living a normal life": a qualitative study of patients' views of medication withdrawal in rheumatoid arthritis. BMC rheumatology 3 (2019)
Harold Fellermann, Ben Shirt-Ediss, Jerzy Kozyra, Matt Linsley, Dennis William Lendrem, John Dudley Isaacs, Thomas P Howard
Design of experiments and the virtual PCR simulator: An online game for pharmaceutical scientists and biotechnologists. Pharmaceutical statistics 18 (4) (2019)
Beverley Clare Lendrem, Dennis William Lendrem, Arthur G Pratt, Najib Naamane, Peter McMeekin, Wan-Fai Ng, A Joy Allen, H Michael Power, John Dudley Isaacs
Between a ROC and a hard place: Teaching prevalence plots to understand real world biomarker performance in the clinic. Pharmaceutical statistics 18 (6) (2019)