Johann S de Bono (Maha Hussain, Johann De Bonno, Johann de Bono, J de Bono)

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 46

Top Topics

Prostate Cancer

Intellectual Disability

Radical Prostatectomy

Top Venues

Clinical cancer research : an official journal of the American Association for Cancer Research

Cancer reports (Hoboken, N.J.)

Cancer research

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

This page only lists publications with an associated author ORCID identifier.

Publications

Christina Yap, Olga Solovyeva, Johann S de Bono, Jan Rekowski, Dhrusti Patel, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Richard Wilson Peck, Kathryn S Hayward, Sally Hopewell, Moreno Ursino, Khadija Rerhou Rantell, Melanie Jane Calvert, Shing Lee, Andrew Kightley, Deborah Ashby, An-Wen Chan, Elizabeth Garrett-Mayer, John Dudley Isaacs, Robert Golub, Olga Kholmanskikh, Dawn P Richards, Oliver Boix, James Matcham, Lesley Seymour, Susan Percy Ivy, Lynley V Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan D Berlin, Aude Espinasse, Munyaradzi Dimairo, Christopher J Weir
Enhancing reporting quality and impact of early phase dose-finding clinical trials: CONSORT Dose-finding Extension (CONSORT-DEFINE) guidance. BMJ (Clinical research ed.) 383 (2023)
Joaquin Mateo, Johann S de Bono, Karim Fizazi, Fred Saad, Neal D Shore, Shahneen Sandhu, Kim N Chi, Archana M Agarwal, David Olmos, Antoine Thiery-Vuillemin, Mustafa Özgüroğlu, Niven Mehra, Nobuaki Matsubara, Jae Young Joung, Charles Padua, Ernesto Korbenfeld, Jinyu Kang, Helen Marshall, Zhongwu Lai, Alan Barnicle, Christian Poehlein, Natalia Lukashchuk, Maha H A Hussain
Olaparib for the Treatment of Patients With Metastatic Castration-Resistant Prostate Cancer and Alterations in BRCA1 and/or BRCA2 in the PROfound Trial. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Christina Yap, Jan Rekowski, Moreno Ursino, Olga Solovyeva, Dhrusti Patel, Munyaradzi Dimairo, Christopher J Weir, An-Wen Chan, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Richard Wilson Peck, Kathryn S Hayward, Melanie Jane Calvert, Khadija Rerhou Rantell, Shing Lee, Andrew Kightley, Sally Hopewell, Deborah Ashby, Elizabeth Garrett-Mayer, John Dudley Isaacs, Robert Golub, Olga Kholmanskikh, Dawn P Richards, Oliver Boix, James Matcham, Lesley Seymour, Susan Percy Ivy, Lynley V Marshall, Antoine Hommais, Rong Liu, Yoshiya Tanaka, Jordan D Berlin, Aude Espinasse, Johann S de Bono
Enhancing quality and impact of early phase dose-finding clinical trial protocols: SPIRIT Dose-finding Extension (SPIRIT-DEFINE) guidance. BMJ (Clinical research ed.) 383 (2023)
Olga Solovyeva, Munyaradzi Dimairo, Christopher J Weir, Siew Wan Hee, Aude Espinasse, Moreno Ursino, Dhrusti Patel, Andrew Kightley, Sarah Hughes, Thomas F Jaki, Adrian P Mander, Thomas R Jeffry Evans, Shing Lee, Sally Hopewell, Khadija Rerhou Rantell, An-Wen Chan, Alun Bedding, Richard Stephens, Dawn P Richards, Lesley Roberts, John Kirkpatrick, Johann S de Bono, Christina Yap
Development of consensus-driven SPIRIT and CONSORT extensions for early phase dose-finding trials: the DEFINE study. BMC medicine 21 (1) (2023)
Susan Halabi, Qian Yang, Akash Roy, Bin Luo, John C Araujo, Christopher Logothetis, Cora N Sternberg, Andrew J Armstrong, Michael A Carducci, Kim N Chi, Johann S de Bono, Daniel P Petrylak, Karim Fizazi, Celestia S Higano, Michael J Morris, Dana E Rathkopf, Fred Saad, Charles J Ryan, Eric J Small, William Kevin Kelly
External Validation of a Prognostic Model of Overall Survival in Men With Chemotherapy-Naïve Metastatic Castration-Resistant Prostate Cancer. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Christina Guo, Adam Sharp, Bora Gurel, Mateus Crespo, Ines Figueiredo, Suneil Jain, Ursula Vogl, Jan Rekowski, Mahtab Rouhifard, Lewis Gallagher, Wei Yuan, Suzanne Carreira, Khobe Chandran, Alec Paschalis, Ilaria Colombo, Anastasios Stathis, Claudia Bertan, George Seed, Jane Goodall, Florence I Raynaud, Ruth Ruddle, Karen E Swales, Jason Malia, Denisa Bogdan, Crescens Tiu, Reece Caldwell, Caterina Aversa, Ana Ferreira, Antje Neeb, Nina Tunariu, Daniel Westaby, Juliet Carmichael, Maria de Los Dolores Fenor de la Maza, Christina Yap, Ruth Matthews, Hannah Badham, Toby Prout, Alison Turner, Mona Parmar, Holly Tovey, Ruth Riisnaes, Penny Flohr, Jesús Gil, David Waugh, Shaun Decordova, Anna Schlag, Bianca Calì, Andrea Alimonti, Johann S de Bono
Targeting myeloid chemotaxis to reverse prostate cancer therapy resistance. Nature (2023)
Daniela Brina, Adele Ponzoni, Martina Troiani, Bianca Calì, Emiliano Pasquini, Giuseppe Attanasio, Simone Mosole, Michela Mirenda, Mariantonietta D'Ambrosio, Manuel Colucci, Ilaria Guccini, Ajinkya Revandkar, Abdullah Alajati, Toma Tebaldi, Deborah Donzel, Fabio Lauria, Nahjme Parhizgari, Aurora Valdata, Martino Maddalena, Arianna Calcinotto, Marco Bolis, Andrea Rinaldi, Simon T Barry, Jan Hendrik Rüschoff, Marianna Sabbadin, Semini Sumanasuriya, Mateus Crespo, Adam Sharp, Wei Yuan, Mathew Grinu, Alexandra Boyle, Cynthia Miller, Lloyd C Trotman, Nicolas Delaleu, Matteo Fassan, Holger Moch, Gabriella Viero, Johann S de Bono, Andrea Alimonti
The Akt/mTOR and MNK/eIF4E pathways rewire the prostate cancer translatome to secrete HGF, SPP1 and BGN and recruit suppressive myeloid cells. Nature cancer (2023)
Ravi A Madan, Fatima Karzai, David J VanderWeele, Heather H Cheng, Johann S de Bono
Poly(ADP-ribose) Polymerase Inhibitor Combinations in First-Line Metastatic Castration-Resistant Prostate Cancer: Increasing Toxicity With Unclear Benefits. Journal of clinical oncology : official journal of the American Society of Clinical Oncology (2023)
Marta J Llorca-Cardenosa, Lauren I Aronson, Dragomir B Krastev, Jadwiga Nieminuszczy, John Alexander, Feifei Song, Malgorzata Dylewska, Ronan Broderick, Rachel Brough, Astrid Zimmermann, Frank T Zenke, Bora Gurel, Ruth Riisnaes, Ana Ferreira, Theodoros I Roumeliotis, Jyoti Sharma Choudhary, Stephen J Pettitt, Johann S de Bono, Andres Cervantes, Syed Haider, Wojciech Niedzwiedz, Christopher J Lord, Irene Y Chong
SMG8/SMG9 Heterodimer Loss Modulates SMG1 Kinase to Drive ATR Inhibitor Resistance. Cancer research 82 (21) (2022)
Nicholas D James, Noel W Clarke, Adrian D Cook, Adnan Ali, Alex P Hoyle, Gerhardt Attard, Christopher D Brawley, Simon Chowdhury, William R Cross, David P Dearnaley, Johann S de Bono, Carlos Diaz-Montana, Duncan C Gilbert, Silke Gillessen Sommer, Clare Gilson, Robert J Jones, Ruth E Langley, Zafar I Malik, David J Matheson, Robin Millman, Chris C Parker, Cheryl Pugh, Hannah L Rush, J Martin Russell, Dominik R Berthold, Michelle L Buckner, Malcolm D Mason, Alastair W S Ritchie, Alison J Birtle, Susannah J Brock, Prantik Das, Dan Ford, Joanna Gale, Warren Grant, Emma K Gray, Peter J Hoskin, Mohammad M Khan, Caroline Manetta, Neil J McPhail, Joe M O'Sullivan, Omi Parikh, Carla Perna, Carmel J Pezaro, Andrew S Protheroe, Angus J Robinson, Sarah M Rudman, Denise J Sheehan, Narayanan N Srihari, Isabel Syndikus, Jacob S Tanguay, Carys W Thomas, Salil Vengalil, John Wagstaff, James P Wylie, Mahesh K B Parmar, Matthew R Sydes, null null
Abiraterone acetate plus prednisolone for metastatic patients starting hormone therapy: 5-year follow-up results from the STAMPEDE randomised trial (NCT00268476). International journal of cancer 151 (3) (2022)
Elizabeth A Coker, Adam Stewart, Bugra Ozer, Anna Minchom, Lisa Pickard, Ruth Ruddle, Suzanne Carreira, Sanjay Popat, Mary Er O'Brien, Florence Raynaud, Johann S de Bono, Bissan Al-Lazikani, Udai Banerji
Individualized Prediction of Drug Response and Rational Combination Therapy in NSCLC Using Artificial Intelligence-Enabled Studies of Acute Phosphoproteomic Changes. Molecular cancer therapeutics 21 (6) (2022)
Johann S de Bono, Jeffrey R Harris, Saskia M Burm, Adriaan Vanderstichele, Mischa A Houtkamp, Saida Aarass, Ruth Riisnaes, Ines Figueiredo, Daniel Nava Rodrigues, Rossitza Christova, Siel Olbrecht, Hans W M Niessen, Sigrid R Ruuls, Danita H Schuurhuis, Jeroen J Lammerts van Bueren, Esther C W Breij, Ignace Vergote
Systematic study of tissue factor expression in solid tumors. Cancer reports (Hoboken, N.J.) 6 (2) (2022)
Susana Banerjee, Vasiliki Michalarea, Joo Ern Ang, Alvaro H Ingles Garces, Andrea Biondo, Ionut-Gabriel Funingana, Martin Little, Ruth Ruddle, Florence I Raynaud, Ruth Riisnaes, Bora Gurel, Sue Chua, Nina Tunariu, Joanna C Porter, Toby Prout, Mona Parmar, Anna Zachariou, Alison Turner, Ben Jenkins, Stuart McIntosh, Ed Ainscow, Anna Minchom, Juanita Lopez, Johann S de Bono, Robert Jones, Emma C Hall, Natalie Cook, Bristi Basu, Udai Banerji
A Phase I Trial of CT900, a Novel α-Folate Receptor-Mediated Thymidylate Synthase Inhibitor, in Patients with Solid Tumors with Expansion Cohorts in Patients with High-Grade Serous Ovarian Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (21) (2022)
Beshara Sheehan, Antje J Neeb, Lorenzo Buroni, Alec Paschalis, Ruth Riisnaes, Bora Gurel, Veronica S Gil, Susana Miranda, Mateus Crespo, Christina Guo, Juan Jiménez Vacas, Ines Figueiredo, Ana Ferreira, Jon Welti, Wei Yuan, Suzanne Carreira, Adam Sharp, Johann S de Bono
Prostate-Specific Membrane Antigen Expression and Response to DNA Damaging Agents in Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (14) (2022)
Johann S de Bono, Jeffrey R Harris, Saskia M Burm, Adriaan Vanderstichele, Mischa A Houtkamp, Saida Aarass, Ruth Riisnaes, Ines Figueiredo, Daniel Nava Rodrigues, Rossitza Christova, Siel Olbrecht, Hans W M Niessen, Sigrid R Ruuls, Danita H Schuurhuis, Jeroen J Lammerts van Bueren, Esther C W Breij, Ignace Vergote
Systematic study of tissue factor expression in solid tumors. Cancer reports (Hoboken, N.J.) 6 (2) (2022)
Jimmy L Zhao, Karim Fizazi, Fred Saad, Kim N Chi, Mary-Ellen Taplin, Cora N Sternberg, Andrew J Armstrong, Johann S de Bono, William T Duggan, Howard I Scher
The Effect of Corticosteroids on Prostate Cancer Outcome Following Treatment with Enzalutamide: A Multivariate Analysis of the Phase III AFFIRM Trial. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (5) (2022)
Kim N Chi, Alan Barnicle, Caroline Sibilla, Zhongwu Lai, Claire Corcoran, J Carl Barrett, Carrie A Adelman, Ping Qiu, Ashley D Easter, Simon Dearden, Geoffrey R Oxnard, Archana M Agarwal, Arun A Azad, Johann S de Bono, Joaquin Mateo, David Olmos, Antoine Thiery-Vuillemin, Elizabeth A Harrington
Detection of BRCA1, BRCA2, and ATM Alterations in Matched Tumor Tissue and Circulating Tumor DNA in Patients with Prostate Cancer Screened in PROfound. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Niven Mehra, Karim Fizazi, Johann S de Bono, Philippe Barthélémy, Tanya Barauskas Dorff, Adam Stirling, Jean-Pascal Machiels, Davide Bimbatti, Deepak Kilari, Herlinde Dumez, Consuelo Buttigliero, Inge M van Oort, Elena Castro, Hsiang-Chun Chen, Nicola Di Santo, Liza DeAnnuntis, Cynthia G Healy, Giorgio Vittorio Scagliotti
Talazoparib, a Poly(ADP-ribose) Polymerase Inhibitor, for Metastatic Castration-resistant Prostate Cancer and DNA Damage Response Alterations: TALAPRO-1 Safety Analyses. The oncologist 27 (10) (2022)
Adam G Sowalsky, Ines Figueiredo, Rosina T Lis, Ilsa Coleman, Bora Gurel, Denisa Bogdan, Wei Yuan, Joshua W Russo, John R Bright, Nichelle C Whitlock, Shana Y Trostel, Anson T Ku, Radhika A Patel, Lawrence D True, Jonathan Welti, Juan M Jimenez-Vacas, Daniel Nava Rodrigues, Ruth Riisnaes, Antje J Neeb, Cynthia T Sprenger, Amanda Swain, Scott Wilkinson, Fatima Karzai, William L Dahut, Steven P Balk, Eva Corey, Peter S Nelson, Michael C Haffner, Stephen R Plymate, Johann S de Bono, Adam Sharp
Assessment of Androgen Receptor Splice Variant-7 as a Biomarker of Clinical Response in Castration-Sensitive Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (16) (2022)
Johann S de Bono, Jeffrey R Harris, Saskia M Burm, Adriaan Vanderstichele, Mischa A Houtkamp, Saida Aarass, Ruth Riisnaes, Ines Figueiredo, Daniel Nava Rodrigues, Rossitza Christova, Siel Olbrecht, Hans W M Niessen, Sigrid R Ruuls, Danita H Schuurhuis, Jeroen J Lammerts van Bueren, Esther C W Breij, Ignace Vergote
Systematic study of tissue factor expression in solid tumors. Cancer reports (Hoboken, N.J.) 6 (2) (2022)
Johann S de Bono, Jeffrey R Harris, Saskia M Burm, Adriaan Vanderstichele, Mischa A Houtkamp, Saida Aarass, Ruth Riisnaes, Ines Figueiredo, Daniel Nava Rodrigues, Rossitza Christova, Siel Olbrecht, Hans W M Niessen, Sigrid R Ruuls, Danita H Schuurhuis, Jeroen J Lammerts van Bueren, Esther C W Breij, Ignace Vergote
Systematic study of tissue factor expression in solid tumors. Cancer reports (Hoboken, N.J.) 6 (2) (2022)
Maha Hussain, Claire Corcoran, Caroline Sibilla, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Joaquin Mateo, David Olmos, Niven Mehra, Michael P Kolinsky, Guilhem Roubaud, Mustafa Özgüroǧlu, Nobuaki Matsubara, Craig Gedye, Young Deuk Choi, Charles Padua, Alexander Kohlmann, Robert Huisden, Julia A Elvin, Jinyu Kang, Carrie A Adelman, Allison Allen, Christian Poehlein, Johann S de Bono
Tumor Genomic Testing for >4,000 Men with Metastatic Castration-resistant Prostate Cancer in the Phase III Trial PROfound (Olaparib). Clinical cancer research : an official journal of the American Association for Cancer Research 28 (8) (2022)
Pamela J Maxwell, Melanie McKechnie, Christopher W Armstrong, Judith M Manley, Chee Wee Ong, Jenny Worthington, Ian G Mills, Daniel B Longley, James P Quigley, Amina Zoubeidi, Johann S de Bono, Elena Deryugina, Melissa J LaBonte, David J J Waugh
Attenuating Adaptive VEGF-A and IL8 Signaling Restores Durable Tumor Control in AR Antagonist-Treated Prostate Cancers. Molecular cancer research : MCR 20 (6) (2022)
Atish D Choudhury, Celestia S Higano, Johann S de Bono, Natalie Cook, Dana E Rathkopf, Kari B Wisinski, Juan Martin-Liberal, Mark Linch, Elisabeth I Heath, Richard D Baird, Javier García Corbacho, Miguel Quintela-Fandino, Simon T Barry, Elza C de Bruin, Steve Colebrook, George Hawkins, Teresa Klinowska, Brijesh Maroj, Ganesh Moorthy, Peter G S Mortimer, Michele Moschetta, Myria Nikolaou, Liz Sainsbury, Geoffrey I Shapiro, Lillian L Siu, Aaron Richard Hansen
A Phase I Study Investigating AZD8186, a Potent and Selective Inhibitor of PI3Kβ/δ, in Patients with Advanced Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research 28 (11) (2022)
Nobuaki Matsubara, Johann S de Bono, David Olmos, Giuseppe Procopio, Satoru Kawakami, Yuksel Urun, Robbert van Alphen, Aude Flechon, Michael A Carducci, Young Deuk Choi, Sebastien J Hotte, Ernesto Korbenfeld, Gero Kramer, Archana M Agarwal, Kim N Chi, Simon Dearden, Christopher Gresty, Jinyu Kang, Christian Poehlein, Elizabeth A Harrington, Maha H A Hussain
Olaparib Efficacy in Patients with Metastatic Castration-resistant Prostate Cancer and BRCA1, BRCA2 or ATM Alterations Identified by Testing Circulating Tumor DNA. Clinical cancer research : an official journal of the American Association for Cancer Research (2022)
Suzanne Carreira, Nuria Porta, Sara Arce-Gallego, George Seed, Alba Llop-Guevara, Diletta Bianchini, Pasquale Rescigno, Alec Paschalis, Claudia Bertan, Chloe Baker, Jane Goodall, Susana Miranda, Ruth Riisnaes, Ines Figueiredo, Ana Ferreira, Rita Pereira, Mateus Crespo, Bora Gurel, Daniel Nava Rodrigues, Stephen J Pettitt, Wei Yuan, Violeta Serra, Jan Rekowski, Christopher J Lord, Emma C Hall, Joaquin Mateo, Johann S de Bono
Biomarkers Associating with PARP Inhibitor Benefit in Prostate Cancer in the TOPARP-B Trial. Cancer discovery 11 (11) (2021)
Aude De Gassart, Kieu-Suong Le, Patrick Brune, Sophie Agaugué, Jennifer Sims, Armelle Goubard, Rémy Castellano, Noémie Joalland, Emmanuel Scotet, Yves Collette, Emmanuel Valentin, Clement Ghigo, Christine Pasero, Magali Colazet, Jaime Guillén, Carla E Cano, Aurélien Marabelle, Johann S de Bono, René Hoet, Alemseged Truneh, Daniel Olive, Paul A Frohna
Development of ICT01, a first-in-class, anti-BTN3A antibody for activating Vγ9Vδ2 T cell-mediated antitumor immune response. Science translational medicine 13 (616) (2021)
Yi Liang, Sujeeve Jeganathan, Stefano Marastoni, Adam Sharp, Ines Figueiredo, Richard Marcellus, Amanda Mawson, Zvi Shalev, Aleksandra Pesic, Joan Sweet, Haiyang Guo, David Uehling, Bora Gurel, Antje J Neeb, Housheng Hansen He, Bruce Montgomery, Marianne Koritzinsky, Samantha Richelle Oakes, Johann S de Bono, Martin Gleave, Amina Zoubeidi, Bradly G Wouters, Anthony M Joshua
Emergence of Enzalutamide Resistance in Prostate Cancer is Associated with BCL-2 and IKKB Dependencies. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (8) (2021)
Debashis Sarker, Nancy A Dawson, Ana M Aparicio, Tanya B Dorff, Allan J Pantuck, Ulka N Vaishampayan, Lynn Henson, Lakshmi Vasist, Sumita Roy-Ghanta, Michele Gorczyca, Whitney York, Gopinath Ganji, Jerry Tolson, Johann S de Bono
A Phase I, Open-Label, Dose-Finding Study of GSK2636771, a PI3Kβ Inhibitor, Administered with Enzalutamide in Patients with Metastatic Castration-Resistant Prostate Cancer. Clinical cancer research : an official journal of the American Association for Cancer Research (2021)
Abhijit Pal, Rajiv Shinde, Manuel Selvi Miralles, Paul Workman, Johann S de Bono
Applications of liquid biopsy in the Pharmacological Audit Trail for anticancer drug development. Nature reviews. Clinical oncology 18 (7) (2021)
Jonathan Welti, Adam Sharp, Nigel Brooks, Wei Yuan, Christopher McNair, Saswati N Chand, Abhijit Pal, Ines Figueiredo, Ruth Riisnaes, Bora Gurel, Jan Rekowski, Denisa Bogdan, William West, Barbara Young, Meera Raja, Amy Prosser, Jordan Lane, Stuart Thomson, Jenny Worthington, Stuart Onions, Jonathan Shannon, Silvia Paoletta, Richard Brown, Don Smyth, Gareth W Harbottle, Veronica S Gil, Susana Miranda, Mateus Crespo, Ana Ferreira, Rita Pereira, Nina Tunariu, Suzanne Carreira, Antje J Neeb, Jian Ning, Amanda Swain, David Taddei, null null, Matthew J Schiewer, Karen E Knudsen, Neil Pegg, Johann S de Bono
Targeting the p300/CBP Axis in Lethal Prostate Cancer. Cancer discovery 11 (5) (2021)
Nicolò Pernigoni, Elena Zagato, Arianna Calcinotto, Martina Troiani, Ricardo Pereira Mestre, Bianca Calì, Giuseppe Attanasio, Jacopo Troisi, Mirko Minini, Simone Mosole, Ajinkya Revandkar, Emiliano Pasquini, Angela Rita Elia, Daniela Bossi, Andrea Rinaldi, Pasquale Rescigno, Penny Flohr, Joanne Hunt, Antje Neeb, Lorenzo Buroni, Christina Guo, Jonathan Welti, Matteo Ferrari, Matteo Grioni, Josée Gauthier, Raad Z Gharaibeh, Anna Palmisano, Gladys Martinetti Lucchini, Eugenia D'Antonio, Sara Merler, Marco Bolis, Fabio Grassi, Ernesto Di Cesare, Maria Teresa Sabrina Bertilaccio, Alberto Briganti, Maria Rescigno, Jean-Philippe Theurillat, Christian Jobin, Silke Gillessen Sommer, Johann S de Bono, Andrea Alimonti
Commensal bacteria promote endocrine resistance in prostate cancer through androgen biosynthesis. Science (New York, N.Y.) 374 (6564) (2021)
Amy C Mandigo, Ayesha A Shafi, Jennifer J McCann, Wei Yuan, Talya S Laufer, Denisa Bogdan, Lewis Gallagher, Emanuela Dylgjeri, Galina Semenova, Irina A Vasilevskaya, Matthew J Schiewer, Christopher M McNair, Johann S de Bono, Karen E Knudsen
Novel oncogenic transcription factor cooperation in RB-deficient cancer. Cancer research (2021)
Johann S de Bono, Mark T Fleming, Judy S Wang, Richard Cathomas, Manuel Selvi Miralles, John Bothos, Mary Jane Hinrichs, Qu Zhang, Peng He, Marna Williams, Anton I Rosenbaum, Meina Liang, Kapil Vashisht, Song Cho, Pablo Martinez, Daniel P Petrylak
Phase I Study of MEDI3726: A Prostate-Specific Membrane Antigen-Targeted Antibody-Drug Conjugate, in Patients with mCRPC after Failure of Abiraterone or Enzalutamide. Clinical cancer research : an official journal of the American Association for Cancer Research 27 (13) (2021)
Amy C Mandigo, Wei Yuan, Kexin Xu, Peter Gallagher, Angel Pang, Yi Fang Guan, Ayesha A Shafi, Chellappagounder Thangavel, Beshara Sheehan, Denisa Bogdan, Alec Paschalis, Jennifer J McCann, Talya S Laufer, Nicolas Gordon, Irina A Vasilevskaya, Emanuela Dylgjeri, Saswati N Chand, Matthew J Schiewer, Josep Domingo-Domenech, Robert B Den, Jeff Holst, Peter A McCue, Johann S de Bono, Christopher M McNair, Karen E Knudsen
RB/E2F1 as a Master Regulator of Cancer Cell Metabolism in Advanced Disease. Cancer discovery 11 (9) (2021)
Alec Paschalis, Jonathan Welti, Antje J Neeb, Wei Yuan, Ines Figueiredo, Rita Pereira, Ana Ferreira, Ruth Riisnaes, Daniel Nava Rodrigues, Juan M Jiménez-Vacas, Soojin Kim, Takuma Uo, Patrizio Di Micco, Anthony Tumber, Md Saiful Islam, Marc A Moesser, Martine I Abboud, Akane Kawamura, Bora Gurel, Rossitza Christova, Veronica S Gil, Lorenzo Buroni, Mateus Crespo, Susana Miranda, Maryou B Lambros, Suzanne Carreira, Nina Tunariu, Andrea Alimonti, Bissan Al-Lazikani, Christopher J Schofield, Stephen R Plymate, Adam Sharp, Johann S de Bono, null null
JMJD6 Is a Druggable Oxygenase That Regulates AR-V7 Expression in Prostate Cancer. Cancer research 81 (4) (2021)
Veronica S Gil, Susana Miranda, Ruth Riisnaes, Bora Gurel, Mariantonietta D'Ambrosio, Alessandro Vasciaveo, Mateus Crespo, Ana Ferreira, Daniela Brina, Martina Troiani, Adam Sharp, Beshara Sheehan, Rossitza Christova, George Seed, Ines Figueiredo, Maryou Lambros, David Dolling, Jan Rekowski, Abdullah Alajati, Matthew Clarke, Rita Pereira, Penelope Ruth Flohr, Gemma Fowler, Gunther Boysen, Semini Sumanasuriya, Diletta Bianchini, Pasquale Rescigno, Caterina Aversa, Nina Tunariu, Christina Guo, Alec Paschalis, Claudia Bertan, Lorenzo Buroni, Jian Ning, Suzanne Carreira, Paul Workman, Amanda Swain, Andrea Califano, Michael M Shen, Andrea Alimonti, Antje J Neeb, Stand Up To Cancer International Prostate Cancer Dream Team, Jonathan Welti, Wei Yuan, Johann S de Bono
HER3 is an Actionable Target in Advanced Prostate Cancer. Cancer research (2021)
Johann S de Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, A Oliver Sartor, Neeraj Agarwal, David Olmos, Antoine Thiery-Vuillemin, Przemyslaw Twardowski, Niven Mehra, Carsten Goessl, Jinyu Kang, Joseph Burgents, Wenting Wu, Alexander Kohlmann, Carrie A Adelman, Maha Hussain
Olaparib for Metastatic Castration-Resistant Prostate Cancer. The New England journal of medicine 382 (22) (2020)
Johann S de Bono, Joaquin Mateo, Karim Fizazi, Fred Saad, Neal Shore, Shahneen Sandhu, Kim N Chi, A Oliver Sartor, Neeraj Agarwal, David Olmos, Antoine Thiery-Vuillemin, Przemyslaw Twardowski, Guilhem Roubaud, Mustafa Özgüroğlu, Jinyu Kang, Joseph Burgents, Christopher Gresty, Claire Corcoran, Carrie A Adelman, null null
Survival with Olaparib in Metastatic Castration-Resistant Prostate Cancer. The New England journal of medicine 383 (24) (2020)
Johann S de Bono, Christina Guo, Bora Gurel, Angelo M De Marzo, Karen S Sfanos, Ram S Mani, Jesús Gil, Charles G Drake, Andrea Alimonti
Prostate carcinogenesis: inflammatory storms. Nature reviews. Cancer 20 (8) (2020)
Alec Paschalis, Adam Sharp, Jonathan C Welti, Antje Neeb, Ganesh V Raj, Jun Luo, Stephen R Plymate, Johann S de Bono
Alternative splicing in prostate cancer. Nature reviews. Clinical oncology 15 (11) (2019)
Ronald de Wit, Johann S de Bono, Cora N Sternberg, Karim Fizazi, Bertrand Tombal, Christian Wülfing, Gero Kramer, Jean-Christophe Eymard, Aristotelis Bamias, Joan Carles, Roberto Iacovelli, Bohuslav Melichar, Ásgerður Sverrisdóttir, Christine Theodore, Susan Feyerabend, Carole Helissey, Ayse Ozatilgan, Christine Geffriaud-Ricouard, Daniel Castellano, null null
Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer. The New England journal of medicine 381 (26) (2019)
Raquel Perez-Lopez, Nina Tunariu, Anwar R Padhani, Wim J G Oyen, Stefano Fanti, Hebert Alberto Vargas, Aurelius Omlin, Michael J Morris, Johann S de Bono, Dow-Mu Koh
Imaging Diagnosis and Follow-up of Advanced Prostate Cancer: Clinical Perspectives and State of the Art. Radiology 292 (2) (2019)
Pasquale Rescigno, Johann S de Bono
Immunotherapy for lethal prostate cancer. Nature reviews. Urology 16 (2) (2019)
Joshua Armenia, Stephanie A M Wankowicz, David Liu, Jianjiong Gao, Ritika Kundra, Ed Reznik, Walid K Chatila, Debyani Chakravarty, G Celine Han, Ilsa Coleman, Bruce Montgomery, Colin Pritchard, Colm Morrissey, Christopher E Barbieri, Himisha Beltran, Andrea Sboner, Zafeiris Zafeiriou, Susana Miranda, Craig M Bielski, Alexander V Penson, Charlotte Tolonen, Franklin W Huang, Dan Robinson, Yi Mi Wu, Robert Lonigro, Levi A Garraway, Francesca Demichelis, Philip W Kantoff, Mary-Ellen Taplin, Wassim Abida, Barry S Taylor, Howard I Scher, Peter S Nelson, Johann S de Bono, Mark A Rubin, Charles L Sawyers, Arul M Chinnaiyan, null null, Nikolaus Schultz, Eliezer Van Allen
The long tail of oncogenic drivers in prostate cancer. Nature genetics 50 (5) (2018)
A H Bryce, J J Alumkal, Andrew J Armstrong, C S Higano, P Iversen, C N Sternberg, D Rathkopf, Y Loriot, Johann S de Bono, B Tombal, S Abhyankar, P Lin, A Krivoshik, D Phung, T M Beer
Radiographic progression with nonrising PSA in metastatic castration-resistant prostate cancer: post hoc analysis of PREVAIL. Prostate cancer and prostatic diseases 20 (2) (2017)