John D Scott

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 28

Top Topics

Molecular Docking

Acute Lymphoblastic Leukemia

Top Venues

Science advances

bioRxiv : the preprint server for biology

The Journal of biological chemistry

This page only lists publications with an associated author ORCID identifier.

Publications

Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Nicole M Marsh, Melissa J S MacEwen, Jane Chea, Heidi L Kenerson, Albert A Kwong, Timothy M Locke, Francisco Javier Miralles, Tanmay Sapre, Natasha Gozali, Gunes Ekin Atilla-Gokcumen, Shao-En Ong, John D Scott, Raymond S Yeung, Yasemin Sancak
Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Nicole M Marsh, Melissa J S MacEwen, Jane Chea, Heidi L Kenerson, Albert A Kwong, Timothy M Locke, Francisco Javier Miralles, Tanmay Sapre, Natasha Gozali, Gunes Ekin Atilla-Gokcumen, Shao-En Ong, John D Scott, Raymond S Yeung, Yasemin Sancak
Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Nicole M Marsh, Melissa J S MacEwen, Jane Chea, Heidi L Kenerson, Albert A Kwong, Timothy M Locke, Francisco Javier Miralles, Tanmay Sapre, Natasha Gozali, Gunes Ekin Atilla-Gokcumen, Shao-En Ong, John D Scott, Raymond S Yeung, Yasemin Sancak
Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife 12 (2023)
Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife 12 (2023)
Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife 12 (2023)
Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife 12 (2023)
Sophia M Lauer, Mitchell H Omar, Martin G Golkowski, Heidi L Kenerson, Bryan C Pascual, Katherine Forbush, F Donelson Smith, John Gordan, Shao-En Ong, Raymond S Yeung, John D Scott
Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma. bioRxiv : the preprint server for biology (2023)
Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, Phuong Vu, Krushna C Patra, Mehdi Bouhaddou, Heidi L Kenerson, Huat C Lim, Donald Long, Raymond S Yeung, Praveen Sethupathy, Danielle L Swaney, Nevan J Krogan, Rigney E Turnham, Kimberly J Riehle, John D Scott, Nabeel Bardeesy, John D Gordan
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms. eLife 12 (2023)
Kerrie B Collins, John D Scott
Phosphorylation, compartmentalization, and cardiac function. IUBMB life (2022)
Janani Gopalan, Mitchell H Omar, Ankita Roy, Nelly M Cruz, Jerome Falcone, Kiana N Jones, Katherine A Forbush, Jonathan Himmelfarb, Benjamin S Freedman, John D Scott
Targeting an anchored phosphatase-deacetylase unit restores renal ciliary homeostasis. eLife 10 (2021)
Lisa Watson, Tanya N Soliman, Khalil Davis, Joanna Kelly, Nicola Lockwood, Xiaoping Yang, Steven Lynham, John D Scott, Victoria Crossland, Neil Q McDonald, David J Mann, Alan Armstrong, Ulrike Eggert, Peter J Parker
Co-ordinated control of the Aurora B abscission checkpoint by PKCε complex assembly, midbody recruitment and retention. The Biochemical journal 478 (12) (2021)
Laura Gabrovsek, Kerrie B Collins, Stacey Aggarwal, Lauren M Saunders, Ho-Tak Lau, Danny Suh, Yasemin Sancak, Cole Trapnell, Shao-En Ong, F Donelson Smith, John D Scott
A-kinase-anchoring protein 1 (dAKAP1)-based signaling complexes coordinate local protein synthesis at the mitochondrial surface. The Journal of biological chemistry 295 (31) (2020)
Paula J Bucko, Chloe K Lombard, Lindsay Rathbun, Irvin Garcia, Akansha Bhat, Linda Wordeman, F Donelson Smith, Dustin J Maly, Heidi Hehnly, John D Scott
Subcellular drug targeting illuminates local kinase action. eLife 8 (2019)
Rigney E Turnham, F Donelson Smith, Heidi L Kenerson, Mitchell H Omar, Martin Golkowski, Irvin Garcia, Renay Bauer, Ho-Tak Lau, Kevin M Sullivan, Lorene K Langeberg, Shao-En Ong, Kimberly J Riehle, Raymond S Yeung, John D Scott
An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma. eLife 8 (2019)
F Donelson Smith, John D Scott
Protein kinase A activation: Something new under the sun? The Journal of cell biology 217 (6) (2018)
F Donelson Smith, Jessica L Esseltine, Patrick J Nygren, David Veesler, Dominic P Byrne, Matthias Vonderach, Ilya Strashnov, Claire E Eyers, Patrick A Eyers, Lorene K Langeberg, John D Scott
Local protein kinase A action proceeds through intact holoenzymes. Science (New York, N.Y.) 356 (6344) (2018)
Stacey Aggarwal, Laura Gabrovsek, Lorene K Langeberg, Martin Golkowski, Shao-En Ong, F Donelson Smith, John D Scott
Depletion of dAKAP1-protein kinase A signaling islands from the outer mitochondrial membrane alters breast cancer cell metabolism and motility. The Journal of biological chemistry 294 (9) (2018)
Jennifer L Sanderson, John D Scott, Mark L Dell'Acqua
Control of Homeostatic Synaptic Plasticity by AKAP-Anchored Kinase and Phosphatase Regulation of Ca2+-Permeable AMPA Receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience 38 (11) (2018)
F Donelson Smith, Mitchell H Omar, Patrick J Nygren, Joseph Soughayer, Naoto Hoshi, Ho-Tak Lau, Calvin G Snyder, Tess C Branon, Debapriya Ghosh, Lorene K Langeberg, Alice Y Ting, Luis Fernando Santana, Shao-En Ong, Manuel F Navedo, John D Scott
Single nucleotide polymorphisms alter kinase anchoring and the subcellular targeting of A-kinase anchoring proteins. Proceedings of the National Academy of Sciences of the United States of America 115 (49) (2018)
Patrick J Nygren, Sohum Mehta, Devin K Schweppe, Lorene K Langeberg, Jennifer L Whiting, Chad R Weisbrod, James E Bruce, Jin Zhang, David Veesler, John D Scott
Intrinsic disorder within AKAP79 fine-tunes anchored phosphatase activity toward substrates and drug sensitivity. eLife 6 (2017)