Patrick A Eyers

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 39

Top Venues

bioRxiv : the preprint server for biology

Science advances

Science signaling

The Biochemical journal

University of Dundee (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Dundee Sep 01 1997 - Sep 30 2000

United Kingdom

PHD :: Biochemistry

University of Bristol Oct 01 1994 - Jun 30 1997

United Kingdom

BSC :: Biochemistry

Publications

Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Mitchell H Omar, Dominic P Byrne, Safal Shrestha, Tyler M Lakey, Kyung-Soon Lee, Sophia M Lauer, Kerrie B Collins, Leonard A Daly, Claire E Eyers, Geoffrey Stuart Baird, Shao-En Ong, Natarajan Kannan, Patrick A Eyers, John D Scott
Discovery of a Cushing's syndrome protein kinase A mutant that biases signaling through type I AKAPs. Science advances 10 (8) (2024)
George N Bendzunas, Dominic P Byrne, Safal Shrestha, Leonard A Daly, Sally O Oswald, Samiksha Katiyar, Aarya Venkat, Wayland Yeung, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Redox Regulation of Brain Selective Kinases BRSK1/2: Implications for Dynamic Control of the Eukaryotic AMPK family through Cys-based mechanisms. bioRxiv : the preprint server for biology (2024)
Aarya Venkat, Grace Watterson, Dominic P Byrne, Brady O'Boyle, Safal Shrestha, Nathan Gravel, Emma E Fairweather, Leonard A Daly, Claire Bunn, Wayland Yeung, Ishan Aggarwal, Samiksha Katiyar, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases. bioRxiv : the preprint server for biology (2023)
Aarya Venkat, Grace Watterson, Dominic P Byrne, Brady O'Boyle, Safal Shrestha, Nathan Gravel, Emma E Fairweather, Leonard A Daly, Claire Bunn, Wayland Yeung, Ishan Aggarwal, Samiksha Katiyar, Claire E Eyers, Patrick A Eyers, Natarajan Kannan
Mechanistic and evolutionary insights into isoform-specific 'supercharging' in DCLK family kinases. eLife 12 (2023)
Dominic P Byrne, Safal Shrestha, Leonard A Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E Eyers, Natarajan Kannan, Patrick A Eyers
Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2. The Biochemical journal 480 (2) (2023)
Dominic P Byrne, Safal Shrestha, Leonard A Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E Eyers, Natarajan Kannan, Patrick A Eyers
Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2. The Biochemical journal 480 (2) (2023)
Leonard A Daly, Dominic P Byrne, Simon Perkins, Philip J Brownridge, Euan McDonnell, Andrew R Jones, Patrick A Eyers, Claire E Eyers
Custom Workflow for the Confident Identification of Sulfotyrosine-Containing Peptides and Their Discrimination from Phosphopeptides. Journal of proteome research (2023)
Dominic P Byrne, Safal Shrestha, Leonard A Daly, Vanessa Marensi, Krithika Ramakrishnan, Claire E Eyers, Natarajan Kannan, Patrick A Eyers
Evolutionary and cellular analysis of the 'dark' pseudokinase PSKH2. The Biochemical journal 480 (2) (2023)
Anton Kalyuzhnyy, Patrick A Eyers, Claire E Eyers, Emily Bowler-Barnett, Maria J Martin, Zhi Sun, Eric W Deutsch, Andrew R Jones
Profiling the Human Phosphoproteome to Estimate the True Extent of Protein Phosphorylation. Journal of proteome research 21 (6) (2022)
Lauren J Tomlinson, Matthew Batchelor, Joscelyn Sarsby, Dominic P Byrne, Philip J Brownridge, Richard Bayliss, Patrick A Eyers, Claire E Eyers
Exploring the Conformational Landscape and Stability of Aurora A Using Ion-Mobility Mass Spectrometry and Molecular Modeling. Journal of the American Society for Mass Spectrometry 33 (3) (2022)
Ana S Luis, Chunsheng Jin, Gabriel Vasconcelos Pereira, Robert W P Glowacki, Sadie R Gugel, Shaleni Singh, Dominic P Byrne, Nicholas A Pudlo, James A London, Arnaud Baslé, Mark Reihill, Stefan Oscarson, Patrick A Eyers, Mirjam Czjzek, Gurvan Michel, Tristan Barbeyron, Edwin A Yates, Gunnar C Hansson, Niclas G Karlsson, Alan Cartmell, Eric C Martens
A single sulfatase is required to access colonic mucin by a gut bacterium. Nature 598 (7880) (2021)
Safal Shrestha, Samiksha Katiyar, Carlos E Sanz-Rodriguez, Nolan R Kemppinen, Hyun W Kim, Renuka Kadirvelraj, Charalampos Panagos, Neda Keyhaninejad, Maxwell Colonna, Pradeep Chopra, Dominic P Byrne, Geert-Jan Boons, Esther van der Knaap, Patrick A Eyers, Arthur S Edison, Zachary A Wood, Natarajan Kannan
A redox-active switch in fructosamine-3-kinases expands the regulatory repertoire of the protein kinase superfamily. Science signaling 13 (639) (2020)
Safal Shrestha, Dominic P Byrne, John A Harris, Natarajan Kannan, Patrick A Eyers
Cataloguing the dead: breathing new life into pseudokinase research. The FEBS journal 287 (19) (2020)
Dominic P Byrne, Safal Shrestha, Martin Galler, Min Cao, Leonard A Daly, Amy E Campbell, Claire E Eyers, Elizabeth A Veal, Natarajan Kannan, Patrick A Eyers
Aurora A regulation by reversible cysteine oxidation reveals evolutionarily conserved redox control of Ser/Thr protein kinase activity. Science signaling 13 (639) (2020)
Annie Kwon, Steven Scott, Rahil Taujale, Wayland Yeung, Krys J Kochut, Patrick A Eyers, Natarajan Kannan
Tracing the origin and evolution of pseudokinases across the tree of life. Science signaling 12 (578) (2019)
Antonio J M Ribeiro, Sayoni Das, Natalie Dawson, Rossana Zaru, Sandra E Orchard, Janet M Thornton, Christine Orengo, Elton Zeqiraj, James G Murphy, Patrick A Eyers
Emerging concepts in pseudoenzyme classification, evolution, and signaling. Science signaling 12 (594) (2019)
Gemma Hardman, Simon Perkins, Philip J Brownridge, Christopher J Clarke, Dominic P Byrne, Amy E Campbell, Anton Kalyuzhnyy, Ashleigh Myall, Patrick A Eyers, Andrew R Jones, Claire E Eyers
Strong anion exchange-mediated phosphoproteomics reveals extensive human non-canonical phosphorylation. The EMBO journal 38 (21) (2019)
Neil M Kershaw, Dominic P Byrne, Hollie Parsons, Neil G Berry, David G Fernig, Patrick A Eyers, Richard Cosstick
Structure-based design of nucleoside-derived analogues as sulfotransferase inhibitors. RSC advances 9 (55) (2019)
F Donelson Smith, Jessica L Esseltine, Patrick J Nygren, David Veesler, Dominic P Byrne, Matthias Vonderach, Ilya Strashnov, Claire E Eyers, Patrick A Eyers, Lorene K Langeberg, John D Scott
Local protein kinase A action proceeds through intact holoenzymes. Science (New York, N.Y.) 356 (6344) (2018)
Daniel M Foulkes, Dominic P Byrne, Wayland Yeung, Safal Shrestha, Fiona P Bailey, Samantha Ferries, Claire E Eyers, Karen Keeshan, Carrow I Wells, David Harold Drewry, William J Zuercher, Natarajan Kannan, Patrick A Eyers
Covalent inhibitors of EGFR family protein kinases induce degradation of human Tribbles 2 (TRIB2) pseudokinase in cancer cells. Science signaling 11 (549) (2018)
Dominic P Byrne, Yong Li, Krithika Ramakrishnan, Igor L Barsukov, Edwin Alexander Yates, Claire E Eyers, Dulcé Papy-Garcia, Sandrine Chantepie, Vijayakanth Pagadala, Jian Liu, Carrow I Wells, David Harold Drewry, William J Zuercher, Neil G Berry, David G Fernig, Patrick A Eyers
New tools for carbohydrate sulfation analysis: heparan sulfate 2-O-sulfotransferase (HS2ST) is a target for small-molecule protein kinase inhibitors. The Biochemical journal 475 (15) (2018)
Dominic P Byrne, Yong Li, Pawin Ngamlert, Krithika Ramakrishnan, Claire E Eyers, Carrow I Wells, David Harold Drewry, William J Zuercher, Neil G Berry, David G Fernig, Patrick A Eyers
New tools for evaluating protein tyrosine sulfation: tyrosylprotein sulfotransferases (TPSTs) are novel targets for RAF protein kinase inhibitors. The Biochemical journal 475 (15) (2018)
Patrick A Eyers
A new consensus for evaluating CDKL5/STK9-dependent signalling mechanisms. The EMBO journal 37 (24) (2018)
Leah Bury, Paula Almeida Coelho, Angela Simeone, Samantha Ferries, Claire E Eyers, Patrick A Eyers, Magdalena Zernicka-Goetz, David M Glover
Plk4 and Aurora A cooperate in the initiation of acentriolar spindle assembly in mammalian oocytes. The Journal of cell biology 216 (11) (2017)
Samantha Ferries, Simon Perkins, Philip J Brownridge, Amy Campbell, Patrick A Eyers, Andrew R Jones, Claire E Eyers
Evaluation of Parameters for Confident Phosphorylation Site Localization Using an Orbitrap Fusion Tribrid Mass Spectrometer. Journal of proteome research 16 (9) (2017)
Fiona P Bailey, Kim Clarke, Helen Kalirai, Jenna Kenyani, Haleh Shahidipour, Francesco Falciani, Judy M Coulson, Joseph J Sacco, Sarah E Coupland, Patrick A Eyers
Kinome-wide transcriptional profiling of uveal melanoma reveals new vulnerabilities to targeted therapeutics. Pigment cell & melanoma research 31 (2) (2017)
Ruzica Bago, Eeva Sommer, Pau Castel, Claire Crafter, Fiona P Bailey, Natalia Shpiro, José Baselga, Darren Cross, Patrick A Eyers, Dario R Alessi
The hVps34-SGK3 pathway alleviates sustained PI3K/Akt inhibition by stimulating mTORC1 and tumour growth. The EMBO journal 35 (17) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Patrick A Eyers