Dustin J Maly

ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 44

Top Venues

ACS chemical biology

bioRxiv : the preprint server for biology

Molecular cancer therapeutics

Nature chemical biology

UW, Seattle

This page only lists publications with an associated author ORCID identifier.

Affiliation History

UW, Seattle Sep 01 2006

United States

Professor :: Chemistry

Publications

Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn S Epilepsia, Bulathsinhalage Gayani Kanchana Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Vicky L Sun, Samuel L M Arnold, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound That Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular cancer therapeutics 23 (7) (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn S Epilepsia, Bulathsinhalage Gayani Kanchana Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Vicky L Sun, Samuel L M Arnold, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular cancer therapeutics (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn S Epilepsia, Bulathsinhalage Gayani Kanchana Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Vicky L Sun, Samuel L M Arnold, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound That Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular cancer therapeutics 23 (7) (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Jason Z Zhang, Shao-En Ong, Julien S Baker, Dustin J Maly
Single-cell sensor analyses reveal signaling programs enabling Ras-G12C drug resistance. Nature chemical biology (2024)
Jason Z Zhang, William H Nguyen, Nathan Greenwood, John C Rose, Shao-En Ong, Dustin J Maly, Julien S Baker
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution. Nature biotechnology (2024)
Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn S Epilepsia, Bulathsinhalage Gayani Kanchana Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Vicky L Sun, Samuel L M Arnold, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular cancer therapeutics (2024)
Jessica J Simon, Douglas M Fowler, Dustin J Maly
Multiplexed, multimodal profiling of the intracellular activity, interactions, and druggability of protein variants using LABEL-seq. bioRxiv : the preprint server for biology (2024)
Jason Z Zhang, Shao-En Ong, Julien S Baker, Dustin J Maly
Single-cell sensor analyses reveal signaling programs enabling Ras-G12C drug resistance. Nature chemical biology (2024)
Jason Z Zhang, William H Nguyen, Nathan Greenwood, John C Rose, Shao-En Ong, Dustin J Maly, Julien S Baker
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution. Nature biotechnology (2024)
Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn S Epilepsia, Bulathsinhalage Gayani Kanchana Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Vicky L Sun, Samuel L M Arnold, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound That Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular cancer therapeutics 23 (7) (2024)
Jason Z Zhang, William H Nguyen, Nathan Greenwood, John C Rose, Shao-En Ong, Dustin J Maly, Julien S Baker
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution. Nature biotechnology (2024)
Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn S Epilepsia, Bulathsinhalage Gayani Kanchana Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Vicky L Sun, Samuel L M Arnold, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound That Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. Molecular cancer therapeutics 23 (7) (2024)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology 18 (2) (2023)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology 18 (2) (2023)
Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler
A chemically controlled Cas9 switch enables temporal modulation of diverse effectors. Nature chemical biology (2023)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology 18 (2) (2023)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology 18 (2) (2023)
Jason Z Zhang, Shao-En Ong, Julien S Baker, Dustin J Maly
Single-cell signaling analysis reveals that Major Vault Protein facilitates RasG12C inhibitor resistance. bioRxiv : the preprint server for biology (2023)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology (2023)
Takuma Uo, Kayode K Ojo, Cynthia C T Sprenger, Kathryn Soriano Epilepsia, B Gayani K Perera, Mamatha Damodarasamy, Shihua Sun, Soojin Kim, Hannah R Hapner Hogan, Matthew A Hulverson, Ryan Choi, Grant R Whitman, Lynn K Barrett, Samantha A Michaels, Linda H Xu, Haley J Pang, Matthew M Nguyen, Anna-Lena B G Vigil, Varun Kamat, Lucas B Sullivan, Ian R Sweet, Ram Vidadala, Dustin J Maly, Wesley C Van Voorhis, Stephen R Plymate
A Compound that Inhibits Glycolysis in Prostate Cancer Controls Growth of Advanced Prostate Cancer. bioRxiv : the preprint server for biology (2023)
Cindy T Wei, Nicholas A Popp, Omri Peleg, Rachel L Powell, Elhanan Borenstein, Dustin J Maly, Douglas M Fowler
A chemically controlled Cas9 switch enables temporal modulation of diverse effectors. Nature chemical biology (2023)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology 18 (2) (2023)
Carrie S Tambo, Sarvind M Tripathi, B Gayani K Perera, Dustin J Maly, Alexander J Bridges, Gert Kiss, Seth M Rubin
Biolayer Interferometry Assay for Cyclin-Dependent Kinase-Cyclin Association Reveals Diverse Effects of Cdk2 Inhibitors on Cyclin Binding Kinetics. ACS chemical biology 18 (2) (2023)
Hannah C Feldman, Rajarshi Ghosh, Vincent C Auyeung, James L Mueller, Jae-Hong Kim, Zachary E Potter, Venkata N Vidadala, B Gayani K Perera, Alina Olivier, Bradley J Backes, Julie Zikherman, Feroz R Papa, Dustin J Maly
ATP-competitive partial antagonists of the IRE1α RNase segregate outputs of the UPR. Nature chemical biology 17 (11) (2021)
Matthew A Hulverson, Ryan Choi, Rama S R Vidadala, Grant R Whitman, Venkata Narayana Vidadala, Kayode K Ojo, Lynn K Barrett, James J Lynch, Kennan Marsh, Dale J Kempf, Dustin J Maly, Wesley C Van Voorhis
Pyrrolopyrimidine Bumped Kinase Inhibitors for the Treatment of Cryptosporidiosis. ACS infectious diseases 7 (5) (2021)
Linglan Fang, Jessica Vilas-Boas, Sujata Chakraborty, Zachary E Potter, Ames C Register, Markus A Seeliger, Dustin J Maly
How ATP-Competitive Inhibitors Allosterically Modulate Tyrosine Kinases That Contain a Src-like Regulatory Architecture. ACS chemical biology 15 (7) (2020)
Martin Golkowski, Venkata Narayana Vidadala, Ho-Tak Lau, Anna Shoemaker, Masami Shimizu-Albergine, Joseph Beavo, Dustin J Maly, Shao-En Ong
Kinobead/LC-MS Phosphokinome Profiling Enables Rapid Analyses of Kinase-Dependent Cell Signaling Networks. Journal of proteome research 19 (3) (2020)
John C Rose, Nicholas A Popp, Christopher D Richardson, Jason J Stephany, Julie Mathieu, Cindy T Wei, Jacob E Corn, Dustin J Maly, Douglas M Fowler
Suppression of unwanted CRISPR-Cas9 editing by co-administration of catalytically inactivating truncated guide RNAs. Nature communications 11 (1) (2020)
Sujata Chakraborty, Takayuki Inukai, Linglan Fang, Martin Golkowski, Dustin J Maly
Targeting Dynamic ATP-Binding Site Features Allows Discrimination between Highly Homologous Protein Kinases. ACS chemical biology 14 (6) (2019)
Hannah C Feldman, Venkata Narayana Vidadala, Zachary E Potter, Feroz R Papa, Bradley J Backes, Dustin J Maly
Development of a Chemical Toolset for Studying the Paralog-Specific Function of IRE1. ACS chemical biology 14 (12) (2019)
Paula J Bucko, Chloe K Lombard, Lindsay Rathbun, Irvin Garcia, Akansha Bhat, Linda Wordeman, F Donelson Smith, Dustin J Maly, Heidi Hehnly, John D Scott
Subcellular drug targeting illuminates local kinase action. eLife 8 (2019)
Linglan Fang, Sujata Chakraborty, Emily M Dieter, Zachary E Potter, Chloe K Lombard, Dustin J Maly
Chemoproteomic Method for Profiling Inhibitor-Bound Kinase Complexes. Journal of the American Chemical Society 141 (30) (2019)
Glenna Wink Foight, Zhizhi Wang, Cindy T Wei, Per Jr Greisen, Katrina M Warner, Daniel Cunningham-Bryant, Keunwan Park, T J Brunette, William Sheffler, David Baker, Dustin J Maly
Multi-input chemical control of protein dimerization for programming graded cellular responses. Nature biotechnology 37 (10) (2019)
Daniel Cunningham-Bryant, Emily M Dieter, Glenna W Foight, John C Rose, Dana E Loutey, Dustin J Maly
A Chemically Disrupted Proximity System for Controlling Dynamic Cellular Processes. Journal of the American Chemical Society 141 (8) (2019)
Chloe K Lombard, Audrey L Davis, Takayuki Inukai, Dustin J Maly
Allosteric Modulation of JNK Docking Site Interactions with ATP-Competitive Inhibitors. Biochemistry 57 (40) (2018)
Rama S R Vidadala, Martin Golkowski, Matthew A Hulverson, Ryan Choi, Molly C McCloskey, Grant R Whitman, Wenlin Huang, Samuel L M Arnold, Lynn K Barrett, Erkang Fan, Ethan A Merritt, Wesley C Van Voorhis, Kayode K Ojo, Dustin J Maly
7 H-Pyrrolo[2,3- d]pyrimidin-4-amine-Based Inhibitors of Calcium-Dependent Protein Kinase 1 Have Distinct Inhibitory and Oral Pharmacokinetic Characteristics Compared with 1 H-Pyrazolo[3,4- d]pyrimidin-4-amine-Based Inhibitors. ACS infectious diseases 4 (4) (2018)
John C Rose, Jason J Stephany, William J Valente, Bridget M Trevillian, Ha V Dang, Jason H Bielas, Dustin J Maly, Douglas M Fowler
Rapidly inducible Cas9 and DSB-ddPCR to probe editing kinetics. Nature methods 14 (9) (2017)
John C Rose, Jason J Stephany, Cindy T Wei, Douglas M Fowler, Dustin J Maly
Rheostatic Control of Cas9-Mediated DNA Double Strand Break (DSB) Generation and Genome Editing. ACS chemical biology 13 (2) (2017)

Dustin J Maly.css-eqlu8i{font-size:small;padding-left:4px;}

Publication Activity (10 Years)

Top Topics

Top Venues

Dustin J Maly