Jon E Hawkinson (Jon Hawkinson)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 16

Top Topics

Structural Basis

Tyrosine Kinase

Papillary Thyroid

Top Venues

Journal of medicinal chemistry

ACS chemical biology

ACS chemical neuroscience

This page only lists publications with an associated author ORCID identifier.

Publications

Deepti Mudaliar, Rachel H Mansky, Angel White, Grace Baudhuin, Jon E Hawkinson, Henry L Wong, Michael A Walters, Rocio Gomez-Pastor
Identification of CK2α' selective inhibitors by the screening of an allosteric-kinase-inhibitor-like compound library. bioRxiv : the preprint server for biology (2024)
Deepti Mudaliar, Rachel H Mansky, Angel White, Grace Baudhuin, Jon E Hawkinson, Henry L Wong, Michael A Walters, Rocio Gomez-Pastor
Discovery of a CK2α'-Biased ATP-Competitive Inhibitor from a High-Throughput Screen of an Allosteric-Inhibitor-Like Compound Library. ACS chemical neuroscience 15 (15) (2024)
Deepti Mudaliar, Rachel H Mansky, Angel White, Grace Baudhuin, Jon E Hawkinson, Henry L Wong, Michael A Walters, Rocio Gomez-Pastor
Discovery of a CK2α'-Biased ATP-Competitive Inhibitor from a High-Throughput Screen of an Allosteric-Inhibitor-Like Compound Library. ACS chemical neuroscience (2024)
Deepti Mudaliar, Rachel H Mansky, Angel White, Grace Baudhuin, Jon E Hawkinson, Henry L Wong, Michael A Walters, Rocio Gomez-Pastor
Identification of CK2α' selective inhibitors by the screening of an allosteric-kinase-inhibitor-like compound library. bioRxiv : the preprint server for biology (2024)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry 66 (3) (2023)
Erik B Faber, Luxin Sun, Jian Tang, Emily R Roberts, Sornakala Ganeshkumar, Nan Wang, Damien M Rasmussen, Abir Majumdar, Laura E Hirsch, Kristen John, An Yang, Hira Khalid, Jon E Hawkinson, Nicholas M Levinson, Vargheese M Chennthukuzhi, Daniel A Harki, Ernst K Schonbrunn, Gunda I Georg
Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nature communications 14 (1) (2023)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry 66 (3) (2023)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry 66 (3) (2023)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry (2023)
Erick J Carlson, Rawle Francis, Yutong Liu, Ping Li, Maximilian D Lyon, Celia M Santi, Derek J Hook, Jon E Hawkinson, Gunda I Georg
Discovery and Characterization of Multiple Classes of Human CatSper Blockers. ChemMedChem 17 (15) (2022)
Erik B Faber, Defeng Tian, David Burban, Nicholas M Levinson, Jon E Hawkinson, Gunda I Georg
Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2. ACS chemical biology 15 (7) (2020)
Eyup Akgün, Mary M Lunzer, Defeng Tian, Michael Ansonoff, John Pintar, Daniel Bruce, Jon E Hawkinson, George L Wilcox, Philip S Portoghese
FBNTI, a DOR-Selective Antagonist That Allosterically Activates MOR within a MOR-DOR Heteromer. Biochemistry 60 (18) (2020)
Prakriti Kalra, Logan McGraw, Jennifer R Kimbrough, Anil K Pandey, Jonathan Solberg, Huarui Cui, Anand Divakaran, Kristen John, Jon E Hawkinson, William C K Pomerantz
Quantifying the Selectivity of Protein-Protein and Small Molecule Interactions with Fluorinated Tandem Bromodomain Reader Proteins. ACS chemical biology 15 (11) (2020)
Ali Nakhi, Connor M McDermott, Kristen L Stoltz, Kristen John, Jon E Hawkinson, Elizabeth A Ambrose, Alexander Khoruts, Michael J Sadowsky, Peter I Dosa
7-Methylation of Chenodeoxycholic Acid Derivatives Yields a Substantial Increase in TGR5 Receptor Potency. Journal of medicinal chemistry 62 (14) (2019)
Jon E Hawkinson, Rondedrick Sinville, Deepti Mudaliar, Jagathpala Shetty, Timothy Ward, John C Herr, Gunda I Georg
Potent Pyrimidine and Pyrrolopyrimidine Inhibitors of Testis-Specific Serine/Threonine Kinase 2 (TSSK2). ChemMedChem 12 (22) (2017)
Xingxian Gu, Vijayalaxmi Gupta, Yan Yang, Jin-Yi Zhu, Erick J Carlson, Carolyn N Paulson, Joseph S Tash, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Structure-Activity Studies of N-Butyl-1-deoxynojirimycin (NB-DNJ) Analogues: Discovery of Potent and Selective Aminocyclopentitol Inhibitors of GBA1 and GBA2. ChemMedChem 12 (23) (2017)