Nicholas M Levinson (N M Levinson)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 24

Top Venues

eLife

Biochemical Society transactions

Journal of medicinal chemistry

bioRxiv : the preprint server for biology

University of Minnesota

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Minnesota Sep 08 2014

United States

Assistant Professor :: Pharmacology

Publications

Zachary D Baker, Damien M Rasmussen, Nicholas M Levinson
Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER. Biochemical Society transactions 52 (3) (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Zachary D Baker, Damien M Rasmussen, Nicholas M Levinson
Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER. Biochemical Society transactions 52 (3) (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Zachary D Baker, Damien M Rasmussen, Nicholas M Levinson
Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER. Biochemical Society transactions 52 (3) (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Zachary D Baker, Damien M Rasmussen, Nicholas M Levinson
Exploring the conformational landscapes of protein kinases: perspectives from FRET and DEER. Biochemical Society transactions (2024)
Damien M Rasmussen, Manny M Semonis, Joseph T Greene, Joseph M Muretta, Andrew R Thompson, Silvia Toledo Ramos, David Dt Thomas, William C K Pomerantz, Tanya S Freedman, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF by type II inhibitors. eLife 13 (2024)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry 66 (3) (2023)
Erik B Faber, Luxin Sun, Jian Tang, Emily R Roberts, Sornakala Ganeshkumar, Nan Wang, Damien M Rasmussen, Abir Majumdar, Laura E Hirsch, Kristen John, An Yang, Hira Khalid, Jon E Hawkinson, Nicholas M Levinson, Vargheese M Chennthukuzhi, Daniel A Harki, Ernst K Schonbrunn, Gunda I Georg
Development of allosteric and selective CDK2 inhibitors for contraception with negative cooperativity to cyclin binding. Nature communications 14 (1) (2023)
Damien M Rasmussen, Manny M Semonis, Joseph M Muretta, Andrew R Thompson, David Dt Thomas, William C K Pomerantz, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF. bioRxiv : the preprint server for biology (2023)
Damien M Rasmussen, Manny M Semonis, Joseph M Muretta, Andrew R Thompson, David Dt Thomas, William C K Pomerantz, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF. bioRxiv : the preprint server for biology (2023)
Damien M Rasmussen, Manny M Semonis, Joseph M Muretta, Andrew R Thompson, David Dt Thomas, William C K Pomerantz, Nicholas M Levinson
Allosteric coupling asymmetry mediates paradoxical activation of BRAF. bioRxiv : the preprint server for biology (2023)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry 66 (3) (2023)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry 66 (3) (2023)
Erik B Faber, Nan Wang, Kristen John, Luxin Sun, Henry L Wong, David Burban, Rawle Francis, Defeng Tian, Kwon H Hong, An Yang, Liming Wang, Mazen Elsaid, Hira Khalid, Nicholas M Levinson, Ernst K Schonbrunn, Jon E Hawkinson, Gunda I Georg
Screening through Lead Optimization of High Affinity, Allosteric Cyclin-Dependent Kinase 2 (CDK2) Inhibitors as Male Contraceptives That Reduce Sperm Counts in Mice. Journal of medicinal chemistry (2023)
N Tavernier, Y Thomas, S Vigneron, Pierre Maisonneuve, S Orlicky, P Mader, S G Regmi, L Van Hove, Nicholas M Levinson, G Gasmi-Seabrook, N Joly, M Poteau, G Velez-Aguilera, O Gavet, Anna Castro, Mary Dasso, T Lorca, Frank Sicheri, Lionel Pintard
Bora phosphorylation substitutes in trans for T-loop phosphorylation in Aurora A to promote mitotic entry. Nature communications 12 (1) (2021)
Abir Majumdar, David J Burban, Joseph M Muretta, Andrew R Thompson, Tiffany A Engel, Damien M Rasmussen, Manu V Subrahmanian, Gianluigi Veglia, David Dt Thomas, Nicholas M Levinson
Allostery governs Cdk2 activation and differential recognition of CDK inhibitors. Nature chemical biology 17 (4) (2021)
Erik B Faber, Defeng Tian, David Burban, Nicholas M Levinson, Jon E Hawkinson, Gunda I Georg
Cooperativity Between Orthosteric Inhibitors and Allosteric Inhibitor 8-Anilino-1-Naphthalene Sulfonic Acid (ANS) in Cyclin-Dependent Kinase 2. ACS chemical biology 15 (7) (2020)
Aaron B Edmund, Timothy F Walseth, Nicholas M Levinson, Lincoln R Potter
The pseudokinase domains of guanylyl cyclase-A and -B allosterically increase the affinity of their catalytic domains for substrate. Science signaling 12 (566) (2019)
Eric W Lake, Joseph M Muretta, Andrew R Thompson, Damien M Rasmussen, Abir Majumdar, Erik B Faber, Emily F Ruff, David D Thomas, Nicholas M Levinson
Quantitative conformational profiling of kinase inhibitors reveals origins of selectivity for Aurora kinase activation states. Proceedings of the National Academy of Sciences of the United States of America 115 (51) (2018)
Emily F Ruff, Joseph M Muretta, Andrew R Thompson, Eric W Lake, Soreen Cyphers, Steven K Albanese, Sonya M Hanson, Julie M Behr, David D Thomas, John D Chodera, Nicholas M Levinson
A dynamic mechanism for allosteric activation of Aurora kinase A by activation loop phosphorylation. eLife 7 (2018)

Nicholas M Levinson.css-eqlu8i{font-size:small;padding-left:4px;} (N M Levinson)

Publication Activity (10 Years)

Top Topics

Top Venues

Nicholas M Levinson (N M Levinson)