Jonathan C Kagan

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 58

Top Topics

Top Venues

Science immunology

Nature microbiology

Nature communications

This page only lists publications with an associated author ORCID identifier.

Publications

Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature 630 (8016) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature 630 (8016) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature 631 (8021) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature 631 (8021) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature 630 (8016) (2024)
Stephanie A Ragland, Jonathan C Kagan
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses. Science immunology 9 (96) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature 631 (8021) (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Stephanie A Ragland, Jonathan C Kagan
Waking the sleeping giant: Single-stranded DNA binds Schlafen 11 to initiate innate immune responses. Science immunology 9 (96) (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature 630 (8016) (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature 630 (8016) (2024)
Hannah Brown Harding, Geneva N Kwaku, Christopher M Reardon, Nida S Khan, Daniel Zamith-Miranda, Robert Zarnowski, Jenny M Tam, Collins K Bohaen, Lauren Richey, Kenta Mosallanejad, Arianne J Crossen, Jennifer L Reedy, Rebecca A Ward, Diego A Vargas-Blanco, Kyle J Basham, Roby P Bhattacharyya, Jeniel E Nett, Michael K Mansour, Frank L van de Veerdonk, Vinod Kumar, Jonathan C Kagan, David R Andes, Joshua Daniel Nosanchuk, Jatin M Vyas
Candida albicans extracellular vesicles trigger type I IFN signalling via cGAS and STING. Nature microbiology 9 (1) (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature (2024)
Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P Gygi, Hao Wu, Jonathan C Kagan
Publisher Correction: Structural insights into cytokine cleavage by inflammatory caspase-4. Nature (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Gang Du, Liam Brendan Healy, Liron David, Caitlin Walker, Tarick J El-Baba, Corinne A Lutomski, Byoungsook Goh, Bo-Wen Gu, Xiong Pi, Pascal Devant, Pietro Fontana, Ying Dong, Xiyu Ma, Rui Miao, Arumugam Balasubramanian, Robbins Puthenveetil, Anirban Banerjee, Hongbo R Luo, Jonathan C Kagan, Sungwhan F Oh, Carol V Robinson, Judy Lieberman, Hao Wu
ROS-dependent S-palmitoylation activates cleaved and intact gasdermin D. Nature 630 (8016) (2024)
Jonathan C Kagan
Innate immunity decreases pathogen diversity during infection. Proceedings of the National Academy of Sciences of the United States of America 120 (40) (2023)
Kenta Mosallanejad, Stephanie N Kennedy, Kristin M Bahleda, Kailey M Slavik, Wen Zhou, Apurva A Govande, Dustin C Hancks, Philip J Kranzusch, Jonathan C Kagan
Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases. Science immunology 8 (79) (2023)
Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P Gygi, Hao Wu, Jonathan C Kagan
Structural insights into cytokine cleavage by inflammatory caspase-4. Nature (2023)
Pascal Devant, Jonathan C Kagan
Molecular mechanisms of gasdermin D pore-forming activity. Nature immunology (2023)
Kenta Mosallanejad, Stephanie N Kennedy, Kristin M Bahleda, Kailey M Slavik, Wen Zhou, Apurva A Govande, Dustin C Hancks, Philip J Kranzusch, Jonathan C Kagan
Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases. Science immunology 8 (79) (2023)
Chao-Yu Wang, Ruoshi Zhang, Jia He, Lvshan Yu, Xinyan Li, Junxia Zhang, Sai Li, Conggang Zhang, Jonathan C Kagan, Jeffrey M Karp, Rui Kuai
Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity. Nature communications 14 (1) (2023)
Jonathan C Kagan
Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation. Nature immunology 24 (1) (2023)
Jonathan C Kagan
Excess lipids on endosomes dictates NLRP3 localization and inflammasome activation. Nature immunology 24 (1) (2023)
Dania Zhivaki, Emily A Gosselin, Debrup Sengupta, Holly Concepcion, Chisom Arinze, Jonathan Chow, Anastasia Nikiforov, Veronica Komoroski, Carolyn MacFarlane, Caitlin Sullivan, Jonathan C Kagan
mRNAs encoding self-DNA reactive cGAS enhance the immunogenicity of lipid nanoparticle vaccines. mBio (2023)
Chao-Yu Wang, Ruoshi Zhang, Jia He, Lvshan Yu, Xinyan Li, Junxia Zhang, Sai Li, Conggang Zhang, Jonathan C Kagan, Jeffrey M Karp, Rui Kuai
Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity. Nature communications 14 (1) (2023)
Chao-Yu Wang, Ruoshi Zhang, Jia He, Lvshan Yu, Xinyan Li, Junxia Zhang, Sai Li, Conggang Zhang, Jonathan C Kagan, Jeffrey M Karp, Rui Kuai
Ultrasound-responsive low-dose doxorubicin liposomes trigger mitochondrial DNA release and activate cGAS-STING-mediated antitumour immunity. Nature communications 14 (1) (2023)
Kenta Mosallanejad, Stephanie N Kennedy, Kristin M Bahleda, Kailey M Slavik, Wen Zhou, Apurva A Govande, Dustin C Hancks, Philip J Kranzusch, Jonathan C Kagan
Species-specific self-DNA detection mechanisms by mammalian cyclic GMP-AMP synthases. Science immunology 8 (79) (2023)
Jazlyn P Borges, Ragnhild S R Sætra, Allen Volchuk, Marit Bugge, Pascal Devant, Bjørnar Sporsheim, Bridget R Kilburn, Charles L Evavold, Jonathan C Kagan, Neil M Goldenberg, Trude Helen Flo, Benjamin Ethan Steinberg
Glycine inhibits NINJ1 membrane clustering to suppress plasma membrane rupture in cell death. eLife 11 (2022)
Anna E Gauthier, Randi D Rotjan, Jonathan C Kagan
Lipopolysaccharide detection by the innate immune system may be an uncommon defence strategy used in nature. Open biology 12 (10) (2022)
Anna E Gauthier, Courtney E Chandler, Valentina Poli, Francesca M Gardner, Aranteiti Tekiau, Richard Smith, Kevin S Bonham, Erik E Cordes, Timothy M Shank, Ivan Zanoni, David R Goodlett, Steven J Biller, Robert K Ernst, Randi D Rotjan, Jonathan C Kagan
Deep-sea microbes as tools to refine the rules of innate immune pattern recognition. Science immunology 6 (57) (2022)
Fabian A Fischer, Linda F M Mies, Sohaib Nizami, Eirini Pantazi, Sara Danielli, Benjamin Demarco, Michael Ohlmeyer, Michelle Sue Jann Lee, Cevayir Coban, Jonathan C Kagan, Elena Di Daniel, Jelena S Bezbradica
TBK1 and IKKε act like an OFF switch to limit NLRP3 inflammasome pathway activation. Proceedings of the National Academy of Sciences of the United States of America 118 (38) (2021)
Stephanie A Ragland, Jonathan C Kagan
Cytosolic detection of phagosomal bacteria-Mechanisms underlying PAMP exodus from the phagosome into the cytosol. Molecular microbiology (2021)
Dania Zhivaki, Jonathan C Kagan
Innate immune detection of lipid oxidation as a threat assessment strategy. Nature reviews. Immunology (2021)
George Maiti, Jihane Frikeche, Carly Yuen-Man Lam, Asim Biswas, Vishal Shinde, Marie I Samanovic, Jonathan C Kagan, Mark J Mulligan, Shukti Chakravarti
Matrix lumican endocytosed by immune cells controls receptor ligand trafficking to promote TLR4 and restrict TLR9 in sepsis. Proceedings of the National Academy of Sciences of the United States of America 118 (27) (2021)
Judy Lieberman, Hao Wu, Jonathan C Kagan
Gasdermin D activity in inflammation and host defense. Science immunology 4 (39) (2020)
Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, Arthur V Hauenstein, Giuseppe Di Caprio, Wesley Skillern, Qiufang Deng, Pontus Orning, Hasan B Alam, Zoltan Maliga, Humayun Sharif, Jun Jacob Hu, Charles L Evavold, Jonathan C Kagan, Florian Ingo Schmidt, Katherine A Fitzgerald, Tomas Kirchhausen, Yongqing Li, Hao Wu
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science (New York, N.Y.) 369 (6510) (2020)
Katherine C Barnett, Jonathan C Kagan
Lipids that directly regulate innate immune signal transduction. Innate immunity 26 (1) (2019)