Florian Ingo Schmidt (Florian I Schmidt)

Scopus Author ID Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 32

Top Venues

Nature

Science (New York, N.Y.)

Nature communications

The Journal of experimental medicine

Rheinische Friedrich Wilhelms Universität Bonn

TU München (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Rheinische Friedrich Wilhelms Universität Bonn Feb 01 2017

Germany

Emmy Noether group leader :: Institute of Innate Immunity

Children's Hospital Boston Dec 01 2016 - Jan 31 2017

United States

Postdoctoral Associate :: Program in Cellular and Molecular Medicine

Whitehead Institute for Biomedical Research Aug 01 2013 - Nov 30 2016

United States

Postdoctoral fellow

ETH Zurich Nov 01 2007 - May 31 2013

Switzerland

PhD student / postdoctoral fellow :: Institute of Biochemistry

Education History

TU München Oct 01 2005 - Sep 30 2007

Germany

MSC :: Chemistry

TU München Oct 01 2002 - Sep 30 2005

Germany

BSC :: Chemistry

Publications

Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 629 (8013) (2024)
Yiqi Huang, Valter Bergant, Vincent Grass, Quirin Emslander, M Sabri Hamad, Philipp Hubel, Julia Mergner, Antonio Piras, Karsten Krey, Alexander Henrici, Rupert Öllinger, Yonas M Tesfamariam, Ilaria Dalla Rosa, Till Bunse, Gerd Sutter, Gregor Ebert, Florian Ingo Schmidt, Michael Way, Roland Rad, Andrew G Bowie, Ulrike Protzer, Andreas Pichlmair
Multi-omics characterization of the monkeypox virus infection. Nature communications 15 (1) (2024)
Yiqi Huang, Valter Bergant, Vincent Grass, Quirin Emslander, M Sabri Hamad, Philipp Hubel, Julia Mergner, Antonio Piras, Karsten Krey, Alexander Henrici, Rupert Öllinger, Yonas M Tesfamariam, Ilaria Dalla Rosa, Till Bunse, Gerd Sutter, Gregor Ebert, Florian Ingo Schmidt, Michael Way, Roland Rad, Andrew G Bowie, Ulrike Protzer, Andreas Pichlmair
Multi-omics characterization of the monkeypox virus infection. Nature communications 15 (1) (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature (2024)
Yiqi Huang, Valter Bergant, Vincent Grass, Quirin Emslander, M Sabri Hamad, Philipp Hubel, Julia Mergner, Antonio Piras, Karsten Krey, Alexander Henrici, Rupert Öllinger, Yonas M Tesfamariam, Ilaria Dalla Rosa, Till Bunse, Gerd Sutter, Gregor Ebert, Florian Ingo Schmidt, Michael Way, Roland Rad, Andrew G Bowie, Ulrike Protzer, Andreas Pichlmair
Multi-omics characterization of the monkeypox virus infection. Nature communications 15 (1) (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 629 (8013) (2024)
Chao Wei, Wei Jiang, Ruiyu Wang, Haoyu Zhong, Huabin He, Xinwei Gao, Shilin Zhong, Fengting Yu, Qingchun Guo, Li Zhang, Lisa D J Schiffelers, Bin Zhou, Martin Trepel, Florian Ingo Schmidt, Minmin Luo, Feng Shao
Brain endothelial GSDMD activation mediates inflammatory BBB breakdown. Nature 629 (8013) (2024)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Anja Kopp, Gregor Hagelueken, Isabell Jamitzky, Jonas Moecking, Lisa D J Schiffelers, Florian Ingo Schmidt, Matthias Geyer
Pyroptosis inhibiting nanobodies block Gasdermin D pore formation. Nature communications 14 (1) (2023)
Kim Samirah Robinson, Gee Ann Toh, Muhammad Jasrie Firdaus, Khek-Chian Tham, Pritisha Rozario, Chrissie Kaishi Lim, Ying Xiu Toh, Zhi Heng Lau, Sophie Charlotte Binder, Jacob Mayer, Carine Bonnard, Florian Ingo Schmidt, John Edmund Armourer Common, Franklin Lei Zhong
Diphtheria toxin activates ribotoxic stress and NLRP1 inflammasome-driven pyroptosis. The Journal of experimental medicine 220 (10) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Jonas D Albarnaz, Joanne Kite, Marisa Oliveira, Hanqi Li, Ying Di, Maria H Christensen, Joao A Paulo, Robin Antrobus, Steven P Gygi, Florian Ingo Schmidt, Edward L Huttlin, Geoffrey L Smith, Michael P Weekes
Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection. Nature communications 14 (1) (2023)
Tomasz Próchnicki, Matilde B Vasconcelos, Kim S Robinson, Matthew S J Mangan, Dennis M De Graaf, Kateryna Shkarina, Marta Lovotti, Lena Standke, Romina Kaiser, Rainer Stahl, Fraser G Duthie, Maximilian Rothe, Kateryna Antonova, Lea-Marie Jenster, Zhi Heng Lau, Sarah Rösing, Nora Mirza, Clarissa Gottschild, Dagmar Wachten, Claudia Günther, Thomas A Kufer, Florian Ingo Schmidt, Franklin Lei Zhong, Eicke Latz
Mitochondrial damage activates the NLRP10 inflammasome. Nature immunology (2023)
Fatima Martin-Sanchez, Vincent Compan, Alejandro Peñín-Franch, Ana Tapia-Abellán, Ana I Gómez, María C Baños-Gregori, Florian Ingo Schmidt, Pablo Pelegrin
ASC oligomer favors caspase-1CARD domain recruitment after intracellular potassium efflux. The Journal of cell biology 222 (8) (2023)
Yuta Tsukamoto, Takahiro Hiono, Shintaro Yamada, Keita Matsuno, Aileen Faist, Tobias Claff, Jianyu Hou, Vigneshwaran Namasivayam, Anja Vom Hemdt, Satoko Sugimoto, Jin Ying Ng, Maria H Christensen, Yonas M Tesfamariam, Steven Wolter, Stefan Juranek, Thomas Zillinger, Stefan Bauer, Takatsugu Hirokawa, Florian Ingo Schmidt, Georg Kochs, Masayuki Shimojima, Yi-Shuian Huang, Andreas Pichlmair, Beate Mareike Kümmerer, Yoshihiro Sakoda, Martin Schlee, Linda Brunotte, Christa Elisabeth Müller, Manabu Igarashi, Hiroki Kato
Inhibition of cellular RNA methyltransferase abrogates influenza virus capping and replication. Science (New York, N.Y.) 379 (6632) (2023)
Lea-Marie Jenster, Karl-Elmar Lange, Sabine Normann, Anja Vom Hemdt, Jennifer Deborah Wuerth, Lisa D J Schiffelers, Yonas M Tesfamariam, Florian N Gohr, Laura Klein, Ines H Kaltheuner, Stefan Ebner, Dorothee Johanna Lapp, Jacob Mayer, Jonas Moecking, Hidde L Ploegh, Eicke Latz, Rüdiger Klein, Matthias Geyer, Beate Mareike Kümmerer, Florian Ingo Schmidt
P38 kinases mediate NLRP1 inflammasome activation after ribotoxic stress response and virus infection. The Journal of experimental medicine 220 (1) (2022)
Damien Bertheloot, Carlos Ws Wanderley, Ayda H Schneider, Lisa D J Schiffelers, Jennifer Deborah Wuerth, Jan M P Tödtmann, Salie Maasewerd, Ibrahim Hawwari, Fraser Duthie, Cornelia Rohland, Lucas S Ribeiro, Lea-Marie Jenster, Nathalia Rosero, Yonas M Tesfamariam, Fernando Q Cunha, Florian Ingo Schmidt, Bernardo Simoes Franklin
Nanobodies dismantle post-pyroptotic ASC specks and counteract inflammation in vivo. EMBO molecular medicine 14 (6) (2022)
Matthew S J Mangan, Friederike Gorki, Karoline Krause, Alexander Heinz, Anne Pankow, Thomas Ebert, Dieter Jahn, Karsten Hiller, Veit Hornung, Marcus Maurer, Florian Ingo Schmidt, Ralf Gerhard, Eicke Latz
Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever. PLoS biology 20 (11) (2022)
Paul-Albert Koenig, Hrishikesh Das, Hejun Liu, Beate M Kümmerer, Florian N Gohr, Lea-Marie Jenster, Lisa D J Schiffelers, Yonas M Tesfamariam, Miki Uchima, Jennifer Deborah Wuerth, Karl Gatterdam, Natalia Ruetalo, Maria H Christensen, Caroline I Fandrey, Sabine Normann, Jan M P Tödtmann, Steffen Pritzl, Leo Hanke, Jannik Boos, Meng Yuan, Xueyong Zhu, Jonathan L Schmid-Burgk, Hiroki Kato, Michael Schindler, Ian A Wilson, Matthias Geyer, Kerstin U Ludwig, B Martin Hällberg, Nicholas C Wu, Florian Ingo Schmidt
Structure-guided multivalent nanobodies block SARS-CoV-2 infection and suppress mutational escape. Science (New York, N.Y.) 371 (6530) (2021)
Paul-Albert Koenig, Florian Ingo Schmidt
Spike D614G - A Candidate Vaccine Antigen Against Covid-19. The New England journal of medicine 384 (24) (2021)
Florian Ingo Schmidt, Eicke Latz
Jack of all trades inhibits inflammation (in sober people). Nature immunology 21 (7) (2020)
Jan Niklas Hansen, Fabian Kaiser, Christina Klausen, Birthe Stüven, Raymond Chong, Wolfgang Bönigk, David U Mick, Andreas Möglich, Nathalie Jurisch-Yaksi, Florian Ingo Schmidt, Dagmar Wachten
Nanobody-directed targeting of optogenetic tools to study signaling in the primary cilium. eLife 9 (2020)
Matteo Bosso, Caterina Prelli Bozzo, Dominik Hotter, Meta Volcic, Christina M Stürzel, Annika Rammelt, Yi Ni, Stephan Urban, Miriam Becker, Mario Schelhaas, Sabine Wittmann, Maria H Christensen, Florian Ingo Schmidt, Thomas Gramberg, Konstantin Maria Johannes Sparrer, Daniel Sauter, Frank Kirchhoff
Nuclear PYHIN proteins target the host transcription factor Sp1 thereby restricting HIV-1 in human macrophages and CD4+ T cells. PLoS pathogens 16 (8) (2020)
Venkat Giri Magupalli, Roberto Negro, Yuzi Tian, Arthur V Hauenstein, Giuseppe Di Caprio, Wesley Skillern, Qiufang Deng, Pontus Orning, Hasan B Alam, Zoltan Maliga, Humayun Sharif, Jun Jacob Hu, Charles L Evavold, Jonathan C Kagan, Florian Ingo Schmidt, Katherine A Fitzgerald, Tomas Kirchhausen, Yongqing Li, Hao Wu
HDAC6 mediates an aggresome-like mechanism for NLRP3 and pyrin inflammasome activation. Science (New York, N.Y.) 369 (6510) (2020)
Florian Ingo Schmidt
From atoms to physiology: what it takes to really understand inflammasomes. The Journal of physiology 597 (22) (2019)
Bernardo Simoes Franklin, Eicke Latz, Florian Ingo Schmidt
The intra- and extracellular functions of ASC specks. Immunological reviews 281 (1) (2018)
Leo Hanke, Florian Ingo Schmidt, Kevin E Knockenhauer, Benjamin Morin, Sean Pj Whelan, Thomas U Schwartz, Hidde L Ploegh
Vesicular stomatitis virus N protein-specific single-domain antibody fragments inhibit replication. EMBO reports 18 (6) (2017)
Florian Ingo Schmidt, Leo Hanke, Benjamin Morin, Rebeccah Brewer, Vesna Brusic, Sean P J Whelan, Hidde L Ploegh
Phenotypic lentivirus screens to identify functional single domain antibodies. Nature microbiology 1 (8) (2016)
Alvin Lu, Yang Li, Florian Ingo Schmidt, Qian Yin, Shuobing Chen, Tian-Min Fu, Alexander B Tong, Hidde L Ploegh, Youdong Mao, Hao Wu
Molecular basis of caspase-1 polymerization and its inhibition by a new capping mechanism. Nature structural & molecular biology 23 (5) (2016)

Florian Ingo Schmidt.css-eqlu8i{font-size:small;padding-left:4px;} (Florian I Schmidt)

Publication Activity (10 Years)

Top Topics

Top Venues

Florian Ingo Schmidt (Florian I Schmidt)