Steven P Gygi (Steve P Gygi, Steven Gygi)

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 149

Top Venues

Journal of proteome research

Nature communications

eLife

Nature

This page only lists publications with an associated author ORCID identifier.

Publications

Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology (2024)
Rafael A Talavara, Beth E Prichard, Robert A Sommer, Ricardo M Leitao, Christopher J Sarabia, Semin Hazir, Joao A Paulo, Steven P Gygi, Douglas R Kellogg
Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast. The Journal of cell biology 223 (8) (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology 20 (8) (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife 12 (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
José Pedro Castro, Anastasia V Shindyapina, Alessandro Barbieri, Albert K Ying, Olga S Strelkova, Joao A Paulo, Alexander Tyshkovskiy, Rico Meinl, Csaba Kerepesi, Anna P Petrashen, Marco Mariotti, Margarita V Meer, Yan Hu, Alexander Karamyshev, Grigoriy Losyev, Mafalda Galhardo, Elsa Logarinho, Artur A Indzhykulian, Steven P Gygi, John M Sedivy, John P Manis, Vadim N Gladyshev
Age-associated clonal B cells drive B cell lymphoma in mice. Nature aging (2024)
Benjamin E Gewurz, Rui Guo, Matthew Y Lim, Hardik Shah, Joao A Paulo, Yuchen Zhang, Haopeng Yang, Liang Wei Wang, Daniel Strebinger, Nicolas Smith, Meng Li, Merrin Leong, Michael Lutchenkov, Jin-Hua Liang, Zhixuan Li, Yin Wang, Rishi Puri, Ari Melnick, Michael Green, John M Asara, Adonia Papathanassiu, Steven P Gygi, Vamsi K Mootha
Multi-omic Analysis of Human B-cell Activation Reveals a Key Lysosomal BCAT1 Role in mTOR Hyperactivation by B-cell receptor and TLR9. Research square (2024)
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife 12 (2024)
Rafael A Talavara, Beth E Prichard, Robert A Sommer, Ricardo M Leitao, Christopher J Sarabia, Semin Hazir, Joao A Paulo, Steven P Gygi, Douglas R Kellogg
Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast. The Journal of cell biology 223 (8) (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife 12 (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology (2024)
Tiasha A Shafiq, Juntao Yu, Wenzhi Feng, Yi-Zhe Zhang, Haining Zhou, Joao A Paulo, Steven P Gygi, Danesh Moazed
Genomic context- and H2AK119 ubiquitination-dependent inheritance of human Polycomb silencing. Science advances 10 (19) (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature 631 (8021) (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing. bioRxiv : the preprint server for biology (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Weicheng Li, Enrique M Garcia-Rivera, Dylan C Mitchell, Joel M Chick, Micah Maetani, John M Knapp, Geoffrey M Matthews, Ryosuke Shirasaki, Ricardo Matos de Simoes, Vasanthi S Viswanathan, John L Pulice, Matthew G Rees, Jennifer A Roth, Steven P Gygi, Constantine S Mitsiades, Cigall Kadoch, Stuart L Schreiber, Jonathan M L Ostrem
Highly specific intracellular ubiquitination of a small molecule. bioRxiv : the preprint server for biology (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature 631 (8021) (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing. bioRxiv : the preprint server for biology (2024)
Tiasha A Shafiq, Juntao Yu, Wenzhi Feng, Yi-Zhe Zhang, Haining Zhou, Joao A Paulo, Steven P Gygi, Danesh Moazed
Genomic context- and H2AK119 ubiquitination-dependent inheritance of human Polycomb silencing. Science advances 10 (19) (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics with Sample Multiplexing. Journal of proteome research 23 (5) (2024)
Ka Yang, Joao A Paulo, Steven P Gygi, Qing Yu
Enhanced Sample Multiplexing-Based Targeted Proteomics with Intelligent Data Acquisition. Journal of the American Society for Mass Spectrometry (2024)
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife 12 (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing. bioRxiv : the preprint server for biology (2024)
Jonathan G Van Vranken, Jiaming Li, Julian Mintseris, Meagan Gadzuk-Shea, Steven P Gygi, Devin K Schweppe
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays. bioRxiv : the preprint server for biology (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdoǧan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology (2024)
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife 12 (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature 631 (8021) (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
José Pedro Castro, Anastasia V Shindyapina, Alessandro Barbieri, Albert K Ying, Olga S Strelkova, Joao A Paulo, Alexander Tyshkovskiy, Rico Meinl, Csaba Kerepesi, Anna P Petrashen, Marco Mariotti, Margarita V Meer, Yan Hu, Alexander Karamyshev, Grigoriy Losyev, Mafalda Galhardo, Elsa Logarinho, Artur A Indzhykulian, Steven P Gygi, John M Sedivy, John P Manis, Vadim N Gladyshev
Age-associated clonal B cells drive B cell lymphoma in mice. Nature aging (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics with Sample Multiplexing. Journal of proteome research (2024)
Rafael A Talavara, Beth E Prichard, Robert A Sommer, Ricardo M Leitao, Christopher J Sarabia, Semin Hazir, Joao A Paulo, Steven P Gygi, Douglas R Kellogg
Cell growth and nutrient availability control the mitotic exit signaling network in budding yeast. The Journal of cell biology 223 (8) (2024)
Benjamin E Gewurz, Rui Guo, Matthew Y Lim, Hardik Shah, Joao A Paulo, Yuchen Zhang, Haopeng Yang, Liang Wei Wang, Daniel Strebinger, Nicolas Smith, Meng Li, Merrin Leong, Michael Lutchenkov, Jin-Hua Liang, Zhixuan Li, Yin Wang, Rishi Puri, Ari Melnick, Michael Green, John M Asara, Adonia Papathanassiu, Steven P Gygi, Vamsi K Mootha
Multi-omic Analysis of Human B-cell Activation Reveals a Key Lysosomal BCAT1 Role in mTOR Hyperactivation by B-cell receptor and TLR9. Research square (2024)
Weicheng Li, Enrique M Garcia-Rivera, Dylan C Mitchell, Joel M Chick, Micah Maetani, John M Knapp, Geoffrey M Matthews, Ryosuke Shirasaki, Ricardo Matos de Simoes, Vasanthi S Viswanathan, John L Pulice, Matthew G Rees, Jennifer A Roth, Steven P Gygi, Constantine S Mitsiades, Cigall Kadoch, Stuart L Schreiber, Jonathan M L Ostrem
Highly specific intracellular ubiquitination of a small molecule. bioRxiv : the preprint server for biology (2024)
Wayne Mitchell, Ludger J E Goeminne, Alexander Tyshkovskiy, Sirui Zhang, Julie Y Chen, Joao A Paulo, Kerry A Pierce, Angelina H Choy, Clary B Clish, Steven P Gygi, Vadim N Gladyshev
Multi-omics characterization of partial chemical reprogramming reveals evidence of cell rejuvenation. eLife 12 (2024)
Jonathan G Van Vranken, Jiaming Li, Julian Mintseris, Meagan Gadzuk-Shea, Steven P Gygi, Devin K Schweppe
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays. bioRxiv : the preprint server for biology (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Benjamin E Gewurz, Rui Guo, Matthew Y Lim, Hardik Shah, Joao A Paulo, Yuchen Zhang, Haopeng Yang, Liang Wei Wang, Daniel Strebinger, Nicolas Smith, Meng Li, Merrin Leong, Michael Lutchenkov, Jin-Hua Liang, Zhixuan Li, Yin Wang, Rishi Puri, Ari Melnick, Michael Green, John M Asara, Adonia Papathanassiu, Steven P Gygi, Vamsi K Mootha
Multi-omic Analysis of Human B-cell Activation Reveals a Key Lysosomal BCAT1 Role in mTOR Hyperactivation by B-cell receptor and TLR9. Research square (2024)
Judith Frydman, Ching-Chieh Chou, Ryan Vest, Miguel A Prado, Joshua Wilson-Grady, Joao A Paulo, Yohei Shibuya, Patricia Moran Losada, Ting-Ting Lee, Jian Luo, Steven P Gygi, Jeffrey W Kelly, Daniel Finley, Marius Wernig, Tony Wyss-Coray
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes. Research square (2024)
Clarice Gareri, Conrad T Pfeiffer, Xue Jiang, Joao A Paulo, Steven P Gygi, Uyen Pham, Anand Chundi, Laura M Wingler, Dean P Staus, Tomasz Maciej Stepniewski, Jana Selent, Emilio Y Lucero, Alyssa Grogan, Sudarshan Rajagopal, Howard A Rockman
Phosphorylation patterns in the AT1R C-terminal tail specify distinct downstream signaling pathways. Science signaling 17 (849) (2024)
Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P Gygi, Hao Wu, Jonathan C Kagan
Publisher Correction: Structural insights into cytokine cleavage by inflammatory caspase-4. Nature (2024)
Jonathan G Van Vranken, Jiaming Li, Julian Mintseris, Meagan Gadzuk-Shea, Steven P Gygi, Devin K Schweppe
Large-scale characterization of drug mechanism of action using proteome-wide thermal shift assays. bioRxiv : the preprint server for biology (2024)
Tiasha A Shafiq, Juntao Yu, Wenzhi Feng, Yi-Zhe Zhang, Haining Zhou, Joao A Paulo, Steven P Gygi, Danesh Moazed
Genomic context- and H2AK119 ubiquitination-dependent inheritance of human Polycomb silencing. Science advances 10 (19) (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics with Sample Multiplexing. Journal of proteome research 23 (5) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics with Sample Multiplexing. Journal of proteome research (2024)
Daniel Fisch, Tian Zhang, He Sun, Weiyi Ma, Yunhao Tan, Steven P Gygi, Darren E Higgins, Jonathan C Kagan
Molecular definition of the endogenous Toll-like receptor signalling pathways. Nature (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing. bioRxiv : the preprint server for biology (2024)
Tiasha A Shafiq, Juntao Yu, Wenzhi Feng, Yi-Zhe Zhang, Haining Zhou, Joao A Paulo, Steven P Gygi, Danesh Moazed
Genomic context- and H2AK119 ubiquitination-dependent inheritance of human Polycomb silencing. Science advances 10 (19) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Judith Frydman, Ching-Chieh Chou, Ryan Vest, Miguel A Prado, Joshua Wilson-Grady, Joao A Paulo, Yohei Shibuya, Patricia Moran Losada, Ting-Ting Lee, Jian Luo, Steven P Gygi, Jeffrey W Kelly, Daniel Finley, Marius Wernig, Tony Wyss-Coray
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes. Research square (2024)
Matthew W McHenry, Peiwen Shi, Christina M Camara, Daniel T Cohen, T Justin Rettenmaier, Utsarga Adhikary, Micah A Gygi, Ka Yang, Steven P Gygi, Thomas E Wales, John R Engen, James A Wells, Loren D Walensky
Covalent inhibition of pro-apoptotic BAX. Nature chemical biology 20 (8) (2024)
Yeyun Ouyang, Mi-Young Jeong, Corey N Cunningham, Jordan A Berg, Ashish G Toshniwal, Casey E Hughes, Kristina Seiler, Jonathan G Van Vranken, Ahmad A Cluntun, Geanette Lam, Jacob M Winter, Emel Akdogan, Katja K Dove, Sara M Nowinski, Matthew West, Greg Odorizzi, Steven P Gygi, Cory D Dunn, Dennis R Winge, Jared Rutter
Phosphate starvation signaling increases mitochondrial membrane potential through respiration-independent mechanisms. eLife 13 (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics with Sample Multiplexing. Journal of proteome research 23 (5) (2024)
Ching-Chieh Chou, Ryan Vest, Miguel A Prado, Joshua Wilson-Grady, Joao A Paulo, Yohei Shibuya, Patricia Moran-Losada, Ting-Ting Lee, Jian Luo, Steven P Gygi, Jeffrey W Kelly, Daniel Finley, Marius Wernig, Tony Wyss-Coray, Judith Frydman
Human tNeurons reveal aging-linked proteostasis deficits driving Alzheimer's phenotypes. Research square (2024)
Steven R Shuken, Qing Yu, Steven P Gygi
Inserting Pre-Analytical Chromatographic Priming Runs Significantly Improves Targeted Pathway Proteomics With Sample Multiplexing. bioRxiv : the preprint server for biology (2024)
Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith A Simcox, Gary A Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature communications 14 (1) (2023)
Monica J Bohmer, Jinhua Wang, Eva S Istvan, Madeline R Luth, Jennifer E Collins, Edward L Huttlin, Lushun Wang, Nimisha Mittal, Mingfeng Hao, Nicholas P Kwiatkowski, Steven P Gygi, Ratna Chakrabarti, Xianming Deng, Daniel E Goldberg, Elizabeth A Winzeler, Nathanael S Gray, Debopam Chakrabarti
Human Polo-like Kinase Inhibitors as Antiplasmodials. ACS infectious diseases (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Kevin D Dong, Ernst W Schmid, Ryan D Bomgarden, Jae H Choi, Steven P Gygi, Qing Yu, Joao A Paulo
Adapting an Isobaric Tag-Labeled Yeast Peptide Standard to Develop Targeted Proteomics Assays. Journal of proteome research (2023)
Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith A Simcox, Gary A Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature communications 14 (1) (2023)
Weihai Liu, Yun Wang, Luiz H M Bozi, Patrick D Fischer, Mark P Jedrychowski, Haopeng Xiao, Tao Wu, Narek Darabedian, Xiadi He, Evanna L Mills, Nils Burger, Sanghee Shin, Anita Reddy, Hans-Georg Sprenger, Nhien Tran, Sally Winther, Stephen M Hinshaw, Jingnan Shen, Hyuk-Soo Seo, Kijun Song, Andrew Z Xu, Luke Sebastian, Jean J Zhao, Sirano Dhe-Paganon, Jianwei Che, Steven P Gygi, Haribabu Arthanari, Edward T Chouchani
Lactate regulates cell cycle by remodeling the anaphase promoting complex. Nature (2023)
Alan T Yeo, Rushil Shah, Konstantinos Aliazis, Rinku Pal, Tuoye Xu, Piyan Zhang, Shruti Rawal, Christopher M Rose, Frederick S Varn, Vicky A Appleman, Joon Yoon, Hemant Varma, Steven P Gygi, Roel G W Verhaak, Vassiliki A Boussiotis, Alain Charest
Driver mutations dictate the immunological landscape and response to checkpoint immunotherapy of glioblastoma. Cancer immunology research (2023)
Pascal Devant, Ying Dong, Julian Mintseris, Weiyi Ma, Steven P Gygi, Hao Wu, Jonathan C Kagan
Structural insights into cytokine cleavage by inflammatory caspase-4. Nature (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Ning Wang, Yoko Shibata, Joao A Paulo, Steven P Gygi, Tom A Rapoport
A conserved membrane curvature-generating protein is crucial for autophagosome formation in fission yeast. Nature communications 14 (1) (2023)
Tian Zhang, Xinyue Liu, Valentina Rossio, Shane L Dawson, Steven P Gygi, Joao A Paulo
Enhancing Proteome Coverage by Using Strong Anion-Exchange in Tandem with Basic-pH Reversed-Phase Chromatography for Sample Multiplexing-Based Proteomics. Journal of proteome research (2023)
Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith A Simcox, Gary A Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature communications 14 (1) (2023)
Ziqi Hu, Mingzhu Zhang, Jiankun Fan, Jiandong Hu, Guochao Lin, Shengwen Piao, Peng Liu, Jichao Liu, Songbin Fu, Wenjing Sun, Steven P Gygi, Jinwei Zhang, Chunshui Zhou
High-Level Secretion of Pregnancy Zone Protein Is a Novel Biomarker of DNA Damage-Induced Senescence and Promotes Spontaneous Senescence. Journal of proteome research (2023)
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph Stephan Clemen, Conrad C Weihl, John G Purdy, Steven P Gygi, Malavika Raman
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition. Nature communications 14 (1) (2023)
Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith A Simcox, Gary A Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature communications 14 (1) (2023)
Jonas D Albarnaz, Joanne Kite, Marisa Oliveira, Hanqi Li, Ying Di, Maria H Christensen, Joao A Paulo, Robin Antrobus, Steven P Gygi, Florian Ingo Schmidt, Edward L Huttlin, Geoffrey L Smith, Michael P Weekes
Quantitative proteomics defines mechanisms of antiviral defence and cell death during modified vaccinia Ankara infection. Nature communications 14 (1) (2023)
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph Stephan Clemen, Conrad C Weihl, John G Purdy, Steven P Gygi, Malavika Raman
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition. Nature communications 14 (1) (2023)
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph Stephan Clemen, Conrad C Weihl, John G Purdy, Steven P Gygi, Malavika Raman
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition. Nature communications 14 (1) (2023)
Dylan C Mitchell, Miljan Kuljanin, Jiaming Li, Jonathan G Van Vranken, Nathan Bulloch, Devin K Schweppe, Edward L Huttlin, Steven P Gygi
A proteome-wide atlas of drug mechanism of action. Nature biotechnology (2023)
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph Stephan Clemen, Conrad C Weihl, John G Purdy, Steven P Gygi, Malavika Raman
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition. Nature communications 14 (1) (2023)
Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith A Simcox, Gary A Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature communications 14 (1) (2023)
Jiaxin Liang, Tevis Vitale, Xixi Zhang, Thomas D Jackson, Deyang Yu, Mark Jedrychowski, Steven P Gygi, Hans R Widlund, Kai W Wucherpfennig, Pere Puigserver
Selective Mitochondrial Respiratory Complex I Subunit Deficiency Causes Tumor Immunogenicity. bioRxiv : the preprint server for biology (2023)
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph Stephan Clemen, Conrad C Weihl, John G Purdy, Steven P Gygi, Malavika Raman
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition. Nature communications 14 (1) (2023)
Jiaxin Liang, Deyang Yu, Chi Luo, Christopher Bennett, Mark Jedrychowski, Steven P Gygi, Hans R Widlund, Pere Puigserver
Epigenetic suppression of PGC1α (PPARGC1A) causes collateral sensitivity to HMGCR-inhibitors within BRAF-treatment resistant melanomas. Nature communications 14 (1) (2023)
Monica J Bohmer, Jinhua Wang, Eva S Istvan, Madeline R Luth, Jennifer E Collins, Edward L Huttlin, Lushun Wang, Nimisha Mittal, Mingfeng Hao, Nicholas P Kwiatkowski, Steven P Gygi, Ratna Chakrabarti, Xianming Deng, Daniel E Goldberg, Elizabeth A Winzeler, Nathanael S Gray, Debopam Chakrabarti
Human Polo-like Kinase Inhibitors as Antiplasmodials. ACS infectious diseases (2023)
Qing Yu, Xinyue Liu, Mark P Keller, Jose Navarrete-Perea, Tian Zhang, Sipei Fu, Laura P Vaites, Steven R Shuken, Ernst Schmid, Gregory R Keele, Jiaming Li, Edward L Huttlin, Edrees H Rashan, Judith A Simcox, Gary A Churchill, Devin K Schweppe, Alan D Attie, Joao A Paulo, Steven P Gygi
Sample multiplexing-based targeted pathway proteomics with real-time analytics reveals the impact of genetic variation on protein expression. Nature communications 14 (1) (2023)
Rakesh Ganji, Joao A Paulo, Yuecheng Xi, Ian Kline, Jiang Zhu, Christoph Stephan Clemen, Conrad C Weihl, John G Purdy, Steven P Gygi, Malavika Raman
The p97-UBXD8 complex regulates ER-Mitochondria contact sites by altering membrane lipid saturation and composition. Nature communications 14 (1) (2023)
Sarah C Erlandson, Shaun Rawson, James Osei-Owusu, Kelly P Brock, Xinyue Liu, Joao A Paulo, Julian Mintseris, Steven P Gygi, Debora S Marks, Xiaojing Cong, Andrew C Kruse
The relaxin receptor RXFP1 signals through a mechanism of autoinhibition. Nature chemical biology (2023)
Steven R Shuken, Graeme C McAlister, William D Barshop, Jesse D Canterbury, David Bergen, Jingjing Huang, Romain Huguet, João A Paulo, Vlad Zabrouskov, Steven P Gygi, Qing Yu
Deep Proteomic Compound Profiling with the Orbitrap Ascend Tribrid Mass Spectrometer Using Tandem Mass Tags and Real-Time Search. Analytical chemistry (2023)
Tian Zhang, Anne Fassl, Laura P Vaites, Sipei Fu, Piotr Sicinski, Joao A Paulo, Steven P Gygi
Interrogating Kinase-Substrate Relationships with Proximity Labeling and Phosphorylation Enrichment. Journal of proteome research 21 (2) (2022)
Helen A B Paterson, Sijia Yu, Natalia Artigas, Miguel A Prado, Nejc Haberman, Yi-Fang Wang, Andrew M Jobbins, Elena Pahita, Joao B Mokochinski, Zoe Hall, Maryse Guerin, Joao A Paulo, Soon Seng Ng, Francesc Villarroya, Sheikh Tamir Rashid, Wilfried Le Goff, Boris Lenhard, Inês Cebola, Daniel Finley, Steven P Gygi, Christopher R Sibley, Santiago Vernia
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice. Nature metabolism 4 (12) (2022)
Xinyue Liu, Jiaming Li, Steven P Gygi, Joao A Paulo
Profiling Yeast Deletion Strains Using Sample Multiplexing and Network-Based Analyses. Journal of proteome research 21 (6) (2022)

Steven P Gygi.css-eqlu8i{font-size:small;padding-left:4px;} (Steve P Gygi, Steven Gygi)

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Steven P Gygi (Steve P Gygi, Steven Gygi)