Wenyi Wei

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 78

Top Topics

Top Venues

Journal of the American Chemical Society

Nature communications

Science immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Xiaoming Dai, Peiqiang Yan, Wenyi Wei
Amino acid availability governs mTOR ubiquitination. Cell research 34 (5) (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Jing Liu, Xiaoping Hu, Kaixiu Luo, Yan Xiong, Li Chen, Zhen Wang, Hiroyuki Inuzuka, Chao Qian, Xufen Yu, Ling Xie, Adil Muneer, Dingpeng Zhang, Joao A Paulo, Xian Chen, Jian Jin, Wenyi Wei
USP7-Based Deubiquitinase-Targeting Chimeras Stabilize AMPK. Journal of the American Chemical Society (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society 146 (11) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society 146 (11) (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society 146 (11) (2024)
Xiaoming Dai, Peiqiang Yan, Wenyi Wei
Amino acid availability governs mTOR ubiquitination. Cell research 34 (5) (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society 146 (11) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Arumugam Balasubramanian, Alan Y Hsu, Laxman Ghimire, Muhammad Tahir, Pascal Devant, Pietro Fontana, Gang Du, Xing Liu, Fabin Dang, Hiroto Kambara, Xuemei Xie, Fei Liu, Tomoya Hasegawa, Rong Xu, Hongbo Yu, Mei Chen, Steven Kolakowski, Sunia A Trauger, Martin Røssel Larsen, Wenyi Wei, Hao Wu, Jonathan C Kagan, Judy Lieberman, Hongbo R Luo
The palmitoylation of gasdermin D directs its membrane translocation and pore formation during pyroptosis. Science immunology 9 (94) (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society 146 (11) (2024)
Xiaoming Dai, Peiqiang Yan, Wenyi Wei
Amino acid availability governs mTOR ubiquitination. Cell research 34 (5) (2024)
Xiaoming Dai, Peiqiang Yan, Wenyi Wei
Amino acid availability governs mTOR ubiquitination. Cell research 34 (5) (2024)
Zhen Wang, Dingpeng Zhang, Xing Qiu, Hiroyuki Inuzuka, Yan Xiong, Jing Liu, Li Chen, He Chen, Ling Xie, H Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Structurally Specific Z-DNA Proteolysis Targeting Chimera Enables Targeted Degradation of Adenosine Deaminase Acting on RNA 1. Journal of the American Chemical Society 146 (11) (2024)
Xiaoming Dai, Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo, Peiqiang Yan, Fangtao Chi, Tao Zhang, Hiroyuki Inuzuka, John M Asara, Ping Wang, Jian-Ping Guo, Wenyi Wei
AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation. Nature metabolism 5 (2) (2023)
Xiaoming Dai, Peiqiang Yan, Wenyi Wei
Amino acid availability governs mTOR ubiquitination. Cell research (2023)
Xiaoming Dai, Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo, Peiqiang Yan, Fangtao Chi, Tao Zhang, Hiroyuki Inuzuka, John M Asara, Ping Wang, Jian-Ping Guo, Wenyi Wei
AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation. Nature metabolism 5 (2) (2023)
Zhen Wang, Jing Liu, He Chen, Xing Qiu, Ling Xie, Husnu Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. Journal of the American Chemical Society 145 (19) (2023)
Tao Zhang, Daichao Xu, Jianping Liu, Min Wang, Li-Juan Duan, Min Liu, Huyan Meng, Yuan Zhuang, Huibing Wang, Yingnan Wang, Mingming Lv, Zhengyi Zhang, Jia Hu, Linyu Shi, Rui Guo, Xingxing Xie, Hui Liu, Emily Erickson, Yaru Wang, Wenyu Yu, Fabin Dang, Dongxian Guan, Cong Jiang, Xiaoming Dai, Hiroyuki Inuzuka, Peiqiang Yan, Jingchao Wang, Mrigya Babuta, Gewei Lian, Zhenbo Tu, Ji Miao, Gyongyi Szabo, Guo-Hua Fong, Antoine E Karnoub, Yu-Ru Lee, Lifeng Pan, William G Kaelin, Junying Yuan, Wenyi Wei
Prolonged hypoxia alleviates prolyl hydroxylation-mediated suppression of RIPK1 to promote necroptosis and inflammation. Nature cell biology (2023)
Zhen Wang, Jing Liu, He Chen, Xing Qiu, Ling Xie, Husnu Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. Journal of the American Chemical Society 145 (19) (2023)
Xiaoming Dai, Peiqiang Yan, Wenyi Wei
Amino acid availability governs mTOR ubiquitination. Cell research (2023)
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C Erickson, Alissandra L Hillis, Christian C Dibble, John M Asara, Gyongyi Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J Shaw, Junying Yuan, Wenyi Wei
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.) 380 (6652) (2023)
Xiaoming Dai, Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo, Peiqiang Yan, Fangtao Chi, Tao Zhang, Hiroyuki Inuzuka, John M Asara, Ping Wang, Jian-Ping Guo, Wenyi Wei
AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation. Nature metabolism 5 (2) (2023)
Zhen Wang, Jing Liu, Xing Qiu, Dingpeng Zhang, Hiroyuki Inuzuka, Li Chen, He Chen, Ling Xie, Husnu Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Methylated Nucleotide-Based Proteolysis-Targeting Chimera Enables Targeted Degradation of Methyl-CpG-Binding Protein 2. Journal of the American Chemical Society (2023)
Zhen Wang, Jing Liu, He Chen, Xing Qiu, Ling Xie, Husnu Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. Journal of the American Chemical Society 145 (19) (2023)
Xiangling Xiao, Jie Shi, Chuan He, Xia Bu, Yishuang Sun, Minling Gao, Bolin Xiang, Wenjun Xiong, Panpan Dai, Qi Mao, Xixin Xing, Yingmeng Yao, Haisheng Yu, Gaoshan Xu, Siqi Li, Yan Ren, Baoxiang Chen, Congqing Jiang, Geng Meng, Yu-Ru Lee, Wenyi Wei, Gordon J Freeman, Conghua Xie, Jinfang Zhang
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy. Nature communications 14 (1) (2023)
Jing Liu, Xia Bu, Chen Chu, Xiaoming Dai, John M Asara, Piotr Sicinski, Gordon J Freeman, Wenyi Wei
PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity. Nature communications 14 (1) (2023)
Jing Liu, Xia Bu, Chen Chu, Xiaoming Dai, John M Asara, Piotr Sicinski, Gordon J Freeman, Wenyi Wei
PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity. Nature communications 14 (1) (2023)
Fabin Dang, Lei Bai, Jiazhen Dong, Xiaoping Hu, Jingchao Wang, Joao A Paulo, Yan Xiong, Xiaowei Liang, Yishuang Sun, Yuncai Chen, Ming Guo, Xin Wang, Zhixiang Huang, Hiroyuki Inuzuka, Li Chen, Chen Chu, Jianping Liu, Tao Zhang, Abdol-Hossein Rezaeian, Jing Liu, Husnu Ümit Kaniskan, Bo Zhong, Jinfang Zhang, Michael Letko, Jian Jin, Ke Lan, Wenyi Wei
USP2 inhibition prevents infection with ACE2-dependent coronaviruses in vitro and is protective against SARS-CoV-2 in mice. Science translational medicine 15 (725) (2023)
Zhen Wang, Jing Liu, He Chen, Xing Qiu, Ling Xie, Husnu Ümit Kaniskan, Xian Chen, Jian Jin, Wenyi Wei
Telomere Targeting Chimera Enables Targeted Destruction of Telomeric Repeat-Binding Factor Proteins. Journal of the American Chemical Society (2023)
Xiangling Xiao, Jie Shi, Chuan He, Xia Bu, Yishuang Sun, Minling Gao, Bolin Xiang, Wenjun Xiong, Panpan Dai, Qi Mao, Xixin Xing, Yingmeng Yao, Haisheng Yu, Gaoshan Xu, Siqi Li, Yan Ren, Baoxiang Chen, Congqing Jiang, Geng Meng, Yu-Ru Lee, Wenyi Wei, Gordon J Freeman, Conghua Xie, Jinfang Zhang
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy. Nature communications 14 (1) (2023)
Xiaoming Dai, Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo, Peiqiang Yan, Fangtao Chi, Tao Zhang, Hiroyuki Inuzuka, John M Asara, Ping Wang, Jian-Ping Guo, Wenyi Wei
AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation. Nature metabolism 5 (2) (2023)
Xiaoming Dai, Cong Jiang, Qiwei Jiang, Lan Fang, Haihong Yu, Jinhe Guo, Peiqiang Yan, Fangtao Chi, Tao Zhang, Hiroyuki Inuzuka, John M Asara, Ping Wang, Jian-Ping Guo, Wenyi Wei
AMPK-dependent phosphorylation of the GATOR2 component WDR24 suppresses glucose-mediated mTORC1 activation. Nature metabolism (2023)
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C Erickson, Alissandra L Hillis, Christian C Dibble, John M Asara, Gyongyi Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J Shaw, Junying Yuan, Wenyi Wei
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.) 380 (6652) (2023)
Tao Zhang, Daichao Xu, Elijah Trefts, Mingming Lv, Hiroyuki Inuzuka, Guobin Song, Min Liu, Jianlin Lu, Jianping Liu, Chen Chu, Min Wang, Huibing Wang, Huyan Meng, Hui Liu, Yuan Zhuang, Xingxing Xie, Fabin Dang, Dongxian Guan, Yuqin Men, Shuwen Jiang, Cong Jiang, Xiaoming Dai, Jing Liu, Zhen Wang, Peiqiang Yan, Jingchao Wang, Zhenbo Tu, Mrigya Babuta, Emily C Erickson, Alissandra L Hillis, Christian C Dibble, John M Asara, Gyongyi Szabo, Piotr Sicinski, Ji Miao, Yu-Ru Lee, Lifeng Pan, Reuben J Shaw, Junying Yuan, Wenyi Wei
Metabolic orchestration of cell death by AMPK-mediated phosphorylation of RIPK1. Science (New York, N.Y.) 380 (6652) (2023)
Jing Liu, Xia Bu, Chen Chu, Xiaoming Dai, John M Asara, Piotr Sicinski, Gordon J Freeman, Wenyi Wei
PRMT1 mediated methylation of cGAS suppresses anti-tumor immunity. Nature communications 14 (1) (2023)
Xiangling Xiao, Jie Shi, Chuan He, Xia Bu, Yishuang Sun, Minling Gao, Bolin Xiang, Wenjun Xiong, Panpan Dai, Qi Mao, Xixin Xing, Yingmeng Yao, Haisheng Yu, Gaoshan Xu, Siqi Li, Yan Ren, Baoxiang Chen, Congqing Jiang, Geng Meng, Yu-Ru Lee, Wenyi Wei, Gordon J Freeman, Conghua Xie, Jinfang Zhang
ERK and USP5 govern PD-1 homeostasis via deubiquitination to modulate tumor immunotherapy. Nature communications 14 (1) (2023)
Xueji Wu, Wei Xie, Wenxuan Xie, Wenyi Wei, Jian-Ping Guo
Beyond controlling cell size: functional analyses of S6K in tumorigenesis. Cell death & disease 13 (7) (2022)
Yunhua Peng, Jing Liu, Zhen Wang, Chun-Ping Cui, Tiantian Zhang, Shuangxi Zhang, Peipei Gao, Zhanwu Hou, Huadong Liu, Jian-Ping Guo, Jinfang Zhang, Yurong Wen, Wenyi Wei, Lingqiang Zhang, Jiankang Liu, Jiangang Long
Correction to: Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc. Cell death and differentiation (2022)
Yunhua Peng, Jing Liu, Zhen Wang, Chun-Ping Cui, Tiantian Zhang, Shuangxi Zhang, Peipei Gao, Zhanwu Hou, Huadong Liu, Jian-Ping Guo, Jinfang Zhang, Yurong Wen, Wenyi Wei, Lingqiang Zhang, Jiankang Liu, Jiangang Long
Prostate-specific oncogene OTUD6A promotes prostatic tumorigenesis via deubiquitinating and stabilizing c-Myc. Cell death and differentiation 29 (9) (2022)
Wenjun Xiong, Xueliang Gao, Tiantian Zhang, Baishan Jiang, Ming-Ming Hu, Xia Bu, Yang Gao, Lin-Zhou Zhang, Bo-Lin Xiao, Chuan He, Yishuang Sun, Haiou Li, Jie Shi, Xiangling Xiao, Bolin Xiang, Conghua Xie, Gang Chen, Haojian Zhang, Wenyi Wei, Gordon J Freeman, Hong-Bing Shu, Haizhen Wang, Jinfang Zhang
USP8 inhibition reshapes an inflamed tumor microenvironment that potentiates the immunotherapy. Nature communications 13 (1) (2022)
Liu Liu, Xiaoming Dai, Shasha Yin, Pengda Liu, Elizabeth G Hill, Wenyi Wei, Wenjian Gan
DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway. Science signaling 15 (715) (2022)
Jing Liu, Xufen Yu, He Chen, Husnu Ümit Kaniskan, Ling Xie, Xian Chen, Jian Jin, Wenyi Wei
TF-DUBTACs Stabilize Tumor Suppressor Transcription Factors. Journal of the American Chemical Society 144 (28) (2022)
Qiwei Jiang, Xiaomei Zhang, Xiaoming Dai, Shiyao Han, Xueji Wu, Lei Wang, Wenyi Wei, Ning Zhang, Wei Xie, Jian-Ping Guo
S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions. Nature communications 13 (1) (2022)
Jing Liu, He Chen, Husnu Ümit Kaniskan, Ling Xie, Xian Chen, Jian Jin, Wenyi Wei
TF-PROTACs Enable Targeted Degradation of Transcription Factors. Journal of the American Chemical Society 143 (23) (2021)
Fabin Dang, Li Nie, Jin Zhou, Kouhei Shimizu, Chen Chu, Zhong Wu, Anne Fassl, Shizhong Ke, Yuangao Wang, Jinfang Zhang, Tao Zhang, Zhenbo Tu, Hiroyuki Inuzuka, Piotr Sicinski, Adam J Bass, Wenyi Wei
Inhibition of CK1ε potentiates the therapeutic efficacy of CDK4/6 inhibitor in breast cancer. Nature communications 12 (1) (2021)
Jianping Guo, Ji Cheng, Nana Zheng, Xiaomei Zhang, Xiaoming Dai, Linli Zhang, Changjiang Hu, Xueji Wu, Qiwei Jiang, Depei Wu, Hitoshi Okada, Pier Paolo Pandolfi, Wenyi Wei
Copper Promotes Tumorigenesis by Activating the PDK1-AKT Oncogenic Pathway in a Copper Transporter 1 Dependent Manner. Advanced science (Weinheim, Baden-Wurttemberg, Germany) 8 (18) (2021)
Jing Liu, He Chen, Yi Liu, Yudao Shen, Fanye Meng, Husnu Ümit Kaniskan, Jian Jin, Wenyi Wei
Cancer Selective Target Degradation by Folate-Caged PROTACs. Journal of the American Chemical Society 143 (19) (2021)
Wenjuan Zhang, Lihui Li, Lili Cai, Yupei Liang, Junfeng Xu, Yue Liu, Lisha Zhou, Chen Ding, Yanmei Zhang, Hu Zhao, Jun Qin, Zhimin Shao, Wenyi Wei, Lijun Jia
Tumor-associated antigen Prame targets tumor suppressor p14/ARF for degradation as the receptor protein of CRL2Prame complex. Cell death and differentiation 28 (6) (2021)
He Chen, Jing Liu, Husnu Ümit Kaniskan, Wenyi Wei, Jian Jin
Folate-Guided Protein Degradation by Immunomodulatory Imide Drug-Based Molecular Glues and Proteolysis Targeting Chimeras. Journal of medicinal chemistry 64 (16) (2021)
Jing Liu, Collin Tokheim, Jonathan D Lee, Wenjian Gan, Brian J North, X Shirley Liu, Pier Paolo Pandolfi, Wenyi Wei
Genetic fusions favor tumorigenesis through degron loss in oncogenes. Nature communications 12 (1) (2021)
Xiaoming Dai, Jing Liu, Wenyi Wei
DUB-independent regulation of pVHL by OTUD6B suppresses hepatocellular carcinoma. Protein & cell 11 (8) (2021)
Wenjian Gan, Xiaoming Dai, Xiangpeng Dai, Jun Xie, Shasha Yin, Junjie Zhu, Chen Wang, Yuchen Liu, Jianping Guo, Min Wang, Jing Liu, Jia Hu, Ryan J Quinton, Neil J Ganem, Pengda Liu, John M Asara, Pier Paolo Pandolfi, Yingzi Yang, Zhigang He, Guangping Gao, Wenyi Wei
LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control. Nature cell biology 22 (2) (2020)
Zhiwei Wang, Yizuo Song, Miaomiao Ye, Xiaoming Dai, Xueqiong Zhu, Wenyi Wei
The diverse roles of SPOP in prostate cancer and kidney cancer. Nature reviews. Urology 17 (6) (2020)
Jing Liu, Yunhua Peng, Le Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long, Jianping Guo, Jinfang Zhang, Min Yuan, Shuangxi Zhang, Xun Wang, Jing Gao, Xiangpeng Dai, Shozo Furumoto, Lijun Jia, Pier Paolo Pandolfi, John M Asara, William G Kaelin, Jiankang Liu, Wenyi Wei
Author Correction: Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle. Cell research (2020)
Jianping Guo, Jing Liu, Wenyi Wei
Degrading proteins in animals: "PROTAC"tion goes in vivo. Cell research 29 (3) (2020)
Jing Liu, Yunhua Peng, Le Shi, Lixin Wan, Hiroyuki Inuzuka, Jiangang Long, Jianping Guo, Jinfang Zhang, Min Yuan, Shuangxi Zhang, Xun Wang, Jing Gao, Xiangpeng Dai, Shozo Furumoto, Lijun Jia, Pier Paolo Pandolfi, John M Asara, William G Kaelin, Jiankang Liu, Wenyi Wei
Skp2 dictates cell cycle-dependent metabolic oscillation between glycolysis and TCA cycle. Cell research 31 (1) (2020)
Yang Gao, Naoe Taira Nihira, Xia Bu, Chen Chu, Jinfang Zhang, Aleksandra Kolodziejczyk, Yizeng Fan, Ngai Ting Chan, Leina Ma, Jing Liu, Dong Wang, Xiaoming Dai, Huadong Liu, Masaya Ono, Akira Nakanishi, Hiroyuki Inuzuka, Brian J North, Yu-Han Huang, Samanta Sharma, Yan Geng, Wei Xu, X Shirley Liu, Lei Li, Yoshio Miki, Piotr Sicinski, Gordon J Freeman, Wenyi Wei
Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy. Nature cell biology 22 (9) (2020)
Fabin Dang, Li Nie, Wenyi Wei
Ubiquitin signaling in cell cycle control and tumorigenesis. Cell death and differentiation 28 (2) (2020)
Jing Liu, He Chen, Leina Ma, Zhixiang He, Dong Wang, Yi Liu, Qian Lin, Tinghu Zhang, Nathanael S Gray, H Ümit Kaniskan, Jian Jin, Wenyi Wei
Light-induced control of protein destruction by opto-PROTAC. Science advances 6 (8) (2020)
Giuseppe Novelli, Antonio Novelli, Paola Borgiani, Dario Cocciadiferro, Michela Biancolella, Emanuele Agolini, Marco Pietrosanto, Rosario Casalone, Manuela Helmer-Citterich, Emiliano Giardina, Suresh K Jain, Wenyi Wei, Charis Eng, Pier Paolo Pandolfi
WWP1 germline variants are associated with normocephalic autism spectrum disorder. Cell death & disease 11 (7) (2020)
Lihui Li, Wenjuan Zhang, Yue Liu, Xiaojun Liu, Lili Cai, Jihui Kang, Yunjing Zhang, Wenlian Chen, Changsheng Dong, Yanmei Zhang, Mingsong Wang, Wenyi Wei, Lijun Jia
The CRL3BTBD9 E3 ubiquitin ligase complex targets TNFAIP1 for degradation to suppress cancer cell migration. Signal transduction and targeted therapy 5 (1) (2020)
Lu Deng, Tong Meng, Lei Chen, Wenyi Wei, Ping Wang
The role of ubiquitination in tumorigenesis and targeted drug discovery. Signal transduction and targeted therapy 5 (1) (2020)
Jianping Guo, Xiangpeng Dai, Benoit Laurent, Nana Zheng, Wenjian Gan, Jian Zhang, Ailan Guo, Min Yuan, Pengda Liu, John M Asara, Alex Toker, Yang Shi, Pier Paolo Pandolfi, Wenyi Wei
AKT methylation by SETDB1 promotes AKT kinase activity and oncogenic functions. Nature cell biology 21 (2) (2019)
Yu-Ru Lee, Ming Chen, Jonathan D Lee, Jinfang Zhang, Shu-Yu Lin, Tian-Min Fu, Hao Chen, Tomoki Ishikawa, Shang-Yin Chiang, Jesse Katon, Yang Zhang, Yulia V Shulga, Assaf C Bester, Jacqueline Fung, Emanuele Monteleone, Lixin Wan, Chen Shen, Chih-Hung Hsu, Antonella Papa, John Gerard Clohessy, Julie Teruya-Feldstein, Suresh Jain, Hao Wu, Lydia E Matesic, Ruey-Hwa Chen, Wenyi Wei, Pier Paolo Pandolfi
Reactivation of PTEN tumor suppressor for cancer treatment through inhibition of a MYC-WWP1 inhibitory pathway. Science (New York, N.Y.) 364 (6441) (2019)
Bo Zhu, Shuyang Chen, Hongshen Wang, Chengqian Yin, Changpeng Han, Cong Peng, Zhaoqian Liu, Lixin Wan, Xiaoyang Zhang, Jie Zhang, Christine G Lian, Peilin Ma, Zhi-Xiang Xu, Sharon Prince, Tao Wang, Xiumei Gao, Yujiang Shi, Dali Liu, Min Liu, Wenyi Wei, Zhi Wei, Jingxuan Pan, Yongjun Wang, Zhenyu Xuan, Jay Hess, Nicholas K Hayward, Colin R Goding, Xiang Chen, Jun Zhou, Rutao Cui
The protective role of DOT1L in UV-induced melanomagenesis. Nature communications 9 (1) (2018)
Pengda Liu, Wenjian Gan, Siyuan Su, Arthur V Hauenstein, Tian-Min Fu, Bradley Brasher, Carsten Schwerdtfeger, Anthony C Liang, Ming Xu, Wenyi Wei
K63-linked polyubiquitin chains bind to DNA to facilitate DNA damage repair. Science signaling 11 (533) (2018)
Xiaoduo Xie, Hongli Hu, Xinyuan Tong, Long Li, Xiangyuan Liu, Min Chen, Huairui Yuan, Xia Xie, Qing-Run Li, Yuxue Zhang, Huafang Ouyang, Mengqi Wei, Jing Huang, Pengda Liu, Wenjian Gan, Yong Liu, Anyong Xie, Xiaoling Kuai, Gung-Wei Chirn, Hu Zhou, Rong Zeng, Ronggui Hu, Jun Qin, Fei-Long Meng, Wenyi Wei, Hongbin Ji, Daming Gao
The mTOR-S6K pathway links growth signalling to DNA damage response by targeting RNF168. Nature cell biology 20 (3) (2018)
Emilie Clement, Hiroyuki Inuzuka, Naoe Taira Nihira, Wenyi Wei, Alex Toker
Skp2-dependent reactivation of AKT drives resistance to PI3K inhibitors. Science signaling 11 (521) (2018)
Yuhan Chen, Qingyang Huang, Wen Liu, Qiong Zhu, Chun-Ping Cui, Liang Xu, Xing Guo, Ping Wang, Jingwen Liu, Guanglong Dong, Wenyi Wei, Cui Hua Liu, Zhichun Feng, Fuchu He, Lingqiang Zhang
Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth. Nature communications 9 (1) (2018)
Li-Yu Huang, Junjie Zhao, Hao Chen, Lixin Wan, Hiroyuki Inuzuka, Jianping Guo, Xuhong Fu, Yangyang Zhai, Zhaoning Lu, Xuefei Wang, Ze-Guang Han, Yihong Sun, Wenyi Wei
SCFFBW7-mediated degradation of Brg1 suppresses gastric cancer metastasis. Nature communications 9 (1) (2018)
Xiangpeng Dai, Wenjian Gan, Xiaoning Li, Shangqian Wang, Wei Zhang, Ling Huang, Shengwu Liu, Qing Zhong, Jianping Guo, Jinfang Zhang, Ting Chen, Kouhei Shimizu, Francisco Beca, Mirjam Blattner, Divya Vasudevan, Dennis L Buckley, Jun Qi, Lorenz Buser, Pengda Liu, Hiroyuki Inuzuka, Andrew H Beck, Liewei Wang, Peter J Wild, Levi A Garraway, Mark A Rubin, Christopher E Barbieri, Kwok-Kin Wong, Senthil K Muthuswamy, Jiaoti Huang, Yu Chen, James E Bradner, Wenyi Wei
Prostate cancer-associated SPOP mutations confer resistance to BET inhibitors through stabilization of BRD4. Nature medicine 23 (9) (2017)
Kouhei Shimizu, Hidefumi Fukushima, Kohei Ogura, Evan C Lien, Naoe Taira Nihira, Jinfang Zhang, Brian J North, Ailan Guo, Katsuyuki Nagashima, Tadashi Nakagawa, Seira Hoshikawa, Asami Watahiki, Koji Okabe, Aya Yamada, Alex Toker, John M Asara, Satoshi Fukumoto, Keiichi I Nakayama, Keiko Nakayama, Hiroyuki Inuzuka, Wenyi Wei
The SCFβ-TRCP E3 ubiquitin ligase complex targets Lipin1 for ubiquitination and degradation to promote hepatic lipogenesis. Science signaling 10 (460) (2017)
Naoe Taira Nihira, Kohei Ogura, Kouhei Shimizu, Brian J North, Jinfang Zhang, Daming Gao, Hiroyuki Inuzuka, Wenyi Wei
Acetylation-dependent regulation of MDM2 E3 ligase activity dictates its oncogenic function. Science signaling 10 (466) (2017)