Juan R Perilla

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 33

Top Topics

Molecular Dynamics

Structural Basis

Top Venues

Nature communications

Proceedings of the National Academy of Sciences of the United States of America

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Akshay Deshpande, Alexander J Bryer, Jonathan R Andino-Moncada, Jiong Shi, Jun Hong, Cameron Torres, Shimon Harel, Ashwanth C Francis, Juan R Perilla, Christopher Aiken, Itay Rousso
Elasticity of the HIV-1 core facilitates nuclear entry and infection. PLoS pathogens 20 (9) (2024)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio 14 (1) (2023)
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex B Kleinpeter, Sherimay Ablan, Hamed Meshkin, Juan R Perilla, Eric O Freed, Barbie K Ganser-Pornillos, Owen Pornillos, Angela M Gronenborn, Tatyana Polenova
Structural basis of HIV-1 maturation inhibitor binding and activity. Nature communications 14 (1) (2023)
Anna-Sophia Krebs, Hsuan-Fu Liu, Ye Zhou, Juan S Rey, Lev Levintov, Juan Shen, Andrew Howe, Juan R Perilla, Alberto Bartesaghi, Peijun Zhang
Molecular architecture and conservation of an immature human endogenous retrovirus. Nature communications 14 (1) (2023)
Qi Shen, Sushila Kumari, Chaoyi Xu, Sooin Jang, Jiong Shi, Ryan C Burdick, Lev Levintov, Qiancheng Xiong, Chunxiang Wu, Swapnil C Devarkar, Taoran Tian, Therese N Tripler, Yingxia Hu, Shuai Yuan, Joshua Temple, Qingzhou Feng, C Patrick Lusk, Christopher Aiken, Alan N Engelman, Juan R Perilla, Vinay K Pathak, Chenxiang Lin, Yong Xiong
The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Qi Shen, Sushila Kumari, Chaoyi Xu, Sooin Jang, Jiong Shi, Ryan C Burdick, Lev Levintov, Qiancheng Xiong, Chunxiang Wu, Swapnil C Devarkar, Taoran Tian, Therese N Tripler, Yingxia Hu, Shuai Yuan, Joshua Temple, Qingzhou Feng, C Patrick Lusk, Christopher Aiken, Alan N Engelman, Juan R Perilla, Vinay K Pathak, Chenxiang Lin, Yong Xiong
The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Alexander J Bryer, Juan S Rey, Juan R Perilla
Performance efficient macromolecular mechanics via sub-nanometer shape based coarse graining. Nature communications 14 (1) (2023)
Qi Shen, Sushila Kumari, Chaoyi Xu, Sooin Jang, Jiong Shi, Ryan C Burdick, Lev Levintov, Qiancheng Xiong, Chunxiang Wu, Swapnil C Devarkar, Taoran Tian, Therese N Tripler, Yingxia Hu, Shuai Yuan, Joshua Temple, Qingzhou Feng, C Patrick Lusk, Christopher Aiken, Alan N Engelman, Juan R Perilla, Vinay K Pathak, Chenxiang Lin, Yong Xiong
The capsid lattice engages a bipartite NUP153 motif to mediate nuclear entry of HIV-1 cores. Proceedings of the National Academy of Sciences of the United States of America 120 (13) (2023)
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex B Kleinpeter, Sherimay Ablan, Hamed Meshkin, Juan R Perilla, Eric O Freed, Barbie K Ganser-Pornillos, Owen Pornillos, Angela M Gronenborn, Tatyana Polenova
Structural basis of HIV-1 maturation inhibitor binding and activity. Nature communications 14 (1) (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio 14 (1) (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio 14 (1) (2023)
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex B Kleinpeter, Sherimay Ablan, Hamed Meshkin, Juan R Perilla, Eric O Freed, Barbie K Ganser-Pornillos, Owen Pornillos, Angela M Gronenborn, Tatyana Polenova
Structural basis of HIV-1 maturation inhibitor binding and activity. Nature communications 14 (1) (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio (2023)
Anna T Gres, Karen A Kirby, William M McFadden, Haijuan Du, Dandan Liu, Chaoyi Xu, Alexander J Bryer, Juan R Perilla, Jiong Shi, Christopher Aiken, Xiaofeng Fu, Peijun Zhang, Ashwanth C Francis, Gregory B Melikyan, Stefan G Sarafianos
Multidisciplinary studies with mutated HIV-1 capsid proteins reveal structural mechanisms of lattice stabilization. Nature communications 14 (1) (2023)
Alexander J Bryer, Tyler Reddy, Edward Lyman, Juan R Perilla
Full scale structural, mechanical and dynamical properties of HIV-1 liposomes. PLoS computational biology 18 (1) (2022)
Jodi Kraus, Ryan W Russell, Elena Kudryashova, Chaoyi Xu, Nidhi Katyal, Juan R Perilla, Dmitri S Kudryashov, Tatyana Polenova
Magic angle spinning NMR structure of human cofilin-2 assembled on actin filaments reveals isoform-specific conformation and binding mode. Nature communications 13 (1) (2022)
Muthukumar Balasubramaniam, Benem-Orom Davids, Alex Bryer, Chaoyi Xu, Santosh Thapa, Jiong Shi, Christopher Aiken, Jui Pandhare, Juan R Perilla, Chandravanu Dash
HIV-1 mutants that escape the cytotoxic T-lymphocytes are defective in viral DNA integration. PNAS nexus 1 (2) (2022)
Tyrone Thames, Alexander J Bryer, Xin Qiao, Jaekyun Jeon, Ryan Weed, Kaylie Janicki, Bingwen Hu, Peter L Gor'kov, Ivan Hung, Zhehong Gan, Juan R Perilla, Bo Chen
Curvature of the Retroviral Capsid Assembly Is Modulated by a Molecular Switch. The journal of physical chemistry letters 12 (32) (2021)
Chaoyi Xu, Nidhi Katyal, Tanya Nesterova, Juan R Perilla
Molecular determinants of Ebola nucleocapsid stability from molecular dynamics simulations. The Journal of chemical physics 153 (15) (2021)
Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Boecking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang
Structure of native HIV-1 cores and their interactions with IP6 and CypA. Science advances 7 (47) (2021)
Eric Wright, Mauricio H Ferrato, Alexander J Bryer, Robert Searles, Juan R Perilla, Sunita Chandrasekaran
Accelerating prediction of chemical shift of protein structures on GPUs: Using OpenACC. PLoS computational biology 16 (5) (2020)
Robert A Dick, Chaoyi Xu, Dustin R Morado, Vladyslav O Kravchuk, Clifton L Ricaña, Terri D Lyddon, Arianna M Broad, J Ryan Feathers, Marc C Johnson, Volker M Vogt, Juan R Perilla, John A G Briggs, Florian K M Schur
Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. PLoS pathogens 16 (1) (2020)
Manman Lu, Ryan W Russell, Alexander J Bryer, Caitlin M Quinn, Guang-Jin Hou, Huilan Zhang, Charles D Schwieters, Juan R Perilla, Angela M Gronenborn, Tatyana Polenova
Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR. Nature structural & molecular biology 27 (9) (2020)
Chaoyi Xu, Douglas K Fischer, Sanela Rankovic, Wen Li, Robert A Dick, Brent Runge, Roman Zadorozhnyi, Jinwoo Ahn, Christopher Aiken, Tatyana Polenova, Alan N Engelman, Zandrea Ambrose, Itay Rousso, Juan R Perilla
Permeability of the HIV-1 capsid to metabolites modulates viral DNA synthesis. PLoS biology 18 (12) (2020)
Alexander J Bryer, Jodi A Hadden, John E Stone, Juan R Perilla
High-Performance Analysis of Biomolecular Containers to Measure Small-Molecule Transport, Transbilayer Lipid Diffusion, and Protein Cavities. Journal of chemical information and modeling 59 (10) (2019)
Gino Cingolani, Michael McCauley, Anna Lobley, Alexander J Bryer, Jordan Wesolowski, Deanna L Greco, Ravi K Lokareddy, Erik Ronzone, Juan R Perilla, Fabienne Paumet
Structural basis for the homotypic fusion of chlamydial inclusions by the SNARE-like protein IncA. Nature communications 10 (1) (2019)
Caitlin M Quinn, Mingzhang Wang, Matthew P Fritz, Brent Runge, Jinwoo Ahn, Chaoyi Xu, Juan R Perilla, Angela M Gronenborn, Tatyana Polenova
Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 115 (45) (2018)
Jodi A Hadden, Juan R Perilla, Christopher John Schlicksup, Balasubramanian Venkatakrishnan, Adam Zlotnick, Klaus Schulten
All-atom molecular dynamics of the HBV capsid reveals insights into biological function and cryo-EM resolution limits. eLife 7 (2018)
Juan R Perilla, Gongpu Zhao, Manman Lu, Jiying Ning, Guangjin Hou, In-Ja L Byeon, Angela M Gronenborn, Tatyana Polenova, Peijun Zhang
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations. The journal of physical chemistry. B 121 (15) (2017)
Mingzhang Wang, Caitlin M Quinn, Juan R Perilla, Huilan Zhang, Randall Shirra, Z Conrad Zhang, In-Ja Byeon, Christopher L Suiter, Sherimay Ablan, Emiko Urano, Theodore J Nitz, Christopher Aiken, Eric O Freed, Peijun Zhang, Klaus Schulten, Angela M Gronenborn, Tatyana Polenova
Quenching protein dynamics interferes with HIV capsid maturation. Nature communications 8 (1) (2017)
Juan R Perilla, Klaus Schulten
Physical properties of the HIV-1 capsid from all-atom molecular dynamics simulations. Nature communications 8 (2017)
Frances J D Alvarez, Shaoda He, Juan R Perilla, Sooin Jang, Klaus Schulten, Alan N Engelman, Sjors H W Scheres, Peijun Zhang
CryoEM structure of MxB reveals a novel oligomerization interface critical for HIV restriction. Science advances 3 (9) (2017)
Manman Lu, Guangjin Hou, Huilan Zhang, Christopher L Suiter, Jinwoo Ahn, In-Ja L Byeon, Juan R Perilla, Christopher J Langmead, Ivan Hung, Peter L Gor'kov, Zhehong Gan, William Brey, Christopher Aiken, Peijun Zhang, Klaus Schulten, Angela M Gronenborn, Tatyana Polenova
Dynamic allostery governs cyclophilin A-HIV capsid interplay. Proceedings of the National Academy of Sciences of the United States of America 112 (47) (2015)