Mamuka Kvaratskhelia

ORCID

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 18

Top Venues

mBio

bioRxiv : the preprint server for biology

eLife

Science advances

University of Colorado Denver School of Medicine

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Colorado Denver School of Medicine Aug 14 2017

United States

Professor :: Medicine

Publications

Tao Jing, Zelin Shan, Tung Dinh, Avik Biswas, Sooin Jang, Juliet Greenwood, Min Li, Zeyuan Zhang, Gennavieve Gray, Hye Jeong Shin, Bo Zhou, Dario Oliveira Passos, Sriram Aiyer, Zhen Li, Robert Craigie, Alan N Engelman, Mamuka Kvaratskhelia, Dmitry Lyumkis
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding. bioRxiv : the preprint server for biology (2024)
Tao Jing, Zelin Shan, Tung Dinh, Avik Biswas, Sooin Jang, Juliet Greenwood, Min Li, Zeyuan Zhang, Gennavieve Gray, Hye Jeong Shin, Bo Zhou, Dario Oliveira Passos, Sriram Aiyer, Zhen Li, Robert Craigie, Alan N Engelman, Mamuka Kvaratskhelia, Dmitry Lyumkis
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding. bioRxiv : the preprint server for biology (2024)
Tung Dinh, Zahira Tber, Juan S Rey, Seema Mengshetti, Arun S Annamalai, Reed Haney, Lorenzo Briganti, Franck Amblard, James R Fuchs, Peter Cherepanov, Kyungjin Kim, Raymond F Schinazi, Juan R Perilla, Baek Kim, Mamuka Kvaratskhelia
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir. bioRxiv : the preprint server for biology (2024)
Tao Jing, Zelin Shan, Tung Dinh, Avik Biswas, Sooin Jang, Juliet Greenwood, Min Li, Zeyuan Zhang, Gennavieve Gray, Hye Jeong Shin, Bo Zhou, Dario Oliveira Passos, Sriram Aiyer, Zhen Li, Robert Craigie, Alan N Engelman, Mamuka Kvaratskhelia, Dmitry Lyumkis
Oligomeric HIV-1 Integrase Structures Reveal Functional Plasticity for Intasome Assembly and RNA Binding. bioRxiv : the preprint server for biology (2024)
Tung Dinh, Zahira Tber, Juan S Rey, Seema Mengshetti, Arun S Annamalai, Reed Haney, Lorenzo Briganti, Franck Amblard, James R Fuchs, Peter Cherepanov, Kyungjin Kim, Raymond F Schinazi, Juan R Perilla, Baek Kim, Mamuka Kvaratskhelia
The structural and mechanistic bases for the viral resistance to allosteric HIV-1 integrase inhibitor pirmitegravir. bioRxiv : the preprint server for biology (2024)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio 14 (1) (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio 14 (1) (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio 14 (1) (2023)
Matthew R Singer, Tung Dinh, Lev Levintov, Arun S Annamalai, Juan S Rey, Lorenzo Briganti, Nicola J Cook, Valerie E Pye, Ian A Taylor, Kyungjin Kim, Alan N Engelman, Baek Kim, Juan R Perilla, Mamuka Kvaratskhelia, Peter Cherepanov
The Drug-Induced Interface That Drives HIV-1 Integrase Hypermultimerization and Loss of Function. mBio (2023)
Min Li, Dario Oliveira Passos, Zelin Shan, Steven J Smith, Qinfang Sun, Avik Biswas, Indrani Choudhuri, Timothy S Strutzenberg, Allan Haldane, Nanjie Deng, Zhaoyang Li, Xue Zhi Zhao, Lorenzo Briganti, Mamuka Kvaratskhelia, Terrence R Burke, Ronald M Levy, Stephen H Hughes, Robert Craigie, Dmitry Lyumkis
Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants. Science advances 9 (29) (2023)
Stephanie M Bester, Daniel Adu-Ampratwum, Arun S Annamalai, Guochao Wei, Lorenzo Briganti, Bridget C Murphy, Reed Haney, James R Fuchs, Mamuka Kvaratskhelia
Structural and Mechanistic Bases of Viral Resistance to HIV-1 Capsid Inhibitor Lenacapavir. mBio 13 (5) (2022)
Guochao Wei, Naseer Iqbal, Valentine V Courouble, Ashwanth C Francis, Parmit Kumar Singh, Arpa Hudait, Arun S Annamalai, Stephanie M Bester, Szu-Wei Huang, Nikoloz Shkriabai, Lorenzo Briganti, Reed Haney, Vineet N KewalRamani, Gregory A Voth, Alan N Engelman, Gregory B Melikyan, Patrick R Griffin, Francisco Asturias, Mamuka Kvaratskhelia
Prion-like low complexity regions enable avid virus-host interactions during HIV-1 infection. Nature communications 13 (1) (2022)
Nicklas Sapp, Nathaniel Burge, Khan Cox, Prem Prakash, Muthukumar Balasubramaniam, Santosh Thapa, Devin Christensen, Min Li, Jared Linderberger, Mamuka Kvaratskhelia, Jui Pandhare, Robert Craigie, Michael G Poirier, Chandravanu Dash
HIV-1 Preintegration Complex Preferentially Integrates the Viral DNA into Nucleosomes Containing Trimethylated Histone 3-Lysine 36 Modification and Flanking Linker DNA. Journal of virology 96 (18) (2022)
Stephanie V Rebensburg, Guochao Wei, Ross C Larue, Jared Lindenberger, Ashwanth C Francis, Arun S Annamalai, James Morrison, Nikoloz Shkriabai, Szu-Wei Huang, Vineet KewalRamani, Eric M Poeschla, Gregory B Melikyan, Mamuka Kvaratskhelia
Sec24C is an HIV-1 host dependency factor crucial for virus replication. Nature microbiology 6 (4) (2021)
Jennifer L Elliott, Jenna E Eschbach, Pratibha C Koneru, Wen Li, Maritza Puray-Chavez, Dana Townsend, Dana Q Lawson, Alan N Engelman, Mamuka Kvaratskhelia, Sebla B Kutluay
Integrase-RNA interactions underscore the critical role of integrase in HIV-1 virion morphogenesis. eLife 9 (2020)
Stephanie M Bester, Guochao Wei, Haiyan Zhao, Daniel Adu-Ampratwum, Naseer Iqbal, Valentine V Courouble, Ashwanth C Francis, Arun S Annamalai, Parmit Kumar Singh, Nikoloz Shkriabai, Peter van Blerkom, James H Morrison, Eric M Poeschla, Alan N Engelman, Gregory B Melikyan, Patrick R Griffin, Joanna E Burdette, Francisco J Asturias, Mamuka Kvaratskhelia
Structural and mechanistic bases for a potent HIV-1 capsid inhibitor. Science (New York, N.Y.) 370 (6514) (2020)
Pratibha C Koneru, Ashwanth C Francis, Nanjie Deng, Stephanie V Rebensburg, Ashley C Hoyte, Jared Lindenberger, Daniel Adu-Ampratwum, Ross C Larue, Michael F Wempe, Alan N Engelman, Dmitry Lyumkis, James R Fuchs, Ronald M Levy, Gregory B Melikyan, Mamuka Kvaratskhelia
HIV-1 integrase tetramers are the antiviral target of pyridine-based allosteric integrase inhibitors. eLife 8 (2019)

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Publication Activity (10 Years)

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Mamuka Kvaratskhelia