John A G Briggs (John Ag Briggs)

Publication Activity (10 Years)

Years Active: 2017-2023
Publications (10 Years): 42

Top Topics

Men Who Have Sex With Men

Hepatitis C Virus

Electron Microscopy

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science advances

This page only lists publications with an associated author ORCID identifier.

Publications

Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Junjie Xu, Simon Erlendsson, Manvendra Singh, Matthew Regier, Iosune Ibiricu, Gregory S Day, Amanda L Piquet, Stacey L Clardy, Cedric Feschotte, John A G Briggs, Jason D Shepherd
PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome. bioRxiv : the preprint server for biology (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Junjie Xu, Simon Erlendsson, Manvendra Singh, Matthew Regier, Iosune Ibiricu, Gregory S Day, Amanda L Piquet, Stacey L Clardy, Cedric Feschotte, John A G Briggs, Jason D Shepherd
PNMA2 forms non-enveloped virus-like capsids that trigger paraneoplastic neurological syndrome. bioRxiv : the preprint server for biology (2023)
Katherine U Gaynor, Marina Vaysburd, Maximilian A J Harman, Anna Albecka, Phillip Jeffrey, Paul Beswick, Guido Papa, Liuhong Chen, Donna L Mallery, Brian McGuinness, Katerine Van Rietschoten, Steven Stanway, Paul D Brear, Aleksei Lulla, Katarzyna A Ciazynska, Veronica T Chang, Joanne Sharp, Megan Neary, Helen Box, Jo Herriott, Edyta Kijak, Lee Tatham, Eleanor G Bentley, Parul Sharma, Adam Kirby, Ximeng Han, James P Stewart, Andrew Owen, John A G Briggs, Marko Hyvönen, Michael J Skynner, Leo C James
Multivalent bicyclic peptides are an effective antiviral modality that can potently inhibit SARS-CoV-2. Nature communications 14 (1) (2023)
James C V Stacey, Aaron Wai Kit Tan, John M Lu, Leo C James, Robert A Dick, John A G Briggs
Two structural switches in HIV-1 capsid regulate capsid curvature and host factor binding. Proceedings of the National Academy of Sciences of the United States of America 120 (16) (2023)
Carolyn M Highland, Aaron Wai Kit Tan, Clifton L Ricaña, John A G Briggs, Robert A Dick
Structural insights into HIV-1 polyanion-dependent capsid lattice formation revealed by single particle cryo-EM. Proceedings of the National Academy of Sciences of the United States of America 120 (18) (2023)
Jasenko Zivanov, Joaquin Otón, Zunlong Ke, Andriko von Kügelgen, Euan Pyle, Kun Qu, Dustin Morado, Daniel Castaño-Díez, Giulia Zanetti, Tanmay A M Bharat, John A G Briggs, Sjors H W Scheres
A Bayesian approach to single-particle electron cryo-tomography in RELION-4.0. eLife 11 (2022)
Alexander J Pak, Alvin Yu, Zunlong Ke, John A G Briggs, Gregory A Voth
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core. Nature communications 13 (1) (2022)
Ping He, Banghui Liu, Xijie Gao, Qihong Yan, Rongjuan Pei, Jing Sun, Qiuluan Chen, Ruitian Hou, Zimu Li, Yanjun Zhang, Jin-Cun Zhao, Hao Sun, Bo Feng, Qian Wang, Haisu Yi, Peiyu Hu, Pingchao Li, Yudi Zhang, Zhilong Chen, Xuefeng Niu, Xiaolin Zhong, Liang Jin, Xiaofeng Liu, Kun Qu, Katarzyna A Ciazynska, Andrew P Carter, John A G Briggs, Jizheng Chen, Jin-Song Liu, Xinwen Chen, Jun He, Ling Chen, Xiaoli Xiong
SARS-CoV-2 Delta and Omicron variants evade population antibody response by mutations in a single spike epitope. Nature microbiology 7 (10) (2022)
Rebecca J Taylor, Grigory Tagiltsev, John A G Briggs
The structure of COPI vesicles and regulation of vesicle turnover. FEBS letters (2022)
Kun Qu, Qiuluan Chen, Katarzyna A Ciazynska, Banghui Liu, Xixi Zhang, Jingjing Wang, Yujie He, Jiali Guan, Jun He, Tian Liu, Xiaofei Zhang, Andrew P Carter, Xiaoli Xiong, John A G Briggs
Engineered disulfide reveals structural dynamics of locked SARS-CoV-2 spike. PLoS pathogens 18 (7) (2022)
Rebecca J Taylor, Grigory Tagiltsev, John A G Briggs
The structure of COPI vesicles and regulation of vesicle turnover. FEBS letters (2022)
Alvin Yu, Elizabeth M Y Lee, John A G Briggs, Barbie K Ganser-Pornillos, Owen Pornillos, Gregory A Voth
Strain and rupture of HIV-1 capsids during uncoating. Proceedings of the National Academy of Sciences of the United States of America 119 (10) (2022)
Julia T Peukes, Xiaoli Xiong, John A G Briggs
New structural insights into the multifunctional influenza A matrix protein 1. FEBS letters 595 (20) (2021)
Shirley Tremel, Yohei Ohashi, Dustin R Morado, Jessie Bertram, Olga Perisic, Laura T L Brandt, Marie-Kristin von Wrisberg, Zhuo A Chen, Sarah L Maslen, Oleksiy Kovtun, J Mark Skehel, Juri Rappsilber, Kathrin Lang, Sean Munro, John A G Briggs, Roger L Williams
Structural basis for VPS34 kinase activation by Rab1 and Rab5 on membranes. Nature communications 12 (1) (2021)
Kun Qu, Zunlong Ke, Vojtech Zila, Maria Anders-Össwein, Bärbel Glass, Frauke Mücksch, Rainer Müller, Carsten Schultz, Barbara Müller, Hans-Georg Kräusslich, John A G Briggs
Maturation of the matrix and viral membrane of HIV-1. Science (New York, N.Y.) 373 (6555) (2021)
Donna L Mallery, Alex B Kleinpeter, Nadine Renner, K M Rifat Faysal, Mariia Novikova, Leo Kiss, Miranda S C Wilson, Bilal Ahsan, Zunlong Ke, John A G Briggs, Adolfo Saiardi, Till Boecking, Eric O Freed, Leo C James
A stable immature lattice packages IP6 for HIV capsid maturation. Science advances 7 (11) (2021)
Natalya Leneva, Oleksiy Kovtun, Dustin R Morado, John A G Briggs, David J Owen
Architecture and mechanism of metazoan retromer:SNX3 tubular coat assembly. Science advances 7 (13) (2021)
Alexander J Pak, Alvin Yu, Zunlong Ke, John A G Briggs, Gregory A Voth
Cooperative multivalent receptor binding promotes exposure of the SARS-CoV-2 fusion machinery core. bioRxiv : the preprint server for biology (2021)
Steven A Kemp, Dami Aderonke Collier, Rawlings P Datir, Isabella A T M Ferreira, Salma Gayed, Aminu S Jahun, Myra Hosmillo, Chloe Rees-Spear, Petra Mlcochova, Ines Ushiro Lumb, David J Roberts, Anita Chandra, Nigel J Temperton, null null, null null, Katherine Sharrocks, Elizabeth Blane, Yorgo Modis, Kendra E Leigh, John A G Briggs, Marit J van Gils, Kenneth G C Smith, John R Bradley, Chris Smith, Rainer Doffinger, Lourdes Ceron-Gutierrez, Gabriela Barcenas-Morales, David D Pollock, Richard A Goldstein, Anna Smielewska, Jordan Peter Skittrall, Theodore Gouliouris, Ian G Goodfellow, Effrossyni Gkrania-Klotsas, Christopher J R Illingworth, Laura E McCoy, Ravindra Kumar Gupta
SARS-CoV-2 evolution during treatment of chronic infection. Nature 592 (7853) (2021)
Aaron Wai Kit Tan, Alexander J Pak, Dustin R Morado, Gregory A Voth, John A G Briggs
Immature HIV-1 assembles from Gag dimers leaving partial hexamers at lattice edges as potential substrates for proteolytic maturation. Proceedings of the National Academy of Sciences of the United States of America 118 (3) (2021)
Oleksiy Kovtun, Veronica Kane Dickson, Bernard T Kelly, David J Owen, John A G Briggs
Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles. Science advances 6 (30) (2020)
Robert A Dick, Chaoyi Xu, Dustin R Morado, Vladyslav O Kravchuk, Clifton L Ricaña, Terri D Lyddon, Arianna M Broad, J Ryan Feathers, Marc C Johnson, Volker M Vogt, Juan R Perilla, John A G Briggs, Florian K M Schur
Structures of immature EIAV Gag lattices reveal a conserved role for IP6 in lentivirus assembly. PLoS pathogens 16 (1) (2020)
Simon Erlendsson, Dustin R Morado, Harrison B Cullen, Cedric Feschotte, Jason D Shepherd, John A G Briggs
Structures of virus-like capsids formed by the Drosophila neuronal Arc proteins. Nature neuroscience 23 (2) (2020)
Zunlong Ke, Joaquin Otón, Kun Qu, Mirko Cortese, Vojtech Zila, Lesley McKeane, Takanori Nakane, Jasenko Zivanov, Christopher John Neufeldt, Berati Cerikan, John M Lu, Julia Peukes, Xiaoli Xiong, Hans-Georg Kräusslich, Sjors H W Scheres, Ralf F W Bartenschlager, John A G Briggs
Structures and distributions of SARS-CoV-2 spike proteins on intact virions. Nature 588 (7838) (2020)
Julia T Peukes, Xiaoli Xiong, Simon Erlendsson, Kun Qu, William Wan, Leslie J Calder, Oliver Schraidt, Susann Kummer, Stefan M V Freund, Hans-Georg Kräusslich, John A G Briggs
The native structure of the assembled matrix protein 1 of influenza A virus. Nature 587 (7834) (2020)
Lucy Ginger, Joerg Malsam, Andreas F-P Sonnen, Dustin Morado, Andrea Scheutzow, Thomas H Söllner, John A G Briggs
Arrangements of proteins at reconstituted synaptic vesicle fusion sites depend on membrane separation. FEBS letters 594 (21) (2020)
Xiaoli Xiong, Kun Qu, Katarzyna A Ciazynska, Myra Hosmillo, Andrew P Carter, Soraya Ebrahimi, Zunlong Ke, Sjors H W Scheres, Laura Bergamaschi, Guinevere L Grice, Ying Zhang, null null, James A Nathan, Stephen Baker, Leo C James, Helen E Baxendale, Ian Goodfellow, Rainer Doffinger, John A G Briggs
A thermostable, closed SARS-CoV-2 spike protein trimer. Nature structural & molecular biology 27 (10) (2020)
William Wan, Mairi Clarke, Michael J Norris, Larissa Kolesnikova, Alexander Koehler, Zachary A Bornholdt, Stephan Becker, Erica Ollmann Saphire, John A G Briggs
Ebola and Marburg virus matrix layers are locally ordered assemblies of VP40 dimers. eLife 9 (2020)
Lauren Ann Metskas, John A G Briggs
Fluorescence-Based Detection of Membrane Fusion State on a Cryo-EM Grid using Correlated Cryo-Fluorescence and Cryo-Electron Microscopy. Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada 25 (4) (2019)
Svetlana O Dodonova, Simone Prinz, Virginia Bilanchone, Suzanne Sandmeyer, John A G Briggs
Structure of the Ty3/Gypsy retrotransposon capsid and the evolution of retroviruses. Proceedings of the National Academy of Sciences of the United States of America 116 (20) (2019)
Yury S Bykov, Nir Cohen, Natalia Gabrielli, Hetty E Manenschijn, Sonja Welsch, Petr Chlanda, Wanda Kukulski, Kiran R Patil, Maya Schuldiner, John A G Briggs
High-throughput ultrastructure screening using electron microscopy and fluorescent barcoding. The Journal of cell biology 218 (8) (2019)
Kun Qu, Bärbel Glass, Michal Doležal, Florian K M Schur, Brice Murciano, Alan Rein, Michaela Rumlová, Tomáš Ruml, Hans-Georg Kräusslich, John A G Briggs
Structure and architecture of immature and mature murine leukemia virus capsids. Proceedings of the National Academy of Sciences of the United States of America 115 (50) (2018)
Simone Mattei, Aaron Tan, Bärbel Glass, Barbara Müller, Hans-Georg Kräusslich, John A G Briggs
High-resolution structures of HIV-1 Gag cleavage mutants determine structural switch for virus maturation. Proceedings of the National Academy of Sciences of the United States of America 115 (40) (2018)
Yury S Bykov, Miroslava Schaffer, Svetlana O Dodonova, Sahradha Albert, Juergen M Plitzko, Wolfgang Baumeister, Benjamin D Engel, John A G Briggs
The structure of the COPI coat determined within the cell. eLife 6 (2017)
Svetlana O Dodonova, Patrick Aderhold, Juergen Kopp, Iva Ganeva, Simone Röhling, Wim J H Hagen, Irmgard Sinning, Felix Wieland, John A G Briggs
9Å structure of the COPI coat reveals that the Arf1 GTPase occupies two contrasting molecular environments. eLife 6 (2017)