Michael W Parker (Lorien J Parker)

ResearcherID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2015-2024
Publications (10 Years): 44

Top Topics

Low Density Lipoprotein

Men Who Have Sex With Men

Top Venues

Nature communications

Chemical communications (Cambridge, England)

Cell death & disease

This page only lists publications with an associated author ORCID identifier.

Publications

Hunter L Abrahamsen, Tristan C Sanford, Casie E Collamore, Bronte A Johnstone, Michael J Coyne, Leonor García-Bayona, Michelle P Christie, Jordan C Evans, Allison J Farrand, Katia Flores, Craig J Morton, Michael W Parker, Laurie E Comstock, Rodney K Tweten
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria. Nature communications 15 (1) (2024)
Thomas S Fulford, Caroline Soliman, Rebecca G Castle, Marc Rigau, Zheng Ruan, Olan Dolezal, Rebecca Seneviratna, Hamish G Brown, Eric Hanssen, Andrew Hammet, Shihan Li, Samuel J Redmond, Amy W Chung, Michael A Gorman, Michael W Parker, Onisha Patel, Thomas S Peat, Janet Newman, Andreas Behren, Nicholas A Gherardin, Dale I Godfrey, Adam P Uldrich
Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers. Nature immunology 25 (8) (2024)
Hunter L Abrahamsen, Tristan C Sanford, Casie E Collamore, Bronte A Johnstone, Michael J Coyne, Leonor García-Bayona, Michelle P Christie, Jordan C Evans, Allison J Farrand, Katia Flores, Craig J Morton, Michael W Parker, Laurie E Comstock, Rodney K Tweten
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria. Nature communications 15 (1) (2024)
Thomas S Fulford, Caroline Soliman, Rebecca G Castle, Marc Rigau, Zheng Ruan, Olan Dolezal, Rebecca Seneviratna, Hamish G Brown, Eric Hanssen, Andrew Hammet, Shihan Li, Samuel J Redmond, Amy W Chung, Michael A Gorman, Michael W Parker, Onisha Patel, Thomas S Peat, Janet Newman, Andreas Behren, Nicholas A Gherardin, Dale I Godfrey, Adam P Uldrich
Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers. Nature immunology (2024)
K M Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Andrew J Tuckwell, Michelle P Christie, Michael W Parker, Stuart G Turville, Greg J Towers, Leo C James, David A Jacques, Till Boecking
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure. eLife 13 (2024)
K M Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Andrew J Tuckwell, Michelle P Christie, Michael W Parker, Stuart G Turville, Greg J Towers, Leo C James, David A Jacques, Till Boecking
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure. eLife 13 (2024)
Rhynelle S Dmello, Michelle Palmieri, Pathum S Thilakasiri, Larissa Doughty, Tracy L Nero, Ashleigh R Poh, Sarah Q To, Erinna F Lee, Walter Douglas Fairlie, Lisa A Mielke, Michael W Parker, Ivan K H Poon, Eduard Batlle, Matthias Ernst, Ashwini L Chand
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer. Cell death & disease 15 (4) (2024)
Rhynelle S Dmello, Michelle Palmieri, Pathum S Thilakasiri, Larissa Doughty, Tracy L Nero, Ashleigh R Poh, Sarah Q To, Erinna F Lee, Walter Douglas Fairlie, Lisa A Mielke, Michael W Parker, Ivan K H Poon, Eduard Batlle, Matthias Ernst, Ashwini L Chand
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer. Cell death & disease 15 (4) (2024)
Hunter L Abrahamsen, Tristan C Sanford, Casie E Collamore, Bronte A Johnstone, Michael J Coyne, Leonor García-Bayona, Michelle P Christie, Jordan C Evans, Allison J Farrand, Katia Flores, Craig J Morton, Michael W Parker, Laurie E Comstock, Rodney K Tweten
Distant relatives of a eukaryotic cell-specific toxin family evolved a complement-like mechanism to kill bacteria. Nature communications 15 (1) (2024)
Thomas S Fulford, Caroline Soliman, Rebecca G Castle, Marc Rigau, Zheng Ruan, Olan Dolezal, Rebecca Seneviratna, Hamish G Brown, Eric Hanssen, Andrew Hammet, Shihan Li, Samuel J Redmond, Amy W Chung, Michael A Gorman, Michael W Parker, Onisha Patel, Thomas S Peat, Janet Newman, Andreas Behren, Nicholas A Gherardin, Dale I Godfrey, Adam P Uldrich
Vγ9Vδ2 T cells recognize butyrophilin 2A1 and 3A1 heteromers. Nature immunology 25 (8) (2024)
Rhynelle S Dmello, Michelle Palmieri, Pathum S Thilakasiri, Larissa Doughty, Tracy L Nero, Ashleigh R Poh, Sarah Q To, Erinna F Lee, Walter Douglas Fairlie, Lisa A Mielke, Michael W Parker, Ivan K H Poon, Eduard Batlle, Matthias Ernst, Ashwini L Chand
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer. Cell death & disease 15 (4) (2024)
K M Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Andrew J Tuckwell, Michelle P Christie, Michael W Parker, Stuart G Turville, Greg J Towers, Leo C James, David A Jacques, Till Boecking
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure. eLife 13 (2024)
Rhynelle S Dmello, Michelle Palmieri, Pathum S Thilakasiri, Larissa Doughty, Tracy L Nero, Ashleigh R Poh, Sarah Q To, Erinna F Lee, Walter Douglas Fairlie, Lisa A Mielke, Michael W Parker, Ivan K H Poon, Eduard Batlle, Matthias Ernst, Ashwini L Chand
Combination of bazedoxifene with chemotherapy and SMAC-mimetics for the treatment of colorectal cancer. Cell death & disease 15 (4) (2024)
K M Rifat Faysal, James C Walsh, Nadine Renner, Chantal L Márquez, Vaibhav B Shah, Andrew J Tuckwell, Michelle P Christie, Michael W Parker, Stuart G Turville, Greg J Towers, Leo C James, David A Jacques, Till Boecking
Pharmacologic hyperstabilisation of the HIV-1 capsid lattice induces capsid failure. eLife 13 (2024)
Catherine G Fitzgerald Dickmann, Alexander Franklin McDonald, Nhi Huynh, Angela Rigopoulos, Zhanqi Liu, Nancy Guo, Laura D Osellame, Michael A Gorman, Michael W Parker, Hui Kong Gan, Andrew Mark Scott, Uwe Ackermann, Ingrid Julienne Georgette Burvenich, Jonathan M White
Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chemical communications (Cambridge, England) 59 (21) (2023)
Catherine G Fitzgerald Dickmann, Alexander Franklin McDonald, Nhi Huynh, Angela Rigopoulos, Zhanqi Liu, Nancy Guo, Laura D Osellame, Michael A Gorman, Michael W Parker, Hui Kong Gan, Andrew Mark Scott, Uwe Ackermann, Ingrid Julienne Georgette Burvenich, Jonathan M White
Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chemical communications (Cambridge, England) (2023)
Catherine G Fitzgerald Dickmann, Alexander Franklin McDonald, Nhi Huynh, Angela Rigopoulos, Zhanqi Liu, Nancy Guo, Laura D Osellame, Michael A Gorman, Michael W Parker, Hui Kong Gan, Andrew Mark Scott, Uwe Ackermann, Ingrid Julienne Georgette Burvenich, Jonathan M White
Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chemical communications (Cambridge, England) 59 (21) (2023)
Winnie L Kan, Urmi Dhagat, Kerstin B Kaufmann, Timothy R Hercus, Tracy L Nero, Andy G X Zeng, John Toubia, Emma F Barry, Sophie E Broughton, Guillermo A Gomez, Brooks A Benard, Mara Dottore, Karen S Cheung Tung Shing, Helena Boutzen, Saumya E E Samaraweera, Kaylene J Simpson, Liqing Jin, Gregory J Goodall, C Glenn Begley, Daniel Thomas, Paul G Ekert, Denis Tvorogov, Richard J J D'Andrea, John E Dick, Michael W Parker, Angel F Lopez
Distinct assemblies of heterodimeric cytokine receptors govern stemness programs in leukemia. Cancer discovery (2023)
Catherine G Fitzgerald Dickmann, Alexander Franklin McDonald, Nhi Huynh, Angela Rigopoulos, Zhanqi Liu, Nancy Guo, Laura D Osellame, Michael A Gorman, Michael W Parker, Hui Kong Gan, Andrew Mark Scott, Uwe Ackermann, Ingrid Julienne Georgette Burvenich, Jonathan M White
Bromodomain and extraterminal protein-targeted probe enables tumour visualisation in vivo using positron emission tomography. Chemical communications (Cambridge, England) 59 (21) (2023)
Riley D Metcalfe, Eric Hanssen, Ka Yee Fung, Kaheina Aizel, Clara C Kosasih, Courtney O Zlatic, Larissa Doughty, Craig J Morton, Andrew P Leis, Michael W Parker, Paul R Gooley, Tracy L Putoczki, Michael D W Griffin
Structures of the interleukin 11 signalling complex reveal gp130 dynamics and the inhibitory mechanism of a cytokine variant. Nature communications 14 (1) (2023)
Conall McGuinness, James C Walsh, Charles Bayly-Jones, Michelle A Dunstone, Michelle P Christie, Craig J Morton, Michael W Parker, Till Boecking
Single-molecule analysis of the entire perfringolysin O pore formation pathway. eLife 11 (2022)
Stanley C Xie, Riley D Metcalfe, Elyse A Dunn, Craig J Morton, Shih-Chung Huang, Tanya Puhalovich, Yawei Du, Sergio Wittlin, Shuai Nie, Madeline R Luth, Liting Ma, Mi-Sook Kim, Charisse Flerida A Pasaje, Krittikorn Kumpornsin, Carlo Giannangelo, Fiona J Houghton, Alisje Churchyard, Mufuliat T Famodimu, Daniel C Barry, David L Gillett, Sumanta Dey, Clara C Kosasih, William Newman, Jacquin C Niles, Marcus Chee San Lee, Jake Baum, Sabine Ottilie, Elizabeth A Winzeler, Darren John Creek, Nicholas A Williamson, Michael W Parker, Stephen Brand, Steven P Langston, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Reaction hijacking of tyrosine tRNA synthetase as a new whole-of-life-cycle antimalarial strategy. Science (New York, N.Y.) 376 (6597) (2022)
Johannes Zeller, Karen S Cheung Tung Shing, Tracy L Nero, James D McFadyen, Guy Krippner, Balázs Bogner, Sheena Kreuzaler, Jurij Kiefer, Verena K Horner, David Braig, Habiba Danish, Sara Baratchi, Mark Fricke, Xiaowei Wang, Michel G Kather, Bernd Kammerer, Kevin J Woollard, Prerna Sharma, Craig J Morton, Geoffrey Pietersz, Michael W Parker, Karlheinz Peter, Steffen U Eisenhardt
A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein. EMBO molecular medicine (2022)
Charlotte Hodson, Jason K K Low, Sylvie Van Twest, Samuel E Jones, Paolo Swuec, Vincent J Murphy, Kaima Tsukada, Matthew Fawkes, Rohan Bythell-Douglas, Adelina Davies, Jessica K Holien, Julienne J O'Rourke, Benjamin L Parker, Astrid Glaser, Michael W Parker, Joel P Mackay, Andrew N Blackford, Alessandro Costa, Andrew J Deans
Mechanism of Bloom syndrome complex assembly required for double Holliday junction dissolution and genome stability. Proceedings of the National Academy of Sciences of the United States of America 119 (6) (2022)
Bronte A Johnstone, Riya Joseph, Michelle P Christie, Craig J Morton, Conall McGuiness, James C Walsh, Till Böcking, Rodney K Tweten, Michael W Parker
Cholesterol-dependent cytolysins: The outstanding questions. IUBMB life 74 (12) (2022)
C Glenn Begley, Mark Ashton, Jonathan B Baell, Michael Bettess, Michael P Brown, Brett Carter, William N Charman, Christopher Davis, Simon Fisher, Ian Hector Frazer, Anand Gautam, Michael P Jennings, Philip Kearney, Eloise Keeffe, Darren Kelly, Angel F Lopez, Michael A McGuckin, Michael W Parker, Craig Rayner, Brett Roberts, James S Rush, Mark Sullivan
Drug repurposing: Misconceptions, challenges, and opportunities for academic researchers. Science translational medicine 13 (612) (2021)
Stefan J Hermans, Tracy L Nero, Craig J Morton, Jonathan H Gooi, Gabriela A N Crespi, Nancy C Hancock, Chen Gao, Kenta Ishii, Jasmina Markulić, Michael W Parker
Structural biology of cell surface receptors implicated in Alzheimer's disease. Biophysical reviews 14 (1) (2021)
Stanley C Xie, Riley D Metcalfe, Hirotake Mizutani, Tanya Puhalovich, Eric Hanssen, Craig J Morton, Yawei Du, Con Dogovski, Shih-Chung Huang, Jeffrey Ciavarri, Paul Hales, Robert J Griffin, Lawrence H Cohen, Bei-Ching Chuang, Sergio Wittlin, Ioanna Deni, Tomas Yeo, Kurt E Ward, Daniel C Barry, Boyin Liu, David L Gillett, Benigno F Crespo-Fernandez, Sabine Ottilie, Nimisha Mittal, Alisje Churchyard, Daniel Ferguson, Anna Caroline Campos Aguiar, Rafael Victorio Carvalho Guido, Jake Baum, Kirsten K Hanson, Elizabeth A Winzeler, Francisco Javier Gamo, David A Fidock, Delphine Baud, Michael W Parker, Stephen Brand, Lawrence R Dick, Michael D W Griffin, Alexandra E Gould, Leann Tilley
Design of proteasome inhibitors with oral efficacy in vivo against Plasmodium falciparum and selectivity over the human proteasome. Proceedings of the National Academy of Sciences of the United States of America 118 (39) (2021)
Tao Ni, Yanan Zhu, Zhengyi Yang, Chaoyi Xu, Yuriy Chaban, Tanya Nesterova, Jiying Ning, Till Boecking, Michael W Parker, Christina Monnie, Jinwoo Ahn, Juan R Perilla, Peijun Zhang
Structure of native HIV-1 cores and their interactions with IP6 and CypA. Science advances 7 (47) (2021)
Zsuzsanna Nagy, Janith A Seneviratne, Maxwell Kanikevich, William Chang, Chelsea Mayoh, Pooja Venkat, Yanhua Du, Changhong Wang, Alice Salib, Jessica Koach, Daniel R Carter, Rituparna Mittra, Tao Liu, Michael W Parker, Belamy B Cheung, Glenn M Marshall
An ALYREF-MYCN coactivator complex drives neuroblastoma tumorigenesis through effects on USP3 and MYCN stability. Nature communications 12 (1) (2021)
Winnie Tan, Sylvie Van Twest, Andrew Leis, Rohan Bythell-Douglas, Vincent J Murphy, Michael F Sharp, Michael W Parker, Wayne Crismani, Andrew J Deans
Monoubiquitination by the human Fanconi anemia core complex clamps FANCI:FANCD2 on DNA in filamentous arrays. eLife 9 (2020)
Stephen L Pinkosky, John W Scott, Eric M Desjardins, Brennan K Smith, Emily Anne Day, Rebecca J Ford, Christopher G Langendorf, Naomi X Y Ling, Tracy L Nero, Kim Loh, Sandra Galic, Ashfaqul Hoque, William J Smiles, Kevin R W Ngoei, Michael W Parker, Yan Yan, Karsten Melcher, Bruce E Kemp, Jonathan S Oakhill, Gregory R Steinberg
Long-chain fatty acyl-CoA esters regulate metabolism via allosteric control of AMPK β1 isoforms. Nature metabolism 2 (9) (2020)
Winnie Tan, Vincent J Murphy, Aude Charron, Sylvie van Twest, Michael F Sharp, Angelos Constantinou, Michael W Parker, Wayne Crismani, Rohan Bythell-Douglas, Andrew J Deans
Preparation and purification of mono-ubiquitinated proteins using Avi-tagged ubiquitin. PloS one 15 (2) (2020)
Anastasia De Luca, Lorien J Parker, Wee Han Ang, Carlo Rodolfo, Valentina Gabbarini, Nancy C Hancock, Francesca Palone, Anna P Mazzetti, Laure Menin, Craig J Morton, Michael W Parker, Mario Lo Bello, Paul J Dyson
A structure-based mechanism of cisplatin resistance mediated by glutathione transferase P1-1. Proceedings of the National Academy of Sciences of the United States of America 116 (28) (2019)
Craig J Morton, Marc-Antoine Sani, Michael W Parker, Frances Separovic
Cholesterol-Dependent Cytolysins: Membrane and Protein Structural Requirements for Pore Formation. Chemical reviews 119 (13) (2019)
Jessica Koach, Jessica K Holien, Hassina Massudi, Daniel R Carter, Olivia C Ciampa, Mika Herath, Taylor Lim, Janith A Seneviratne, Giorgio Milazzo, Jayne E Murray, Joshua A McCarroll, Bing Liu, Chelsea Mayoh, Bryce Keenan, Brendan W Stevenson, Michael A Gorman, Jessica Lilian Bell, Larissa Doughty, Stefan Hüttelmaier, Andre Oberthuer, Matthias Fischer, Andrew J Gifford, Tao Liu, Xiaoling Zhang, Shizhen Zhu, W Clay Gustafson, Michelle Haber, Murray D Norris, Jamie I Fletcher, Giovanni Perini, Michael W Parker, Belamy B Cheung, Glenn M Marshall
Drugging MYCN Oncogenic Signaling through the MYCN-PA2G4 Binding Interface. Cancer research 79 (21) (2019)
Chantal L Márquez, Derrick Lau, James Walsh, Vaibhav Shah, Conall McGuinness, Andrew Wong, Anupriya Aggarwal, Michael W Parker, David A Jacques, Stuart Turville, Till Boecking
Kinetics of HIV-1 capsid uncoating revealed by single-molecule analysis. eLife 7 (2018)
Sophie E Broughton, Timothy R Hercus, Tracy L Nero, Winnie L Kan, Emma F Barry, Mara Dottore, Karen S Cheung Tung Shing, Craig J Morton, Urmi Dhagat, Matthew P Hardy, Nicholas J Wilson, Matthew T Downton, Christine Schieber, Timothy P Hughes, Angel F Lopez, Michael W Parker
A dual role for the N-terminal domain of the IL-3 receptor in cell signalling. Nature communications 9 (1) (2018)
Urmi Dhagat, Timothy R Hercus, Sophie E Broughton, Tracy L Nero, Karen S Cheung Tung Shing, Emma F Barry, Christy A Thomson, Steve Bryson, Emil F Pai, Barbara J McClure, John W Schrader, Angel F Lopez, Michael W Parker
The mechanism of GM-CSF inhibition by human GM-CSF auto-antibodies suggests novel therapeutic opportunities. mAbs 10 (7) (2018)
Susan E Northfield, Jerome Wielens, Stephen J Headey, Billy J Williams-Noonan, Mark Mulcair, Martin G Scanlon, Michael W Parker, Philip E Thompson, David K Chalmers
Cyclic Hexapeptide Mimics of the LEDGF Integrase Recognition Loop in Complex with HIV-1 Integrase. ChemMedChem 13 (15) (2018)
Michelle P Christie, Bronte A Johnstone, Rodney K Tweten, Michael W Parker, Craig J Morton
Cholesterol-dependent cytolysins: from water-soluble state to membrane pore. Biophysical reviews 10 (5) (2018)
Denis Tvorogov, Daniel Thomas, Nicholas P D Liau, Mara Dottore, Emma F Barry, Maya Lathi, Winnie L Kan, Timothy R Hercus, Frank Stomski, Timothy P Hughes, Vinay Tergaonkar, Michael W Parker, David Morrall Ross, Ravindra Majeti, Jeffrey J Babon, Angel F Lopez
Accumulation of JAK activation loop phosphorylation is linked to type I JAK inhibitor withdrawal syndrome in myelofibrosis. Science advances 4 (11) (2018)
David Braig, Tracy L Nero, Hans-Georg Koch, Benedict Kaiser, Xiaowei Wang, Jan R Thiele, Craig J Morton, Johannes Zeller, Jurij Kiefer, Lawrence A Potempa, Natalie A Mellett, Luke A Miles, Xiao-Jun Du, Peter J Meikle, Markus Huber-Lang, G Björn Stark, Michael W Parker, Karlheinz Peter, Steffen U Eisenhardt
Transitional changes in the CRP structure lead to the exposure of proinflammatory binding sites. Nature communications 8 (2017)
Michael W Parker, Alessio Bocedi, David B Ascher, Jade B Aitken, Hugh H Harris, Mario Lo Bello, Giorgio Ricci, Craig J Morton, Michael W Parker
Glutathione transferase P1-1 as an arsenic drug-sequestering enzyme. Protein science : a publication of the Protein Society 26 (2) (2016)
Ueli Nachbur, Che A Stafford, Aleksandra Bankovacki, Yifan Zhan, Lisa M Lindqvist, Berthe K Fiil, Yelena Khakham, Hyun-Ja Ko, Jarrod J Sandow, Hendrik Falk, Jessica K Holien, Diep Chau, Joanne Hildebrand, James E Vince, Phillip P Sharp, Andrew I Webb, Katherine A Jackman, Sabrina Mühlen, Catherine L Kennedy, Kym N Lowes, James M Murphy, Mads Gyrd-Hansen, Michael W Parker, Elizabeth L Hartland, Andrew M Lew, David C S Huang, Guillaume Lessene, John Silke
A RIPK2 inhibitor delays NOD signalling events yet prevents inflammatory cytokine production. Nature communications 6 (2015)