Angela M Gronenborn

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 60

Top Venues

Journal of the American Chemical Society

Protein science : a publication of the Protein Society

The journal of physical chemistry. B

Nature communications

University of Pittsburgh

This page only lists publications with an associated author ORCID identifier.

Affiliation History

University of Pittsburgh

United States

UPMC Rosalind Franklin Professor and Chair :: Structural Biology

Publications

Alex J Guseman, Jeremy J González, Darian T Yang, Angela M Gronenborn
Cumulative asparagine to aspartate deamidation fails to perturb γD-crystallin structure and stability. Protein science : a publication of the Protein Society 33 (8) (2024)
Alexey V Bogdanov, Veronica Frydman, Manas Seal, Leonid Rapatskiy, Alexander Schnegg, Wenkai Zhu, Mark A Iron, Angela M Gronenborn, Daniella Goldfarb
Extending the Range of Distances Accessible by 19 F Electron-Nuclear Double Resonance in Proteins Using High-Spin Gd(III) Labels. Journal of the American Chemical Society 146 (9) (2024)
Alex J Guseman, Jeremy J González, Darian T Yang, Angela M Gronenborn
Cumulative asparagine to aspartate deamidation fails to perturb γD-crystallin structure and stability. Protein science : a publication of the Protein Society 33 (8) (2024)
Roza Kalabekova, Caitlin M Quinn, Kumar Tekwani Movellan, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
19 F Fast Magic-Angle Spinning NMR Spectroscopy on Microcrystalline Complexes of Fluorinated Ligands and the Carbohydrate Recognition Domain of Galectin-3. Biochemistry (2024)
Alexey V Bogdanov, Veronica Frydman, Manas Seal, Leonid Rapatskiy, Alexander Schnegg, Wenkai Zhu, Mark A Iron, Angela M Gronenborn, Daniella Goldfarb
Extending the Range of Distances Accessible by 19 F Electron-Nuclear Double Resonance in Proteins Using High-Spin Gd(III) Labels. Journal of the American Chemical Society 146 (9) (2024)
Alex J Guseman, Jeremy J González, Darian T Yang, Angela M Gronenborn
Cumulative asparagine to aspartate deamidation fails to perturb γD-crystallin structure and stability. Protein science : a publication of the Protein Society 33 (8) (2024)
Troy C Krzysiak, You-Jin Choi, Yong Joon Kim, Yunhan Yang, Christopher DeHaven, Lariah Thompson, Ryan Ponticelli, Mara M Mermigos, Laurel Thomas, Andrea Marquez, Ian Sipula, Jongsook Kim Kemper, Michael Jurczak, Gary Thomas, Angela M Gronenborn
Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification. Protein science : a publication of the Protein Society 33 (4) (2024)
Troy C Krzysiak, You-Jin Choi, Yong Joon Kim, Yunhan Yang, Christopher DeHaven, Lariah Thompson, Ryan Ponticelli, Mara M Mermigos, Laurel Thomas, Andrea Marquez, Ian Sipula, Jongsook Kim Kemper, Michael Jurczak, Gary Thomas, Angela M Gronenborn
Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification. Protein science : a publication of the Protein Society 33 (4) (2024)
Alexey V Bogdanov, Veronica Frydman, Manas Seal, Leonid Rapatskiy, Alexander Schnegg, Wenkai Zhu, Mark A Iron, Angela M Gronenborn, Daniella Goldfarb
Extending the Range of Distances Accessible by 19 F Electron-Nuclear Double Resonance in Proteins Using High-Spin Gd(III) Labels. Journal of the American Chemical Society 146 (9) (2024)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis. Protein science : a publication of the Protein Society 33 (3) (2024)
Roza Kalabekova, Caitlin M Quinn, Kumar Tekwani Movellan, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
19 F Fast Magic-Angle Spinning NMR Spectroscopy on Microcrystalline Complexes of Fluorinated Ligands and the Carbohydrate Recognition Domain of Galectin-3. Biochemistry 63 (17) (2024)
Alexey V Bogdanov, Veronica Frydman, Manas Seal, Leonid Rapatskiy, Alexander Schnegg, Wenkai Zhu, Mark A Iron, Angela M Gronenborn, Daniella Goldfarb
Extending the Range of Distances Accessible by 19 F Electron-Nuclear Double Resonance in Proteins Using High-Spin Gd(III) Labels. Journal of the American Chemical Society 146 (9) (2024)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis. Protein science : a publication of the Protein Society 33 (3) (2024)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis. Protein science : a publication of the Protein Society 33 (3) (2024)
Troy C Krzysiak, You-Jin Choi, Yong Joon Kim, Yunhan Yang, Christopher DeHaven, Lariah Thompson, Ryan Ponticelli, Mara M Mermigos, Laurel Thomas, Andrea Marquez, Ian Sipula, Jongsook Kim Kemper, Michael Jurczak, Gary Thomas, Angela M Gronenborn
Inhibitory protein-protein interactions of the SIRT1 deacetylase are choreographed by post-translational modification. Protein science : a publication of the Protein Society 33 (4) (2024)
Alexey V Bogdanov, Veronica Frydman, Manas Seal, Leonid Rapatskiy, Alexander Schnegg, Wenkai Zhu, Mark A Iron, Angela M Gronenborn, Daniella Goldfarb
Extending the Range of Distances Accessible by 19 F Electron-Nuclear Double Resonance in Proteins Using High-Spin Gd(III) Labels. Journal of the American Chemical Society 146 (9) (2024)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis. Protein science : a publication of the Protein Society 33 (3) (2024)
Alexey V Bogdanov, Veronica Frydman, Manas Seal, Leonid Rapatskiy, Alexander Schnegg, Wenkai Zhu, Mark A Iron, Angela M Gronenborn, Daniella Goldfarb
Extending the Range of Distances Accessible by 19 F Electron-Nuclear Double Resonance in Proteins Using High-Spin Gd(III) Labels. Journal of the American Chemical Society (2024)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing effects of site-specific aspartic acid isomerization on structure and stability of GB1 through chemical protein synthesis. Protein science : a publication of the Protein Society 33 (3) (2024)
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex B Kleinpeter, Sherimay Ablan, Hamed Meshkin, Juan R Perilla, Eric O Freed, Barbie K Ganser-Pornillos, Owen Pornillos, Angela M Gronenborn, Tatyana Polenova
Structural basis of HIV-1 maturation inhibitor binding and activity. Nature communications 14 (1) (2023)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing Effects of Site-Specific Aspartic Acid Isomerization on Structure and Stability of GB1 through Chemical Protein Synthesis. Protein science : a publication of the Protein Society (2023)
Xiao-Chen Bai, Tamir Gonen, Angela M Gronenborn, Anastassis Perrakis, Andrea Thorn, Jianyi Yang
Challenges and opportunities in macromolecular structure determination. Nature reviews. Molecular cell biology (2023)
Alex J Guseman, Linda J Rennick, Sham Nambulli, Chandra N Roy, David R Martinez, Darian T Yang, Fatema Bhinderwala, Sandra Vergara, Alexandra Schaefer, Ralph S Baric, Zandrea Ambrose, W Paul Duprex, Angela M Gronenborn
Targeting spike glycans to inhibit SARS-CoV2 viral entry. Proceedings of the National Academy of Sciences of the United States of America 120 (38) (2023)
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex B Kleinpeter, Sherimay Ablan, Hamed Meshkin, Juan R Perilla, Eric O Freed, Barbie K Ganser-Pornillos, Owen Pornillos, Angela M Gronenborn, Tatyana Polenova
Structural basis of HIV-1 maturation inhibitor binding and activity. Nature communications 14 (1) (2023)
Wenkai Zhu, Darian T Yang, Angela M Gronenborn
Ligand-Capped Cobalt(II) Multiplies the Value of the Double-Histidine Motif for PCS NMR Studies. Journal of the American Chemical Society 145 (8) (2023)
Wenkai Zhu, Darian T Yang, Angela M Gronenborn
Ligand-Capped Cobalt(II) Multiplies the Value of the Double-Histidine Motif for PCS NMR Studies. Journal of the American Chemical Society 145 (8) (2023)
Wenkai Zhu, Darian T Yang, Angela M Gronenborn
Ligand-Capped Cobalt(II) Multiplies the Value of the Double-Histidine Motif for PCS NMR Studies. Journal of the American Chemical Society 145 (8) (2023)
Sucharita Sarkar, Kaneil K Zadrozny, Roman Zadorozhnyi, Ryan W Russell, Caitlin M Quinn, Alex B Kleinpeter, Sherimay Ablan, Hamed Meshkin, Juan R Perilla, Eric O Freed, Barbie K Ganser-Pornillos, Owen Pornillos, Angela M Gronenborn, Tatyana Polenova
Structural basis of HIV-1 maturation inhibitor binding and activity. Nature communications 14 (1) (2023)
Wenkai Zhu, Darian T Yang, Angela M Gronenborn
Ligand-Capped Cobalt(II) Multiplies the Value of the Double-Histidine Motif for PCS NMR Studies. Journal of the American Chemical Society (2023)
Shelby L Heath, Alex J Guseman, Angela M Gronenborn, W Seth Horne
Probing Effects of Site-Specific Aspartic Acid Isomerization on Structure and Stability of GB1 through Chemical Protein Synthesis. Protein science : a publication of the Protein Society (2023)
Chunting Zhang, Changmiao Guo, Ryan W Russell, Caitlin M Quinn, Mingyue Li, John C Williams, Angela M Gronenborn, Tatyana Polenova
Magic-angle-spinning NMR structure of the kinesin-1 motor domain assembled with microtubules reveals the elusive neck linker orientation. Nature communications 13 (1) (2022)
Sucharita Sarkar, Brent Runge, Ryan W Russell, Kumar Tekwani Movellan, Daniel Calero, Somayeh Zeinalilathori, Caitlin M Quinn, Manman Lu, Guillermo Calero, Angela M Gronenborn, Tatyana Polenova
Atomic-Resolution Structure of SARS-CoV-2 Nucleocapsid Protein N-Terminal Domain. Journal of the American Chemical Society 144 (23) (2022)
Angela M Gronenborn, Tatyana Polenova
Introduction: Biomolecular NMR Spectroscopy. Chemical reviews 122 (10) (2022)
Wenkai Zhu, Alex J Guseman, Fatema Bhinderwala, Manman Lu, Xun-Cheng Su, Angela M Gronenborn
Visualizing Proteins in Mammalian Cells by 19 F NMR Spectroscopy. Angewandte Chemie (International ed. in English) 61 (23) (2022)
Darian T Yang, Angela M Gronenborn, Lillian T Chong
Development and Validation of Fluorinated, Aromatic Amino Acid Parameters for Use with the AMBER ff15ipq Protein Force Field. The journal of physical chemistry. A 126 (14) (2022)
Manman Lu, Dmitri Toptygin, Yufei Xiang, Yi Shi, Charles D Schwieters, Emma C Lipinski, Jinwoo Ahn, In-Ja L Byeon, Angela M Gronenborn
The Magic of Linking Rings: Discovery of a Unique Photoinduced Fluorescent Protein Crosslink. Journal of the American Chemical Society 144 (24) (2022)
In-Ja L Byeon, Guillermo Calero, Ying Wu, Chang Hyeock Byeon, Jinwon Jung, Maria DeLucia, Xiaohong Zhou, Simon Weiss, Jinwoo Ahn, Caili Hao, Jacek Skowronski, Angela M Gronenborn
Structure of HIV-1 Vpr in complex with the human nucleotide excision repair protein hHR23A. Nature communications 12 (1) (2021)
Caitlin M Quinn, Roman Zadorozhnyi, Jochem Struppe, Ivan V Sergeyev, Angela M Gronenborn, Tatyana Polenova
Fast 19F Magic-Angle Spinning Nuclear Magnetic Resonance for the Structural Characterization of Active Pharmaceutical Ingredients in Blockbuster Drugs. Analytical chemistry 93 (38) (2021)
Changmiao Guo, Matthew P Fritz, Jochem Struppe, Sebastian Wegner, John Stringer, Ivan V Sergeyev, Caitlin M Quinn, Angela M Gronenborn, Tatyana Polenova
Fast 19F Magic Angle Spinning NMR Crystallography for Structural Characterization of Fluorine-Containing Pharmaceutical Compounds. Analytical chemistry 93 (23) (2021)
Jochem Struppe, Caitlin M Quinn, Sucharita Sarkar, Angela M Gronenborn, Tatyana Polenova
Ultrafast 1H MAS NMR Crystallography for Natural Abundance Pharmaceutical Compounds. Molecular pharmaceutics 17 (2) (2020)
Jodi Kraus, Rupal Gupta, Manman Lu, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
Accurate Backbone 13 C and 15 N Chemical Shift Tensors in Galectin-3 Determined by MAS NMR and QM/MM: Details of Structure and Environment Matter. Chemphyschem : a European journal of chemical physics and physical chemistry 21 (13) (2020)
Manman Lu, Ryan W Russell, Alexander J Bryer, Caitlin M Quinn, Guang-Jin Hou, Huilan Zhang, Charles D Schwieters, Juan R Perilla, Angela M Gronenborn, Tatyana Polenova
Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR. Nature structural & molecular biology 27 (9) (2020)
Manman Lu, Rieko Ishima, Tatyana Polenova, Angela M Gronenborn
19F NMR relaxation studies of fluorosubstituted tryptophans. Journal of biomolecular NMR 73 (8-9) (2019)
Angela M Gronenborn
Integrated multidisciplinarity in the natural sciences. The Journal of biological chemistry 294 (48) (2019)
Rupal Gupta, Huilan Zhang, Manman Lu, Guang-Jin Hou, Marc Caporini, Melanie Rosay, Werner Maas, Jochem Struppe, Jinwoo Ahn, In-Ja L Byeon, Hartmut Oschkinat, Kristaps Jaudzems, Emeline Barbet-Massin, Lyndon Emsley, Guido Pintacuda, Anne Lesage, Angela M Gronenborn, Tatyana Polenova
Dynamic Nuclear Polarization Magic-Angle Spinning Nuclear Magnetic Resonance Combined with Molecular Dynamics Simulations Permits Detection of Order and Disorder in Viral Assemblies. The journal of physical chemistry. B 123 (24) (2019)
Matthew Fritz, Jodi Kraus, Caitlin M Quinn, Glenn P A Yap, Jochem Struppe, Ivan V Sergeyev, Angela M Gronenborn, Tatyana Polenova
Measurement of Accurate Interfluorine Distances in Crystalline Organic Solids: A High-Frequency Magic Angle Spinning NMR Approach. The journal of physical chemistry. B 123 (50) (2019)
Karl T Debiec, Angela M Gronenborn, Lillian T Chong
Correction to "Evaluating the Strength of Salt Bridges: A Comparison of Current Biomolecular Force Fields". The journal of physical chemistry. B 123 (19) (2019)
Esra Bozkurt, Angela M Gronenborn
Diversifying Constrained Peptide Scaffolds: How To Truss Up a Bundle Really Tight. Biochemistry 58 (9) (2019)
Alex J Guseman, Angela M Gronenborn
Isomerization as the secret Achilles' heel of long-lived proteins. The Journal of biological chemistry 294 (19) (2019)
Manman Lu, Mingzhang Wang, Ivan V Sergeyev, Caitlin M Quinn, Jochem Struppe, Melanie Rosay, Werner Maas, Angela M Gronenborn, Tatyana Polenova
19F Dynamic Nuclear Polarization at Fast Magic Angle Spinning for NMR of HIV-1 Capsid Protein Assemblies. Journal of the American Chemical Society 141 (14) (2019)
Caitlin M Quinn, Mingzhang Wang, Matthew P Fritz, Brent Runge, Jinwoo Ahn, Chaoyi Xu, Juan R Perilla, Angela M Gronenborn, Tatyana Polenova
Dynamic regulation of HIV-1 capsid interaction with the restriction factor TRIM5α identified by magic-angle spinning NMR and molecular dynamics simulations. Proceedings of the National Academy of Sciences of the United States of America 115 (45) (2018)
Manman Lu, Sucharita Sarkar, Mingzhang Wang, Jodi Kraus, Matthew Fritz, Caitlin M Quinn, Shi Bai, Sean T Holmes, Cecil Dybowski, Glenn P A Yap, Jochem Struppe, Ivan V Sergeyev, Werner Maas, Angela M Gronenborn, Tatyana Polenova
19F Magic Angle Spinning NMR Spectroscopy and Density Functional Theory Calculations of Fluorosubstituted Tryptophans: Integrating Experiment and Theory for Accurate Determination of Chemical Shift Tensors. The journal of physical chemistry. B 122 (23) (2018)
Mingzhang Wang, Manman Lu, Matthew P Fritz, Caitlin M Quinn, In-Ja L Byeon, Chang Hyeock Byeon, Jochem Struppe, Werner Maas, Angela M Gronenborn, Tatyana Polenova
Fast Magic-Angle Spinning 19 F NMR Spectroscopy of HIV-1 Capsid Protein Assemblies. Angewandte Chemie (International ed. in English) 57 (50) (2018)
Jodi Kraus, Rupal Gupta, Jenna Yehl, Manman Lu, David A Case, Angela M Gronenborn, Mikael Akke, Tatyana Polenova
Chemical Shifts of the Carbohydrate Binding Domain of Galectin-3 from Magic Angle Spinning NMR and Hybrid Quantum Mechanics/Molecular Mechanics Calculations. The journal of physical chemistry. B 122 (11) (2018)
Gustav Nestor, Taigh Anderson, Stefan Oscarson, Angela M Gronenborn
Exploiting Uniformly 13C-Labeled Carbohydrates for Probing Carbohydrate-Protein Interactions by NMR Spectroscopy. Journal of the American Chemical Society 139 (17) (2017)
Juan R Perilla, Gongpu Zhao, Manman Lu, Jiying Ning, Guangjin Hou, In-Ja L Byeon, Angela M Gronenborn, Tatyana Polenova, Peijun Zhang
CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations. The journal of physical chemistry. B 121 (15) (2017)
Gustav Nestor, Taigh Anderson, Stefan Oscarson, Angela M Gronenborn
Direct Observation of Carbohydrate Hydroxyl Protons in Hydrogen Bonds with a Protein. Journal of the American Chemical Society 140 (1) (2017)
Naima G Sharaf, Zhaoyong Xi, Rieko Ishima, Angela M Gronenborn
The HIV-1 p66 homodimeric RT exhibits different conformations in the binding-competent and -incompetent NNRTI site. Proteins 85 (12) (2017)
Matthew Fritz, Caitlin M Quinn, Mingzhang Wang, Guangjin Hou, Xingyu Lu, Leonardus M I Koharudin, Tatyana Polenova, Angela M Gronenborn
Toward Closing the Gap: Quantum Mechanical Calculations and Experimentally Measured Chemical Shifts of a Microcrystalline Lectin. The journal of physical chemistry. B 121 (15) (2016)
Naima G Sharaf, Andrew E Brereton, In-Ja L Byeon, P Andrew Karplus, Angela M Gronenborn
NMR structure of the HIV-1 reverse transcriptase thumb subdomain. Journal of biomolecular NMR 66 (4) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Angela M Gronenborn