Julien Prudent

Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2020-2024
Publications (10 Years): 42

Top Topics

Induced Apoptosis

Endoplasmic Reticulum

Top Venues

Nature communications

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Emma Louise Wilson, Yizhou Yu, Nuno S Leal, James A Woodward, Nikolaos Patikas, Jordan L Morris, Sarah F Field, William Plumbly, Vincent Paupe, Suvagata R Chowdhury, Robin Antrobus, Georgina E Lindop, Yusuf M Adia, Samantha H Y Loh, Julien Prudent, Luis Miguel Martins, Emmanouil Metzakopian
Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective. Cell death & disease 15 (3) (2024)
Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, David Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, Tommy L Lewis
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nature communications 15 (1) (2024)
Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, David Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, Tommy L Lewis
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nature communications 15 (1) (2024)
Karinder K Brar, Daniel T Hughes, Jordan L Morris, Kelly Subramanian, Shivaani Krishna, Fei Gao, Lara-Sophie Rieder, Sebastian Uhrig, Joshua Freeman, Heather L Smith, Rebekkah Jukes-Jones, Edward Avezov, Jodi Nunnari, Julien Prudent, Adrian J Butcher, Giovanna R Mallucci
PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress. Science (New York, N.Y.) 385 (6712) (2024)
Emma Louise Wilson, Yizhou Yu, Nuno S Leal, James A Woodward, Nikolaos Patikas, Jordan L Morris, Sarah F Field, William Plumbly, Vincent Paupe, Suvagata R Chowdhury, Robin Antrobus, Georgina E Lindop, Yusuf M Adia, Samantha H Y Loh, Julien Prudent, Luis Miguel Martins, Emmanouil Metzakopian
Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective. Cell death & disease 15 (3) (2024)
Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, David Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, Tommy L Lewis
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nature communications 15 (1) (2024)
Karinder K Brar, Daniel T Hughes, Jordan L Morris, Kelly Subramanian, Shivaani Krishna, Fei Gao, Lara-Sophie Rieder, Sebastian Uhrig, Joshua Freeman, Heather L Smith, Rebekkah Jukes-Jones, Edward Avezov, Jodi Nunnari, Julien Prudent, Adrian J Butcher, Giovanna R Mallucci
PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress. Science (New York, N.Y.) 385 (6712) (2024)
Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, David Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, Tommy L Lewis
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nature communications 15 (1) (2024)
Emma Louise Wilson, Yizhou Yu, Nuno S Leal, James A Woodward, Nikolaos Patikas, Jordan L Morris, Sarah F Field, William Plumbly, Vincent Paupe, Suvagata R Chowdhury, Robin Antrobus, Georgina E Lindop, Yusuf M Adia, Samantha H Y Loh, Julien Prudent, Luis Miguel Martins, Emmanouil Metzakopian
Genome-wide CRISPR/Cas9 screen shows that loss of GET4 increases mitochondria-endoplasmic reticulum contact sites and is neuroprotective. Cell death & disease 15 (3) (2024)
Karinder K Brar, Daniel T Hughes, Jordan L Morris, Kelly Subramanian, Shivaani Krishna, Fei Gao, Lara-Sophie Rieder, Sebastian Uhrig, Joshua Freeman, Heather L Smith, Rebekkah Jukes-Jones, Edward Avezov, Jodi Nunnari, Julien Prudent, Adrian J Butcher, Giovanna R Mallucci
PERK-ATAD3A interaction provides a subcellular safe haven for protein synthesis during ER stress. Science (New York, N.Y.) (2024)
Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, David Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, Tommy L Lewis
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nature communications 15 (1) (2024)
Daniel M Virga, Stevie Hamilton, Bertha Osei, Abigail Morgan, Parker Kneis, Emiliano Zamponi, Natalie J Park, Victoria L Hewitt, David Zhang, Kevin C Gonzalez, Fiona M Russell, David Grahame Hardie, Julien Prudent, Erik B Bloss, Attila Losonczy, Franck Polleux, Tommy L Lewis
Activity-dependent compartmentalization of dendritic mitochondria morphology through local regulation of fusion-fission balance in neurons in vivo. Nature communications 15 (1) (2024)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin 2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Yibo Xue, Jordan L Morris, Kangning Yang, Zheng Fu, Xianbing Zhu, Fraser Johnson, Brian Meehan, Leora Witkowski, Amber Yasmeen, Tunde Golenar, Mackenzie Coatham, Geneviève Morin, Anie Monast, Virginie Pilon, Pierre Olivier Fiset, Sungmi Jung, Anne V Gonzalez, Sophie Camilleri-Broët, Lili Fu, Lynne-Marie Postovit, Jonathan D Spicer, Walter H Gotlieb, Marie-Christine Guiot, Janusz Rak, Morag Park, William W Lockwood, William D Foulkes, Julien Prudent, Sidong Huang
Author Correction: SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca 2+ flux to mitochondria. Nature communications 14 (1) (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, LuisCa C Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin 2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature 615 (7952) (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Yibo Xue, Jordan L Morris, Kangning Yang, Zheng Fu, Xianbing Zhu, Fraser Johnson, Brian Meehan, Leora Witkowski, Amber Yasmeen, Tunde Golenar, Mackenzie Coatham, Geneviève Morin, Anie Monast, Virginie Pilon, Pierre Olivier Fiset, Sungmi Jung, Anne V Gonzalez, Sophie Camilleri-Broët, Lili Fu, Lynne-Marie Postovit, Jonathan D Spicer, Walter H Gotlieb, Marie-Christine Guiot, Janusz Rak, Morag Park, William W Lockwood, William D Foulkes, Julien Prudent, Sidong Huang
Author Correction: SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca 2+ flux to mitochondria. Nature communications 14 (1) (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin 2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature 615 (7952) (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature 615 (7952) (2023)
Jake Peter Mann, Xiaowen Duan, Satish Patel, Luis Carlos Tábara, Fabio Scurria, Anna Alvarez-Guaita, Afreen Haider, Ineke Luijten, Matthew Page, Margherita Protasoni, Koini Lim, Samuel Virtue, Stephen I O'Rahilly, Martin Armstrong, Julien Prudent, Robert K Semple, David B Savage
A mouse model of human mitofusin-2-related lipodystrophy exhibits adipose-specific mitochondrial stress and reduced leptin secretion. eLife 12 (2023)
Vincent Zecchini, Vincent Paupe, Irene Herranz-Montoya, Joëlle Janssen, Inge M N Wortel, Jordan L Morris, Ashley Ferguson, Suvagata Roy Chowdury, Marc Segarra-Mondejar, Ana S H Costa, Gonçalo C Pereira, Laura Tronci, Timothy Young, Efterpi Nikitopoulou, Ming Yang, Dóra Bihary, Federico Caicci, Shun Nagashima, Alyson Speed, Kalliopi Bokea, Zara Baig, Shamith A Samarajiwa, Maxine Tran, Thomas J Mitchell, Mark Johnson, Julien Prudent, Christian Frezza
Fumarate induces vesicular release of mtDNA to drive innate immunity. Nature 615 (7952) (2023)
Luis Carlos Tábara, Fatema Al-Salmi, Reza Maroofian, Amna Mohammed Al-Futaisi, Fathiya Al-Murshedi, Joanna Kennedy, Jacob O Day, Thomas Courtin, Aisha Al-Khayat, Hamid Galedari, Neda Mazaheri, Margherita Protasoni, Mark Johnson, Joseph S Leslie, Claire G Salter, Lettie E Rawlins, James Fasham, Almundher Al-Maawali, Nikol Voutsina, Perrine Charles, Laura Harrold, Boris Keren, Edmund R S Kunji, Barbara Vona, Gholamreza Jelodar, Alireza Sedaghat, Gholamreza Shariati, Henry Houlden, Andrew H Crosby, Julien Prudent, Emma L Baple
TMEM63C mutations cause mitochondrial morphology defects and underlie hereditary spastic paraplegia. Brain : a journal of neurology 145 (9) (2022)
Victoria L Hewitt, Leonor Miller-Fleming, Madeleine J Twyning, Simonetta Andreazza, Francesca Mattedi, Julien Prudent, Franck Polleux, Alessio Vagnoni, Alexander J Whitworth
Decreasing pdzd8-mediated mito-ER contacts improves organismal fitness and mitigates Aβ 42 toxicity. Life science alliance 5 (11) (2022)
Lisa Tilokani, Fiona M Russell, Stevie Hamilton, Daniel M Virga, Mayuko Segawa, Vincent Paupe, Anja V Gruszczyk, Margherita Protasoni, Luis-Carlos Tabara, Mark Johnson, Hanish Anand, Michael P Murphy, David Grahame Hardie, Franck Polleux, Julien Prudent
AMPK-dependent phosphorylation of MTFR1L regulates mitochondrial morphology. Science advances 8 (45) (2022)
Yibo Xue, Jordan L Morris, Kangning Yang, Zheng Fu, Xianbing Zhu, Fraser Johnson, Brian Meehan, Leora Witkowski, Amber Yasmeen, Tunde Golenar, Mackenzie Coatham, Geneviève Morin, Anie Monast, Virginie Pilon, Pierre Olivier Fiset, Sungmi Jung, Anne V Gonzalez, Sophie Camilleri-Broët, Lili Fu, Lynne-Marie Postovit, Jonathan D Spicer, Walter H Gotlieb, Marie-Christine Guiot, Janusz Rak, Morag Park, William W Lockwood, William D Foulkes, Julien Prudent, Sidong Huang
SMARCA4/2 loss inhibits chemotherapy-induced apoptosis by restricting IP3R3-mediated Ca2+ flux to mitochondria. Nature communications 12 (1) (2021)
Mikael G Pezet, Aurora Gomez-Duran, Florian Klimm, Juvid Aryaman, Stephen Burr, Wei Wei, Mitinori Saitou, Julien Prudent, Patrick F Chinnery
Oxygen tension modulates the mitochondrial genetic bottleneck and influences the segregation of a heteroplasmic mtDNA variant in vitro. Communications biology 4 (1) (2021)
Miriam Lisci, Philippa R Barton, Lyra O Randzavola, Claire Y Ma, Julia M Marchingo, Doreen A Cantrell, Vincent Paupe, Julien Prudent, Jane C Stinchcombe, Gillian M Griffiths
Mitochondrial translation is required for sustained killing by cytotoxic T cells. Science (New York, N.Y.) 374 (6565) (2021)
Hope I Needs, Margherita Protasoni, Jeremy M Henley, Julien Prudent, Ian Collinson, Gonçalo C Pereira
Interplay between Mitochondrial Protein Import and Respiratory Complexes Assembly in Neuronal Health and Degeneration. Life (Basel, Switzerland) 11 (5) (2021)
Jordan L Morris, Germain Gillet, Julien Prudent, Nikolay Popgeorgiev
Bcl-2 Family of Proteins in the Control of Mitochondrial Calcium Signalling: An Old Chap with New Roles. International journal of molecular sciences 22 (7) (2021)
Shun Nagashima, Luis-Carlos Tábara, Lisa Tilokani, Vincent Paupe, Hanish Anand, Joe H Pogson, Rodolfo Zunino, Heidi M McBride, Julien Prudent
Golgi-derived PI(4)P-containing vesicles drive late steps of mitochondrial division. Science (New York, N.Y.) 367 (6484) (2020)