Karen K Hirschi (Karen Hirschi)

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Topics

Vascular Endothelial Growth Factor

Neural Stem Cells

Cell Proliferation

Top Venues

Nature communications

Life science alliance

Nature cardiovascular research

This page only lists publications with an associated author ORCID identifier.

Publications

Keita Horitani, Nicholas W Chavkin, Yohei Arai, Ying Wang, Hayato Ogawa, Yoshimitsu Yura, Megan A Evans, Jesse D Cochran, Mark Charles Thel, Ariel H Polizio, Miho Sano, Emiri Miura-Yura, Yuka Arai, Heather Doviak, Arthur P Arnold, Bradley D Gelfand, Karen K Hirschi, Soichi Sano, Kenneth Walsh
Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure. Nature cardiovascular research 3 (3) (2024)
Keita Horitani, Nicholas W Chavkin, Yohei Arai, Ying Wang, Hayato Ogawa, Yoshimitsu Yura, Megan A Evans, Jesse D Cochran, Mark Charles Thel, Ariel H Polizio, Miho Sano, Emiri Miura-Yura, Yuka Arai, Heather Doviak, Arthur P Arnold, Bradley D Gelfand, Karen K Hirschi, Soichi Sano, Kenneth Walsh
Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure. Nature cardiovascular research 3 (3) (2024)
Keita Horitani, Nicholas W Chavkin, Yohei Arai, Ying Wang, Hayato Ogawa, Yoshimitsu Yura, Megan A Evans, Jesse D Cochran, Mark Charles Thel, Ariel H Polizio, Miho Sano, Emiri Miura-Yura, Yuka Arai, Heather Doviak, Arthur P Arnold, Bradley D Gelfand, Karen K Hirschi, Soichi Sano, Kenneth Walsh
Disruption of the Uty epigenetic regulator locus in hematopoietic cells phenocopies the profibrotic attributes of Y chromosome loss in heart failure. Nature cardiovascular research 3 (3) (2024)
Gael Genet, Nafiisha Genet, Umadevi Paila, Shelby R Cain, Aleksandra Cwiek, Nicholas W Chavkin, Vlad Serbulea, Agnès Figueras, Pau Cerdà, Stephanie P McDonnell, Danya Sankaranarayanan, Mahalia Huba, Elizabeth A Nelson, Antoni Riera-Mestre, Karen K Hirschi
Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation 149 (12) (2023)
Gael Genet, Nafiisha Genet, Umadevi Paila, Shelby R Cain, Aleksandra Cwiek, Nicholas W Chavkin, Vlad Serbulea, Agnès Figueras, Pau Cerdà, Stephanie P McDonnell, Danya Sankaranarayanan, Mahalia Huba, Elizabeth A Nelson, Antoni Riera-Mestre, Karen K Hirschi
Induced Endothelial Cell CycleArrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation (2023)
Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi
Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life science alliance 6 (8) (2023)
Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi
Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life science alliance 6 (8) (2023)
Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi
Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life science alliance 6 (8) (2023)
Gael Genet, Nafiisha Genet, Umadevi Paila, Shelby R Cain, Aleksandra Cwiek, Nicholas W Chavkin, Vlad Serbulea, Agnès Figueras, Pau Cerdà, Stephanie P McDonnell, Danya Sankaranarayanan, Mahalia Huba, Elizabeth A Nelson, Antoni Riera-Mestre, Karen K Hirschi
Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation 149 (12) (2023)
Jesse D Cochran, Yoshimitsu Yura, Mark Charles Thel, Heather Doviak, Ariel H Polizio, Yuka Arai, Yohei Arai, Keita Horitani, Eunbee Park, Nicholas W Chavkin, Anupreet Kour, Soichi Sano, Nitin Mahajan, Megan A Evans, Mahalia Huba, Nadia Martinez Naya, Hanna Sun, Young Ho Ban, Karen K Hirschi, Stefano Toldo, Antonio Abbate, Todd E Druley, Frederick L Ruberg, Mathew S Maurer, Justin A Ezekowitz, Jason R B Dyck, Kenneth Walsh
Clonal Hematopoiesis in Clinical and Experimental Heart Failure With Preserved Ejection Fraction. Circulation (2023)
Gael Genet, Nafiisha Genet, Umadevi Paila, Shelby R Cain, Aleksandra Cwiek, Nicholas W Chavkin, Vlad Serbulea, Agnès Figueras, Pau Cerdà, Stephanie P McDonnell, Danya Sankaranarayanan, Mahalia Huba, Elizabeth A Nelson, Antoni Riera-Mestre, Karen K Hirschi
Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation 149 (12) (2023)
Bipul R Acharya, Jennifer S Fang, Erin D Jeffery, Nicholas W Chavkin, Gael Genet, Hema Vasavada, Elizabeth A Nelson, Gloria M Sheynkman, Martin J Humphries, Karen K Hirschi
Connexin 37 sequestering of activated-ERK in the cytoplasm promotes p27-mediated endothelial cell cycle arrest. Life science alliance 6 (8) (2023)
Gael Genet, Nafiisha Genet, Umadevi Paila, Shelby R Cain, Aleksandra Cwiek, Nicholas W Chavkin, Vlad Serbulea, Agnès Figueras, Pau Cerdà, Stephanie P McDonnell, Danya Sankaranarayanan, Mahalia Huba, Elizabeth A Nelson, Antoni Riera-Mestre, Karen K Hirschi
Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation 149 (12) (2023)
Gael Genet, Nafiisha Genet, Umadevi Paila, Shelby R Cain, Aleksandra Cwiek, Nicholas W Chavkin, Vlad Serbulea, Agnès Figueras, Pau Cerdà, Stephanie P McDonnell, Danya Sankaranarayanan, Mahalia Huba, Elizabeth A Nelson, Antoni Riera-Mestre, Karen K Hirschi
Induced Endothelial Cell Cycle Arrest Prevents Arteriovenous Malformations in Hereditary Hemorrhagic Telangiectasia. Circulation 149 (12) (2023)
Nicholas W Chavkin, Gael Genet, Mathilde Poulet, Erin D Jeffery, Corina Marziano, Nafiisha Genet, Hema Vasavada, Elizabeth A Nelson, Bipul R Acharya, Anupreet Kour, Jordon Aragon, Stephanie P McDonnell, Mahalia Huba, Gloria M Sheynkman, Kenneth Walsh, Karen K Hirschi
Endothelial cell cycle state determines propensity for arterial-venous fate. Nature communications 13 (1) (2022)
Soichi Sano, Keita Horitani, Hayato Ogawa, Jonatan Halvardson, Nicholas W Chavkin, Ying Wang, Miho Sano, Jonas Mattisson, Atsushi Hata, Marcus Danielsson, Emiri Miura-Yura, Ammar Zaghlool, Megan A Evans, Christoph Nowak, Henry N De Hoyos, Johan Sundström, Yoshimitsu Yura, Anupreet Kour, Yohei Arai, Mark C Thel, Yuka Arai, Josyf C Mychaleckyi, Karen K Hirschi, Lars A Forsberg, Kenneth Walsh
Hematopoietic loss of Y chromosome leads to cardiac fibrosis and heart failure mortality. Science (New York, N.Y.) 377 (6603) (2022)
Kacey Ronaldson-Bouchard, Diogo Teles, Keith Yeager, Daniel Naveed Tavakol, Yimu Zhao, Alan Chramiec, Somnath Tagore, Max Summers, Sophia Stylianos, Manuel Tamargo, Busub Marcus Lee, Susan P Halligan, Erbil Hasan Abaci, Zongyou Guo, Joanna Jacków, Alberto Pappalardo, Jerry Shih, Rajesh K Soni, Shivam Sonar, Carrie German, Angela M Christiano, Andrea Califano, Karen K Hirschi, Christopher S Chen, Andrzej Przekwas, Gordana Vunjak-Novakovic
A multi-organ chip with matured tissue niches linked by vascular flow. Nature biomedical engineering 6 (4) (2022)
Corina Marziano, Gael Genet, Karen K Hirschi
Vascular endothelial cell specification in health and disease. Angiogenesis 24 (2) (2021)
Nafiisha Genet, Karen K Hirschi
Understanding neural stem cell regulation in vivo and applying the insights to cell therapy for strokes. Regenerative medicine 16 (9) (2021)
Rita Matta, Seyoung Lee, Nafiisha Genet, Karen K Hirschi, Jean-Leon Thomas, Anjelica L Gonzalez
Author Correction: Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone. Scientific reports 10 (1) (2020)
Dionna M Kasper, Jared Hintzen, Yinyu Wu, Joey J Ghersi, Hanna K Mandl, Kevin E Salinas, William Armero, Zhiheng He, Ying Sheng, Yixuan Xie, Daniel W Heindel, Eon Joo Park, William C Sessa, Lara K Mahal, Carlito B Lebrilla, Karen K Hirschi, Stefania Nicoli
The N-glycome regulates the endothelial-to-hematopoietic transition. Science (New York, N.Y.) 370 (6521) (2020)
Jennifer Fang, Karen K Hirschi
Molecular regulation of arteriovenous endothelial cell specification. F1000Research 8 (2019)
Rita Matta, Seyoung Lee, Nafiisha Genet, Karen K Hirschi, Jean-Leon Thomas, Anjelica L Gonzalez
Minimally Invasive Delivery of Microbeads with Encapsulated, Viable and Quiescent Neural Stem Cells to the Adult Subventricular Zone. Scientific reports 9 (1) (2019)
Jennifer S Fang, Brian G Coon, Noelle Gillis, Zehua Chen, Jingyao Qiu, Thomas W Chittenden, Janis M Burt, Martin Alexander Schwartz, Karen K Hirschi
Addendum: Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nature communications 9 (1) (2018)
Jennifer S Fang, Brian G Coon, Noelle Gillis, Zehua Chen, Jingyao Qiu, Thomas W Chittenden, Janis M Burt, Martin Alexander Schwartz, Karen K Hirschi
Shear-induced Notch-Cx37-p27 axis arrests endothelial cell cycle to enable arterial specification. Nature communications 8 (1) (2017)
Elisabetta Dejana, Karen K Hirschi, Michael Simons
The molecular basis of endothelial cell plasticity. Nature communications 8 (2017)