Keith W Caldecott (Keith Caldecott)

Publication Activity (10 Years)

Years Active: 2019-2024
Publications (10 Years): 26

Top Topics

Intellectual Disability

Amyotrophic Lateral Sclerosis

Circulating Tumor

Top Venues

The Journal of cell biology

Nature communications

bioRxiv : the preprint server for biology

The EMBO journal

This page only lists publications with an associated author ORCID identifier.

Publications

Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Kristyna Hrychova, Kamila Burdova, Zuzana Polackova, Despoina Giamaki, Beatrice Valtorta, Jan Brazina, Katerina Krejcikova, Barbora Kuttichova, Keith W Caldecott, Hana Hanzlikova
Dispensability of HPF1 for cellular removal of DNA single-strand breaks. Nucleic acids research (2024)
Zita Fábián, Ellen S Kakulidis, Ivo A Hendriks, Ulrike Kühbacher, Nicolai Balle Larsen, Marta Oliva-Santiago, Junhui Wang, Xueyuan Leng, A Barbara Dirac-Svejstrup, Jesper Q Svejstrup, Michael Lund Nielsen, Keith W Caldecott, Julien P Duxin
PARP1-dependent DNA-protein crosslink repair. Nature communications 15 (1) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Zita Fábián, Ellen S Kakulidis, Ivo A Hendriks, Ulrike Kühbacher, Nicolai Balle Larsen, Marta Oliva-Santiago, Junhui Wang, Xueyuan Leng, A Barbara Dirac-Svejstrup, Jesper Q Svejstrup, Michael Lund Nielsen, Keith W Caldecott, Julien P Duxin
PARP1-dependent DNA-protein crosslink repair. Nature communications 15 (1) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA combing versus DNA spreading and the separation of sister chromatids. The Journal of cell biology 223 (4) (2024)
Zita Fábián, Ellen S Kakulidis, Ivo A Hendriks, Ulrike Kühbacher, Nicolai Balle Larsen, Marta Oliva-Santiago, Junhui Wang, Xueyuan Leng, A Barbara Dirac-Svejstrup, Jesper Q Svejstrup, Michael Lund Nielsen, Keith W Caldecott, Julien P Duxin
PARP1-dependent DNA-protein crosslink repair. Nature communications 15 (1) (2024)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA Combing versus DNA Spreading and the Separation of Sister Chromatids. bioRxiv : the preprint server for biology (2023)
Alice Meroni, Sophie E Wells, Carmen Fonseca, Arnab Ray Chaudhuri, Keith W Caldecott, Alessandro Vindigni
DNA Combing versus DNA Spreading and the Separation of Sister Chromatids. bioRxiv : the preprint server for biology (2023)
Almudena Serrano-Benitez, Sophie E Wells, Lylah Drummond-Clarke, Lilian C Russo, John Christopher Thomas, Giovanna A Leal, Mark Farrow, James Michael Edgerton, Shankar Balasubramanian, Ming Yang, Christian Frezza, Amit Gautam, Jan Brazina, Kamila Burdova, Nícolas Carlos Hoch, Stephen P Jackson, Keith W Caldecott
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity. The EMBO journal (2023)
Dongpeng Wang, Wei Wu, Elsa Callen, Raphael S Pavani, Nicholas Zolnerowich, Srikanth Kodali, Dali Zong, Nancy Wong, Santiago Noriega, William J Nathan, Gabriel E Matos-Rodrigues, Raj Chari, Michael J Kruhlak, Ferenc Livak, Michael Emmerson Ward, Keith W Caldecott, Bruno Di Stefano, Andrè Nussenzweig
Active DNA demethylation promotes cell fate specification and the DNA damage response. Science (New York, N.Y.) 378 (6623) (2022)
Zuzana Cihlarova, Jan Kubovciak, Margarita Sobol, Katerina Krejcikova, Jana Sachova, Michal Kolář, David Staněk, Cyril Barinka, Grace Yoon, Keith W Caldecott, Hana Hanzlikova
BRAT1 links Integrator and defective RNA processing with neurodegeneration. Nature communications 13 (1) (2022)
Alina Vaitsiankova, Kamila Burdova, Margarita Sobol, Amit Gautam, Oldřich Benada, Hana Hanzlikova, Keith W Caldecott
PARP inhibition impedes the maturation of nascent DNA strands during DNA replication. Nature structural & molecular biology 29 (4) (2022)
Keith W Caldecott, Michael Emmerson Ward, Andrè Nussenzweig
The threat of programmed DNA damage to neuronal genome integrity and plasticity. Nature genetics 54 (2) (2022)
Wei Wu, Sarah E Kargbo-Hill, William J Nathan, Jacob Paiano, Elsa Callen, Dongpeng Wang, Kenta Shinoda, Niek van Wietmarschen, Jennifer M Colón-Mercado, Dali Zong, Raffaella De Pace, Han-Yu Shih, Steven L Coon, Maia Parsadanian, Raphael Pavani, Hana Hanzlikova, Solji Park, Seol Kyoung Jung, Peter J McHugh, Andres Canela, Chongyi Chen, Rafael Casellas, Keith W Caldecott, Michael Emmerson Ward, Andrè Nussenzweig
Neuronal enhancers are hotspots for DNA single-strand break repair. Nature 593 (7859) (2021)
Emilia Komulainen, Jack Badman, Stephanie Rey, Stuart Rulten, Limei Ju, Kate Fennell, Ilona Kalasova, Kristyna Ilievova, Peter J McKinnon, Hana Hanzlikova, Kevin Staras, Keith W Caldecott
Parp1 hyperactivity couples DNA breaks to aberrant neuronal calcium signalling and lethal seizures. EMBO reports 22 (5) (2021)
Marek Adamowicz, Richard Hailstone, Annie A Demin, Emilia Komulainen, Hana Hanzlikova, Jan Brazina, Amit Gautam, Sophie E Wells, Keith W Caldecott
XRCC1 protects transcription from toxic PARP1 activity during DNA base excision repair. Nature cell biology (2021)
Edoardo Errichiello, Guido Zagnoli-Vieira, Romana Rizzi, Livia Garavelli, Keith W Caldecott, Orsetta Zuffardi
Characterization of a novel loss-of-function variant in TDP2 in two adult patients with spinocerebellar ataxia autosomal recessive 23 (SCAR23). Journal of human genetics 65 (12) (2020)
Hana Hanzlikova, Evgeniia A Prokhorova, Katerina Krejcikova, Zuzana Cihlarova, Ilona Kalasova, Jan Kubovciak, Jana Sachova, Richard Hailstone, Jan Brazina, Shereen Ghosh, Sebahattin Cirak, Joseph G Gleeson, Ivan Ahel, Keith W Caldecott
Pathogenic ARH3 mutations result in ADP-ribose chromatin scars during DNA strand break repair. Nature communications 11 (1) (2020)
Areej Mahjoub, Zuzana Cihlarova, Martine Tétreault, Lauren MacNeil, Neal Sondheimer, Keith W Caldecott, Hana Hanzlikova, Grace Yoon, null null
Homozygous pathogenic variant in BRAT1 associated with nonprogressive cerebellar ataxia. Neurology. Genetics 5 (5) (2019)
Emilia Komulainen, Lewis Pennicott, Darren Le Grand, Keith W Caldecott
Deazaflavin Inhibitors of TDP2 with Cellular Activity Can Affect Etoposide Influx and/or Efflux. ACS chemical biology 14 (6) (2019)
Maria Isabel Martinez-Macias, Duncan Aq Moore, Ryan L Green, Fernando Gomez-Herreros, Marcel Naumann, Andreas Hermann, Philip Van Damme, Majid Hafezparast, Keith W Caldecott
FUS (fused in sarcoma) is a component of the cellular response to topoisomerase I-induced DNA breakage and transcriptional stress. Life science alliance 2 (2) (2019)