Raj Chari

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 40

Top Topics

Transcription Factor

Dna Damage Response

Top Venues

Nature communications

The EMBO journal

Nature genetics

Science (New York, N.Y.)

This page only lists publications with an associated author ORCID identifier.

Publications

Liping Yang, Timothy P Sheets, Yang Feng, Guojun Yu, Pradip Bajgain, Kuo-Sheng Hsu, Daeho So, Steven Seaman, Jae-Won Lee, Ling Lin, Christine N Evans, Mary R Guest, Raj Chari, Brad St Croix
Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform. Science advances 10 (7) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew Am Todd, Vishal N Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. The EMBO journal 43 (11) (2024)
Supuni Thalalla Gamage, Roxane Khoogar, Shereen Howpay Manage, McKenna C Crawford, Joe Georgeson, Bogdan V Polevoda, Chelsea Sanders, Kendall A Lee, Kellie D Nance, Vinithra Iyer, Anatoly Kustanovich, Minervo Perez, Chu T Thu, Sam R Nance, Ruhul Amin, Christine N Miller, Ronald J Holewinski, Thomas Meyer, Vishal N Koparde, Acong Yang, Parthav Jailwala, Joe Truong Nguyen, Thorkell Andressen, Kent W Hunter, Shuo Gu, Beverly A Mock, Elijah F Edmondson, Simone Difilippantonio, Raj Chari, Schraga Schwartz, Mitchell R O'Connell, Colin Chih-Chien Wu, Jordan L Meier
Transfer RNA acetylation regulates in vivo mammalian stress signaling. bioRxiv : the preprint server for biology (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Supuni Thalalla Gamage, Roxane Khoogar, Shereen Howpay Manage, McKenna C Crawford, Joe Georgeson, Bogdan V Polevoda, Chelsea Sanders, Kendall A Lee, Kellie D Nance, Vinithra Iyer, Anatoly Kustanovich, Minervo Perez, Chu T Thu, Sam R Nance, Ruhul Amin, Christine N Miller, Ronald J Holewinski, Thomas Meyer, Vishal N Koparde, Acong Yang, Parthav Jailwala, Joe Truong Nguyen, Thorkell Andressen, Kent W Hunter, Shuo Gu, Beverly A Mock, Elijah F Edmondson, Simone Difilippantonio, Raj Chari, Schraga Schwartz, Mitchell R O'Connell, Colin Chih-Chien Wu, Jordan L Meier
Transfer RNA acetylation regulates in vivo mammalian stress signaling. bioRxiv : the preprint server for biology (2024)
Liping Yang, Timothy P Sheets, Yang Feng, Guojun Yu, Pradip Bajgain, Kuo-Sheng Hsu, Daeho So, Steven Seaman, Jae-Won Lee, Ling Lin, Christine N Evans, Mary R Guest, Raj Chari, Brad St Croix
Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform. Science advances 10 (7) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew Am Todd, Vishal N Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. The EMBO journal 43 (11) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Raphael S Pavani, Veenu Tripathi, Kyle B Vrtis, Dali Zong, Raj Chari, Elsa Callen, Ajith V Pankajam, Gang Zhen, Gabriel E Matos-Rodrigues, Jiajie Yang, Shuheng Wu, Giordano Reginato, Wei Wu, Peter Cejka, Johannes C Walter, Andrè Nussenzweig
Structure and repair of replication-coupled DNA breaks. Science (New York, N.Y.) (2024)
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew Am Todd, Vishal N Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. The EMBO journal 43 (11) (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew Am Todd, Vishal N Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. The EMBO journal (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew Am Todd, Vishal N Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. The EMBO journal 43 (11) (2024)
Xiuxiu Lu, Monika Chandravanshi, Venkata R Sabbasani, Snehal Gaikwad, V Keith Hughitt, Nana Gyabaah-Kessie, Bradley T Scroggins, Sudipto Das, Wazo Myint, Michelle E Clapp, Charles D Schwieters, Marzena A Dyba, Derek L Bolhuis, Janusz W Koscielniak, Thorkell Andresson, Michael J Emanuele, Nicholas G Brown, Hiroshi Matsuo, Raj Chari, Deborah E Citrin, Beverly A Mock, Rolf E Swenson, Kylie J Walters
A structure-based designed small molecule depletes hRpn13 Pru and a select group of KEN box proteins. Nature communications 15 (1) (2024)
Liping Yang, Timothy P Sheets, Yang Feng, Guojun Yu, Pradip Bajgain, Kuo-Sheng Hsu, Daeho So, Steven Seaman, Jae-Won Lee, Ling Lin, Christine N Evans, Mary R Guest, Raj Chari, Brad St Croix
Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform. Science advances 10 (7) (2024)
Raphael S Pavani, Veenu Tripathi, Kyle B Vrtis, Dali Zong, Raj Chari, Elsa Callen, Ajith V Pankajam, Gang Zhen, Gabriel E Matos-Rodrigues, Jiajie Yang, Shuheng Wu, Giordano Reginato, Wei Wu, Peter Cejka, Johannes C Walter, Andrè Nussenzweig
Structure and repair of replication-coupled DNA breaks. Science (New York, N.Y.) 385 (6710) (2024)
Liping Yang, Timothy P Sheets, Yang Feng, Guojun Yu, Pradip Bajgain, Kuo-Sheng Hsu, Daeho So, Steven Seaman, Jae-Won Lee, Ling Lin, Christine N Evans, Mary R Guest, Raj Chari, Brad St Croix
Uncovering receptor-ligand interactions using a high-avidity CRISPR activation screening platform. Science advances 10 (7) (2024)
Raphael S Pavani, Veenu Tripathi, Kyle B Vrtis, Dali Zong, Raj Chari, Elsa Callen, Ajith V Pankajam, Gang Zhen, Gabriel E Matos-Rodrigues, Jiajie Yang, Shuheng Wu, Giordano Reginato, Wei Wu, Peter Cejka, Johannes C Walter, Andrè Nussenzweig
Structure and repair of replication-coupled DNA breaks. Science (New York, N.Y.) (2024)
Vinutha Balachandra, Roshan L Shrestha, Colin M Hammond, Shinjen Lin, Ivo A Hendriks, Subhash Chandra Sethi, Lu Chen, Samantha Sevilla, Natasha J Caplen, Raj Chari, Tatiana S Karpova, Katherine McKinnon, Matthew Am Todd, Vishal N Koparde, Ken Chih-Chien Cheng, Michael L Nielsen, Anja Groth, Munira A Basrai
DNAJC9 prevents CENP-A mislocalization and chromosomal instability by maintaining the fidelity of histone supply chains. The EMBO journal (2024)
Yong Yean Kim, Berkley E Gryder, Ranuka Sinniah, Megan L Peach, Jack F Shern, Abdalla Abdelmaksoud, Silvia Pomella, Girma M Woldemichael, Benjamin Z Stanton, David Milewski, Joseph J Barchi, John S Schneekloth, Raj Chari, Joshua T Kowalczyk, Shilpa R Shenoy, Jason R Evans, Young K Song, Chaoyu Wang, Xinyu Wen, Hsien-Chao Chou, Vineela Gangalapudi, Dominic Esposito, Jane Jones, Lauren Procter, Maura O'Neill, Lisa M Miller Jenkins, Nadya I Tarasova, Jun S Wei, James B McMahon, Barry R Oâ Keefe, Robert G Hawley, Javed Khan
KDM3B inhibitors disrupt the oncogenic activity of PAX3-FOXO1 in fusion-positive rhabdomyosarcoma. Nature communications 15 (1) (2024)
Joseph K McKenna, Yalan Wu, Praveen Sonkusre, Raj Chari, Andres M Lebensohn
The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability. bioRxiv : the preprint server for biology (2024)
Raphael S Pavani, Veenu Tripathi, Kyle B Vrtis, Dali Zong, Raj Chari, Elsa Callen, Ajith V Pankajam, Gang Zhen, Gabriel E Matos-Rodrigues, Jiajie Yang, Shuheng Wu, Giordano Reginato, Wei Wu, Peter Cejka, Johannes C Walter, Andrè Nussenzweig
Structure and repair of replication-coupled DNA breaks. Science (New York, N.Y.) 385 (6710) (2024)
Joseph K McKenna, Yalan Wu, Praveen Sonkusre, Raj Chari, Andres M Lebensohn
The ubiquitin ligase HUWE1 enhances WNT signaling by antagonizing destruction complex-mediated β-catenin degradation and through a mechanism independent of β-catenin stability. bioRxiv : the preprint server for biology (2024)
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C Tobias, Sakthi D Moorthy, Ryan K Dale, Jennifer A Mitchell, Timothy J Petros, Pedro P Rocha
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nature genetics 55 (2) (2023)
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C Tobias, Sakthi D Moorthy, Ryan K Dale, Jennifer A Mitchell, Timothy J Petros, Pedro P Rocha
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nature genetics (2023)
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C Tobias, Sakthi D Moorthy, Ryan K Dale, Jennifer A Mitchell, Timothy J Petros, Pedro P Rocha
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nature genetics 55 (2) (2023)
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C Tobias, Sakthi D Moorthy, Ryan K Dale, Jennifer A Mitchell, Timothy J Petros, Pedro P Rocha
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nature genetics (2023)
Olga Kim, Madison Butler, Zach Sergi, Robert W Robey, Meili Zhang, Raj Chari, Ying Pang, Guangyang Yu, Wei Zhang, Hua Song, Dionne Davis, Robert G Hawley, Xinyu Wen, Herui Wang, Martha Quezado, Bao Tran, Mythili Merchant, Alice Ranjan, Frank B Furnari, Javed Khan, Mark R Gilbert, Christopher Ryan Miller, Michael M Gottesman, Yves Pommier, Jing Wu
Combined inhibition of topoisomerase I and poly(ADP-ribose) polymerase: A synergistic therapeutic strategy for glioblastoma with phosphatase and tensin homolog deficiency. Neuro-oncology advances 5 (1) (2023)
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C Tobias, Sakthi D Moorthy, Ryan K Dale, Jennifer A Mitchell, Timothy J Petros, Pedro P Rocha
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nature genetics 55 (2) (2023)
Laura Sala, Manish Kumar, Mahendra Prajapat, Srividya Chandrasekhar, Rachel L Cosby, Gaspare La Rocca, Todd S Macfarlan, Parirokh Awasthi, Raj Chari, Michael Kruhlak, Joana A Vidigal
AGO2 silences mobile transposons in the nucleus of quiescent cells. Nature structural & molecular biology (2023)
Shreeta Chakraborty, Nina Kopitchinski, Zhenyu Zuo, Ariel Eraso, Parirokh Awasthi, Raj Chari, Apratim Mitra, Ian C Tobias, Sakthi D Moorthy, Ryan K Dale, Jennifer A Mitchell, Timothy J Petros, Pedro P Rocha
Enhancer-promoter interactions can bypass CTCF-mediated boundaries and contribute to phenotypic robustness. Nature genetics (2023)
Dongpeng Wang, Wei Wu, Elsa Callen, Raphael S Pavani, Nicholas Zolnerowich, Srikanth Kodali, Dali Zong, Nancy Wong, Santiago Noriega, William J Nathan, Gabriel E Matos-Rodrigues, Raj Chari, Michael J Kruhlak, Ferenc Livak, Michael Emmerson Ward, Keith W Caldecott, Bruno Di Stefano, Andrè Nussenzweig
Active DNA demethylation promotes cell fate specification and the DNA damage response. Science (New York, N.Y.) 378 (6623) (2022)
Poonam Tewary, Alan D Brooks, Ya-Ming Xu, E M Kithsiri Wijeratne, Ashley L Babyak, Timothy C Back, Raj Chari, Christine N Evans, Curtis J Henrich, Thomas J Meyer, Elijah F Edmondson, Maria T Prudente de Aquino, Thanigaivelan Kanagasabai, Anil Shanker, A A Leslie Gunatilaka, Thomas J Sayers
Small-Molecule Natural Product Physachenolide C Potentiates Immunotherapy Efficacy by Targeting BET Proteins. Cancer research 81 (12) (2021)
Benjamin Ruf, Vanessa V Catania, Simon Wabitsch, Chi Ma, Laurence P Diggs, Qianfei Zhang, Bernd Heinrich, Varun Subramanyam, Linda L Cui, Marie Pouzolles, Christine N Evans, Raj Chari, Shunsuke Sakai, Sangmi Oh, Clifton Earl Barry, Daniel L Barber, Tim F Greten
Activating Mucosal-Associated Invariant T Cells Induces a Broad Antitumor Response. Cancer immunology research 9 (9) (2021)
Raj Chari, Nan Cher Yeo, Alejandro Chavez, George M Church
sgRNA Scorer 2.0: A Species-Independent Model To Predict CRISPR/Cas9 Activity. ACS synthetic biology 6 (5) (2017)