Kenneth M Murphy

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 29

Top Topics

Peripheral Blood

Dendritic Cells

Top Venues

The Journal of experimental medicine

Journal of immunology (Baltimore, Md. : 1950)

Nature immunology

This page only lists publications with an associated author ORCID identifier.

Publications

Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature 632 (8023) (2024)
Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature 632 (8023) (2024)
Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature 632 (8023) (2024)
Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature 632 (8023) (2024)
Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature (2024)
Hussein Sultan, Yoshiko Takeuchi, Jeffrey P Ward, Naveen Sharma, Tian-Tian Liu, Vladimir Sukhov, Maria Firulyova, Yuang Song, Samuel Ameh, Simone Brioschi, Darya Khantakova, Cora D Arthur, J Michael White, Heather Kohlmiller, Andres M Salazar, Robert Burns, Helio A Costa, Kelly D Moynihan, Yik Andy Yeung, Ivana Djuretic, Ton N Schumacher, Kathleen C F Sheehan, Marco Colonna, James P Allison, Kenneth M Murphy, Maxim N Artyomov, Robert D Schreiber
Neoantigen-specific cytotoxic Tr1 CD4 T cells suppress cancer immunotherapy. Nature 632 (8023) (2024)
Kenneth M Murphy
"Doubt No More": Two Sizes Fit All. Journal of immunology (Baltimore, Md. : 1950) 211 (1) (2023)
Tian-Tian Liu, Feiya Ou, Julia A Belk, Prachi Bagadia, David A Anderson, Vivek Durai, Winnie Yao, Ansuman T Satpathy, Theresa L Murphy, Kenneth M Murphy
Cis interactions in the Irf8 locus regulate stage-dependent enhancer activation. Genes & development (2023)
Feiya Ou, Stephen T Ferris, Sunkyung Kim, Renee Wu, David A Anderson, Tian-Tian Liu, Suin Jo, Michael Y Chen, William E Gillanders, Theresa L Murphy, Kenneth M Murphy
Enhanced in vitro type 1 conventional dendritic cell generation via the recruitment of hematopoietic stem cells and early progenitors by Kit ligand. European journal of immunology (2023)
Sunkyung Kim, Jing Chen, Suin Jo, Feiya Ou, Stephen T Ferris, Tian-Tian Liu, Ray A Ohara, David A Anderson, Renee Wu, Michael Y Chen, William E Gillanders, William E Gillanders, Theresa L Murphy, Kenneth M Murphy
IL-6 selectively suppresses cDC1 specification via C/EBPβ. The Journal of experimental medicine 220 (10) (2023)
Renee Wu, Kenneth M Murphy
DCs at the center of help: Origins and evolution of the three-cell-type hypothesis. The Journal of experimental medicine 219 (7) (2022)
Renee Wu, Ray A Ohara, Suin Jo, Tian-Tian Liu, Stephen T Ferris, Feiya Ou, Sunkyung Kim, Derek J Theisen, David A Anderson, Brian W Wong, Timothy Gershon, Robert D Schreiber, Theresa L Murphy, Kenneth M Murphy
Mechanisms of CD40-dependent cDC1 licensing beyond costimulation. Nature immunology 23 (11) (2022)
Chin-Wen Lai, Prachi Bagadia, Derek A G Barisas, Nicholas N Jarjour, Rachel Wong, Takahiro Ohara, Brian D Muegge, Qiuhe Lu, Shanshan Xiong, Brian T Edelson, Kenneth M Murphy, Thaddeus S Stappenbeck
Mesothelium-Derived Factors Shape GATA6-Positive Large Cavity Macrophages. Journal of immunology (Baltimore, Md. : 1950) 209 (4) (2022)
Tian-Tian Liu, Sunkyung Kim, Pritesh Desai, Do-Hyun Kim, Xiao Huang, Stephen T Ferris, Renee Wu, Feiya Ou, Takeshi Egawa, Steven J Van Dyken, Michael S. Diamond, Peter F Johnson, Masato Kubo, Theresa L Murphy, Kenneth M Murphy
Ablation of cDC2 development by triple mutations within the Zeb2 enhancer. Nature 607 (7917) (2022)
Stephen T Ferris, Ray A Ohara, Feiya Ou, Renee Wu, Xiao Huang, Sunkyung Kim, Jing Chen, Tian-Tian Liu, Robert D Schreiber, Theresa L Murphy, Kenneth M Murphy
cDC1 Vaccines Drive Tumor Rejection by Direct Presentation Independently of Host cDC1. Cancer immunology research 10 (8) (2022)
Jay A Bowman-Kirigin, Rupen Desai, Brian T Saunders, Anthony Z Wang, Maximilian O Schaettler, Connor J Liu, Alexandra J Livingstone, Dale K Kobayashi, Vivek Durai, Nicole M Kretzer, Gregory J Zipfel, Eric C Leuthardt, Joshua W Osbun, Michael R Chicoine, Albert H Kim, Kenneth M Murphy, Tanner M Johanns, Bernd H Zinselmeyer, Gavin P Dunn
The conventional dendritic cell 1 subset primes CD8+ T cells and traffics tumor antigen to drive anti-tumor immunity in the brain. Cancer immunology research (2022)
Prachi Bagadia, Kevin W O'Connor, Renee Wu, Stephen T Ferris, Jeffrey P Ward, Robert D Schreiber, Theresa L Murphy, Kenneth M Murphy
Bcl6-Independent In Vivo Development of Functional Type 1 Classical Dendritic Cells Supporting Tumor Rejection. Journal of immunology (Baltimore, Md. : 1950) (2021)
David A Anderson, Feiya Ou, Sunkyung Kim, Theresa L Murphy, Kenneth M Murphy
Transition from cMyc to L-Myc during dendritic cell development coordinated by rising levels of IRF8. The Journal of experimental medicine 219 (2) (2021)
Theresa L Murphy, Kenneth M Murphy
Dendritic cells in cancer immunology. Cellular & molecular immunology (2021)
Stephen T Ferris, Vivek Durai, Renee Wu, Derek J Theisen, Jeffrey P Ward, Michael D Bern, Jesse T Davidson, Prachi Bagadia, Tiantian Liu, Carlos G Briseño, Lijin Li, William E Gillanders, Gregory F Wu, Wayne M Yokoyama, Theresa L Murphy, Robert D Schreiber, Kenneth M Murphy
cDC1 prime and are licensed by CD4+ T cells to induce anti-tumour immunity. Nature 584 (7822) (2020)
Mushtaq Ahmed, Shyamala Thirunavukkarasu, Bruce A Rosa, Kimberly A Thomas, Shibali Das, Javier Rangel-Moreno, Lan Lu, Smriti Mehra, Stanley Kimbung Mbandi, Larissa B Thackray, Michael S Diamond, Kenneth M Murphy, Terry K Means, John Martin, Deepak Kaushal, Thomas Jens Scriba, Makedonka Mitreva, Shabaana Abdul Khader
Immune correlates of tuberculosis disease and risk translate across species. Science translational medicine 12 (528) (2020)
Vivek Durai, Prachi Bagadia, Jeffrey M Granja, Ansuman T Satpathy, Devesha H Kulkarni, Jesse T Davidson, Renee Wu, Swapneel J Patel, Arifumi Iwata, Tian-Tian Liu, Xiao Huang, Carlos G Briseño, Gary E Grajales-Reyes, Miriam Wöhner, Hiromi Tagoh, Barbara L Kee, Rodney D Newberry, Meinrad Busslinger, Howard Y Chang, Theresa L Murphy, Kenneth M Murphy
Cryptic activation of an Irf8 enhancer governs cDC1 fate specification. Nature immunology 20 (9) (2019)
Prachi Bagadia, Xiao Huang, Tian-Tian Liu, Vivek Durai, Gary E Grajales-Reyes, Maximilian Nitschké, Zora Modrusan, Jeffrey M Granja, Ansuman T Satpathy, Carlos G Briseño, Marco Gargaro, Arifumi Iwata, Sunkyung Kim, Howard Y Chang, Andrey S Shaw, Theresa L Murphy, Kenneth M Murphy
An Nfil3-Zeb2-Id2 pathway imposes Irf8 enhancer switching during cDC1 development. Nature immunology 20 (9) (2019)
Derek J Theisen, Jesse T Davidson, Carlos G Briseño, Marco Gargaro, Elvin J Lauron, Qiuling Wang, Pritesh Desai, Vivek Durai, Prachi Bagadia, Joshua R Brickner, Wandy L Beatty, Herbert W Virgin, William E Gillanders, Nima Mosammaparast, Michael S. Diamond, L David Sibley, Wayne M Yokoyama, Robert D Schreiber, Theresa L Murphy, Kenneth M Murphy
WDFY4 is required for cross-presentation in response to viral and tumor antigens. Science (New York, N.Y.) 362 (6415) (2019)
Ashley A Viehmann Milam, Juliet M Bartleson, David L Donermeyer, Stephen C Horvath, Vivek Durai, Saravanan Raju, Haiyang Yu, Veronika Redmann, Bernd Zinselmeyer, J Michael White, Kenneth M Murphy, Paul M Allen
Tuning T Cell Signaling Sensitivity Alters the Behavior of CD4+ T Cells during an Immune Response. Journal of immunology (Baltimore, Md. : 1950) 200 (10) (2018)
Derek J Theisen, Stephen T Ferris, Carlos G Briseño, Nicole Kretzer, Arifumi Iwata, Kenneth M Murphy
Batf3-Dependent Genes Control Tumor Rejection Induced by Dendritic Cells Independently of Cross-Presentation. Cancer immunology research 7 (1) (2018)
Vivek Durai, Prachi Bagadia, Carlos G Briseño, Derek J Theisen, Arifumi Iwata, Jesse T Davidson, Marco Gargaro, Daved H Fremont, Theresa L Murphy, Kenneth M Murphy
Altered compensatory cytokine signaling underlies the discrepancy between Flt3-/- and Flt3l-/- mice. The Journal of experimental medicine 215 (5) (2018)
Joanna E Klementowicz, Ashley E Mahne, Allyson Spence, Vinh Nguyen, Ansuman T Satpathy, Kenneth M Murphy, Qizhi Tang
Cutting Edge: Origins, Recruitment, and Regulation of CD11c+ Cells in Inflamed Islets of Autoimmune Diabetes Mice. Journal of immunology (Baltimore, Md. : 1950) 199 (1) (2017)
Xiaodi Wu, Carlos G Briseño, Vivek Durai, Jörn C Albring, Malay Haldar, Prachi Bagadia, Ki-Wook Kim, Gwendalyn J Randolph, Theresa L Murphy, Kenneth M Murphy
Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells. The Journal of experimental medicine 213 (12) (2016)