Kevin William Plaxco (Kyle L Ploense, Kevin W Plaxco)

ResearcherID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 62

Top Venues

ACS sensors

Angewandte Chemie (International ed. in English)

Journal of the American Chemical Society

Lab on a chip

Oxford University

California Institute of Technology (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Oxford University

United Kingdom

Postdoc

Education History

California Institute of Technology

United States

PHD :: Biology division

Publications

Elsi Mynttinen, Julian Gerson, Kaylyn Leung, Tod E Kippin, Kevin William Plaxco
Dual-Frequency, Ratiometric Approaches to EAB Sensor Interrogation Support the Calibration-Free Measurement of Specific Molecules In Vivo. ACS sensors (2024)
Yiling Yang, Xumei Gao, Bryce Widdicombe, Xiaodan Zhang, Jana Lorraine Zielinski, Tianhong Cheng, Avanka Gunatilaka, Kaylyn K Leung, Kevin William Plaxco, Ranjith Rajasekharan Unnithan, Alastair G Stewart
Dual-Purpose Aptamer-Based Sensors for Real-Time, Multiplexable Monitoring of Metabolites in Cell Culture Media. ACS nano (2024)
Yuyang Wu, Jinyuan Shi, Tod E Kippin, Kevin William Plaxco
Codeposition Enhances the Performance of Electrochemical Aptamer-Based Sensors. Langmuir : the ACS journal of surfaces and colloids (2024)
Yuyang Wu, Jinyuan Shi, Tod E Kippin, Kevin William Plaxco
Codeposition Enhances the Performance of Electrochemical Aptamer-Based Sensors. Langmuir : the ACS journal of surfaces and colloids 40 (16) (2024)
Elsi Mynttinen, Julian Gerson, Kaylyn Leung, Tod E Kippin, Kevin William Plaxco
Dual-Frequency, Ratiometric Approaches to EAB Sensor Interrogation Support the Calibration-Free Measurement of Specific Molecules In Vivo. ACS sensors 9 (6) (2024)
Julia Chung, Adriana Billante, Charlotte Flatebo, Kaylyn K Leung, Julian Gerson, Nicole Emmons, Tod E Kippin, Lior Sepunaru, Kevin William Plaxco
Effects of storage conditions on the performance of an electrochemical aptamer-based sensor. Sensors & diagnostics 3 (6) (2024)
Julia Chung, Adriana Billante, Charlotte Flatebo, Kaylyn K Leung, Julian Gerson, Nicole Emmons, Tod E Kippin, Lior Sepunaru, Kevin William Plaxco
Effects of storage conditions on the performance of an electrochemical aptamer-based sensor. Sensors & diagnostics 3 (6) (2024)
Kaylyn K Leung, Julian Gerson, Nicole Emmons, Jennifer M Heemstra, Tod E Kippin, Kevin William Plaxco
The Use of Xenonucleic Acids Significantly Reduces theIn Vivo Drift of Electrochemical Aptamer-Based Sensors. Angewandte Chemie (International ed. in English) (2024)
Julia Chung, Adriana Billante, Charlotte Flatebo, Kaylyn K Leung, Julian Gerson, Nicole Emmons, Tod E Kippin, Lior Sepunaru, Kevin William Plaxco
Effects of storage conditions on the performance of an electrochemical aptamer-based sensor. Sensors & diagnostics 3 (6) (2024)
Kaylyn K Leung, Julian Gerson, Nicole Emmons, Jennifer M Heemstra, Tod E Kippin, Kevin William Plaxco
The Use of Xenonucleic Acids Significantly Reduces the In Vivo Drift of Electrochemical Aptamer-Based Sensors. Angewandte Chemie (International ed. in English) 63 (21) (2024)
Kaylyn K Leung, Julian Gerson, Nicole Emmons, Jennifer M Heemstra, Tod E Kippin, Kevin William Plaxco
The Use of Xenonucleic Acids Significantly Reduces the In Vivo Drift of Electrochemical Aptamer-Based Sensors. Angewandte Chemie (International ed. in English) 63 (21) (2024)
Mark Friedel, Benjamin Werbovetz, Amy Drexelius, Zach Watkins, Ahilya Bali, Kevin William Plaxco, Jason Heikenfeld
Continuous molecular monitoring of human dermal interstitial fluid with microneedle-enabled electrochemical aptamer sensors. Lab on a chip (2023)
Claudio Parolo, Andrea Idili, Jason Heikenfeld, Kevin William Plaxco
Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices. Lab on a chip (2023)
Claudio Parolo, Andrea Idili, Jason Heikenfeld, Kevin William Plaxco
Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices. Lab on a chip 23 (5) (2023)
Claudio Parolo, Andrea Idili, Jason Heikenfeld, Kevin William Plaxco
Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices. Lab on a chip 23 (5) (2023)
Shaoguang Li, Jun Dai, Man Zhu, Netzahualcóyotl Arroyo-Currás, Hongxing Li, Yuanyuan Wang, Quan Wang, Xiaoding Lou, Tod E Kippin, Shixuan Wang, Kevin William Plaxco, Hui Li, Fan Xia
Implantable Hydrogel-Protective DNA Aptamer-Based Sensor Supports Accurate, Continuous Electrochemical Analysis of Drugs at Multiple Sites in Living Rats. ACS nano (2023)
Kaylyn K Leung, Julian Gerson, Nicole A Emmons, Brian Roehrich, Elsi Mynttinen, Lisa C Fetter, Tod E Kippin, Kevin William Plaxco
A tight squeeze: geometric effects on the performance of three-electrode electrochemical-aptamer based sensors in constrained, in vivo placements. The Analyst (2023)
Ruvimbo Dephine Mishi, Michael Andrew Stokes, Craig Anthony Campbell, Kevin William Plaxco, Sophie Lena Stocker
Real-Time Monitoring of Antibiotics in the Critically Ill Using Biosensors. Antibiotics (Basel, Switzerland) 12 (10) (2023)
Claudio Parolo, Andrea Idili, Jason Heikenfeld, Kevin William Plaxco
Conformational-switch biosensors as novel tools to support continuous, real-time molecular monitoring in lab-on-a-chip devices. Lab on a chip 23 (5) (2023)
Alex M Downs, Kevin William Plaxco
Real-Time, In Vivo Molecular Monitoring Using Electrochemical Aptamer Based Sensors: Opportunities and Challenges. ACS sensors 7 (10) (2022)
Yuyang Wu, Simona Ranallo, Erica Del Grosso, Alejandro Chamoro-Garcia, Herbert L Ennis, Nenad Milosavić, Kyung-Ae Yang, Tod Kippin, Francesco Ricci, Milan Stojanovic, Kevin William Plaxco
Using Spectroscopy to Guide the Adaptation of Aptamers into Electrochemical Aptamer-Based Sensors. Bioconjugate chemistry (2022)
Alejandro Chamoro-Garcia, Julian Gerson, Charlotte Flatebo, Lisa Fetter, Alex M Downs, Nicole Emmons, Herbert L Ennis, Nenad Milosavić, Kyung-Ae Yang, Milan Stojanovic, Francesco Ricci, Tod E Kippin, Kevin William Plaxco
Real-Time, Seconds-Resolved Measurements of Plasma Methotrexate In Situ in the Living Body. ACS sensors 8 (1) (2022)
Alejandro Chamoro-Garcia, Julian Gerson, Charlotte Flatebo, Lisa Fetter, Alex M Downs, Nicole Emmons, Herbert L Ennis, Nenad Milosavić, Kyung-Ae Yang, Milan Stojanovic, Francesco Ricci, Tod E Kippin, Kevin William Plaxco
Real-Time, Seconds-Resolved Measurements of Plasma Methotrexate In Situ in the Living Body. ACS sensors (2022)
Alejandro Chamoro-Garcia, Julian Gerson, Charlotte Flatebo, Lisa Fetter, Alex M Downs, Nicole Emmons, Herbert L Ennis, Nenad Milosavić, Kyung-Ae Yang, Milan Stojanovic, Francesco Ricci, Tod E Kippin, Kevin William Plaxco
Real-Time, Seconds-Resolved Measurements of Plasma Methotrexate In Situ in the Living Body. ACS sensors 8 (1) (2022)
Alejandro Chamoro-Garcia, Claudio Parolo, Gabriel Ortega, Andrea Idili, Joshua Green, Francesco Ricci, Kevin William Plaxco
The sequestration mechanism as a generalizable approach to improve the sensitivity of biosensors and bioassays. Chemical science 13 (41) (2022)
Alejandro Chamoro-Garcia, Julian Gerson, Charlotte Flatebo, Lisa Fetter, Alex M Downs, Nicole Emmons, Herbert L Ennis, Nenad Milosavić, Kyung-Ae Yang, Milan Stojanovic, Francesco Ricci, Tod E Kippin, Kevin William Plaxco
Real-Time, Seconds-Resolved Measurements of Plasma Methotrexate In Situ in the Living Body. ACS sensors 8 (1) (2022)
Andrea Idili, Julian Gerson, Tod Kippin, Kevin William Plaxco
Seconds-Resolved, In Situ Measurements of Plasma Phenylalanine Disposition Kinetics in Living Rats. Analytical chemistry 93 (8) (2021)
Kaylyn K Leung, Alex M Downs, Gabriel Ortega, Martin Kurnik, Kevin William Plaxco
Elucidating the Mechanisms Underlying the Signal Drift of Electrochemical Aptamer-Based Sensors in Whole Blood. ACS sensors 6 (9) (2021)
Di Kang, Jing Yu, Fan Xia, Jun Huang, Hongbo Zeng, Matthew V Tirrell, Jacob N Israelachvili, Kevin William Plaxco
Nanometer-Scale Force Profiles of Short Single- and Double-Stranded DNA Molecules on a Gold Surface Measured Using a Surface Forces Apparatus. Langmuir : the ACS journal of surfaces and colloids 37 (45) (2021)
Shaoguang Li, Lancy Lin, Xueman Chang, Zhixiao Si, Kevin William Plaxco, Michelle Khine, Hui Li, Fan Xia
A wrinkled structure of gold film greatly improves the signaling of electrochemical aptamer-based biosensors. RSC advances 11 (2) (2021)
Alejandro Chamoro-Garcia, Gabriel Ortega, Davide Mariottini, Joshua Green, Francesco Ricci, Kevin William Plaxco
Switching the aptamer attachment geometry can dramatically alter the signalling and performance of electrochemical aptamer-based sensors. Chemical communications (Cambridge, England) 57 (88) (2021)
Julia Chung, Phoebe Hertler, Kevin William Plaxco, Lior Sepunaru
Catalytic Interruption Mitigates Edge Effects in the Characterization of Heterogeneous, Insulating Nanoparticles. Journal of the American Chemical Society 143 (45) (2021)
Gabriel Ortega, Miguel A Aguilar, Bishal K Gautam, Kevin William Plaxco
The effect of charged residue substitutions on the thermodynamics of protein-surface interactions. Protein science : a publication of the Protein Society 30 (12) (2021)
Sara Bracaglia, Simona Ranallo, Kevin William Plaxco, Francesco Ricci
Programmable, Multiplexed DNA Circuits Supporting Clinically Relevant, Electrochemical Antibody Detection. ACS sensors 6 (6) (2021)
Kevin J Cash, Kevin William Plaxco
Signal transduction with a swing. Nature chemistry 13 (5) (2021)
Alex M Downs, Julian Gerson, M Nur Hossain, Kyle Ploense, Michael Pham, Heinz-Bernhard Kraatz, Tod Kippin, Kevin William Plaxco
Nanoporous Gold for the Miniaturization of In Vivo Electrochemical Aptamer-Based Sensors. ACS sensors 6 (6) (2021)
Claudio Parolo, Andrea Idili, Gabriel Ortega, Andrew Csordas, Alex Hsu, Netzahualcóyotl Arroyo-Currás, Qin Yang, Brian Scott Ferguson, Jinpeng Wang, Kevin William Plaxco
Real-Time Monitoring of a Protein Biomarker. ACS sensors 5 (7) (2020)
Alex M Downs, Julian Gerson, Kyle L Ploense, Kevin William Plaxco, Philippe Dauphin-Ducharme
Subsecond-Resolved Molecular Measurements Using Electrochemical Phase Interrogation of Aptamer-Based Sensors. Analytical chemistry 92 (20) (2020)
Gabriel Ortega, Davide Mariottini, Alessandra Troina, Frederick W Dahlquist, Francesco Ricci, Kevin William Plaxco
Rational design to control the trade-off between receptor affinity and cooperativity. Proceedings of the National Academy of Sciences of the United States of America 117 (32) (2020)
Gabriel Ortega, Martin Kurnik, Bishal K Gautam, Kevin William Plaxco
Attachment of Proteins to a Hydroxyl-Terminated Surface Eliminates the Stabilizing Effects of Polyols. Journal of the American Chemical Society 142 (36) (2020)
Stéphanie Bissonnette, Erica Del Grosso, Anna J Simon, Kevin William Plaxco, Francesco Ricci, Alexis Vallée-Bélisle
Optimizing the Specificity Window of Biomolecular Receptors Using Structure-Switching and Allostery. ACS sensors 5 (7) (2020)
Martin Kurnik, Eric Z Pang, Kevin William Plaxco
An Electrochemical Biosensor Architecture Based on Protein Folding Supports Direct Real-Time Measurements in Whole Blood. Angewandte Chemie (International ed. in English) 59 (42) (2020)
Samuel D Curtis, Kyle L Ploense, Martin Kurnik, Gabriel Ortega, Claudio Parolo, Tod E Kippin, Kevin William Plaxco, Netzahualcóyotl Arroyo-Currás
Open Source Software for the Real-Time Control, Processing, and Visualization of High-Volume Electrochemical Data. Analytical chemistry 91 (19) (2019)
Andrea Idili, Claudio Parolo, Gabriel Ortega, Kevin William Plaxco
Calibration-Free Measurement of Phenylalanine Levels in the Blood Using an Electrochemical Aptamer-Based Sensor Suitable for Point-of-Care Applications. ACS sensors 4 (12) (2019)
Joshua A Riback, Micayla A Bowman, Adam M Zmyslowski, Kevin William Plaxco, Patricia L Clark, Tobin R Sosnick
Commonly used FRET fluorophores promote collapse of an otherwise disordered protein. Proceedings of the National Academy of Sciences of the United States of America 116 (18) (2019)
Philippe Dauphin-Ducharme, Kyungae Yang, Netzahualcóyotl Arroyo-Currás, Kyle L Ploense, Yameng Zhang, Julian Gerson, Martin Kurnik, Tod E Kippin, Milan N Stojanovic, Kevin William Plaxco
Electrochemical Aptamer-Based Sensors for Improved Therapeutic Drug Monitoring and High-Precision, Feedback-Controlled Drug Delivery. ACS sensors 4 (10) (2019)
Gabriel Ortega, Martin Kurnik, Philippe Dauphin-Ducharme, Hui Li, Netzahualcóyotl Arroyo-Currás, Amanda Caceres, Kevin William Plaxco
Surface Attachment Enhances the Thermodynamic Stability of Protein L. Angewandte Chemie (International ed. in English) 58 (6) (2019)
Philippe Dauphin-Ducharme, Netzahualcóyotl Arroyo-Currás, Kevin William Plaxco
High-Precision Electrochemical Measurements of the Guanine-, Mismatch-, and Length-Dependence of Electron Transfer from Electrode-Bound DNA Are Consistent with a Contact-Mediated Mechanism. Journal of the American Chemical Society 141 (3) (2019)
Hui Li, Shaoguang Li, Jun Dai, Chengcheng Li, Man Zhu, Hongxing Li, Xiaoding Lou, Fan Xia, Kevin William Plaxco
High frequency, calibration-free molecular measurements in situ in the living body. Chemical science 10 (47) (2019)
Philippe Dauphin-Ducharme, Netzahualcóyotl Arroyo-Currás, Kevin William Plaxco
Correction to "High-Precision Electrochemical Measurements of the Guanine-, Mismatch-, and Length-Dependence of Electron Transfer from Electrode-Bound DNA Are Consistent with a Contact-Mediated Mechanism". Journal of the American Chemical Society 141 (19) (2019)
Andrea Idili, Netzahualcóyotl Arroyo-Currás, Kevin William Plaxco, Andrew T Csordas, Masayasu Kuwahara, Tod E Kippin, Kevin W Plaxco
Seconds-resolved pharmacokinetic measurements of the chemotherapeutic irinotecan in situ in the living body. Chemical science 10 (35) (2019)
Herschel M Watkins, Francesco Ricci, Kevin William Plaxco
Experimental Measurement of Surface Charge Effects on the Stability of a Surface-Bound Biopolymer. Langmuir : the ACS journal of surfaces and colloids 34 (49) (2018)
Di Kang, Claudio Parolo, Sheng Sun, Nathan E Ogden, Frederick W Dahlquist, Kevin William Plaxco
Expanding the Scope of Protein-Detecting Electrochemical DNA "Scaffold" Sensors. ACS sensors 3 (7) (2018)
Martin Kurnik, Gabriel Ortega, Philippe Dauphin-Ducharme, Hui Li, Amanda Caceres, Kevin William Plaxco
Quantitative measurements of protein-surface interaction thermodynamics. Proceedings of the National Academy of Sciences of the United States of America 115 (33) (2018)
Hui Li, Jacob Somerson, Fan Xia, Kevin William Plaxco
Electrochemical DNA-Based Sensors for Molecular Quality Control: Continuous, Real-Time Melamine Detection in Flowing Whole Milk. Analytical chemistry 90 (18) (2018)
Davide Mariottini, Andrea Idili, Alexis Vallée-Bélisle, Kevin William Plaxco, Francesco Ricci
A DNA Nanodevice That Loads and Releases a Cargo with Hemoglobin-Like Allosteric Control and Cooperativity. Nano letters 17 (5) (2017)
Hui Li, Philippe Dauphin-Ducharme, Gabriel Ortega, Kevin William Plaxco
Calibration-Free Electrochemical Biosensors Supporting Accurate Molecular Measurements Directly in Undiluted Whole Blood. Journal of the American Chemical Society 139 (32) (2017)
Di Kang, Sheng Sun, Martin Kurnik, Demosthenes Morales, Frederick W Dahlquist, Kevin William Plaxco
New Architecture for Reagentless, Protein-Based Electrochemical Biosensors. Journal of the American Chemical Society 139 (35) (2017)
Netzahualcóyotl Arroyo-Currás, Philippe Dauphin-Ducharme, Gabriel Ortega, Kyle L Ploense, Tod E Kippin, Kevin William Plaxco
Subsecond-Resolved Molecular Measurements in the Living Body Using Chronoamperometrically Interrogated Aptamer-Based Sensors. ACS sensors 3 (2) (2017)
Philippe Dauphin-Ducharme, Netzahualcóyotl Arroyo-Currás, Martin Kurnik, Gabriel Ortega, Hui Li, Kevin William Plaxco
Simulation-Based Approach to Determining Electron Transfer Rates Using Square-Wave Voltammetry. Langmuir : the ACS journal of surfaces and colloids 33 (18) (2017)
Hui Li, Philippe Dauphin-Ducharme, Netzahualcóyotl Arroyo-Currás, Claire H Tran, Philip A Vieira, Shaoguang Li, Christina Shin, Jacob Somerson, Tod E Kippin, Kevin William Plaxco
A Biomimetic Phosphatidylcholine-Terminated Monolayer Greatly Improves the In Vivo Performance of Electrochemical Aptamer-Based Sensors. Angewandte Chemie (International ed. in English) 56 (26) (2017)
Netzahualcóyotl Arroyo-Currás, Karen Scida, Kyle L Ploense, Tod E Kippin, Kevin William Plaxco
High Surface Area Electrodes Generated via Electrochemical Roughening Improve the Signaling of Electrochemical Aptamer-Based Biosensors. Analytical chemistry 89 (22) (2017)

Kevin William Plaxco.css-eqlu8i{font-size:small;padding-left:4px;} (Kyle L Ploense, Kevin W Plaxco)

Publication Activity (10 Years)

Top Topics

Top Venues

Kevin William Plaxco (Kyle L Ploense, Kevin W Plaxco)