Klemens Rottner

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 47

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science advances

Nature structural & molecular biology

Molecular microbiology

Technische Universität Braunschweig

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Technische Universität Braunschweig Apr 07 2014

Germany

Professor :: Molecular Cell Biology

Helmholtz-Zentrum für Infektionsforschung GmbH Apr 07 2014

Germany

Group Leader :: Department of Cell Biology

Publications

Klemens Rottner, Peter J Bieling
Illuminating cortactin structure and function at actin filament branches. Nature structural & molecular biology 31 (5) (2024)
Irshad S Sharafutdinov, Barbara Friedrich, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer
Cortactin: A major cellular target of viral, protozoal, and fungal pathogens. Molecular microbiology (2024)
Irshad S Sharafutdinov, Barbara Friedrich, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer
Cortactin: A major cellular target of viral, protozoal, and fungal pathogens. Molecular microbiology 122 (2) (2024)
Irshad S Sharafutdinov, Barbara Friedrich, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer
Cortactin: A major cellular target of viral, protozoal, and fungal pathogens. Molecular microbiology 122 (2) (2024)
Klemens Rottner, Peter J Bieling
Illuminating cortactin structure and function at actin filament branches. Nature structural & molecular biology (2024)
Klemens Rottner, Peter J Bieling
Illuminating cortactin structure and function at actin filament branches. Nature structural & molecular biology 31 (5) (2024)
Klemens Rottner, Peter J Bieling
Illuminating cortactin structure and function at actin filament branches. Nature structural & molecular biology 31 (5) (2024)
Florian Fäßler, Manjunath G Javoor, Julia Datler, Hermann Döring, Florian W Hofer, Georgi Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner, Florian K M Schur
ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning. Science advances 9 (3) (2023)
Florian Fäßler, Manjunath G Javoor, Julia Datler, Hermann Döring, Florian W Hofer, Georgi Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner, Florian K M Schur
ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning. Science advances 9 (3) (2023)
Christopher Lambert, Katharina Schmidt, Marius Karger, Marc Stadler, Theresia E B Stradal, Klemens Rottner
Cytochalasans and Their Impact on Actin Filament Remodeling. Biomolecules 13 (8) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Florian Fäßler, Manjunath G Javoor, Julia Datler, Hermann Döring, Florian W Hofer, Georgi Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner, Florian K M Schur
ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning. Science advances 9 (3) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Florian Fäßler, Manjunath G Javoor, Julia Datler, Hermann Döring, Florian W Hofer, Georgi Dimchev, Victor-Valentin Hodirnau, Jan Faix, Klemens Rottner, Florian K M Schur
ArpC5 isoforms regulate Arp2/3 complex-dependent protrusion through differential Ena/VASP positioning. Science advances 9 (3) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Thomas Pokrant, Jens Ingo Hein, Sarah Körber, Andrea Disanza, Andreas Pich, Giorgio Scita, Klemens Rottner, Jan Faix
Ena/VASP clustering at microspike tips involves lamellipodin but not I-BAR proteins, and absolutely requires unconventional myosin-X. Proceedings of the National Academy of Sciences of the United States of America 120 (2) (2023)
Frieda Kage, Hermann Döring, Magdalena Mietkowska, Matthias Schaks, Franziska Grüner, Stephanie Stahnke, Anika Steffen, Mathias Müsken, Theresia E B Stradal, Klemens Rottner
Lamellipodia-like actin networks in cells lacking WAVE regulatory complex. Journal of cell science 135 (15) (2022)
Irshad S Sharafutdinov, Jakob Knorr, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer
Cortactin: A universal host cytoskeletal target of Gram-negative and Gram-positive bacterial pathogens. Molecular microbiology (2022)
Bojian Ding, Sheng Yang, Matthias Schaks, Yijun Liu, Abbigale J Brown, Klemens Rottner, Saikat Chowdhury, Baoyu Chen
Structures reveal a key mechanism of WAVE regulatory complex activation by Rac1 GTPase. Nature communications 13 (1) (2022)
Klemens Rottner, Theresia E B Stradal
WASP stings into matrix to lead immune cell migration. The Journal of cell biology 221 (2) (2022)
Marco Kirchenwitz, Stephanie Stahnke, Silvia Prettin, Malgorzata Borowiak, Laura Menke, Christian Sieben, Carmen Birchmeier, Klemens Rottner, Theresia E B Stradal, Anika Steffen
SMER28 Attenuates PI3K/mTOR Signaling by Direct Inhibition of PI3K p110 Delta. Cells 11 (10) (2022)
Daniel Kummer, Tim Steinbacher, Sonja Thölmann, Mariel Flavia Schwietzer, Christian Hartmann, Simone Horenkamp, Sabrina Demuth, Swetha S D Peddibhotla, Frauke Brinkmann, Björn Kemper, Juergen Schnekenburger, Matthias Brandt, Timo Betz, Ivan Liashkovich, Ivan U Kouzel, Victor Shahin, Nathalie Corvaia, Klemens Rottner, Katsiaryna Tarbashevich, Erez Raz, Lilo Greune, M Alexander Schmidt, Volker Gerke, Klaus Ebnet
A JAM-A-tetraspanin-αvβ5 integrin complex regulates contact inhibition of locomotion. The Journal of cell biology 221 (4) (2022)
Sheng Yang, Yubo Tang, Yijun Liu, Abbigale J Brown, Matthias Schaks, Bojian Ding, Daniel A Kramer, Magdalena Mietkowska, Li Ding, Olga Alekhina, Daniel D Billadeau, Saikat Chowdhury, Junmei Wang, Klemens Rottner, Baoyu Chen
Arf GTPase activates the WAVE regulatory complex through a distinct binding site. Science advances 8 (50) (2022)
Sheng Yang, Yubo Tang, Yijun Liu, Abbigale J Brown, Matthias Schaks, Bojian Ding, Daniel A Kramer, Magdalena Mietkowska, Li Ding, Olga Alekhina, Daniel D Billadeau, Saikat Chowdhury, Junmei Wang, Klemens Rottner, Baoyu Chen
Arf GTPase activates the WAVE regulatory complex through a distinct binding site. Science advances 8 (50) (2022)
Elisabeth Salzer, Samaneh Zoghi, Máté G Kiss, Frieda Kage, Christina Rashkova, Stephanie Stahnke, Matthias Haimel, René Platzer, Michael Caldera, Rico Chandra Ardy, Birgit Hoeger, Jana Block, David Medgyesi, Celine Sin, Sepideh Shahkarami, Renate Kain, Vahid Ziaee, Peter Hammerl, Christoph Bock, J Formula See Text Rg Menche, Loïc Dupré, Johannes B Huppa, Michael Sixt, Alexis J Lomakin, Klemens Rottner, Christoph J Binder, Theresia E B Stradal, Nima Rezaei, Kaan Boztug
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science immunology 5 (49) (2022)
Jan Faix, Klemens Rottner
Ena/VASP proteins in cell edge protrusion, migration and adhesion. Journal of cell science 135 (6) (2022)
Amine Mehidi, Frieda Kage, Zeynep Karatas, Maureen Cercy, Matthias Schaks, Anna Polesskaya, Matthieu Sainlos, Alexis M Gautreau, Olivier Rossier, Klemens Rottner, Grégory Giannone
Forces generated by lamellipodial actin filament elongation regulate the WAVE complex during cell migration. Nature cell biology 23 (11) (2021)
Johanna Funk, Felipe Merino, Matthias Schaks, Klemens Rottner, Stefan Raunser, Peter J Bieling
A barbed end interference mechanism reveals how capping protein promotes nucleation in branched actin networks. Nature communications 12 (1) (2021)
Jonas Cornelius, Klemens Rottner, Martin Korte, Kristin Michaelsen-Preusse
Cortactin Contributes to Activity-Dependent Modulation of Spine Actin Dynamics and Spatial Memory Formation. Cells 10 (7) (2021)
Jakob Knorr, Irshad S Sharafutdinov, Florian Fiedler, Delara Soltan Esmaeili, Manfred Rohde, Klemens Rottner, Steffen Backert, Nicole Tegtmeyer
Cortactin Is Required for Efficient FAK, Src and Abl Tyrosine Kinase Activation and Phosphorylation of Helicobacter pylori CagA. International journal of molecular sciences 22 (11) (2021)
Nicole Tegtmeyer, Aileen Harrer, Klemens Rottner, Steffen Backert
Helicobacter pylori CagA Induces Cortactin Y-470 Phosphorylation-Dependent Gastric Epithelial Cell Scattering via Abl, Vav2 and Rac1 Activation. Cancers 13 (16) (2021)
Georgi Dimchev, Behnam Amiri, Ashley C Humphries, Matthias Schaks, Vanessa Dimchev, Theresia E B Stradal, Jan Faix, Matthias Krause, Michael Way, Martin Falcke, Klemens Rottner
Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formation. Journal of cell science 133 (7) (2020)
Chongqing Wang, Christopher Lambert, Maurice Hauser, Adrian Deuschmann, Carsten Zeilinger, Klemens Rottner, Theresia E B Stradal, Marc Stadler, Elizabeth J Skellam, Russell J Cox
Diversely Functionalised Cytochalasins through Mutasynthesis and Semi-Synthesis. Chemistry (Weinheim an der Bergstrasse, Germany) 26 (60) (2020)
Vasileios Papalazarou, Karthic Swaminathan, Farah Jaber-Hijazi, Heather Spence, Ines Lahmann, Colin Nixon, Manuel Salmeron-Sanchez, Hans-Henning Arnold, Klemens Rottner, Laura M Machesky
The Arp2/3 complex is crucial for colonisation of the mouse skin by melanoblasts. Development (Cambridge, England) 147 (22) (2020)
Julia Damiano-Guercio, Laëtitia Kurzawa, Jan Mueller, Georgi Dimchev, Matthias Schaks, Maria Nemethova, Thomas Pokrant, Stefan Brühmann, Joern Linkner, Laurent Blanchoin, Michael Sixt, Klemens Rottner, Jan Faix
Loss of Ena/VASP interferes with lamellipodium architecture, motility and integrin-dependent adhesion. eLife 9 (2020)
Shashi Prakash Singh, Peter A Thomason, Sergio Lilla, Matthias Schaks, Qing Tang, Bruce L Goode, Laura M Machesky, Klemens Rottner, Robert H Insall
Cell-substrate adhesion drives Scar/WAVE activation and phosphorylation by a Ste20-family kinase, which controls pseudopod lifetime. PLoS biology 18 (8) (2020)
Tom Kunschmann, Stefanie Puder, Tony Fischer, Anika Steffen, Klemens Rottner, Claudia Tanja Mierke
The Small GTPase Rac1 Increases Cell Surface Stiffness and Enhances 3D Migration Into Extracellular Matrices. Scientific reports 9 (1) (2019)
Matthias Schaks, Hermann Döring, Frieda Kage, Anika Steffen, Thomas Klünemann, Wulf Blankenfeldt, Theresia E B Stradal, Klemens Rottner
RhoG and Cdc42 can contribute to Rac-dependent lamellipodia formation through WAVE regulatory complex-binding. Small GTPases 12 (2) (2019)
Frieda Kage, Anika Steffen, Adolf Ellinger, Carmen Ranftler, Christian Gehre, Cord Brakebusch, Margit Pavelka, Theresia Stradal, Klemens Rottner
Author Correction: FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42. Scientific reports 9 (1) (2019)
Martha Velázquez-Avila, Juan Carlos Balandrán, Dalia Ramirez-Ramirez, Mirella Velázquez-Avila, Antonio Sandoval, Alfonso Felipe-López, Porfirio Nava, José Antonio Alvarado-Moreno, David Dozal, Jessica Lashkmin Prieto-Chávez, Matthias Schaks, Klemens Rottner, Elisa Dorantes-Acosta, Briceida López-Martínez, Michael Schnoor, Rosana Pelayo
High cortactin expression in B-cell acute lymphoblastic leukemia is associated with increased transendothelial migration and bone marrow relapse. Leukemia 33 (6) (2018)
Frieda Kage, Anika Steffen, Adolf Ellinger, Carmen Ranftler, Christian Gehre, Cord Brakebusch, Margit Pavelka, Theresia Stradal, Klemens Rottner
FMNL2 and -3 regulate Golgi architecture and anterograde transport downstream of Cdc42. Scientific reports 7 (1) (2017)
Ralph Thomas Böttcher, Maik Veelders, Pascaline Rombaut, Jan Faix, Marina Theodosiou, Theresia E B Stradal, Klemens Rottner, Roy Zent, Franz Herzog, Reinhard Fässler
Kindlin-2 recruits paxillin and Arp2/3 to promote membrane protrusions during initial cell spreading. The Journal of cell biology 216 (11) (2017)
Frieda Kage, Moritz Winterhoff, Vanessa Dimchev, Jan Mueller, Tobias Thalheim, Anika Freise, Stefan Brühmann, Jana Kollasser, Jennifer Block, Georgi Dimchev, Matthias Geyer, Hans-Joachim Schnittler, Cord Brakebusch, Theresia E B Stradal, Marie-France Carlier, Michael Sixt, Josef Käs, Jan Faix, Klemens Rottner
FMNL formins boost lamellipodial force generation. Nature communications 8 (2017)
Alexander Leithner, Alexander Eichner, Jan Müller, Anne Reversat, Markus Brown, Jan Schwarz, Jack Merrin, David J J de Gorter, Florian Schur, Jonathan Bayerl, Ingrid de Vries, Stefan Wieser, Robert Hauschild, Frank P L Lai, Markus Moser, Dontscho Kerjaschki, Klemens Rottner, J Victor Small, Theresia E B Stradal, Michael Sixt
Diversified actin protrusions promote environmental exploration but are dispensable for locomotion of leukocytes. Nature cell biology 18 (11) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Klemens Rottner