Johannes B Huppa

ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 33

Top Venues

Nature immunology

Nature communications

Vaccines

Science advances

Medical University of Vienna

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Medical University of Vienna Nov 02 2011

Austria

Professor :: Center for Pathophysiology, Infectiology and Immunology

Publications

Angelika Wagner, Erika Garner-Spitzer, Claudia Auer, Pia Gattinger, Ines Zwazl, René Platzer, Maria Orola-Taus, Peter Pichler, Fabian Amman, Andreas Bergthaler, Johannes B Huppa, Hannes Stockinger, Christoph C Zielinski, Rudolf Valenta, Michael Kundi, Ursula Wiedermann
Breakthrough Infections in SARS-CoV-2-Vaccinated Multiple Myeloma Patients Improve Cross-Protection against Omicron Variants. Vaccines 12 (5) (2024)
Jiri Eitler, Wiebke Rackwitz, Natalie Wotschel, Venugopal Gudipati, Nivedha Murali Shankar, Anastasia Sidorenkova, Johannes B Huppa, Paola Ortiz-Montero, Corinna Opitz, Stephan R Künzel, Susanne Michen, Achim Temme, Liliana Rodrigues Loureiro, Anja Feldmann, Michael Bachmann, Laurent Boissel, Hans Klingemann, Winfried S Wels, Torsten Tonn
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation. Journal for immunotherapy of cancer 12 (2) (2024)
Vanessa Mühlgrabner, Timo Peters, Rubí M-H Velasco Cárdenas, Benjamin Salzer, Janett Göhring, Angelika Plach, Maria Höhrhan, Iago Doel Perez, Vasco Dos Reis Gonçalves, Jesús Siller Farfán, Manfred Lehner, Hannes Stockinger, Wolfgang W A Schamel, Kilian Schober, Dirk H Busch, Michael Hudecek, Omer Dushek, Susana Minguet, René Platzer, Johannes B Huppa
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation. Science advances 10 (36) (2024)
Angelika Wagner, Erika Garner-Spitzer, Claudia Auer, Pia Gattinger, Ines Zwazl, René Platzer, Maria Orola-Taus, Peter Pichler, Fabian Amman, Andreas Bergthaler, Johannes B Huppa, Hannes Stockinger, Christoph C Zielinski, Rudolf Valenta, Michael Kundi, Ursula Wiedermann
Breakthrough Infections in SARS-CoV-2-Vaccinated Multiple Myeloma Patients Improve Cross-Protection against Omicron Variants. Vaccines 12 (5) (2024)
Vanessa Mühlgrabner, Timo Peters, Rubí M-H Velasco Cárdenas, Benjamin Salzer, Janett Göhring, Angelika Plach, Maria Höhrhan, Iago Doel Perez, Vasco Dos Reis Gonçalves, Jesús Siller Farfán, Manfred Lehner, Hannes Stockinger, Wolfgang W A Schamel, Kilian Schober, Dirk H Busch, Michael Hudecek, Omer Dushek, Susana Minguet, René Platzer, Johannes B Huppa
TCR/CD3-based synthetic antigen receptors (TCC) convey superior antigen sensitivity combined with high fidelity of activation. Science advances 10 (36) (2024)
Lukas Schrangl, Vanessa Mühlgrabner, René Platzer, Florian Kellner, Josephine Wieland, Reinhard Obst, Jose Luis Toca-Herrera, Johannes B Huppa, Gerhard J Schütz, Janett Göhring
Advanced Quantification of Receptor-Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy. Biomolecules 14 (8) (2024)
Janett Göhring, Janett Göhring, Florian Kellner, Johannes B Huppa, Gerhard J Schütz
Measurement of Forces Acting on Single T-Cell Receptors. Methods in molecular biology (Clifton, N.J.) 2800 (2024)
Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan
CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition. Nature communications 15 (1) (2024)
Jiri Eitler, Wiebke Rackwitz, Natalie Wotschel, Venugopal Gudipati, Nivedha Murali Shankar, Anastasia Sidorenkova, Johannes B Huppa, Paola Ortiz-Montero, Corinna Opitz, Stephan R Künzel, Susanne Michen, Achim Temme, Liliana Rodrigues Loureiro, Anja Feldmann, Michael Bachmann, Laurent Boissel, Hans Klingemann, Winfried S Wels, Torsten Tonn
CAR-mediated targeting of NK cells overcomes tumor immune escape caused by ICAM-1 downregulation. Journal for immunotherapy of cancer 12 (2) (2024)
Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan
CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition. Nature communications 15 (1) (2024)
Lukas Schrangl, Vanessa Mühlgrabner, René Platzer, Florian Kellner, Josephine Wieland, Reinhard Obst, Jose Luis Toca-Herrera, Johannes B Huppa, Gerhard J Schütz, Janett Göhring
Advanced Quantification of Receptor-Ligand Interaction Lifetimes via Single-Molecule FRET Microscopy. Biomolecules 14 (8) (2024)
Irene Andreu-Saumell, Alba Rodriguez-Garcia, Vanessa Mühlgrabner, Marta Gimenez-Alejandre, Berta Marzal, Joan Castellsagué, Fara Brasó-Maristany, Hugo Calderon, Laura Angelats, Salut Colell, Mara Nuding, Marta Soria-Castellano, Paula Barbao, Aleix Prat, Alvaro Urbano-Ispizua, Johannes B Huppa, Sonia Guedan
CAR affinity modulates the sensitivity of CAR-T cells to PD-1/PD-L1-mediated inhibition. Nature communications 15 (1) (2024)
René Platzer, Joschka Hellmeier, Janett Göhring, Iago Doel Perez, Philipp Schatzlmaier, Clara Bodner, Margarete Focke-Tejkl, Gerhard J Schütz, Eva Sevcsik, Hannes Stockinger, Mario Brameshuber, Johannes B Huppa
Monomeric agonist peptide/MHCII complexes activate T-cells in an autonomous fashion. EMBO reports (2023)
Johannes B Huppa, Gerhard J Schütz
T-cell antigen recognition: catch-as-catch-can or catch-22? The EMBO journal (2023)
Rubí M-H Velasco Cárdenas, Simon M Brandl, Ana Valeria Meléndez, Alexandra Emilia Schlaak, Annabelle Buschky, Timo Peters, Fabian Beier, Bryan Serrels, Sanaz Taromi, Katrin Raute, Simon Hauri, Matthias Gstaiger, Silke Lassmann, Johannes B Huppa, Melanie Börries, Geoffroy Andrieux, Bertram Bengsch, Wolfgang W A Schamel, Susana Minguet
Harnessing CD3 diversity to optimize CAR T cells. Nature immunology (2023)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Elisabeth Salzer, Samaneh Zoghi, Máté G Kiss, Frieda Kage, Christina Rashkova, Stephanie Stahnke, Matthias Haimel, René Platzer, Michael Caldera, Rico Chandra Ardy, Birgit Hoeger, Jana Block, David Medgyesi, Celine Sin, Sepideh Shahkarami, Renate Kain, Vahid Ziaee, Peter Hammerl, Christoph Bock, J Formula See Text Rg Menche, Loïc Dupré, Johannes B Huppa, Michael Sixt, Alexis J Lomakin, Klemens Rottner, Christoph J Binder, Theresia E B Stradal, Nima Rezaei, Kaan Boztug
The cytoskeletal regulator HEM1 governs B cell development and prevents autoimmunity. Science immunology 5 (49) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Veronika Horkova, Ales Drobek, Darina Paprckova, Veronika Niederlova, Avishek Prasai, Valeria Uleri, Daniela Glatzova, Markus Kraller, Michaela Cesnekova, Sarka Janusova, Eva Salyova, Oksana Tsyklauri, Theresa A Kadlecek, Katerina Krizova, René Platzer, Kilian Schober, Dirk H Busch, Arthur Weiss, Johannes B Huppa, Ondrej Stepanek
Unique roles of co-receptor-bound LCK in helper and cytotoxic T cells. Nature immunology 24 (1) (2022)
Janett Göhring, Florian Kellner, Lukas Schrangl, René Platzer, Enrico Klotzsch, Hannes Stockinger, Johannes B Huppa, Gerhard J Schütz
Temporal analysis of T-cell receptor-imposed forces via quantitative single molecule FRET measurements. Nature communications 12 (1) (2021)
Joschka Hellmeier, Rene Platzer, Alexandra S Eklund, Thomas Schlichthaerle, Andreas Karner, Viktoria Motsch, Magdalena C Schneider, Elke Kurz, Victor Bamieh, Mario Brameshuber, Johannes Preiner, Ralf Jungmann, Hannes Stockinger, Gerhard J Schütz, Johannes B Huppa, Eva Sevcsik
DNA origami demonstrate the unique stimulatory power of single pMHCs as T cell antigens. Proceedings of the National Academy of Sciences of the United States of America 118 (4) (2021)
Benedikt Agerer, Maximilian Koblischke, Venugopal Gudipati, Luis Fernando Montaño-Gutierrez, Mark Smyth, Alexandra M Popa, Jakob-Wendelin Genger, Lukas Endler, David M Florian, Vanessa Mühlgrabner, Marianne Graninger, Stephan W Aberle, Anna-Maria Husa, Lisa Ellen Shaw, Alexander Lercher, Pia Gattinger, Ricard Torralba-Gombau, Doris Trapin, Thomas Penz, Daniele Barreca, Ingrid Fae, Sabine Wenda, Marianna Theresia Traugott, Gernot Walder, Winfried F Pickl, Volker Thiel, Franz Allerberger, Hannes Stockinger, Elisabeth Puchhammer-Stöckl, Wolfgang Weninger, Gottfried F Fischer, Wolfgang Paul Hoepler, Erich Pawelka, Alexander Zoufaly, Rudolf Valenta, Christoph Bock, Wolfgang Paster, René Geyeregger, Matthias Farlik, Florian Halbritter, Johannes B Huppa, Judith H Aberle, Andreas Bergthaler
SARS-CoV-2 mutations in MHC-I-restricted epitopes evade CD8+ T cell responses. Science immunology 6 (57) (2021)
Venugopal Gudipati, Julian Rydzek, Iago Doel Perez, Vasco Dos Reis Gonçalves, Lydia Scharf, Sebastian Königsberger, Elisabeth Lobner, Renate Kunert, Hermann Einsele, Hannes Stockinger, Michael Hudecek, Johannes B Huppa
Inefficient CAR-proximal signaling blunts antigen sensitivity. Nature immunology 21 (8) (2020)
Benjamin Salzer, Christina M Schueller, Charlotte U Brey, Timo Peters, Michael A Schoeber, Boris Kovacic, Michelle Claudine Buri, Elisabeth Lobner, Omer Dushek, Johannes B Huppa, Christian Obinger, Eva Maria Putz, Wolfgang Holter, Michael W Traxlmayr, Manfred Lehner
Engineering AvidCARs for combinatorial antigen recognition and reversible control of CAR function. Nature communications 11 (1) (2020)
René Platzer, Benedikt K Rossboth, Magdalena C Schneider, Eva Sevcsik, Florian Baumgart, Hannes Stockinger, Gerhard J Schütz, Johannes B Huppa, Mario Brameshuber
Unscrambling fluorophore blinking for comprehensive cluster detection via photoactivated localization microscopy. Nature communications 11 (1) (2020)
Annika De Sousa Linhares, Florian Kellner, Sabrina Jutz, Gerhard J Zlabinger, Hans-Joachim Gabius, Johannes B Huppa, Judith Leitner, Peter Steinberger
TIM-3 and CEACAM1 do not interact in cis and in trans. European journal of immunology 50 (8) (2020)
Mario Brameshuber, Florian Kellner, Benedikt K Rossboth, Haisen Ta, Kevin Alge, Eva Sevcsik, Janett Göhring, Markus Axmann, Florian Baumgart, Nicholas R J Gascoigne, Simon J Davis, Hannes Stockinger, Gerhard J Schütz, Johannes B Huppa
Monomeric TCRs drive T cell antigen recognition. Nature immunology 19 (5) (2018)
Benedikt K Rossboth, Andreas M Arnold, Haisen Ta, René Platzer, Florian Kellner, Johannes B Huppa, Mario Brameshuber, Florian Baumgart, Gerhard J Schütz
TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells. Nature immunology 19 (8) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Johannes B Huppa