Laurent Meijer

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2017-2024
Publications (10 Years): 26

Top Venues

Science translational medicine

Journal of medicinal chemistry

International journal of molecular sciences

Molecules (Basel, Switzerland)

Perha Pharmaceuticals

Université Lille 1 (MSC)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Perha Pharmaceuticals May 02 2019

France

Chairman & CSO :: 29

Station Biologique de Roscoff

France

Directeur de Recherches de Classe Exceptionnelle :: CNRS

ManRos Therapeutics (France) Jun 22 2007

France

Chairman & CSO :: 29

Station Biologique de Roscoff

France

Director of CNRS :: USR-3151 “Protein Phosphorylation & Human Disease”.

Station Biologique de Roscoff

France

Director of CNRS :: UPS-2682 “Molécules & Cibles Thérapeutiques”

Station Biologique de Roscoff

France

Directeur de Recherches 1ere classe :: CNRS

Station Biologique de Roscoff

France

Directeur de Recherches 2eme classe :: CNRS

Education History

Université Lille 1

France

MSC :: Structural & Metabolic Biochemistry - Cell Biology & Physiology

Publications

Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Mattias F Lindberg, Emmanuel Deau, Jonas Arfwedson, Nicolas George, Pascal George, Patricia Alfonso, Ana Corrionero, Laurent Meijer
Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases. Journal of medicinal chemistry 66 (6) (2023)
Emmanuel Deau, Mattias F Lindberg, Frédéric Miege, Didier Roche, Nicolas George, Pascal George, Andreas Krämer, Stefan Knapp, Laurent Meijer
Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B. Journal of medicinal chemistry (2023)
Mattias F Lindberg, Emmanuel Deau, Frédéric Miege, Marie Greverie, Didier Roche, Nicolas George, Pascal George, Laura Merlet, Julie Gavard, Sander J T Brugman, Edwin Aret, Paul Tinnemans, René de Gelder, Jan Sadownik, Eva Verhofstad, Dennis Sleegers, Sara Santangelo, Julien Dairou, Álvaro Fernandez-Blanco, Mara Dierssen, Andreas Krämer, Stefan Knapp, Laurent Meijer
Chemical, Biochemical, Cellular, and Physiological Characterization of Leucettinib-21, a Down Syndrome and Alzheimer's Disease Drug Candidate. Journal of medicinal chemistry (2023)
Mattias F Lindberg, Emmanuel Deau, Jonas Arfwedson, Nicolas George, Pascal George, Patricia Alfonso, Ana Corrionero, Laurent Meijer
Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases. Journal of medicinal chemistry (2023)
Mattias F Lindberg, Emmanuel Deau, Jonas Arfwedson, Nicolas George, Pascal George, Patricia Alfonso, Ana Corrionero, Laurent Meijer
Comparative Efficacy and Selectivity of Pharmacological Inhibitors of DYRK and CLK Protein Kinases. Journal of medicinal chemistry 66 (6) (2023)
Mattias F Lindberg, Laurent Meijer
Dual-Specificity, Tyrosine Phosphorylation-Regulated Kinases (DYRKs) and cdc2-Like Kinases (CLKs) in Human Disease, an Overview. International journal of molecular sciences 22 (11) (2021)
Amriti R Lulla, Said Akli, Cansu Karakas, Min Jin Ha, Natalie W Fowlkes, Yoshitsugu Mitani, Tuyen Bui, Jing Wang, Xiayu Rao, Kelly K Hunt, Laurent Meijer, Adel K El-Naggar, Khandan Keyomarsi
LMW cyclin E and its novel catalytic partner CDK5 are therapeutic targets and prognostic biomarkers in salivary gland cancers. Oncogenesis 10 (5) (2021)
Tania Tahtouh, Emilie Durieu, Benoît Villiers, Céline Bruyère, Thu Lan Nguyen, Xavier Fant, Kwang H Ahn, Leepakshi Khurana, Emmanuel Deau, Mattias F Lindberg, Elodie Sévère, Frédéric Miege, Didier Roche, Emmanuelle Limanton, Jean-Martial L'Helgoual'ch, Guillaume Burgy, Solène Guiheneuf, Yann Herault, Debra A Kendall, François Carreaux, Jean-Pierre Bazureau, Laurent Meijer
Structure-Activity Relationship in the Leucettine Family of Kinase Inhibitors. Journal of medicinal chemistry 65 (2) (2021)
Svenja Koslowski, Camille Latapy, Pierrïck Auvray, Marc Blondel, Laurent Meijer
An Overview of In Vivo and In Vitro Models for Autosomal Dominant Polycystic Kidney Disease: A Journey from 3D-Cysts to Mini-Pigs. International journal of molecular sciences 21 (12) (2020)
Cyril Leven, Sacha Schutz, Marie-Pierre Audrezet, Emmanuel Nowak, Laurent Meijer, Tristan Montier
Non-Linear Pharmacokinetics of Oral Roscovitine (Seliciclib) in Cystic Fibrosis Patients Chronically Infected with Pseudomonas aeruginosa: A Study on Population Pharmacokinetics with Monte Carlo Simulations. Pharmaceutics 12 (11) (2020)
Christian Lechner, Maren Flaßhoff, Hannes Falke, Lutz Preu, Nadége Loaëc, Laurent Meijer, Stefan Knapp, Apirat Chaikuad, Conrad Kunick
[b]-Annulated Halogen-Substituted Indoles as Potential DYRK1A Inhibitors. Molecules (Basel, Switzerland) 24 (22) (2019)
Germana Esposito, Linh H Mai, Arlette Longeon, Alfonso Mangoni, Emilie Durieu, Laurent Meijer, Rob Van Soest, Valeria Costantino, Marie-Lise Bourguet-Kondracki
A Collection of Bioactive Nitrogen-Containing Molecules from the Marine Sponge Acanthostrongylophora ingens. Marine drugs 17 (8) (2019)
Virginie Vauthier, Amel Ben Saad, Jonathan Elie, Nassima Oumata, Anne-Marie Durand-Schneider, Alix Bruneau, Jean-Louis Delaunay, Chantal Housset, Tounsia Aït-Slimane, Laurent Meijer, Thomas Falguières
Structural analogues of roscovitine rescue the intracellular traffic and the function of ER-retained ABCB4 variants in cell models. Scientific reports 9 (1) (2019)
Katy Billot, Charlène Coquil, Benoit Villiers, Béatrice Josselin-Foll, Nathalie Desban, Claire Delehouzé, Nassima Oumata, Yannick Le Meur, Alessandra Boletta, Thomas Weimbs, Melanie Grosch, Ralph Witzgall, Sophie Saunier, Evelyne Fischer, Marco Pontoglio, Alain Fautrel, Michal Mrug, Darren Wallace, Pamela V Tran, Marie Trudel, Nikolay Bukanov, Oxana Ibraghimov-Beskrovnaya, Laurent Meijer
Casein kinase 1ε and 1α as novel players in polycystic kidney disease and mechanistic targets for (R)-roscovitine and (S)-CR8. American journal of physiology. Renal physiology 315 (1) (2018)
Rosanna Meine, Walter Becker, Hannes Falke, Lutz Preu, Nadège Loaëc, Laurent Meijer, Conrad Kunick
Indole-3-Carbonitriles as DYRK1A Inhibitors by Fragment-Based Drug Design. Molecules (Basel, Switzerland) 23 (2) (2018)
Thu Lan Nguyen, Arnaud Duchon, Antigoni Manousopoulou, Nadège Loaëc, Benoît Villiers, Guillaume Pani, Meltem Karatas, Anna E Mechling, Laura-Adela Harsan, Emmanuelle Limanton, Jean-Pierre Bazureau, François Carreaux, Spiros D D Garbis, Laurent Meijer, Yann Hérault
Correction of cognitive deficits in mouse models of Down syndrome by a pharmacological inhibitor of DYRK1A. Disease models & mechanisms 11 (9) (2018)
Florence Couly, Marine Harari, Carole Dubouilh-Benard, Laetitia Bailly, Emilie Petit, Julien Diharce, Pascal Bonnet, Laurent Meijer, Corinne Fruit, Thierry Besson
Development of Kinase Inhibitors via Metal-Catalyzed C⁻H Arylation of 8-Alkyl-thiazolo[5,4-f]-quinazolin-9-ones Designed by Fragment-Growing Studies. Molecules (Basel, Switzerland) 23 (9) (2018)
Nadège Loaëc, Eletta Attanasio, Benoît Villiers, Emilie Durieu, Tania Tahtouh, Morgane Cam, Rohan A Davis, Aline Alencar, Mélanie Roué, Marie-Lise Bourguet-Kondracki, Peter Proksch, Emmanuelle Limanton, Solène Guiheneuf, François Carreaux, Jean-Pierre Bazureau, Michelle Klautau, Laurent Meijer
Marine-Derived 2-Aminoimidazolone Alkaloids. Leucettamine B-Related Polyandrocarpamines Inhibit Mammalian and Protozoan DYRK & CLK Kinases. Marine drugs 15 (10) (2017)
Vassilios Myrianthopoulos, Olivier Lozach, Danae Zareifi, Leonidas Alexopoulos, Laurent Meijer, Vassilis G Gorgoulis, Emmanuel Mikros
Combined Virtual and Experimental Screening for CK1 Inhibitors Identifies a Modulator of p53 and Reveals Important Aspects of in Silico Screening Performance. International journal of molecular sciences 18 (10) (2017)

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Publication Activity (10 Years)

Top Topics

Top Venues

Laurent Meijer