Victor L J Tybulewicz (Victor Lj Tybulewicz, Victor Tybulewicz)

ORCID

Publication Activity (10 Years)

Years Active: 2013-2024
Publications (10 Years): 40

Top Venues

The Journal of experimental medicine

Development (Cambridge, England)

Science translational medicine

eLife

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Cambridge Sep 20 1981 - Sep 20 1984

United Kingdom

PHD :: MRC Laboratory of Molecular Biology

Imperial College London Sep 20 1978 - Jun 30 1981

United Kingdom

BSC :: Biochemistry

Publications

Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Eva Lana-Elola, Rifdat Aoidi, Miriam Llorian Sopena, Dorota Gibbins, Callan Buechsenschuetz, Claudio Bussi, Helen R Flynn, Tegan Gilmore, Sheona Watson-Scales, Marie H Hansen, Darryl A Hayward, Ok-Ryul Song, Véronique Brault, Yann Hérault, Emmanuel Deau, Laurent Meijer, Ambrosius P Snijders, Maximiliano G Gutierrez, Elizabeth M C Fisher, Victor L J Tybulewicz
Increased dosage of DYRK1A leads to congenital heart defects in a mouse model of Down syndrome. Science translational medicine 16 (731) (2024)
Darryl A Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O'May, Leonard L de Boer, Richard Mitter, Robert Köchl, Jens V Stein, Victor L J Tybulewicz
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice. The Journal of experimental medicine 220 (3) (2023)
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewicz
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England) 150 (8) (2023)
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewicz
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England) 150 (8) (2023)
Leonard L de Boer, Lesley Vanes, Serena Melgrati, Joshua Biggs O'May, Darryl Hayward, Paul C Driscoll, Jason Day, Alexander Griffiths, Renata Magueta, Alexander P Morrell, James I MacRae, Robert Köchl, Victor L J Tybulewicz
T cell migration requires ion and water influx to regulate actin polymerization. Nature communications 14 (1) (2023)
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewicz
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England) 150 (8) (2023)
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewicz
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England) 150 (8) (2023)
Darryl A Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O'May, Leonard L de Boer, Richard Mitter, Robert Köchl, Jens V Stein, Victor L J Tybulewicz
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice. The Journal of experimental medicine 220 (3) (2023)
Darryl A Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O'May, Leonard L de Boer, Richard Mitter, Robert Köchl, Jens V Stein, Victor L J Tybulewicz
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice. The Journal of experimental medicine 220 (3) (2023)
Darryl A Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O'May, Leonard L de Boer, Richard Mitter, Robert Köchl, Jens V Stein, Victor L J Tybulewicz
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice. The Journal of experimental medicine 220 (3) (2023)
Darryl A Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O'May, Leonard L de Boer, Richard Mitter, Robert Köchl, Jens V Stein, Victor L J Tybulewicz
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice. The Journal of experimental medicine 220 (3) (2023)
Darryl A Hayward, Lesley Vanes, Stefanie Wissmann, Sujana Sivapatham, Harald Hartweger, Joshua Biggs O'May, Leonard L de Boer, Richard Mitter, Robert Köchl, Jens V Stein, Victor L J Tybulewicz
B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice. The Journal of experimental medicine 220 (3) (2023)
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewicz
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England) 150 (8) (2023)
Yushi Redhead, Dorota Gibbins, Eva Lana-Elola, Sheona Watson-Scales, Lisa Dobson, Matthias Krause, Karen J Liu, Elizabeth M C Fisher, Jeremy B A Green, Victor L J Tybulewicz
Craniofacial dysmorphology in Down syndrome is caused by increased dosage of Dyrk1a and at least three other genes. Development (Cambridge, England) 150 (8) (2023)
Paige S Mumford, Justin Tosh, Silvia Anderle, Eleni Gkanatsiou Wikberg, Gloria Lau, Sue Noy, Karen Cleverley, Takashi Saito, Takaomi C Saido, Eugene Yu, Gunnar Brinkmalm, Erik Portelius, Kaj Blennow, Henrik Zetterberg, Victor L J Tybulewicz, Elizabeth M C Fisher, Frances K Wiseman
Genetic Mapping of APP and Amyloid-β Biology Modulation by Trisomy 21. The Journal of neuroscience : the official journal of the Society for Neuroscience 42 (33) (2022)
Emilie J Cosway, Andrea J White, Sonia M Parnell, Edina Schweighoffer, Helen E Jolin, Andrea Bacon, Hans-Reimer Rodewald, Victor L J Tybulewicz, Andrew N J McKenzie, William E Jenkinson, Graham Anderson
Eosinophils are an essential element of a type 2 immune axis that controls thymus regeneration. Science immunology 7 (69) (2022)
Yang Zhang, Laura Garcia-Ibanez, Carolin Ulbricht, Laurence S C Lok, Jeremy A Pike, Jennifer Mueller-Winkler, Thomas W Dennison, John R Ferdinand, Cameron J M Burnett, Juan Carlos Yam-Puc, Lingling Zhang, Raul Maqueda Alfaro, Yousuke Takahama, Izumi Ohigashi, Geoffrey Brown, Tomohiro Kurosaki, Victor L J Tybulewicz, Antal Rot, Anja E Hauser, Menna R Clatworthy, Kai-Michael Toellner
Recycling of memory B cells between germinal center and lymph node subcapsular sinus supports affinity maturation to antigenic drift. Nature communications 13 (1) (2022)
Nicolas Toussaint, Yushi Redhead, Marta Vidal-GARCíA, Lucas D Lo Vercio, Wei Liu, Elizabeth M C Fisher, Benedikt Hallgrimsson, Victor L J Tybulewicz, Julia A Schnabel, Jeremy B A Green
A landmark-free morphometrics pipeline for high-resolution phenotyping: application to a mouse model of Down syndrome. Development (Cambridge, England) 148 (18) (2021)
Jacinta I Kalisch-Smith, Nikita Ved, Dorota Szumska, Jacob E Munro, Michael Troup, Shelley E Harris, Helena Rodriguez-Caro, Aimée Jacquemot, Jack J J J Miller, Eleanor M Stuart, Magda Wolna, Emily Hardman, Fabrice Prin, Eva Lana-Elola, Rifdat Aoidi, Elizabeth M C Fisher, Victor L J Tybulewicz, Timothy J Mohun, Samira Lakhal-Littleton, Sarah De Val, Eleni Giannoulatou, Duncan Burnaby Sparrow
Maternal iron deficiency perturbs embryonic cardiovascular development in mice. Nature communications 12 (1) (2021)
Eva Lana-Elola, Heather Cater, Sheona Watson-Scales, Simon Greenaway, Jennifer Müller-Winkler, Dorota Gibbins, Mihaela Nemes, Amy Slender, Tertius Hough, Piia Keskivali-Bond, Cheryl L Scudamore, Eleanor Herbert, Gareth T Banks, Helene Mobbs, Tara Canonica, Justin Tosh, Suzanna Noy, Miriam Llorian, Patrick M Nolan, Julian L Griffin, Mark Good, Michelle Simon, Ann-Marie Mallon, Sara Wells, Elizabeth M C Fisher, Victor L J Tybulewicz
Comprehensive phenotypic analysis of the Dp1Tyb mouse strain reveals a broad range of Down syndrome-related phenotypes. Disease models & mechanisms 14 (10) (2021)
Lindsey Mayes-Hopfinger, Aura Enache, Jian Xie, Chou-Long Huang, Robert Köchl, Victor L J Tybulewicz, Teresa Fernandes-Alnemri, Emad S Alnemri
Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis. Nature communications 12 (1) (2021)
Eva Lana-Elola, Sheona Watson-Scales, Amy Slender, Dorota Gibbins, Alexandrine Martineau, Charlotte Douglas, Timothy Mohun, Elizabeth M C Fisher, Victor L J Tybulewicz
Correction: Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. eLife 9 (2020)
Robert Köchl, Lesley Vanes, Miriam Llorian Sopena, Probir Chakravarty, Harald Hartweger, Kathryn Fountain, Andrea White, Jennifer Cowan, Graham Anderson, Victor L J Tybulewicz
Critical role of WNK1 in MYC-dependent early mouse thymocyte development. eLife 9 (2020)
Teresa Rayon, Despina Stamataki, Ruben Perez-Carrasco, Lorena Garcia-Perez, Christopher Barrington, Manuela Melchionda, Katherine Exelby, Jorge Lazaro, Victor L J Tybulewicz, Elizabeth M C Fisher, James Briscoe
Species-specific pace of development is associated with differences in protein stability. Science (New York, N.Y.) 369 (6510) (2020)
Helena Ahlfors, Nneka Anyanwu, Edvinas Pakanavicius, Natalia Dinischiotu, Eva Lana-Elola, Sheona Watson-Scales, Justin Tosh, Frances K Wiseman, James Briscoe, Karen Page, Elizabeth M C Fisher, Victor L J Tybulewicz
Gene expression dysregulation domains are not a specific feature of Down syndrome. Nature communications 10 (1) (2019)
Simone Grannò, Jonathon Nixon-Abell, Daniel C Berwick, Justin Tosh, George Heaton, Sultan Almudimeegh, Zenisha Nagda, Jean-Christophe Rain, Manuela Zanda, Vincent Plagnol, Victor L J Tybulewicz, Karen Cleverley, Frances K Wiseman, Elizabeth M C Fisher, Kirsten Harvey
Downregulated Wnt/β-catenin signalling in the Down syndrome hippocampus. Scientific reports 9 (1) (2019)
Sheona Watson-Scales, Bernadett Kalmar, Eva Lana-Elola, Dorota Gibbins, Federica La Russa, Frances Wiseman, Matthew Williamson, Rachele Saccon, Amy Slender, Anna Olerinyova, Radma Mahmood, Emma Nye, Heather Cater, Sara E Wells, Y Eugene Yu, David L H Bennett, Linda Greensmith, Elizabeth M C Fisher, Victor L J Tybulewicz
Analysis of motor dysfunction in Down Syndrome reveals motor neuron degeneration. PLoS genetics 14 (5) (2018)
Damián E Pérez-Mazliah, Peter J Gardner, Edina Schweighoffer, Sarah McLaughlin, Caroline Hosking, Irene Tumwine, Randall S Davis, Alexandre J Potocnik, Victor L J Tybulewicz, Jean Langhorne
Plasmodium-specific atypical memory B cells are short-lived activated B cells. eLife 7 (2018)
Yann Hérault, Jean Maurice Delabar, Elizabeth M C Fisher, Victor L J Tybulewicz, Eugene Yu, Véronique Brault
Rodent models in Down syndrome research: impact and future opportunities. Disease models & mechanisms 10 (10) (2018)
Edina Schweighoffer, Josquin Nys, Lesley Vanes, Nicholas Smithers, Victor L J Tybulewicz
TLR4 signals in B lymphocytes are transduced via the B cell antigen receptor and SYK. The Journal of experimental medicine 214 (5) (2017)
Eva Lana-Elola, Sheona Watson-Scales, Amy Slender, Dorota Gibbins, Alexandrine Martineau, Charlotte Douglas, Timothy Mohun, Elizabeth Mc Fisher, Victor L J Tybulewicz
Genetic dissection of Down syndrome-associated congenital heart defects using a new mouse mapping panel. eLife 5 (2016)
Robert Köchl, Flavian Thelen, Lesley Vanes, Tiago F Brazão, Kathryn Fountain, Jian Xie, Chou-Long Huang, Ruth Lyck, Jens V Stein, Victor L J Tybulewicz
WNK1 kinase balances T cell adhesion versus migration in vivo. Nature immunology 17 (9) (2016)
Jing Qiu, Jamie McQueen, Bilada Bilican, Owen Dando, Dario Magnani, Karolina Punovuori, Bhuvaneish T Selvaraj, Matthew Livesey, Ghazal Haghi, Samuel Heron, Karen Burr, Rickie Patani, Rinku Rajan, Olivia Sheppard, Peter C Kind, Thomas Ian Simpson, Victor L J Tybulewicz, David J A Wyllie, Elizabeth Mc Fisher, Sally Lowell, Siddharthan Chandran, Giles E Hardingham
Evidence for evolutionary divergence of activity-dependent gene expression in developing neurons. eLife 5 (2016)
Tiago F Brazão, Jethro S Johnson, Jennifer Müller, Andreas Heger, Chris Paul Ponting, Victor L J Tybulewicz
Long noncoding RNAs in B-cell development and activation. Blood 128 (7) (2016)
Jochen A Ackermann, Josquin Nys, Edina Schweighoffer, Scott McCleary, Nicholas Smithers, Victor L J Tybulewicz
Syk tyrosine kinase is critical for B cell antibody responses and memory B cell survival. Journal of immunology (Baltimore, Md. : 1950) 194 (10) (2015)
Hideki Hara, Kohsuke Tsuchiya, Ikuo Kawamura, Rendong Fang, Eduardo Hernandez-Cuellar, Yanna Shen, Junichiro Mizuguchi, Edina Schweighoffer, Victor L J Tybulewicz, Masao Mitsuyama
Phosphorylation of the adaptor ASC acts as a molecular switch that controls the formation of speck-like aggregates and inflammasome activity. Nature immunology 14 (12) (2013)

Victor L J Tybulewicz.css-eqlu8i{font-size:small;padding-left:4px;} (Victor Lj Tybulewicz, Victor Tybulewicz)

Publication Activity (10 Years)

Top Topics

Top Venues

Victor L J Tybulewicz (Victor Lj Tybulewicz, Victor Tybulewicz)