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Leilei Chen

Scopus Author ID ORCID

Publication Activity (10 Years)

Years Active: 2018-2023
Publications (10 Years): 15

Top Venues

Nature communications

Science advances

Scientific reports

Blood

National University Singapore Yong Loo Lin School of Medicine

University of Hong Kong (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

National University Singapore Yong Loo Lin School of Medicine Jun 1o 2014

Singapore

Assistant Professor :: Anatomy

Education History

University of Hong Kong Sep 1o 2006 - May 1o 2010

Hong Kong

PHD :: Clinical Oncology

Publications

Tin-Lok Wong, Jia-Jian Loh, Shixun Lu, Helen H N Yan, Hoi Cheong Siu, Ren Xi, Dessy Chan, Max J F Kam, Lei Zhou, Man Tong, John A Copland, Leilei Chen, Jing-Ping Yun, Suet Yi Leung, Stephianie Ma
ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer. Nature communications 14 (1) (2023)
Tin-Lok Wong, Jia-Jian Loh, Shixun Lu, Helen H N Yan, Hoi Cheong Siu, Ren Xi, Dessy Chan, Max J F Kam, Lei Zhou, Man Tong, John A Copland, Leilei Chen, Jing-Ping Yun, Suet Yi Leung, Stephianie Ma
ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer. Nature communications 14 (1) (2023)
Mingrui Guo, Hon Man Tim Chan, Qi-Ling Zhou, Omer An, Ying Li, Yangyang Song, Zi Hui Tan, Hui En Vanessa Ng, Philomina Sona Peramangalam, Zhi Qing Tan, Xinang Cao, Eisaku Iwanaga, Masao Matsuoka, Melissa Gaik-Ming Ooi, Wei-Ying Jen, Liang Piu Koh, Esther Chan, Lip Kun Tan, Yufen Goh, Wilson Wang, Bryan T H Koh, Ming Chun Chan, Melissa J Fullwood, Wee-Joo Chng, Motomi Osato, John Anto Pulikkan, Henry Yang, Leilei Chen, Daniel Geoffrey Tenen
Core binding factor fusion downregulation of ADAR2 RNA editing contributes to AML leukemogenesis. Blood (2023)
Tin-Lok Wong, Jia-Jian Loh, Shixun Lu, Helen H N Yan, Hoi Cheong Siu, Ren Xi, Dessy Chan, Max J F Kam, Lei Zhou, Man Tong, John A Copland, Leilei Chen, Jing-Ping Yun, Suet Yi Leung, Stephianie Ma
ADAR1-mediated RNA editing of SCD1 drives drug resistance and self-renewal in gastric cancer. Nature communications 14 (1) (2023)
Leilei Chen
A-to-I editing prevents self-RNA sensing. Nature reviews. Molecular cell biology (2022)
Haoqing Shen, Omer An, Xi Ren, Yangyang Song, Sze Jing Tang, Xin-Yu Ke, Jian Han, Daryl Jin Tai Tay, Vanessa Hui En Ng, Fernando Bellido Molias, Priyankaa Pitcheshwar, Ka Wai Leong, Ker Kan Tan, Henry Yang, Leilei Chen
ADARs act as potent regulators of circular transcriptome in cancer. Nature communications 13 (1) (2022)
Jian Han, Omer An, Xi Ren, Yangyang Song, Sze Jing Tang, Haoqing Shen, Xinyu Ke, Vanessa Hui En Ng, Daryl Jin Tai Tay, Hui Qing Tan, Dennis Kappei, Henry Yang, Leilei Chen
Multilayered control of splicing regulatory networks by DAP3 leads to widespread alternative splicing changes in cancer. Nature communications 13 (1) (2022)
Omer An, Yangyang Song, Xinyu Ke, Jimmy Bok-Yan So, Raghav Sundar, Henry Yang, Sun Young Rha, Ming Hui Lee, Su Ting Tay, Xuewen Ong, Angie Lay Keng Tan, Matthew Chau Hsien Ng, Erwin Tantoso, Leilei Chen, Patrick Tan, Wei Peng Yong, null null
"3G" Trial: An RNA Editing Signature to Guide Gastric Cancer Chemotherapy. Cancer research 81 (10) (2021)
Junsu Kwon, Yanjing V Liu, Chong Gao, Mahmoud Adel Bassal, Adrianna I Jones, Junyu Yang, Zhiyuan Chen, Ying Li, Henry Yang, Leilei Chen, Annalisa Di Ruscio, Yvonne Tay, Li Chai, Daniel Geoffrey Tenen
Pseudogene-mediated DNA demethylation leads to oncogene activation. Science advances 7 (40) (2021)
Xin-Yu Ke, Ye Chen, Valarie Yu-Yan Tham, Ruby Yu-Tong Lin, Pushkar Dakle, Kassoum Nacro, Mark Edward Puhaindran, Peter Houghton, Angela Pang, Victor Kwanmin Lee, Ling-Wen Ding, Sigal Gery, Jeffrey Hill, Leilei Chen, Liang Xu, H Phillip Koeffler
MNK1 and MNK2 enforce expression of E2F1, FOXM1, and WEE1 to drive soft tissue sarcoma. Oncogene 40 (10) (2021)
Jian Han, Omer An, HuiQi Hong, Tim Hon Man Chan, Yangyang Song, Haoqing Shen, Sze Jing Tang, Jaymie Siqi Lin, Vanessa Hui En Ng, Daryl Jin Tai Tay, Fernando Bellido Molias, Priyankaa Pitcheshwar, Hui Qing Tan, Henry Yang, Leilei Chen
Suppression of adenosine-to-inosine (A-to-I) RNA editome by death associated protein 3 (DAP3) promotes cancer progression. Science advances 6 (25) (2020)
Pui Yan Yeung, Jieyu Zhao, Eugene Yui-Ching Chow, Xi Mou, HuiQi Hong, Leilei Chen, Ting-Fung Chan, Chun Kit Kwok
Author Correction: Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing. Scientific reports 10 (1) (2020)
Sze Jing Tang, Haoqing Shen, Omer An, HuiQi Hong, Jia Li, Yangyang Song, Jian Han, Daryl Jin Tai Tay, Vanessa Hui En Ng, Fernando Bellido Molias, Ka Wai Leong, Priyankaa Pitcheshwar, Henry Yang, Leilei Chen
Cis- and trans-regulations of pre-mRNA splicing by RNA editing enzymes influence cancer development. Nature communications 11 (1) (2020)
Pui Yan Yeung, Jieyu Zhao, Eugene Yui-Ching Chow, Xi Mou, HuiQi Hong, Leilei Chen, Ting-Fung Chan, Chun Kit Kwok
Systematic evaluation and optimization of the experimental steps in RNA G-quadruplex structure sequencing. Scientific reports 9 (1) (2019)
Phaik Ju Teoh, Omer An, Tae-Hoon Chung, Jing Yuan Chooi, Sabrina H M Toh, Shuangyi Fan, Wilson Wang, Bryan T H Koh, Melissa Jane Fullwood, Melissa Gaik-Ming Ooi, Sanjay de Mel, Cinnie Y Soekojo, Leilei Chen, Siok Bian Ng, Henry Yang, Wee-Joo Chng
Aberrant hyperediting of the myeloma transcriptome by ADAR1 confers oncogenicity and is a marker of poor prognosis. Blood 132 (12) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Leilei Chen