David M Virshup (David Virshup, D M Virshup)

Scopus Author ID Loop profile ORCID

Publication Activity (10 Years)

Years Active: 2014-2024
Publications (10 Years): 31

Top Venues

Proceedings of the National Academy of Sciences of the United States of America

Science advances

bioRxiv : the preprint server for biology

Oncogene

Duke-NUS Graduate Medical School

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Duke-NUS Graduate Medical School

Singapore

Professor, Program Director :: Program in Cancer and Stem Cell Biology

Duke University School of Medicine

United States

Professor :: Pediatrics

Huntsman Cancer Institute

United States

Investigator :: Oncological Sciences

University of Utah

United States

Professor :: Pediatrics

Johns Hopkins Hospital and Health System

United States

Clinical and Research Training :: Pediatrics

Publications

Zheng Zhong, David M Virshup
Recurrent mutations in tumor suppressor FBXW7 bypass Wnt/β-catenin addiction in cancer. Science advances 10 (14) (2024)
Zheng Zhong, David M Virshup
Recurrent mutations in tumor suppressor FBXW7 bypass Wnt/β-catenin addiction in cancer. Science advances 10 (14) (2024)
Rachel L Harold, Nikhil Kumar Tulsian, Rajesh Narasimamurthy, Noelle Yaitanes, Maria G Ayala Hernandez, Hsiau-Wei Lee, Priya Crosby, Sarvind M Tripathi, David M Virshup, Carrie L Partch
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1. bioRxiv : the preprint server for biology (2024)
Zheng Zhong, David M Virshup
Recurrent mutations in tumor suppressor FBXW7 bypass Wnt/β-catenin addiction in cancer. Science advances 10 (14) (2024)
Rachel L Harold, Nikhil Kumar Tulsian, Rajesh Narasimamurthy, Noelle Yaitanes, Maria G Ayala Hernandez, Hsiau-Wei Lee, Priya Crosby, Sarvind M Tripathi, David M Virshup, Carrie L Partch
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1. bioRxiv : the preprint server for biology (2024)
Rachel L Harold, Nikhil Kumar Tulsian, Rajesh Narasimamurthy, Noelle Yaitanes, Maria G Ayala Hernandez, Hsiau-Wei Lee, Priya Crosby, Sarvind M Tripathi, David M Virshup, Carrie L Partch
Isoform-specific C-terminal phosphorylation drives autoinhibition of Casein Kinase 1. bioRxiv : the preprint server for biology (2024)
Yi Fei Lee, Leilei Chen, Valerie Chew, Edward Kai-Hua Chow, Lih-Wen Deng, Walter Hunziker, Ann Siew Gek Lee, Geraldine Leong, Joanne Ngeow Yuen Yie, Shazib Pervaiz, Kanaga Sabapathy, Anders Jacobsen Skanderup, Raghav Sundar, Yvonne Tay, David M Virshup, Sunny-Hei Wong, Vinay Tergaonkar, Wai Leong Tam
Pushing the Frontiers of Cancer Research: Highlights from the Frontiers in Cancer Science Conference 2023. Cancer research 84 (8) (2024)
Jia Yu, David M Virshup
Functional regulation of Wnt protein through post-translational modifications. Biochemical Society transactions (2022)
Amanpreet Kaur, Jun Yi Stanley Lim, Sugunavathi Sepramaniam, Siddhi Patnaik, Nathan Harmston, May Ann Lee, Enrico Petretto, David M Virshup, Babita Madan
WNT inhibition creates a BRCA-like state in Wnt-addicted cancer. EMBO molecular medicine 13 (4) (2021)
Lucy Brunt, Gediminas Greicius, Sally Rogers, Benjamin D Evans, David M Virshup, Kyle C A Wedgwood, Steffen Scholpp
Vangl2 promotes the formation of long cytonemes to enable distant Wnt/β-catenin signaling. Nature communications 12 (1) (2021)
Zheng Zhong, Jia Yu, David M Virshup, Babita Madan
Wnts and the hallmarks of cancer. Cancer metastasis reviews 39 (3) (2021)
Jia Yu, Pei Ju Liao, Weijun Xu, Julie R Jones, David B Everman, Heather Flanagan-Steet, Thomas H Keller, David M Virshup
Structural model of PORCN illuminates disease-associated variants and drug binding sites. Journal of cell science (2021)
Mariano F Zacarias-Fluck, Toni Jauset, Sandra Martínez-Martín, Jastrinjan Kaur, Sílvia Casacuberta-Serra, Daniel Massó-Vallés, Erika Serrano Del Pozo, Génesis Martín-Fernández, Íñigo González-Larreategui, Sergio López-Estévez, Lamorna Brown Swigart, Marie-Eve Beaulieu, Jonathan R Whitfield, Babita Madan, David M Virshup, Gerard I Evan, Laura Soucek
The Wnt signaling receptor Fzd9 is essential for Myc-driven tumorigenesis in pancreatic islets. Life science alliance 4 (5) (2021)
Jonathan M Philpott, Rajesh Narasimamurthy, Clarisse G Ricci, Alfred M Freeberg, Sabrina R Hunt, Lauren E Yee, Rebecca S Pelofsky, Sarvind M Tripathi, David M Virshup, Carrie L Partch
Casein kinase 1 dynamics underlie substrate selectivity and the PER2 circadian phosphoswitch. eLife 9 (2020)
Jia Yu, Permeen A Mohamed Yusoff, Daniëlle T J Woutersen, Pamela Goh, Nathan Harmston, Ron Smits, David M Epstein, David M Virshup, Babita Madan
The Functional Landscape of Patient-Derived RNF43 Mutations Predicts Sensitivity to Wnt Inhibition. Cancer research 80 (24) (2020)
Nathan Harmston, Jun Yi Stanley Lim, Oriol Arqués, Héctor G Palmer, Enrico Petretto, David M Virshup, Babita Madan
Widespread Repression of Gene Expression in Cancer by a Wnt/β-Catenin/MAPK Pathway. Cancer research 81 (2) (2020)
Shusaku Masuda, Rajesh Narasimamurthy, Hikari Yoshitane, Jae Kyoung Kim, Yoshitaka Fukada, David M Virshup
Mutation of a PER2 phosphodegron perturbs the circadian phosphoswitch. Proceedings of the National Academy of Sciences of the United States of America 117 (20) (2020)
Kyunghee Lee, Mayumi Kitagawa, Pei Ju Liao, David M Virshup, Sang Hyun Lee
A Ras-LSD1 axis activates PI3K signaling through PIK3IP1 suppression. Oncogenesis 9 (1) (2020)
Zheng Zhong, David M Virshup
Wnt Signaling and Drug Resistance in Cancer. Molecular pharmacology 97 (2) (2019)
Naushad Moti, Jia Yu, Gaelle Boncompain, Franck Perez, David M Virshup
Wnt traffic from endoplasmic reticulum to filopodia. PloS one 14 (2) (2019)
Siti Farah Bte Fadhlullah, Nurashikin Bte Abdul Halim, Jacqueline Y T Yeo, Rachel L Y Ho, Phoebe Um, Beng Ti Ang, Carol Tang, Wai H Ng, David M Virshup, Ivy A W Ho
Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness. Oncogene 38 (27) (2019)
Zheng Zhong, Sugunavathi Sepramaniam, Xin Hui Chew, Kris C Wood, May Ann Lee, Babita Madan, David M Virshup
PORCN inhibition synergizes with PI3K/mTOR inhibition in Wnt-addicted cancers. Oncogene 38 (40) (2019)
Muhammad Idris, Nathan Harmston, Enrico Petretto, Babita Madan, David M Virshup
Broad regulation of gene isoform expression by Wnt signaling in cancer. RNA (New York, N.Y.) 25 (12) (2019)
Babita Madan, Mitchell J McDonald, Gabrielle E Foxa, Cassandra R Diegel, Bart O Williams, David M Virshup
Bone loss from Wnt inhibition mitigated by concurrent alendronate therapy. Bone research 6 (2018)
Gediminas Greicius, Zahra Kabiri, Kristmundur Sigmundsson, Chao Liang, Ralph Bunte, Manvendra K Singh, David M Virshup
PDGFRα+ pericryptal stromal cells are the critical source of Wnts and RSPO3 for murine intestinal stem cells in vivo. Proceedings of the National Academy of Sciences of the United States of America 115 (14) (2018)
Rajesh Narasimamurthy, Sabrina R Hunt, Yining Lu, Jean-Michel Fustin, Hitoshi Okamura, Carrie L Partch, Daniel B Forger, Jae Kyoung Kim, David M Virshup
CK1δ/ε protein kinase primes the PER2 circadian phosphoswitch. Proceedings of the National Academy of Sciences of the United States of America 115 (23) (2018)
Benjamin Mattes, Yonglong Dang, Gediminas Greicius, Lilian Tamara Kaufmann, Benedikt Prunsche, Jakob Rosenbauer, Johannes Stegmaier, Ralf Mikut, Suat Özbek, Gerd Ulrich Nienhaus, Alexander Schug, David M Virshup, Steffen Scholpp
Wnt/PCP controls spreading of Wnt/β-catenin signals by cytonemes in vertebrates. eLife 7 (2018)
Jean-Michel Fustin, Rika Kojima, Kakeru Itoh, Hsin-Yi Chang, Shiqi Ye, Bowen Zhuang, Asami Oji, Shingo Gibo, Rajesh Narasimamurthy, David M Virshup, Gen Kurosawa, Masao Doi, Ichiro Manabe, Yasushi Ishihama, Masahito Ikawa, Hitoshi Okamura
Two Ck1δ transcripts regulated by m6A methylation code for two antagonistic kinases in the control of the circadian clock. Proceedings of the National Academy of Sciences of the United States of America 115 (23) (2018)
Anshula Alok, Zhengdeng Lei, Narendra Suhas Jagannathan, Simran Kaur, Nathan Harmston, Steven G Rozen, Lisa Tucker-Kellogg, David M Virshup
Wnt proteins synergize to activate β-catenin signaling. Journal of cell science 130 (9) (2017)
Gracie Wee Ling Eng, null Edison, David M Virshup
Site-specific phosphorylation of casein kinase 1 δ (CK1δ) regulates its activity towards the circadian regulator PER2. PloS one 12 (5) (2017)
Babita Madan, Matthew P Walker, Robert Young, Laura Quick, Kelly A Orgel, Meagan Ryan, Priti Gupta, Ian C Henrich, Marc Ferrer, Shane Marine, Brian S Roberts, William T Arthur, Jason D Berndt, Andre M Oliveira, Randall T Moon, David M Virshup, Margaret M Chou, Michael B Major
USP6 oncogene promotes Wnt signaling by deubiquitylating Frizzleds. Proceedings of the National Academy of Sciences of the United States of America 113 (21) (2016)
Zahra Kabiri, Akihiko Numata, Akira Kawasaki, null Edison, Daniel G Tenen, David M Virshup
Wnts are dispensable for differentiation and self-renewal of adult murine hematopoietic stem cells. Blood 126 (9) (2015)
D G R Yim, S Ghosh, G R Guy, David M Virshup
Casein kinase 1 regulates Sprouty2 in FGF-ERK signaling. Oncogene 34 (4) (2014)

David M Virshup.css-eqlu8i{font-size:small;padding-left:4px;} (David Virshup, D M Virshup)

Publication Activity (10 Years)

Top Topics

Top Venues

David M Virshup (David Virshup, D M Virshup)