Lennart Bunch

ORCID

Publication Activity (10 Years)

Years Active: 2016-2024
Publications (10 Years): 20

Top Venues

Journal of medicinal chemistry

ACS chemical neuroscience

Chemistry (Weinheim an der Bergstrasse, Germany)

University of Copenhagen (PHD)

This page only lists publications with an associated author ORCID identifier.

Education History

University of Copenhagen

Denmark

PHD

Florida State University

United States

MSC :: Department of chemistry

Technical University of Denmark

Denmark

BSC :: Department of chemistry

Publications

Na Liu, Floriane Eshak, Fanny Malhaire, Isabelle Brabet, Laurent Prézeau, Emma Renard, Jean-Philippe Pin, Francine C Acher, Markus Staudt, Lennart Bunch
Design, Synthesis, Pharmacology, and In Silico Studies of (1 S ,2 S ,3 S )-2-(( S )-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu 2 Receptor Agonist. Journal of medicinal chemistry 67 (2) (2024)
Na Liu, Floriane Eshak, Fanny Malhaire, Isabelle Brabet, Laurent Prézeau, Emma Renard, Jean-Philippe Pin, Francine C Acher, Markus Staudt, Lennart Bunch
Design, Synthesis, Pharmacology, and In Silico Studies of (1 S ,2 S ,3 S )-2-(( S )-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu 2 Receptor Agonist. Journal of medicinal chemistry 67 (2) (2024)
Silke Buschbom-Helmke, Pengfei Wang, Anna Alcaide, Federico Miguez-Cabello, Mario Carta, Julio S Viotti, Birgitte Nielsen, Christophe Mulle, Derek Bowie, Flemming Steen Jørgensen, Darryl S Pickering, Lennart Bunch
Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5). Journal of medicinal chemistry 67 (16) (2024)
Silke Buschbom-Helmke, Pengfei Wang, Anna Alcaide, Federico Miguez-Cabello, Mario Carta, Julio S Viotti, Birgitte Nielsen, Christophe Mulle, Derek Bowie, Flemming Steen Jørgensen, Darryl S Pickering, Lennart Bunch
Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5). Journal of medicinal chemistry 67 (16) (2024)
Silke Buschbom-Helmke, Pengfei Wang, Anna Alcaide, Federico Miguez-Cabello, Mario Carta, Julio S Viotti, Birgitte Nielsen, Christophe Mulle, Derek Bowie, Flemming Steen Jørgensen, Darryl S Pickering, Lennart Bunch
Domoic Acid as a Lead for the Discovery of the First Selective Ligand for Kainate Receptor Subtype 5 (GluK5). Journal of medicinal chemistry (2024)
Na Liu, Floriane Eshak, Fanny Malhaire, Isabelle Brabet, Laurent Prézeau, Emma Renard, Jean-Philippe Pin, Francine C Acher, Markus Staudt, Lennart Bunch
Design, Synthesis, Pharmacology, and In Silico Studies of (1 S ,2 S ,3 S )-2-(( S )-Amino(carboxy)methyl)-3-(carboxymethyl)cyclopropane-1-carboxylic Acid (LBG30300): A Picomolar Potency Subtype-Selective mGlu 2 Receptor Agonist. Journal of medicinal chemistry (2024)
Markus Staudt, Adnan Cetin, Lennart Bunch
Transition Metal-Free Synthesis of meta-Bromo- and meta-Trifluoromethylanilines from Cyclopentanones by a Cascade Reaction. Chemistry (Weinheim an der Bergstrasse, Germany) 28 (10) (2022)
Christian B M Poulie, Younes Larsen, Cindie Leteneur, Gaël Barthet, Walden E Bjørn-Yoshimoto, Fanny Malhaire, Birgitte Nielsen, Jean-Phillippe Pin, Christophe Mulle, Darryl S Pickering, Lennart Bunch
( S )-2-Mercaptohistidine: A First Selective Orthosteric GluK3 Antagonist. ACS chemical neuroscience 13 (10) (2022)
Markus Staudt, Theis Sølling, Lennart Bunch
Synthesis of Polysubstituted Meta-Halophenols by Anion-Accelerated 2π-Electrocyclic Ring Opening. Chemistry (Weinheim an der Bergstrasse, Germany) 27 (42) (2021)
Fabao Zhao, Unai Atxabal, Sofia Mariottini, Feng Yi, James S Lotti, Nirvan Rouzbeh, Na Liu, Lennart Bunch, Kasper B Hansen, Rasmus Prætorius Clausen
Derivatives of ( R )-3-(5-Furanyl)carboxamido-2-aminopropanoic Acid as Potent NMDA Receptor Glycine Site Agonists with GluN2 Subunit-Specific Activity. Journal of medicinal chemistry 65 (1) (2021)
Silke Kayser, Jacob C Hansen, Markus Staudt, Aleksandra Moroz, Younes Larsen, Piero Temperini, Feng Yi, Jed T Syrenne, Niels Krogsgaard-Larsen, Stylianos Iliadis, Birgitte Nielsen, Kasper B Hansen, Darryl S Pickering, Lennart Bunch
Stereoselective Synthesis of New (2S,3R)-3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid Analogues Utilizing a C(sp3)-H Activation Strategy and Structure-Activity Relationship Studies at the Ionotropic Glutamate Receptors. ACS chemical neuroscience 11 (5) (2020)
Silke Kayser, Piero Temperini, Christian B M Poulie, Markus Staudt, Birgitte Nielsen, Darryl S Pickering, Lennart Bunch
A Diversity Oriented Synthesis Approach to New 2,3-trans-Substituted l-Proline Analogs as Potential Ligands for the Ionotropic Glutamate Receptors. ACS chemical neuroscience 11 (5) (2020)
Peng-Fei Wang, Anders A Jensen, Lennart Bunch
From Methaqualone and Beyond: Structure-Activity Relationship of 6-, 7-, and 8-Substituted 2,3-Diphenyl-quinazolin-4(3H)-ones and in Silico Prediction of Putative Binding Modes of Quinazolin-4(3H)-ones as Positive Allosteric Modulators of GABAA Receptors. ACS chemical neuroscience 11 (24) (2020)
Christian B M Poulie, Na Liu, Anders A Jensen, Lennart Bunch
Design, Synthesis, and Pharmacological Characterization of Heterobivalent Ligands for the Putative 5-HT2A/mGlu2 Receptor Complex. Journal of medicinal chemistry 63 (17) (2020)
Peng Wu, Walden E Bjørn-Yoshimoto, Markus Staudt, Anders A Jensen, Lennart Bunch
Identification and Structure-Activity Relationship Study of Imidazo[1,2-a]pyridine-3-amines as First Selective Inhibitors of Excitatory Amino Acid Transporter Subtype 3 (EAAT3). ACS chemical neuroscience 10 (10) (2019)
Christian B M Poulie, Anna Alcaide, Mikkel Krell-Jørgensen, Younes Larsen, Eloi Astier, Walden E Bjørn-Yoshimoto, Feng Yi, Jed T Syrenne, Morten Storgaard, Birgitte Nielsen, Karla A Frydenvang, Anders A Jensen, Kasper B Hansen, Darryl S Pickering, Lennart Bunch
Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters. ACS chemical neuroscience 10 (6) (2019)
Haigen Fu, Jielin Zhang, Pieter G Tepper, Lennart Bunch, Anders A Jensen, Gerrit J Poelarends
Chemoenzymatic Synthesis and Pharmacological Characterization of Functionalized Aspartate Analogues As Novel Excitatory Amino Acid Transporter Inhibitors. Journal of medicinal chemistry 61 (17) (2018)
Charles S Demmer, David Rombach, Na Liu, Birgitte Nielsen, Darryl S Pickering, Lennart Bunch
Revisiting the Quinoxalinedione Scaffold in the Construction of New Ligands for the Ionotropic Glutamate Receptors. ACS chemical neuroscience 8 (11) (2017)
Mikko Gynther, Ilaria Proietti Silvestri, Jacob C Hansen, Kasper B Hansen, Tarja Malm, Yevheniia Ishchenko, Younes Larsen, Liwei Han, Silke Kayser, Seppo Auriola, Aleksanteri Petsalo, Birgitte Nielsen, Darryl S Pickering, Lennart Bunch
Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist. Journal of medicinal chemistry 60 (23) (2017)
Niels Krogsgaard-Larsen, Claudia G Delgar, Karina Koch, Patricia M G E Brown, Charlotte Møller, Liwei Han, Tri H V Huynh, Stinne W Hansen, Birgitte Nielsen, Derek Bowie, Darryl S Pickering, Jette Sandholm Kastrup, Karla Frydenvang, Lennart Bunch
Design and Synthesis of a Series of l-trans-4-Substituted Prolines as Selective Antagonists for the Ionotropic Glutamate Receptors Including Functional and X-ray Crystallographic Studies of New Subtype Selective Kainic Acid Receptor Subtype 1 (GluK1) Antagonist (2S,4R)-4-(2-Carboxyphenoxy)pyrrolidine-2-carboxylic Acid. Journal of medicinal chemistry 60 (1) (2016)

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Publication Activity (10 Years)

Top Topics

Top Venues

Lennart Bunch