Darryl S Pickering

Publication Activity (10 Years)

Years Active: 2017-2021
Publications (10 Years): 10

Top Topics

Structural Basis

Cancer Stem Cells

Attention Deficit Hyperactivity Disorder

Molecular Dynamics Simulations

Top Venues

ACS chemical neuroscience

Journal of medicinal chemistry

The Journal of physiology

This page only lists publications with an associated author ORCID identifier.

Publications

Karla A Frydenvang, Darryl S Pickering, Jette Sandholm Kastrup
Structural basis for positive allosteric modulation of AMPA and kainate receptors. The Journal of physiology (2021)
Karla A Frydenvang, Darryl S Pickering, Giridhar U Kshirsagar, Giulia Chemi, Sandra Gemma, Desiree Sprogøe, Anne Mette Kærn, Simone Brogi, Giuseppe Campiani, Stefania Butini, Jette Sandholm Kastrup
Ionotropic Glutamate Receptor GluA2 in Complex with Bicyclic Pyrimidinedione-Based Compounds: When Small Compound Modifications Have Distinct Effects on Binding Interactions. ACS chemical neuroscience 11 (12) (2020)
Silke Kayser, Jacob C Hansen, Markus Staudt, Aleksandra Moroz, Younes Larsen, Piero Temperini, Feng Yi, Jed T Syrenne, Niels Krogsgaard-Larsen, Stylianos Iliadis, Birgitte Nielsen, Kasper B Hansen, Darryl S Pickering, Lennart Bunch
Stereoselective Synthesis of New (2S,3R)-3-Carboxyphenyl)pyrrolidine-2-carboxylic Acid Analogues Utilizing a C(sp3)-H Activation Strategy and Structure-Activity Relationship Studies at the Ionotropic Glutamate Receptors. ACS chemical neuroscience 11 (5) (2020)
Silke Kayser, Piero Temperini, Christian B M Poulie, Markus Staudt, Birgitte Nielsen, Darryl S Pickering, Lennart Bunch
A Diversity Oriented Synthesis Approach to New 2,3-trans-Substituted l-Proline Analogs as Potential Ligands for the Ionotropic Glutamate Receptors. ACS chemical neuroscience 11 (5) (2020)
Jakob Pallesen, Stine Møllerud, Karla A Frydenvang, Darryl S Pickering, Jan Bornholdt, Birgitte Nielsen, Diletta Pasini, Liwei Han, Laura Marconi, Jette Sandholm Kastrup, Tommy N Johansen
N1-Substituted Quinoxaline-2,3-diones as Kainate Receptor Antagonists: X-ray Crystallography, Structure-Affinity Relationships, and in Vitro Pharmacology. ACS chemical neuroscience 10 (3) (2019)
Stine Møllerud, Rie B Hansen, Jakob Pallesen, Piero Temperini, Diletta Pasini, Jan Bornholt, Birgitte Nielsen, Esmira Mamedova, Paulina Chalupnik, Ana V Paternain, Juan Lerma, Marta Diaz-delCastillo, Jesper T Andreasen, Karla A Frydenvang, Jette Sandholm Kastrup, Tommy N Johansen, Darryl S Pickering
N-(7-(1H-Imidazol-1-yl)-2,3-dioxo-6-(trifluoromethyl)-3,4-dihydroquinoxalin-1(2H)-yl)benzamide, a New Kainate Receptor Selective Antagonist and Analgesic: Synthesis, X-ray Crystallography, Structure-Affinity Relationships, and in Vitro and in Vivo Pharmacology. ACS chemical neuroscience 10 (11) (2019)
Christian B M Poulie, Anna Alcaide, Mikkel Krell-Jørgensen, Younes Larsen, Eloi Astier, Walden E Bjørn-Yoshimoto, Feng Yi, Jed T Syrenne, Morten Storgaard, Birgitte Nielsen, Karla A Frydenvang, Anders A Jensen, Kasper B Hansen, Darryl S Pickering, Lennart Bunch
Design and Synthesis of 2,3- trans-Proline Analogues as Ligands for Ionotropic Glutamate Receptors and Excitatory Amino Acid Transporters. ACS chemical neuroscience 10 (6) (2019)
Stefano Sainas, Piero Temperini, Jill C Farnsworth, Feng Yi, Stine Møllerud, Anders A Jensen, Birgitte Nielsen, Alice Passoni, Jette Sandholm Kastrup, Kasper B Hansen, Donatella Boschi, Darryl S Pickering, Rasmus Prætorius Clausen, Marco Lucio Lolli
Use of the 4-Hydroxytriazole Moiety as a Bioisosteric Tool in the Development of Ionotropic Glutamate Receptor Ligands. Journal of medicinal chemistry 62 (9) (2019)
Simone Brogi, Margherita Brindisi, Stefania Butini, Giridhar U Kshirsagar, Samuele Maramai, Giulia Chemi, Sandra Gemma, Giuseppe Campiani, Ettore Novellino, Paolo Fiorenzani, Jessica Pinassi, Anna Maria Aloisi, Mikko Gynther, Raminta Venskutonytė, Liwei Han, Karla Frydenvang, Jette Sandholm Kastrup, Darryl S Pickering
( S)-2-Amino-3-(5-methyl-3-hydroxyisoxazol-4-yl)propanoic Acid (AMPA) and Kainate Receptor Ligands: Further Exploration of Bioisosteric Replacements and Structural and Biological Investigation. Journal of medicinal chemistry 61 (5) (2018)
Mikko Gynther, Ilaria Proietti Silvestri, Jacob C Hansen, Kasper B Hansen, Tarja Malm, Yevheniia Ishchenko, Younes Larsen, Liwei Han, Silke Kayser, Seppo Auriola, Aleksanteri Petsalo, Birgitte Nielsen, Darryl S Pickering, Lennart Bunch
Augmentation of Anticancer Drug Efficacy in Murine Hepatocellular Carcinoma Cells by a Peripherally Acting Competitive N-Methyl-d-aspartate (NMDA) Receptor Antagonist. Journal of medicinal chemistry 60 (23) (2017)