Luca Laraia

Technical University of Denmark CWIS ORCID

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 23

Top Venues

Nature chemical biology

Angewandte Chemie (International ed. in English)

Chembiochem : a European journal of chemical biology

Chemical communications (Cambridge, England)

Technical University of Denmark

University of Cambridge (PHD)

This page only lists publications with an associated author ORCID identifier.

Affiliation History

Technical University of Denmark Nov 15 2017

Denmark

Assistant Professor :: Chemistry

Max-Planck-Institut für molekulare Physiologie - Oct 31 2017

Germany

Project Leader :: Chemical Biology

Max-Planck-Institut für molekulare Physiologie

Germany

Alexander von Humboldt post-doctoral fellow :: Chemical Biology

Cancer Research Technology Ltd Discovery Laboratories Cambridge

United Kingdom

PhD placement student :: Medicinal Chemistry

Institute of Cancer Research Jul 01 2008

United Kingdom

Intern :: Medicinal Chemistry

Novartis AG Jul 01 2007

Austria

Intern :: Discovery Chemistry

Education History

University of Cambridge Oct 01 2009

United Kingdom

PHD :: Chemistry

Publications

Nianzhe He, Laura Depta, Cecilia Rossetti, Lucie Caramelle, Marko Cigler, Hogan P Bryce-Rogers, Marine Michon, Oliver Rafn Dan, Joseph Hoock, Jinpeng Bi, Daniel Gillet, Alison Forrester, Georg E Winter, Luca Laraia
Inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation. Nature chemical biology (2024)
Laura Depta, Hogan P Bryce-Rogers, Nienke J Dekker, Anna Wiehl Bønke, Nicolo' Camporese, Mingxing Qian, Yuanjian Xu, Douglas F Covey, Luca Laraia
Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters. bioRxiv : the preprint server for biology (2024)
Laura Depta, Hogan P Bryce-Rogers, Nienke J Dekker, Anna Wiehl Bønke, Nicolo' Camporese, Mingxing Qian, Yuanjian Xu, Douglas F Covey, Luca Laraia
Endogenous and fluorescent sterols reveal the molecular basis for ligand selectivity of human sterol transporters. bioRxiv : the preprint server for biology (2024)
Marko Cigler, Hana Imrichova, Fabian Frommelt, Lucie Caramelle, Laura Depta, Andrea Rukavina, Chrysanthi Kagiou, J Thomas Hannich, Cristina Mayor-Ruiz, Giulio Superti-Furga, Sonja Sievers, Alison Forrester, Luca Laraia, Herbert Waldmann, Georg E Winter
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP. Nature chemical biology (2024)
Thomas Whitmarsh-Everiss, Zhou Wang, Cecilie Hauberg Hansen, Laura Depta, Elisa Sassetti, Oliver Rafn Dan, Axel Pahl, Sonja Sievers, Luca Laraia
Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Joseph G F Hoock, Cecilia Rossetti, Mesut Bilgin, Laura Depta, Kasper Enemark-Rasmussen, John C Christianson, Luca Laraia
Identification of non-conventional small molecule degraders and stabilizers of squalene synthase. Chemical science 14 (45) (2023)
Mikkel Krell-Jørgensen, Habiburrahman Zulfikri, Magnus Grage Bonnevie, Frederik Simonsen Bro, Asmus Ougaard Dohn, Luca Laraia
Redshifted and thermally bistable one-way quantitative hemithioindigo-derived photoswitches enabled by isomer-specific excited state intramolecular proton transfer. Chemical communications (Cambridge, England) 59 (5) (2023)
Thomas Whitmarsh-Everiss, Zhou Wang, Cecilie Hauberg Hansen, Laura Depta, Elisa Sassetti, Oliver Rafn Dan, Axel Pahl, Sonja Sievers, Luca Laraia
Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Thomas Whitmarsh-Everiss, Zhou Wang, Cecilie Hauberg Hansen, Laura Depta, Elisa Sassetti, Oliver Rafn Dan, Axel Pahl, Sonja Sievers, Luca Laraia
Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds. Chembiochem : a European journal of chemical biology (2023)
Ruwei Yao, Anders A Jensen, Hogan P Bryce-Rogers, Katrine Schultz-Knudsen, Libin Zhou, Nicklas P Hovendal, Henrik Pedersen, Mariusz Kubus, Trond Ulven, Luca Laraia
Identification of 5-HT2 Serotonin Receptor Modulators through the Synthesis of a Diverse, Tropane- and Quinuclidine-alkaloid-Inspired Compound Library. Journal of medicinal chemistry (2023)
Thomas Whitmarsh-Everiss, Zhou Wang, Cecilie Hauberg Hansen, Laura Depta, Elisa Sassetti, Oliver Rafn Dan, Axel Pahl, Sonja Sievers, Luca Laraia
Identification of Biologically Diverse Tetrahydronaphthalen-2-ols through the Synthesis and Phenotypic Profiling of Chemically Diverse, Estradiol-Inspired Compounds. Chembiochem : a European journal of chemical biology 24 (5) (2023)
Mikkel Krell-Jørgensen, Habiburrahman Zulfikri, Magnus Grage Bonnevie, Frederik Simonsen Bro, Asmus Ougaard Dohn, Luca Laraia
Redshifted and thermally bistable one-way quantitative hemithioindigo-derived photoswitches enabled by isomer-specific excited state intramolecular proton transfer. Chemical communications (Cambridge, England) (2022)
Mikkel Krell-Jørgensen, Habiburrahman Zulfikri, Magnus Grage Bonnevie, Frederik Simonsen Bro, Asmus Ougaard Dohn, Luca Laraia
Redshifted and thermally bistable one-way quantitative hemithioindigo-derived photoswitches enabled by isomer-specific excited state intramolecular proton transfer. Chemical communications (Cambridge, England) (2022)
Cecilia Rossetti, Luca Laraia
Thermal Proteome Profiling Reveals Distinct Target Selectivity for Differentially Oxidized Oxysterols. ACS chemical biology 17 (7) (2022)
Elisa Sassetti, Mads Hartvig Clausen, Luca Laraia
Small-Molecule Inhibitors of Reactive Oxygen Species Production. Journal of medicinal chemistry 64 (9) (2021)
Joseph G F Hoock, Luca Laraia
Unravelling the Mode of Action of Furanoheliangolides through Total Synthesis and Chemical Proteomics. ACS central science 7 (6) (2021)
Thomas Whitmarsh-Everiss, Asger Hegelund Olsen, Luca Laraia
Identification of Inhibitors of Cholesterol Transport Proteins Through the Synthesis of a Diverse, Sterol-Inspired Compound Collection. Angewandte Chemie (International ed. in English) 60 (51) (2021)
Thomas Whitmarsh-Everiss, Luca Laraia
Small molecule probes for targeting autophagy. Nature chemical biology 17 (6) (2021)
George Karageorgis, Daniel J Foley, Luca Laraia, Susanne Brakmann, Herbert Waldmann
Pseudo Natural Products-Chemical Evolution of Natural Product Structure. Angewandte Chemie (International ed. in English) 60 (29) (2021)
Luca Laraia, Guillaume Garivet, Daniel J Foley, Nadine Kaiser, Sebastian Müller, Sarah Zinken, Thomas Pinkert, Julian Wilke, Dale Corkery, Axel Pahl, Sonja Sievers, Petra Janning, Christoph Arenz, Yaowen Wu, Raphaël Rodriguez, Herbert Waldmann
Image-Based Morphological Profiling Identifies a Lysosomotropic, Iron-Sequestering Autophagy Inhibitor. Angewandte Chemie (International ed. in English) 59 (14) (2020)
Daniel J Foley, Sarah Zinken, Dale P Corkery, Luca Laraia, Axel Pahl, Yao-Wen Wu, Herbert Waldmann
Phenotyping Reveals Targets of a Pseudo-Natural-Product Autophagy Inhibitor. Angewandte Chemie (International ed. in English) 59 (30) (2020)
Luca Laraia, Alexandra Friese, Dale P Corkery, Georgios Konstantinidis, Nelli Erwin, Walter Hofer, Hacer Karatas, Laura Klewer, Andreas Brockmeyer, Malte Metz, Beate Schölermann, Mridula Dwivedi, Lei Li, Pablo Rios-Munoz, Maja Köhn, Roland Winter, Ingrid R Vetter, Slava Ziegler, Petra Janning, Yao-Wen Wu, Herbert Waldmann
The cholesterol transfer protein GRAMD1A regulates autophagosome biogenesis. Nature chemical biology 15 (7) (2019)
Lucas Robke, Yushi Futamura, Georgios Konstantinidis, Julian Wilke, Harumi Aono, Zhwan Mahmoud, Nobumoto Watanabe, Yao-Wen Wu, Hiroyuki Osada, Luca Laraia, Herbert Waldmann
Discovery of the novel autophagy inhibitor aumitin that targets mitochondrial complex I. Chemical science 9 (11) (2018)

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Publication Activity (10 Years)

Top Topics

Top Venues

Luca Laraia