Georg E Winter (Georg Winter)

Publication Activity (10 Years)

Years Active: 2018-2024
Publications (10 Years): 52

Top Topics

Gold Nanoparticles

Top Venues

Journal of the American Chemical Society

ACS chemical biology

Nature chemical biology

This page only lists publications with an associated author ORCID identifier.

Publications

Fabian Offensperger, Gary Tin, Miquel Duran-Frigola, Elisa Hahn, Sarah Dobner, Christopher W Am Ende, Joseph W Strohbach, Andrea Rukavina, Vincenth Brennsteiner, Kevin Ogilvie, Chakravarthy B N Marella, Katharina Kladnik, Rodolfo Ciuffa, Jaimeen D Majmudar, S Denise Field, Ariel Bensimon, Luca Ferrari, Evandro Ferrada, Amanda Ng, Zhechun Zhang, Gianluca Degliesposti, Andras Boeszoermenyi, Sascha Martens, Robert Stanton, André C Müller, J Thomas Hannich, David Hepworth, Giulio Superti-Furga, Stefan Kubicek, Monica Schenone, Georg E Winter
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science (New York, N.Y.) 384 (6694) (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Nianzhe He, Laura Depta, Cecilia Rossetti, Lucie Caramelle, Marko Cigler, Hogan P Bryce-Rogers, Marine Michon, Oliver Rafn Dan, Joseph Hoock, Jinpeng Bi, Daniel Gillet, Alison Forrester, Georg E Winter, Luca Laraia
Inhibition of OSBP blocks retrograde trafficking by inducing partial Golgi degradation. Nature chemical biology (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Fabian Offensperger, Gary Tin, Miquel Duran-Frigola, Elisa Hahn, Sarah Dobner, Christopher W Am Ende, Joseph W Strohbach, Andrea Rukavina, Vincenth Brennsteiner, Kevin Ogilvie, Chakravarthy B N Marella, Katharina Kladnik, Rodolfo Ciuffa, Jaimeen D Majmudar, S Denise Field, Ariel Bensimon, Luca Ferrari, Evandro Ferrada, Amanda Ng, Zhechun Zhang, Gianluca Degliesposti, Andras Boeszoermenyi, Sascha Martens, Robert Stanton, André C Müller, J Thomas Hannich, David Hepworth, Giulio Superti-Furga, Stefan Kubicek, Monica Schenone, Georg E Winter
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science (New York, N.Y.) 384 (6694) (2024)
Georg E Winter
Extrapolating Lessons from Targeted Protein Degradation to Other Proximity-Inducing Drugs. ACS chemical biology (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Marko Cigler, Hana Imrichova, Fabian Frommelt, Lucie Caramelle, Laura Depta, Andrea Rukavina, Chrysanthi Kagiou, J Thomas Hannich, Cristina Mayor-Ruiz, Giulio Superti-Furga, Sonja Sievers, Alison Forrester, Luca Laraia, Herbert Waldmann, Georg E Winter
Orpinolide disrupts a leukemic dependency on cholesterol transport by inhibiting OSBP. Nature chemical biology (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature 627 (8002) (2024)
Oliver Hsia, Matthias Hinterndorfer, Angus D Cowan, Kentaro Iso, Tasuku Ishida, Ramasubramanian Sundaramoorthy, Mark A Nakasone, Hana Imrichova, Caroline Schätz, Andrea Rukavina, Koraljka Husnjak, Martin Wegner, Alejandro Correa-Sáez, Conner Craigon, Ryan Casement, Chiara Maniaci, Andrea Testa, Manuel Kaulich, Ivan Đikić, Georg E Winter, Alessio Ciulli
Targeted protein degradation via intramolecular bivalent glues. Nature (2024)
Chrysanthi Kagiou, Jose A Cisneros, Jakob Farnung, Joanna Liwocha, Fabian Offensperger, Kevin Dong, Ka Yang, Gary Tin, Christina S Horstmann, Matthias Hinterndorfer, Joao A Paulo, Natalie S Scholes, Juan Sanchez Avila, Michaela Fellner, Florian Andersch, J Thomas Hannich, Johannes Zuber, Stefan Kubicek, Steven P Gygi, Brenda A Schulman, Georg E Winter
Alkylamine-tethered molecules recruit FBXO22 for targeted protein degradation. Nature communications 15 (1) (2024)
Fabian Offensperger, Gary Tin, Miquel Duran-Frigola, Elisa Hahn, Sarah Dobner, Christopher W Am Ende, Joseph W Strohbach, Andrea Rukavina, Vincenth Brennsteiner, Kevin Ogilvie, Chakravarthy B N Marella, Katharina Kladnik, Rodolfo Ciuffa, Jaimeen D Majmudar, S Denise Field, Ariel Bensimon, Luca Ferrari, Evandro Ferrada, Amanda Ng, Zhechun Zhang, Gianluca Degliesposti, Andras Boeszoermenyi, Sascha Martens, Robert Stanton, André C Müller, J Thomas Hannich, David Hepworth, Giulio Superti-Furga, Stefan Kubicek, Monica Schenone, Georg E Winter
Large-scale chemoproteomics expedites ligand discovery and predicts ligand behavior in cells. Science (New York, N.Y.) 384 (6694) (2024)
Zuzanna Kozicka, Dakota J Suchyta, Vivian Focht, Georg Kempf, Georg Petzold, Marius Jentzsch, Charles Zou, Cristina Di Genua, Katherine Aleisha Donovan, Seemon Coomar, Marko Cigler, Cristina Mayor-Ruiz, Jonathan L Schmid-Burgk, Daniel Häussinger, Georg E Winter, Eric S Fischer, Mikołaj Słabicki, Dennis Gillingham, Benjamin L Ebert, Nicolas H Thomä
Design principles for cyclin K molecular glue degraders. Nature chemical biology (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society 145 (2) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society 145 (5) (2023)
Gang Xue, Jianing Xie, Matthias Hinterndorfer, Marko Cigler, Lara Dötsch, Hana Imrichova, Philipp Lampe, Xiufen Cheng, Soheila Rezaei Adariani, Georg E Winter, Herbert Waldmann
Discovery of a Drug-like, Natural Product-Inspired DCAF11 Ligand Chemotype. Nature communications 14 (1) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society 145 (5) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society 145 (5) (2023)
Amanda Ng, Fabian Offensperger, Jose A Cisneros, Natalie S Scholes, Monika Malik, Ludovica Villanti, Andrea Rukavina, Evandro Ferrada, J Thomas Hannich, Anna Koren, Stefan Kubicek, Giulio Superti-Furga, Georg E Winter
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS chemical biology 18 (12) (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society 145 (2) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society 145 (5) (2023)
Amanda Ng, Fabian Offensperger, Jose A Cisneros, Natalie S Scholes, Monika Malik, Ludovica Villanti, Andrea Rukavina, Evandro Ferrada, J Thomas Hannich, Anna Koren, Stefan Kubicek, Giulio Superti-Furga, Georg E Winter
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS chemical biology 18 (12) (2023)
Amanda Ng, Fabian Offensperger, Jose A Cisneros, Natalie S Scholes, Monika Malik, Ludovica Villanti, Andrea Rukavina, Evandro Ferrada, J Thomas Hannich, Anna Koren, Stefan Kubicek, Giulio Superti-Furga, Georg E Winter
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS chemical biology 18 (12) (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society 145 (2) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society 145 (5) (2023)
Amanda Ng, Fabian Offensperger, Jose A Cisneros, Natalie S Scholes, Monika Malik, Ludovica Villanti, Andrea Rukavina, Evandro Ferrada, J Thomas Hannich, Anna Koren, Stefan Kubicek, Giulio Superti-Furga, Georg E Winter
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS chemical biology 18 (12) (2023)
Amanda Ng, Fabian Offensperger, Jose A Cisneros, Natalie S Scholes, Monika Malik, Ludovica Villanti, Andrea Rukavina, Evandro Ferrada, J Thomas Hannich, Anna Koren, Stefan Kubicek, Giulio Superti-Furga, Georg E Winter
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS chemical biology 18 (12) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society 145 (5) (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society 145 (2) (2023)
Amanda Ng, Fabian Offensperger, Jose A Cisneros, Natalie S Scholes, Monika Malik, Ludovica Villanti, Andrea Rukavina, Evandro Ferrada, J Thomas Hannich, Anna Koren, Stefan Kubicek, Giulio Superti-Furga, Georg E Winter
Discovery of Molecular Glue Degraders via Isogenic Morphological Profiling. ACS chemical biology 18 (12) (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society 145 (2) (2023)
Alexander Hanzl, Eleonora Barone, Sophie Bauer, Hong Yue, Radosław P Nowak, Elisa Hahn, Eugenia V Pankevich, Anna Koren, Stefan Kubicek, Eric S Fischer, Georg E Winter
E3-Specific Degrader Discovery by Dynamic Tracing of Substrate Receptor Abundance. Journal of the American Chemical Society 145 (2) (2023)
Lennart Enders, Marton Siklos, Jan Borggräfe, Stefan Gaussmann, Anna Koren, Monika Malik, Tatjana Tomek, Michael K Schuster, Jiří Reiniš, Elisa Hahn, Andrea Rukavina, Andreas Reicher, Tamara Casteels, Christoph Bock, Georg E Winter, J Thomas Hannich, Michael Sattler, Stefan Kubicek
Pharmacological perturbation of the phase-separating protein SMNDC1. Nature communications 14 (1) (2023)
Miquel Duran-Frigola, Marko Cigler, Georg E Winter
Advancing Targeted Protein Degradation via Multiomics Profiling and Artificial Intelligence. Journal of the American Chemical Society (2023)
Alexander Hanzl, Ryan Casement, Hana Imrichova, Scott J Hughes, Eleonora Barone, Andrea Testa, Sophie Bauer, Jane Wright, Matthias Brand, Alessio Ciulli, Georg E Winter
Functional E3 ligase hotspots and resistance mechanisms to small-molecule degraders. Nature chemical biology (2022)
Gary Tin, Georg E Winter
CIDE-stepping E3s. Nature chemical biology 19 (1) (2022)
Barbara Peter, Gregor Eisenwort, Irina Sadovnik, Karin Bauer, Michael Willmann, Thomas Rülicke, Daniela Berger, Gabriele Stefanzl, Georg Greiner, Gregor Hoermann, Alexandra Keller, Dominik Wolf, Martin Čulen, Georg E Winter, Thomas Hoffmann, Ana-Iris Schiefer, Wolfgang R Sperr, Johannes Zuber, Jiří Mayer, Peter Valent
BRD4 degradation blocks expression of MYC and multiple forms of stem cell resistance in Ph + chronic myeloid leukemia. American journal of hematology 97 (9) (2022)
Gary Tin, Georg E Winter
CIDE-stepping E3s. Nature chemical biology 19 (1) (2022)
Sandra Schick, Sarah Grosche, Katharina Eva Kohl, Danica Drpic, Martin G Jaeger, Chakravarthy B N Marella, Hana Imrichova, Jung-Ming G Lin, Gerald Hofstätter, Michael K Schuster, André Figueiredo Rendeiro, Anna Koren, Mark Petronczki, Christoph Bock, André C Müller, Georg E Winter, Stefan Kubicek
Acute BAF perturbation causes immediate changes in chromatin accessibility. Nature genetics 53 (3) (2021)
Alessio Ciulli, Lawrence Hamann, Wolfgang Jahnke, Amit S Kalgutkar, Thomas Magauer, Tobias Ritter, Vicky Steadman, Scott D Williams, Georg E Winter, Klemens Hoegenauer, Karl Heinz Krawinkler, Antonia F Stepan
The 2nd Alpine Winter Conference on Medicinal and Synthetic Chemistry. ChemMedChem 16 (15) (2021)
Martin G Jaeger, Björn Schwalb, Sebastian D Mackowiak, Taras Velychko, Alexander Hanzl, Hana Imrichova, Matthias Brand, Benedikt Agerer, Someth Chorn, Behnam Nabet, Fleur M Ferguson, André C Müller, Andreas Bergthaler, Nathanael S Gray, James E Bradner, Christoph Bock, Denes Hnisz, Patrick Cramer, Georg E Winter
Selective Mediator dependence of cell-type-specifying transcription. Nature genetics 52 (7) (2020)
Cristina Mayor-Ruiz, Sophie Bauer, Matthias Brand, Zuzanna Kozicka, Marton Siklos, Hana Imrichova, Ines H Kaltheuner, Elisa Hahn, Kristina Seiler, Anna Koren, Georg Petzold, Michaela Fellner, Christoph Bock, André C Müller, Johannes Zuber, Matthias Geyer, Nicolas H Thomä, Stefan Kubicek, Georg E Winter
Rational discovery of molecular glue degraders via scalable chemical profiling. Nature chemical biology 16 (11) (2020)
Mette Ishoey, Someth Chorn, Natesh Singh, Martin G Jaeger, Matthias Brand, Joshiawa Paulk, Sophie Bauer, Michael A Erb, Katja Parapatics, André C Müller, Keiryn L Bennett, Gerhard F Ecker, James E Bradner, Georg E Winter
Translation Termination Factor GSPT1 Is a Phenotypically Relevant Off-Target of Heterobifunctional Phthalimide Degraders. ACS chemical biology 13 (3) (2018)
Johannes W Bigenzahn, Giovanna M Collu, Felix Kartnig, Melanie Pieraks, Gregory I Vladimer, Leonhard X Heinz, Vitaly Sedlyarov, Fiorella Schischlik, Astrid Fauster, Manuele Rebsamen, Katja Parapatics, Vincent A Blomen, André C Müller, Georg E Winter, Robert Kralovics, Thijn R Brummelkamp, Marek Mlodzik, Giulio Superti-Furga
LZTR1 is a regulator of RAS ubiquitination and signaling. Science (New York, N.Y.) 362 (6419) (2018)